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Approaches to detection of airborne biological agents

Three approaches to detection of biological agents based on biological processes will be presented. The first example demonstrates the use of dendrimers to deliver a membrane-impermeable fluorescent dye into live bacteria, similar to viral infection and delivery of DNA/RNA into a bacterial cell. The second example mimics collection and capture of airborne biological particles by the respiratory mucosa through the use of a hygroscopic sensing membrane. The third example is based on the use of multiple fluorescent probes with diverse functionalities to detect airborne biological agents in a manner similar to the olfactory receptors in the nasal tract.