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Prevalence of symptoms in the elderly with incurable cancer: a systematic review

Review questions/objective 
The overall aim of this systematic review will be to find and synthesise the best available evidence regarding the prevalence of symptoms in elderly persons with incurable cancer. The following questions will be addressed: 
1. Which symptoms do elderly people with incurable cancer experience? 
2. What is the point prevalence of the identified symptoms in the elderly with incurable cancer? 
3. Is there a difference in the prevalence of symptoms in different subgroups (subgroups such as, but not limited to, cancer stage and cancer type)? 
 
Inclusion criteria 
Type of participants 
This review will consider studies including adults older than 65 years and suffering from incurable cancer. All quantitative studies with reported data that are appropriate for the estimation of the prevalence of interest for this review will be included. Consideration will be given to ensuring the inclusion of studies with an appropriate sample size for the estimation of prevalence. 
Type of outcomes 
Studies reporting on the point prevalence of symptoms (physical, psychological, social, spiritual) or reporting a proportion or number of patients with the symptom will be considered for inclusion. In intervention studies in which symptoms are possibly affected by that intervention, only baseline measurements will be used.