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[Morphological characteristics of secondary pulmonary hypertension in liver cirrhosis].

Morphological examinations of 24 autopsy cases of liver cirrhosis demonstrated the development of secondary postcapillary pulmonary hypertension with an increase of the muscular mass of the right ventricle and rearrangement of the blood vessels of pulmonary circulation. Most important morphological changes were observed in intraorgan veins and microcirculatory bed of the visceral pleura (particularly in the venular knee) indicating early reaction of the veins to hemodynamic disorders. It is suggested that hypervolemia in the pulmonary circulation system developing at the expence of blood discharge from the portal system into direct portopulmonary anastomoses plays an important role in the genesis of pulmonary hypertension in patients with hepatic cirrhosis.