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Is there P300 asymmetry in schizophrenia?

To the Editor.— We wish to add an important update with respect to the review of our laboratory's work on the auditory P300 event-related potential in schizophrenia that was presented in the recent carefully prepared report of Pfefferbaum et al. 1 This work affirmed the importance of the P300 in schizophrenia research but failed to confirm our repeated finding of a lateralized left We have found the P300 asymmetry in schizophrenics using only the waveform associated with the target stimulus, 2 the waveform used by Pfefferbaum et al. 1 Our previous studies used a waveform subtraction paradigm. 3 Our