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[Fibromyalgia in adults-a mainly psychosomatic entity].

This paper presents the clinical entity of fibromyalgia and is a review of the research data on its pathogenesis and treatment. Current data indicate that bio-genetic factors associated mainly with the mechanisms of pain, combined with serious stressfull experiences, may be responsible for causing the disease. The contribution of neurotransmitters (such as substance P), of hormones (in particular of the hypothalamus-pituitar y axis), of sleep disturbance, of brain circuits linked to the perception of pain is discussed. The treatment of fibromyalgia is complex and involves in particular antidepressant therapy in combination with psychoeducational cognitive and behavioral interventions and rehabilitation programs. In the diagnosis and treatment of the disease, which, without assistance can become torturing, many specialties of health professionals are involved.