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Unexplained Systemic Hypertension after Closure of Ductus Arteriosus

I read with interest the case of systemic hypertension after surgical closure of patent ductus arteriosus (PDA) reported by Davierwala and colleagues.1 We encountered the same complication after transcatheter occlusion of PDA with a Rashkind umbrella. With this experience, we conducted a prospective study to evaluate the possible role of the potent vasoconstrictor angiotensin II (AT-II) in this complication.