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Longitudinal Label‐Free Two‐Photon Microscopy of Cellular Healing Processes in Non‐Ablative Fractional Laser Wounds

Wound healing is an important biomedical problem with various associated complications. Although cutaneous wound healing has been studied in vivo extensively using various optical imaging methods, early‐stage cellular healing processes were difficult to study due to scab formation. The objective of this study is to demonstrate that minimal laser wounds and optical microscopy can access the detailed cellular healing processes of cutaneous wounds from the early stage.