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Review On Different Vesicular Drug Delivery Systems (VDDSs) And Their Applications.

BACKGROUND
The vesicular drug delivery systems (VDDSs) are colloidal dispersions, which can be described as highly ordered assemblies composed of one or more concentric bilayers formed as a result of the self-assembling of amphiphilic building blocks in the presence of water.


OBJECTIVES
VDDSs are important to target the entrapped drugs at specific sites inside the body, control the drug release, enhance the drug bioavailability, and reduce the undesired side effects.


METHODS
There are different types of VDDSs suitable for the entrapment of both hydrophilic and lipophilic drugs. According to the composition, VDDSs are classified into lipid-based and non-lipid-based VDDSs.


RESULTS
There are different types of VDDSs which include liposomes, ethosomes, transferosomes, ufasomes, colloidosomes, cubosomes, niosomes, bilosomes, aquasomes, etc. Conclusion: This review article aims to address the different types of VDDSs, their advantages and disadvantages, and their therapeutic applications.