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Assessment of clinical profile of patients with thrombocytopenia

Background: Thrombocytopenia is characterized as platelet tally less than 1,50,000/μL. This is because of diminished creation, expanded obliteration, and expanded sequestration in spleen. The present study was conducted to assess clinical profile of patients with thrombocytopenia.Materials & Methods: 94 patients of fever with thrombocytopenia of both genders were included. In patients with bleeding complications, platelet transfusions were done if platelet count was <20,000/μL. Etiologic and clinical data of all the patients was recorded.Results: Out of 94 patients, males were 50 and females were 44. Etiology was malaria in 19, viral fever in 33, dengue fever in 25, scrub typhus in 11 and septicaemia in 6 cases. Clinical symptoms were cough seen in 30, fever in 94, headache in 57, pallor in 35, chills & rigors in 38, rashes in 56, jaundice in 15 and bleeding in 2 patients. In fifty seven percent of the cases, platelet count was between 100000 to 150000 per cubic mm.Conclusion: Infectious diseases accounts for most of the cases of febrile thrombocytopenia. Most common cause was malaria, viral fever , dengue fever, scrub typhus, septicaemia and leptospirosis.