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EFFECTS OF INTRAPERITONEAL BUPIVACAINE VERSUS PLACEBO ON POSTOPERATIVE PAIN AFTER LAPAROSCOPIC CHOLECYSTECTOMY: A RANDOMISED DOUBLE BLIND STUDY

Background & Aims: Postoperative abdominal and visceral pain after elective Laparoscopic Cholecystectomy (LC) is of prime concern to
patients as it causes signicant distress. (1)(2) The aim of our study was to evaluate the benet of intraperitoneal bupivacaine irrigation on the
surgical bed versus placebo.
Methods: 50 patients undergoing elective laparoscopic cholecystectomy were included in the study. They were prospectively randomised into 2
groups. The placebo group (Group P, n = 25) received 35 cc saline without bupivacaine, installed into the gallbladder bed. The bupivacaine group
(Group B, n =25) were given 35 cc of 0.25% bupivacaine at the same location. Pain was evaluated at regular intervals of 0, 5, 10, and 24 hours using
the visual analogue scale (VAS).
Result: Asignicant difference (P=) was seen on VAS to evaluate post-operative pain between two groups at 5 hours post operatively.
Conclusion: Irrigation of local anaesthetic bupivacaine at the gall bladder bed can be an effective method for decreasing post-operative pain in the
rst 5 hours after laparoscopic surgery.