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Transcession of DNA from Bacteria to Human Cells in Culture: A Possible Role in Oncogenesis

Abstract: The human organism is continuously in close contact with microorganisms, especially bacteria. In the present work, by means of a real‐time polymerase chain reaction (PCR) technique, we looked for the presence of a distinct bacterial gene in human cells. To this end, we cultured a human cell line, HL60, in a supernatant in which bacteria (Bacillus subtilis) had been grown. A transient transcession of bacterial DNA into the human cells was observed.