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Homeostasis model assessment of insulin resistance in response to aerobic program in adult obese women

Physical activity is widely accepted that improve glucose homeostasis and insulin resistance in obese patient populations. This study was aimed to investigate the effect of a long term aerobic training on glucose profile and insulin action in obese women. For this purpose, pre and post aerobic training (3 per week / 12 weeks) blood samples were collected in fifteen adult obese women and compared with control group (no training) matched for age, gender, height, and BMI. Student’s t-tests for paired samples were performed to determine whether there were significant within-group changes in the outcomes. A p-value less than 0.05 were considered statistically significant. At baseline there were no differences in the biochemical variables and anthropometrical parameters between the two groups. There was a decrease in fasting glucose levels and anthropometrical markers after exercise intervention. Compared to pre-training, serum insulin and insulin resistance decreased significantly after exercise program but not in the control group. Our results indicate that aerobic training for long time improves glucose homeostasis in obese men that is associated with improved insulin resistance. * Corresponding Author: Zahedmanesh Forouzan  foruzanzahedmanesh@yahoo.com