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The Relationship between Symmetry and Specific Properties of Supramolecular Systems

Released agent is a supramolecular system formed around nanobubbles in highly diluted solutions of substances subjected to technological processing. Released agent retains the structure and symmetry of the supramolecular system of the dissolved substance. It has two specific properties: (1) when combined with the original substance, it modifies its effect on an organism; (2) and it could cause an atypical pathological reaction in some individuals. These properties could be due to the transmission of symmetry from released agent to the receptor in the molecular recognition reaction by deforming the receptor structure. A theoretical analysis of these properties was carried out using methods of statistical thermodynamics of complex systems, chemical thermodynamics of supramolecular systems, and analytical mechanics. The released agent’s modifying effect is a phenomenon of the receptor pre-organization in the molecular recognition reaction. The selective ability and free energy of complex formation of released agent (from highly diluted antibodies to the beta-subunit of the insulin receptor) with the insulin receptor was evaluated. The atypical pathological reaction of some individuals to released agents resembles a resonance phenomenon that occurs when the symmetries (structures) of released agent and the receptor coincide. The obtained results show a possibility to investigate released agents’ properties not only empirically, but also using the methods of theoretical physics.