{'fraction_non_alphanumeric': 0.015873015873015872, 'fraction_numerical': 0.0031746031746031746, 'mean_word_length': 5.636842105263158, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Rescue Intravitreal Methotrexate Treatment Following Early Recognition of Proliferative Vitreoretinopathy.

Purpose
To report a case of proliferative vitreoretinopathy in a man with recurrent retinal detachment successfully managed without surgical intervention following initiation of intravitreal methotrexate injections to arrest progression of PVR.


Methods
Report of a case.


Results
A 60-year-old man presented to the retina clinic 4 weeks after undergoing vitrectomy for rhegmatogenous retinal detachment and was found to have an inferior recurrent retinal detachment. He underwent repeat vitrectomy and scleral buckling with successful re-attachment of the retina in the immediate post-operative period. At post-operative week 2, pre-retinal membranes were noted inferiorly with stretching of the causative retinal break and localized subretinal fluid, consistent with early PVR. The patient underwent immediate laser barricade, and a course of intravitreal methotrexate injections was commenced. At final follow-up seven months later, the retina was fully attached without progression of PVR.


Conclusion
Intravitreal methotrexate may play a role in arresting progression of early postoperative PVR and obviating the need for surgical intervention.