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Pathogen reduction of buffy coat platelet concentrates using riboflavin and light: comparisons with pathogen‐reduction technology‐treated apheresis platelet products

Background and Objectives  A pathogen‐reduction technology (PRT) system using riboflavin and light has been developed for the treatment of platelet concentrates (PC) obtained by either buffy coat preparation (BCPC) or apheresis procedures (APPC). The aim of this study was to evaluate the effects of the treatment process on in vitro cell quality and on riboflavin conversion in PC.