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Hypersensitivity reactions due to abacavir.


 Glaxo Wellcome reports that 2-3 percent of patients in their clinical trial of the nucleoside analog abacavir (1592) have a hypersensitivity to the drug. Patients experience fever, severe nausea, and a generalized rash, usually occurring an average of 11 days after treatment begins. Symptoms subside when the drug is discontinued and return immediately when the drug is restarted.
