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[Study of cyclic AMP in rat tissue during the phase of hypocalcemic activity of parathyroid hormone].

As soon as two minutes after PTH i.v. injection the blood and kidney AMPc level is maximally increased but the lowering blood calcium effect remained till to ten minutes. At this time the calvaria AMPc level reached its maximum just at the onset of hypercalcemic effect of PTH. Thus AMPc increase in tissues is consistent with the two opposite effects of PTH.