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Contagious and other aspects of nocardiosis in the compromised host.

Nocardiosis in the compromised host may be successfully treated if the diagnosis is made early while the infection is localized. The diagnosis is made by cultural isolation of the organism from the granulomatous lesions or infected secretions. Prolonged treatment with sulfonamides for up to four months or longer 16 is the treatment of choice. The temporal relationship of contact among three patients in this series suggests, for the first time, the possibility of man to man transmission.