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Extragastrointestinal stromal tumour arising in the vulva: a case report and literature review

Gastrointestinal stromal tumour (GIST) is the most common mesenchymal neoplasm of the gastrointestinal (GI) tract. Although the majority of GISTs arise in the stomach and small bowel, they may occur anywhere in the GI tract. Rare cases of GISTs outside the GI tract, called extragastrointestinal stromal tumours (EGISTs), have also been described. EGISTs have pathological features similar to those of GISTs. Although EGISTs have been often reported in the omentum, retroperitoneum, and mesentery, they rarely arise from the vulva. Only two cases of primary EGISTs of the vulva have been reported to-date. Here, we report our experience of a 51year-old woman with an EGIST of the vulva, and shortly review the literature.