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[Combined echo- and Doppler echocardiography determination of diastolic function parameters of the left ventricle].

In patients with arterial hypertension with and without LVH and in hypertrophic non-obstructive cardiomyopathy diastolic parameters were analyzed with M-mode and Doppler-Echocardiography. In hypertrophied hearts we could demonstrate, that Doppler estimated transmitral flow during rapid filling phase was significantly reduced. The lower early diastolic flow is compensated by an augmentation of atrial systole (higher A/R quotient). Diastolic filling anomalies are the consequence of impaired ventricular relaxation due to myocardial hypertrophy as could been proven by the M-mode derived isovolumetric relaxation time and retraction constant Te. Doppler echo is a very good tool for characterization of diastolic function not only in hypertrophied hearts, but also in coronary artery disease. Moreover it is possible to assess the efficiency of coronary artery bypass grafting or pharmacological interventions.