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Chemistry of Small Spaces

Abstract The fundamental science of materials and life, which has greatly contributed to humanity, lies in atoms and molecules. For two centuries, chemistry focused on synthesizing molecules or “skeletons assembled from atoms.” This approach led to the development of various substances (pharmaceuticals, foods, dyes, pesticides, clothes, plastics, etc.). In the late 20th century, this concept evolved into supramolecular chemistry, where molecules were used as constituents and eventually led to the nanoscience field.