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Analysis of Telomere Length in Aging and Age ‐Related Illness

The purpose of this study was to create a detailed analysis of the factual concepts and theoretical principles of telomeres and their application in aging and disease. The analysis is based on the current genetic knowledge of the telomere and its main enzyme telomerase as well considerayion and evaluation of theoretical applications of telomere status. The assessment of telomere lengths were the main concepts being analyzed in this thesis. This area of genetics is being studied to explore its many benefits to understanding key functions of the human chromosome as it relates to wellness and disease during the lifespan. There are many challenges facing the advancement of telomere studies and its application to disease and wellness. For the purposes of this analysis the telomere length and its role in the immune system and aging were the focus of the meta analysis. A strong immune system and ability to aid in the prevention and proliferation of disease can theoretically be associated with the telomere. Free radical and oxidative stress of the cell may also be comprising factors. Cancer is one of the largest chalenges facing modern medicine today. There are many theoretical correlations between the cancer cell mortality and the length of the telomere. Additionally, the amount of telomerase can influence the life span of the cancer cell and making the cell immortal. A greater understanding of this aspect of the chromosome will encourage more research and testing of the telomere. Published data from meta‐analysis and research have shown interesting results in the correlation of decreasing telomere lengths with aging diseases and cancers. Further research may be extremely valuable to patients suffering from age associated disease and tumor related cancers.