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["Multiple organ failure syndrome". Nature of the concept and correctness of the nomenclature].

The syndrome principle of studying complex pathological processes is justified if the key link of the pathogenesis is determined. The multi-organ systemic dysfunction is due to altered synergism of all visceral functions rather than to the sum of functional alterations of several organs. The main ideas and regularities of the synergism as the fundamental theoretical directions determine the coordination of vital activity and the probability of its disturbance depending on genetically determined and other factors. Grounds are presented for the prospects of using the Mandelbroth's fractals and regularities of synergism in creation of the prognostic dynamic models in the organism's extreme states.