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Life course epidemiology and its implication for oral health.

These studies are designed to help the establishment of causal relationships between exposures and outcomes, taking into consideration the duration and the time of disease development. Chronic diseases have a long period of development, generating a mis-match between the exposure, the beginning of the disease and the first clinical signals. Oral health is an excellent area to study life course deter-minants of the diseases since the most impacting oral diseases and disor-ders are cumulative and chronic, present relatively high prevalence and are easy to be identified.