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BRAINSTEM AUDITORY EVOKED RESPONSES(BAER)IN PREMATURE INFANTS WITH SEVERE INTRAVENTRICULAR HEMORRHAGE (IVH)

Higher incidence of BAER abnormalities were found in a group of very low birthweight infants with severe IVH compared to a heavier group without IVH.Nineteen infants (BW:1.2±0.3kg,GA:28±1 wk) with IVH and 42 (BW:2.3±1.2kg,GA:36±4wks) control infants were examined at post-conceptual age ranging from 33 to 52 weeks. Monaural stimulation at 16 clicks per second and 70 decibel intensity was used and the presence, stability, and appearance of Waves I, III, and V were evaluated.Six of 19 IVH (32%) and 1 of 42 control (2%) infants manifest BAER abnormalities. This difference was significant at the p<0.02 level. In the IVH group, 3 of 8 infants with ventricular dilatation (Grade 3) and 3 of 11 infants with intracerebral hemorrhage (Grade 4) had abnormal responses.Seizures, asphyxia, and male sex significantly correlated with the presence of abnormal wave forms. However, these factors lost their significance when the analysis of variance was corrected for the presence of IVH.In this group of infants, severe intraventricular hemorrhage is the most important etiology for the existence of brainstem dysfunction as measured by BAER.