{'fraction_non_alphanumeric': 0.02857142857142857, 'fraction_numerical': 0.01904761904761905, 'mean_word_length': 5.264900662251655, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Expression of MMP-9 and relation between MMP-9 and proliferative activity in gastric carcinoma

Objective:To investigate the expression of matrix metalloproteinase 9 (MMP 9) in gastric cancer and to discuss the relation between MMP 9 and the proliferative activity of tumor cells.Methods:In 74 cases of gastric cancer,immunohistochemistry (S P method) was used to calculate the positive rate of MMP 9 and proliferative cell nuclear antigen labeling index (PLI).The clinical pathological parameters were analyzed at the same time.Results:In gastric cancer,the expression of MMP 9 was closely related to the depth of invasion,differentiation and metastasis of lymph nodes ( P 0 05).The stronger expression of MMP 9,the higher level of PLI ( P 0 01).Conclusion:The carcinoma cells with high proliferative activity have the strong tendency to secrete MMP 9 and MMP 9 plays an important role during the invasion and metastasis of gastric carcinoma. [