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PATENT DUCTUS ARTERIOSUS IN OLDER PEOPLE

Please observe that BUN, uric acid, and lactic acid dehydrogenase all elevated as the weight loss and dementia worsened. It is interesting to note that BUN, uric acid, and lactic acid dehydrogenase also elevate in cancer patients who lose weight. Recent research points to interleukin 6 as an important mediator of weight loss in cancer patients and animals. Since interleukin 6 has been found to be high in the brains of AD patients, it is possible that weight loss in cancer and in Alzheimer’s disease patients may be caused by a common mechanism. We would be interested in knowing if other clinicians have noted elevations of BUN, uric acid, and LDH in Alzheimer’s disease patients with severe weight loss.