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P12.05: The characteristics of congenital heart disease in twin pregnancy

first trimester. We aimed at describing key features of tetralogy of fallot (TOF) on real-time volumetric 3D reconstruction of fetal heart anatomy and Doppler angiography of great vessels at first trimester scan. Methods: In our center, second line ultrasound examinations of fetal heart is routinely offered at first trimester in all patients with a NT measurement > 99th centile. In cases with a diagnosis of TOF 3D volumes were retrospectively reviewed in order to define key features of this defect at first trimester. Results: During the study period, 3 cases of TOF was suspected and later confirmed. Fetal karyotype was performed allowing for the diagnosis of aneuploidy in all 3 cases. TOP was performed according to parents decision and local laws and pathological examination confirmed the diagnosis all 3 cases. 3 D volumes analysis allowed to pick up two major findings as early as first trimester. The axis of the heart which is in a left lateral deviation and abnormal three vessels view with a large aortic root and a small pulmonary artery. Conclusions: Our findings suggest that TOF might be suspected as early as first trimester in the presence of a left lateral deviation and abnormal three vessels view showing a large aortic root and a small pulmonary artery. Although these early cases seem to carry a very poor prognosis, sonographer should not overlook those signs, particularly when scanning fetuses with increased NT.