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Swelling Characterization of Double Sensitive Hydroxypropylcellulose / Sodium Alginate Hydrogel

A series of temperature and pH responsive hydrogels was synthesized by using hydroxypropylcellulose (HPC) as temperature sensitivity material and the natural material, sodium alginate (SA) as pH sensitivity material. The effect of SA to LCST has been studied and the mechanism of the influence has been presented. In addition, the swelling ratio and controlling factor of swelling process were all researched in this paper. The main results obtained are as follows: the LCST decreased gradually as added SA into HPC; the HPC/SA hydrogel responded both temperature and pH value of the medium; the swelling ratio reached maximum value as pH value of 6.