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Inhibition of fungal exopolysaccharide production by chemical antifoams

Attempts to control foam production in exopolysaccharide synthesising cultures of Acremonium persicinum in aerobic fermentation with polypropylene glycol (PPG) 2025 led to a marked reduction in yield. Similar effects were seen with polysaccharide producing cultures of Epicoccum purpurascens, but not with Aureobasidium pullulans. The effects of other chemical antifoams on polysaccharide production in A. persicinum were examined, and no inhibition was noticed with any silicone‐based compound.