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[Secondary osteoporosis or secondary contributors to bone loss in fracture. Regulation of bone homeostasis by nerve system].

The identification that nervous system controls bone metabolism through leptin knock out mice studies opened a new field in bone biology. Notably, sympathetic and parasympathetic nervous system regulate bone formation and bone resorption. In addition, sensory nervous system also has been shown to be involved in the regulation of bone homeostasis. These studies demonstrated that nervous system is closely related to bone remodeling.