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A brief history of modern crystallography and how taking risks run in the family

The history of X-ray crystallography and X-ray diffraction, and their important contributions to science as a whole, is profound. From the first images of Wilhelm Roentgen and Madame Curie taking an X-ray image of a women’s hand, through the discovery of the structure of DNA by Watson and Crick, to the discovery of vitamin B12 by Dorothy Hodgkin, the importance of these techniques is obvious. The fact that these techniques have moved from being solely utilized in research projects performed by specialized crystallographers to now becoming routine tools for many scientists is in many ways due to the legacy of Dr Jerry Atwood. Dr Atwood’s role in the history of Xray crystallography, and his willingness to embrace this cutting-edge instrument, has helped shape research and impacted the careers of many scientists. In a very personal way, I have had the pleasure, and good fortune, to be part of the Atwood research family. While working as a PhD student in Dr Robin Rogers’ research group, I was introduced to X-ray crystallography in the study of coordination compounds. At the University of Wisconsin–Madison, I worked on solving structures related to the synthesis pathway for vitamin B12. I have even had the honor of sharing an office at Argonne National Laboratory with Dr Herbert Diamond, who is a coauthor of the articles that describe the discovery of Einsteinium and Fermium. Currently, I work for the company that sold the first X-ray tube to Dr Roentgen. Looking back on my career, I am aware that my success builds on the work of my research family and all that I have learned from them. The history and the future of X-ray crystallography owes much to Dr Atwood and all of the researchers who embraced this technology.