{'fraction_non_alphanumeric': 0.03807615230460922, 'fraction_numerical': 0.01603206412825651, 'mean_word_length': 4.813953488372093, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Structural basis for antiviral activity of flavonoids-naturally occurring compounds.

The effect of different substituents of quercetin and luteolin on the ability to inhibit the herpes simplex virus (HSV-1) replication in RK-13 cells was studied. It seems that parent compounds with free hydroxyl groups at C-5, C-7, C-3', C-4' and additionally at C-3 have the highest activity. Substitution of those groups caused decrease of or completely abolished the antiviral activity of the tested compounds.