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Tractable Model of Malignant Gliomas Immunotherapy with Discrete Time Delays

The model of an immune system reaction against malignant gliomas proposed by Kronik and co-workers is simplified to the main components of the immune reaction, which are tumor cells and cytotoxic T-lymphocytes. The system has nonlinear terms with three delays, but remains tractable. For realistic parameters, time delays have little influence on the dynamics.