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Holographic Laser Interferometry For Detection Of Tumors In The Rabbit Urinary Bladder

Holographic interferometric investigations were performed in male giant rabbits (n=10) with and without bladder tumors. Double impulse ruby laser technique was able to detect elasticity changes of the bladder wall caused by tumors. The reproducibility of the experimental results was tested in vivo and in vitro. Healthy and tumorous changed regions of the bladder show a different stretch behavior in response to alterations of internal pressure.The method was found applicable to organic tissue without destruction of the tissue. Holographic interferometry was found to be sensitive method for distinction between normal and tumorous regions of the bladder wall. The results encourage the construction of a designed endoscope for holographic medical diagnostics.