{'fraction_non_alphanumeric': 0.012797074954296161, 'fraction_numerical': 0.0018281535648994515, 'mean_word_length': 5.447058823529412, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Dramatic reduction of proteinuria in diabetic nephropathy by the use of spironolactone.

The addition of spironolactone to the combination of an ACE inhibitor, and ARB, and a direct renin inhibitor brought about dramatic and sustained reversal of 4-plus proteinuria in a patient with diabetes mellitus and hypertension. Spironolactone may be a valuable addition to the therapeutic armamentarium for such patients, with the caveat that the spironolactone dose should be increased gradually and with frequent monitoring of the serum potassium level.