{'fraction_non_alphanumeric': 0.032767700409596257, 'fraction_numerical': 0.02399063779988297, 'mean_word_length': 4.916955017301038, 'pattern_counts': {'":': 0, '<': 1, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Comparison of the effects of intravenous magnesium sulphate versus intravenous aminophylline in acute attack of asthma in Pediatric Emergency Department, Lahore General Hospital, Lahore

In children acute severe asthma is a serious condition. The inhaled route for drug delivery is not appropriate when only small respiratory gas volumes are shifted; the i.v. route may be associated with greater side effects. Magnesium sulphate IV has a place in acute asthma management because it is a mild bronchodilator, and has a stabilizing effect on the atria. 
Objective: To compare the effectiveness of intravenous magnesium sulphate versus intravenous aminophylline in acute attack of asthma. 
Study Design: Randomized control trial. 
Setting: Emergency Department of pediatric 
Duration: April 2017 to October 2017.Material & Methods: 60 
cases were included in the study. They were randomly divided in two comparable groups. Children in group A ware treated with intravenous magnesium sulphate and group B with intravenous aminophylline. The efficacy of the drug was judged by the improvement in the sign observed like respiratory rate (less than 40 per minute), pulse rate(<100), oxygen saturation( above 90 %) assessed after the time period of three hours. 
Results: Effectiveness of intravenous magnesium sulphate in acute attack of asthma was found in 28 cases in Group A (93.33%) and in 22 cases in Group B (73.33%) with p-value 0.03. However, 6.67% cases (2 cases) in Group A and 26.67% cases (8 cases) in Group B did not show effectiveness. 
Conclusion: The clinical efficacy of intravenous magnesium sulphate in managing case of acute severe asthma was better when compared with intravenous aminophylline.