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The Adaptive Response of Rectal Electrolyte Absorption to Impaired Sodium Balance in Young Children

Rectal electrolyte transport was measured in nine children (median age 160 days) with ilcostomies, using a nonequilibrium dialysis technique. Rectal sodium absorption and potassium secretion were significantly higher in children with a subnormal sodium balance compared with children with a positive sodium balance. Rectal sodium absorption and potassium secretion were unchanged after ileostomy closure. These data indicate that rectal electrolyte transport in children can adapt to even modestly impaired sodium balance.