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Transplantation of a kidney from a patient with idiopathic hypercalciuria.

CONTROVERSY exists concerning the nature of the defect in idiopathic hypercalciuria. Whether the hypercalciuria represents inability of the kidney to conserve calcium or is a manifestation of excessive gastrointestinal absorption of calcium has never been completely resolved. We recently had a unique opportunity to study this problem when a patient with idiopathic hypercalciuria donated a kidney to his son. Case Report The father had always been in excellent health except for an isolated episode of a renal stone at the age of 41. Random 24-hour urinary calcium determinations on an unrestricted diet were 400 to 500 mg. Physical examination was . . .