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[Experimental and clinical observation on wrinkle correction by medical cosmetic collagen injection].

Medical cosmetic collagen is a new biomaterial for soft tissue augmentation, such as wrinkle correction, It consists of highly purified human collagen. The ratio of type I and type III collagen is 44/56. The persistence of collagen in rats is more than one year. Rat cells and capillaries grew into the injections. Fibroblasts synthesized rat collagen. Capillaries established blood supply. The clinical observation on 123 cases proved the safety of this product. No adverse reactions developing from the use of the collagen were found. It was effective in correcting contour deformities of the skin. More than 90% correction results were excellent or good.