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Recurrent aphthous ulcers and nicotine

The aim of this study was to investigate the effect of nicotine, in the form of Nicorette tablets, on aphthous ulcers in non‐smoking patients. The study was prompted by the observations that smokers are less likely to suffer from mouth ulcers, that some smokers on quitting develop them, and that patients on nicotine replacement therapy are less likely to develop ulcers than those having other types of smoking cessation therapy.