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Lipoid proteinosis in South Africa.

A genealogical study of lipoid proteinosis indicates that most, if not all, South African patients are probably descendants of a brother and sister, Jacob and Elsje Cloete, who settled in the Cape early in the latter half of the 17th century. It is suggested that a similar genealogical study be undertaken of patients in other countries to see whether more of them could be traced to the same family.