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Polymorphic Alu insertions in five North‐West Italian populations

We analyzed the frequencies of eight human polymorphic Alu insertion loci in population samples from five towns in North‐West Italy: Postua, Cavaglià, Biella, Torino, and Genova. All loci under scrutiny were found to be polymorphic in all samples, with the two exceptions of locus A25 in Postua, which was fixed for the absence of the Alu element, and APO in Genova, where the Alu insertion was fixed. Heterozigosity values were highly variable in all loci. FST values for all loci indicate that most of the variability is found within populations, while between population variability is lower. In the multidimensional scaling (MDS) analysis plot, the studied populations are separated from the main group represented by European populations. The Postua sample is set apart also from neighboring towns as Cavaglià and Biella, confirming previous observations of the demographic isolation of this population. Am. J. Hum. Biol. 19:589–592, 2007. © 2007 Wiley‐Liss, Inc.