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Asymptomatic Chlamydia trachomatis infections among sexually active men.

Genital infections with Chlamydia trachomatis have been recognized as a significant public health problem in the United States. Studies of normal pregnant women have suggested that a large reservoir of asymptomatic chlamydial infection is present in poor, inner-city populations [1,2]. Among normal pregnant women, young age, out-of-wedlock conception, and multiple sexual exposures have been recognized as risk factors for endocervical infections with C. trachomatis [1-3]. Young age has also been shown to be a risk factor for C. trachomatis infection in men attending a sexually transmitted disease clinic [4]. Considerably less is known about asymptomatic infections in men in settings other than sexually transmitted disease clinics. Because men may be more likely to transmit sexually transmitted pathogens to susceptible female partners than vice versa [5], men who are unaware that they are infected are likely to play a critical role in maintaining the high prevalence of chlamydial infections in certain populations.