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Allele frequencies of Mp6D‐9 and GATT markers in 32 Turkish cystic fibrosis families

The allele frequency of GATT and Mp6D‐9 markers was investigated in 32 cystic fibrosis (CF) families. The GATT6 allele was found to be significantly associated with the ΔF508 mutation. The Mp6D‐9 allele 2/GATT6 haplotype was the major haplotype of the mutant alleles. Further analysis of CF alleles for population‐specific mutations is underway so that a more direct approach can be taken, especially for families seeking prenatal diagnosis.