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Antibiotics for uncomplicated severe malnutrition.

Trehan et al. also show that the risk of death in this population continues beyond the initial week of therapy, suggesting that longer-term solutions are needed. Given the environment in which these children live, we suspect that they are frequently exposed to contaminated drinking water. The incidence of diarrhea and pneumonia, diseases that the authors speculate were modulated by antibiotics, can be reduced by good hand-washing practices and the treatment of drinking water by 31% and 21%, respectively —or more.2,3