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[Efficacy of nasal spray-type allergen blocker combined with oral antihistamines in patients with dust mite allergic AR].

Objective:To investigate the clinical effect of nasal spray type allergen blocker combined with oral antihistamine on dust mite allergic allergic rhinitis (AR). Method:Ninety cases of patients withmild-severe allergic to dust mite were randomly divided into experimental group and control group, 45 cases in each group. The experimental group used nasal spray allergen barrier agent combined with citrate tablets, and the control group used physiological seawater combined with citrate sheet. The symptoms of subjective rhinitis, objective signs, improvement of quality of life scores and adverse reactionsof 2 groups were evaluated before and 2 weeks after treatment. Result:The symptoms, signs and quality of life of the patients in the experimental group were better than those in the control group (P<0.05). No obvious adverse reactions were observed. Conclusion:The effect of nasal spray type allergen blocker combined with antihistamine on AR patients with allergic to dust mite is remarkable. They can significantly alleviate the symptoms and signs of rhinitis in patients, and is worthy to be popularized in clinical application.