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Transcriptome Analysis of the Response of Pseudomonas aeruginosa to Hydrogen Peroxide

ABSTRACT Pseudomonas aeruginosa must often overcome a high concentration of oxidants to successfully infect the human host. We report here the results of a transcriptome profiling comparing cells treated with H2O2 and untreated controls. The data indicate that the early response of P. aeruginosa to H2O2 consists of an upregulation of protective mechanisms and a downregulation of primary metabolism.