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Malignant Soft Tissue Masses

Chapter 66 discusses malignant soft tissue masses. Soft tissue malignancies are less common than those of benign origin but should be in the differential diagnosis for any soft tissue mass. Malignant soft tissue tumors have a wide range of clinical and imaging appearances, which can present a diagnostic challenge. If the imaging features of the soft tissue mass are not entirely characteristic for a benign diagnosis, biopsy should be performed. After initial radiographs, MRI is considered the best imaging modality to characterize malignant soft tissue lesions. Prompt diagnosis is critical because a diagnostic delay is associated with a worse clinical outcome.