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LIFE WITHOUT LIMBS: TETRA-AMELIA

Address for Correspondence: Dr. Jeneeta Baa, Assistant Professor, Department of Anatomy, GVP Institute of health care and medical technology, Visakhapatnam, Andhra Pradesh 530048, India. E-Mail: drjeneetabaa@gmail.com Amelia is defined as the complete absence of the skeletal parts of a limb. Tetraamelia, is the absence of all the four limbs is a very rare condition with an incidence range of 1.5–4/100,000 births. Many factors causing various limb defects are genetic, environmental (teratogens), vascular compromise by amniotic bands and conditions like oligohydraminos and maternal diabetes. Point mutation in the WNT gene plays a major role in causing limb defects.