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Headache, Thrombolytic Therapy, and Chronic Subdural Hemorrhage—A Case Report

Subdural hematomas are well known but infrequent complications of throm bolytic therapy. Although these are usually associated with head trauma, the authors describe a case of a patient who received a particularly aggressive thrombolytic regimen and presented six months later with complaints of noth ing more than a headache resistant to medical therapy, without associated neu rologic manifestations, which was finally diagnosed as a chronic subdural hematoma by computerized tomography. In the era of thrombolysis, physicians should maintain a heightened index of suspicion for subdural hematoma in pa tients complaining of headache.