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Current trends in pharmacological approaches for treatment and management of acute pancreatitis – a review

Acute pancreatitis (AP) is an inimical disorder associated with overall mortality rates between 10‐15%. It is a disorder of the exocrine pancreas which is characterized by local and systemic inflammatory responses primarily driven by oxidative stress and death of pancreatic acinar cells. The severity of AP ranges from mild pancreatic edema with complete recuperative possibilities to serious systemic inflammatory response resulting in peripancreatic/pancreatic necrosis, multiple organ failure, and death.