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Axonal swelling and spheroids in Taenia solium neurocysticercosis

I read with interest the paper of Mejia Maza and coworkers on the presence of axonal swelling and spheroids development in humans, pigs and rats with neurocysticercosis [8]. Taking the advantage of a novel rat model of Taenia solium cysticercosis, the authors found not only local inflammatory changes in the brain parenchyma surrounding cysticerci, but axonal swelling with spheroid formation at a considerable distance from the parasites. From what can be understood from their work, these axons originated in neurons located near the parasites that were damaged as the result of inflammatory changes surrounding parenchymal brain cysticerci. This article is protected by copyright. All rights reserved.