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Sharper in the morning: Cognitive sundowning revealed with high‐frequency smartphone testing

In Alzheimer’s disease (AD), patients and caregivers often report a pattern of increasing cognitive and behavioral difficulties in evening hours, known colloquially as “sundowning.” Here, we describe the first known attempt to capture circadian fluctuations in cognition in humans at risk for AD using a novel smartphone assessment that samples cognition rapidly and repeatedly over a 7‐day period. We hypothesized that cognitive sundowning would manifest among individuals with abnormal AD biomarkers, even in preclinical stages of AD.