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The Else Kröner‐Fresenius Award announced

The Else Kröner-Fresenius Immunology Award [1] was launched to acknowledge groundbreaking discoveries in medicine and to facilitate highly innovative and clinically relevant future research. This year’s award, commemorating the 25th anniversary of the death of the German pharmacist, entrepreneur and humanitarian, is the first of what will be quadrennial prizes to distinguish pioneering and promising research. On June 5th, 2013, in a ceremony at the German Historical Museum in Berlin, the inaugural prize was bestowed on Ruslan Medzhitov in recognition of his outstanding contributions to the understanding of the molecular mechanisms underlying innate immunity, and for his creative proposal of how to harness his research for innovative intervention measures for infectious and inflammatory diseases. Yale University Professor of Immunobiology and Howard Hughes Medical Institute Investigator since 2001, Medzhitov demonstrated that innate immune recognition is essential for the stimulation of adaptive immunity and elucidated the importance of recognition of symbiotic bacteria for the maintenance of physiological homeostasis. Beyond acknowledging Medzhitov’s achievements, the prize will also reward his future work to translate those accomplishments into health benefits. Indeed, Medzhitov and his group will seek to identify means to stimulate the most appropriate immune response for a given infection, with direct consequences for the rational design of tailor-made vaccines against infectious, inflammatory, and malignant diseases. Moreover, he will focus on the functional aspects of pathogen sensing, i.e., how the recognition of pathogen invasion via defined molecules is complemented by sensing of discrete harmful functions. This will lead to the development of means to control helminth infections and allergic responses, which are likely sensed via functions rather than molecules. Medzhitov was selected after a very thorough multistep process from out of 45 very promising nominations received from national immunology organisations belonging to the International Union of Immunological Societies (IUIS). An international jury of eminent immunologists, chaired by IUIS President and former President of EFIS, Stefan H.E. Kaufmann, evaluated all nominations. In addition to the above-mentioned ceremony in Berlin, Medzhitov will also deliver the Else Kröner-Fresenius Award Lecture this coming August 25th, 2013 during the 15th International Congress of Immunology in Milan (August 22–27, 2013).