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Treatment of warts with Candida antigen injection.

Background: A safe, simple, effective method of treating warts is needed. Objectives: To evaluate 1) safety of candida antigen injections for the treatment of common warts, 2) patient satisfaction with the treatment. Methods: Chart review and telephone follow-up of 149 patients treated for common warts by intradermal and intralesional candida antigen injections. Results: 104 were reached by telephone for follow up Side effects: 54 patients (52%) mild, local reactions, no severe reactions. Satisfaction: 79 patients (76%) "very happy", 10 (10%) "happy", 13 (12%) "unhappy" and 2 (2%) "very unhappy". 85 patients (82%) would repeat the treatment if needed. Resolution of warts: 73 patients (70%) had complete cure within 8 weeks of the last injection. Conclusion: Candida antigen injection for the treatment of common warts is safe and well accepted by patients. A randomized controlled trial will be required to conclusively prove efficacy for this treatment.