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Nutritional therapy for the treatment of pediatric Crohn’s disease

Crohn’s disease and ulcerative colitis are lifelong conditions with particular effects upon nutrition, especially in children and adolescents. Various therapies are available for these conditions but there remains no cure. Over the last decades, exclusive enteral nutrition (EEN) has been demonstrated to have efficacy in the induction of remission, along with numerous other nutritional and inflammatory benefits. This article reviews the benefits and outcomes associated with EEN in Crohn’s disease. The potential mechanisms of this therapy are highlighted, along with factors that are barriers to the wider use of EEN.