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High-Dose Urokinase Therapy for the Lysis of a Central Venous Catheter-Related Thrombus in a Young Patient with Hodgkin's Disease

Correspondence to: The Cleveland Clinic Children’s Hospital, Department of Pediatrics, Desk A 120, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, Ohio 44195. The following case report describes how a potentially life-threatening condition, namely a large right atrial catheter-related thrombus, can present inconspicuously. Since this condition can be easily managed, it is important the pediatricians, who are now dealing more and me with patients who have large indwelling catheters and are therefore at high risk for the development of catheter-related clots, be aware of the possibility of this complication and of the therapeutic modalities. The authors describe a seventeen-year-old female patient with Hodgkin’s disease, with an indwelling Hickman@ Single Lumen Vascular Access Catheter (Danol Inc., Cranston, RI) who developed