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Recombinant ZIKV envelope proteins for the arbovirosis differential diagnosis by ELISA

Introduction: The Zika virus is an arbovirus of the Flaviviridae family that causes asymptomatic and symptomatic infections. The clinical diagnosis of arboviroses is difficult in areas with cocirculation of these viruses and, therefore, laboratory confirmation based on host immune response is important, especially for pregnant women. The use of recombinant proteins as antigens aims to improve the sensitivity and specificity of the immunological test.