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Sarcoidosis, galactorrhea, and amenorrhea: 2 Autopsy cases, 1 with chiari‐frommel syndrome

Two women with amenorrhea and galactorrhea, 1 with Chiari‐Frommel syndrome, died of cerebral sarcoidosis. At autopsy in both cases, sarcoid granulomas were numerous in the hypothalamus, but the pituitary appeared normal and did not contain increased prolactin as determined by immunoperoxidase technique. These are the first autopsy reports of sarcoidosis with galactorrhea and of Chiari‐Frommel syndrome in the absence of pituitary adenoma.