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Effect of stimulus pulse duration on intraoperative somatosensory evoked potential (SEP) monitoring.

The effect of the stimulus duration on the amplitude and latency of intraoperative somatosensory evoked potential (SEP) was studied in 30 patients with idiopathic scoliosis undergoing surgery. Constant current square-wave electrical stimulation was applied to the posterior tibial nerve at a rate of 5.1 Hz. The effects of both the pulse duration and the stimulus current density on the intraoperative SEP were evaluated. Amplitudes and latencies of SEP were analyzed by one-way parametric analysis of variance. SEP signal recording was found to be difficult if the stimulus duration was less than 0.05 ms. The stimulus duration had no significant effect on the latencies of the SEP, but the amplitude of the SEP showed significant changes with differing stimulus durations. The SEP amplitudes were found with significant increases in pulse durations less than 0.3 ms. Stimulus pulse duration has a significant effect on SEP amplitude, and this should be taken into consideration during intraoperative SEP monitoring. A pulse duration of 0.3 ms is recommended for SEP using posterior tibial nerve stimulation.