{'fraction_non_alphanumeric': 0.030017152658662092, 'fraction_numerical': 0.04288164665523156, 'mean_word_length': 4.893939393939394, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Polymorphism RS2227306 In The Interleukin 8 Gene and Its Relation to Bronchial Asthma: Review Article

Background: Allergy symptoms such as wheezing, breathlessness, and coughing are all symptoms of asthma, which is a long-term respiratory condition characterized by inflammation and reversible airway blockage. If you're a child or young adult, asthma is the most common long-term condition, with more severe symptoms. The CXC chemokine superfamily includes the Interleukin 8 (IL-8) chemokine. T lymphocytes, neutrophils, and mast cells are all chemotactic cytokines that IL-8 attracts in the body. A polymorphism in the promoter region of IL-8 781C/T (rs2227306) has been found to be associated with an elevated level of the cytokine IL-8. There is a gene in the first intron of the IL-8 781C/T (rs2227306) that has been reported to aid in both gene transcription and gene regulation. Objective: The aim of the present review was to study polymorphism RS2227306 in the interleukin 8 gene and its relation to bronchial asthma. Conclusion: IL8 polymorphism rs2227306 has the potential to be utilized as a marker in interpretation of assessment of severity of asthma.