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APOE, thought disorder, and SPARE‐AD predict cognitive decline in established Parkinson's disease

People with PD are at high risk of developing cognitive impairment and dementia. Cross‐sectional studies have identified candidate biomarkers associated with cognitive decline. However, longitudinal studies on this topic are rarer, and few have investigated the use of biomarker panels encompassing multiple modalities. The objective of this study was to find baseline predictors of cognitive decline in longitudinally followed, nondemented Parkinson's disease patients.