{'fraction_non_alphanumeric': 0.024875621890547265, 'fraction_numerical': 0.0, 'mean_word_length': 5.863636363636363, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Aldosterone and Salt Induces Hypertension Associated with Increased Oxidative Stress in the Brain of Apolipoprotein E Knockout Mice

Oxidative stress in brain plays a crucial role in the neural mechanism of hypertension. Apolipoprotein E‐knockout mice (apoEKO) reveal increased oxidative stress in the vasculature, heart, and kidney. Aldosterone (ALDO)‐salt load promotes hypertension and organ damage. We hypothesized that apoEKO was susceptible to ALDO‐salt thereby causing hypertension associated with the increased oxidative stress in the brain using an in vivo electron spin resonance (ESR) method.