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[Effect of prostaglandin F2 alpha on temperature regulation in the rabbit].

In unanesthetized rabbits, i.v. administration of prostaglandin F2 alpha (PgF2 alpha) evokes a slight hyperthermic response whereas its intrathalamic injection evokes rather obvious one. Its injection in anterior hypothalamus leads to a greater hyperthermic effect as compared with the posterior hypothalamus. PgF2 alpha seems to act both on chemical and physical mechanisms of the organism thermoregulative function.