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Critical Perspectives on Time-Varying Models for BOLD Functional Connectivity

Tuesday, Jun 19: 2:45 PM 4:00 PM 3552 Symposium Tuesday Symposia PM In recent years, "dynamic" functional connectivity or functional connectivity that changes with time has become an emerging area of investigation in fMRI. However, other types of time-varying models of functional connectivity are also possible where the time-varying parameters are not functional connectivity but rather other second-order statistics of the BOLD signal such as the autocorrelation or the signal variance. For example, there is a growing interest in "temporal networks" that capture dependencies between individual time-points during rest or task-fMRI. Moreover, multiple and distinct time-varying models may fit the same fMRI data equally well. Consequently, it is unclear whether the time-varying aspects of the inferred models have neurobiological significance.