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The Epidemiology And Management Of Orbital Cellulitis

Background/Purpose: Orbital cellulitis is a rare but serious bacterial infection of the post-septal tissues of the eye that can lead to significant complications, such as permanent vision loss, meningitis, and intracranial abscesses. Following the introduction of the pneumococcal conjugate vaccine (PCV) and emergence of methicillin-resistant Staphylococcus aureus (MRSA) over the past decade, the epidemiology of this condition has likely evolved, necessitating re-evaluation of current antimicrobial management strategies. Furthermore, a lack of standardized management guidelines has led to significant heterogeneity in antibiotic selection, treatment duration, and surgical intervention. We investigated the largest US cohort of …