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Fine structure of the Leydig cell during postnatal differentiation of the mouse testis

It is possible to divide the ultrastructural events which take place in the mouse Leydig cell during postnatal differentiation into two periods. The first period includes the changes taking place during the first three weeks after birth, whereas the second period comprises the events occurring from the fourth week on. During the first period the cytoplasm contains a poorly developed smooth endoplasmic reticulum. After the tenth day a slight increase in the number of vesicles and tubules of the smooth endoplasmic reticulum is observed. Clusters of glycogen particles (beta type) and lipid droplets are very numerous in this period.