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TRANSFERABLE MULTIPLE ANTIBIOTIC RESISTANCE AMONGST SHIGELLA STRAINS ISOLATED IN MELBOURNE BETWEEN 1952 AND 1968

Forty‐two of 48 antibiotic‐resistant shigellæ selected from strains isolated at the Children's Cottages, Kew, Melbourne, between 1952 and 1968, were found to harbour transferable antibiotic‐resistance factors (R‐factors). These R‐factors confer resistance to one or more of the antibacterial agents streptomycin, tetracycline, chloramphenicol and sulphonamides. The criteria used for establishing R‐factor‐mediated drug resistance and the significance of the R‐factor‐bearing strains discovered are discussed.