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Metachromasia of Fibroblasts From Patients With Idiopathic Scoliosis

Cells in fibroblast cultures from patients with idiopathic scoliosis were compared with cells from a control group without idiopathic scoliosis regarding the presence of metachromasia. Seventy percent of the cultures from patients with Idiopathic scoliosis demonstrated this characteristic, as compared with 30% of the control group (P < 0.005). Possible interpretation of these findings is discussed.