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Risk of nontuberculous mycobacterial pulmonary disease with obstructive lung disease

Nontuberculous mycobacterial pulmonary disease (NTM-PD) is increasingly prevalent [1] and especially common in the elderly [2]. It is usually chronic, requiring complex therapy with suboptimal outcomes [3]. Risk factors for NTM-PD may be covert, presumably disordered mucociliary defences, or overt structural lung abnormalities. In one study, 56% of NTM-PD patients had unexplained nontuberculous mycobacteria (NTM) and among the rest with structural lung disease, chronic obstructive pulmonary disease (COPD) was the most common predisposing condition [4]. High incidence of NTM pulmonary disease in people with COPD and asthma (142 and 53 per 100 000 person-years) http://ow.ly/2laN300kLOV