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Proximal femoral focal deficiency and fibular hemimelia associated with misoprostol use: a case report.

Body weight was 5.8 kg (third centile), height was 19.5 cm (third centile), and the head circumference was 17.4 cm (third centile). The child was well in appearance and showed no facial dysmorphism. Examination indicated significant shortening of both thighs, flexion contractures of 451 at both knees, and severe equinovalgus deformity of both feet. Oligodactyly was also observed in both feet, showing four digits including the great toe on the right and three digits including the great toe on the left. The upper limbs were bilaterally symmetrical and normal in appearance; however, examination of the right hand showed two functional digits, an apparent thumb and a second digit, whereas the left hand had five digits with incomplete webbing at the ring–little interspace. On chest examination, there was no cardiac murmur and breath sounds were normal. Abdominal examination was normal, and normal female genitalia were observed. Ophthalmologic examination was normal, and neither facial palsy nor cranial nerve involvement was noted.