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Primary melanoma of the spinal cord: a case report, molecular footprint, and review of the literature.

Introduction Primary melanoma of the spinal cord is a rare entity with fewer than 60 cases reported in the literature since the first report in 1906. The diagnosis requires exclusion of a primary cutaneous or ocular lesion, as in rare instances melanoma may metastasize to the spinal cord. Prognosis is generally better, with a slower rate of progression, than for cutaneous melanoma with CNS metastases. We report a case of this uncommon tumor and also describe the molecular footprint that characterizes it.