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Posttraumatic hypopituitarism: anterior pituitary insufficiency secondary to head trauma.

A 30-year-old woman, who was involved in an automobile accident two years before admission, presented with hypopituitarism. Deficits of ACTH, FSH, LH, GH, and borderline TSH were demonstrated. Normal TRF response and elevated prolactin levels indicated residual normal anterior pituitary tissue with inadequate hypothalamic control. We have briefly reviewed the subject of posttraumatic hypopituitarism.