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P11.03: Ultrasound features of ovarian carcinoma in patients with BRCA 1 or BRCA 2 mutation

Objectives The aim of this research was to systematically examine the placenta in congenital anomalies. Methods: The placental pathological section was examined in 217 cases with congenital fetal anomalies including 87 cases with congenital heart diseases, 41 cases facial abnormalities, genitourinary abnormalities, 62 cases with neurologic abnormalities. Results: Placental infarction or villus degeneration was observed in 4 cases and chorangiosis was found in 12 cases with congenital heart diseases corresponding to the overall placental disease rate being 16.1%; chorangiosis was observed in 5 cases with facial abnormalities corresponding to the placental disease rate being 12.1%; chorangiosis was found in 2 cases with genitourinary abnormalities corresponding to the placental disease rate being 7.4%. In addition, chorangiosis was observed in 10 cases with neurologic abnormalities corresponding to the placental disease rate being 14.5%. Conclusions: Relative to other system abnormalities the placental disease rate was more higher in cases with congenital fetal heart anomalies.