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T/NK-cell post-transplant lymphoproliferative disorder of the urinary bladder: a case report

Post-transplant complications including neoplastic disorders such as carcinoma and lymphomas, related primarily to chronic immunosuppression, are well recognised.1 Post-transplant lymphoproliferative disorders (PTLDs) are a group of lymphoid or plasmacytic proliferations that develop as a consequence of immunosuppression after receipt of a solid organ, bone marrow or stem cell allograft and for which there is no other known explanation.2 3

A young person underwent a successful renal transplant for end-stage renal failure in 1995 in a different hospital. His post-transplant medications included ciclosporin (stopped in 1997), azathioprine and prednisolone. This patient presented to us 14 years later with intermittent painless haematuria. CT scan revealed a large bulky, heterogeneous mass measuring 8×9×5.6 cm in the posteroinferior wall of the bladder …