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Dementia in hypopituitarism

Sirs, Patients with hypopituitarism present a combination of corticosteroid, thyroid, growth and sexual hormones deficits, and they can experience many physical and cognitive symptoms. The cognitive impairment that corticosteroids and thyroid hormones disturbances can cause is well known, but not completely understood, whereas it seems that gonadotropins and growth hormone do not play an important role in adults mental function. Hypopituitarism with secondary hypocorticism is a rarely reported cause of dementia commonly with atypical features. Here, we review the literature and present a case of reversible dementia secondary to hypocorticism.