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Absorption of folic acid and ascorbic acid from beverages

The purpose of this study was to test for possible differences in the bioavailability of nutrients from three different beverages using a double‐blind, within‐subjects experimental design. The study tested whether the bioavailability of vitamin C (i.e. ascorbic acid or AA) and folic acid (FA) in adult men differed after ingestion of a fortified beverage (Essential VitaminWater, Glacêau®), orange juice (OJ) and 1% milk. Participants were aged 20‐35y, with body mass indexes ranging from 20‐30 kg/m2. Serum concentrations of AA and FA were assayed by serial blood draws, which were made at 30 min intervals for 4.5 hours. Results showed that the concentration profile of AA was significantly greater after ingestion of the fortified beverage compared to OJ. However, the bioavailability of AA in the fortified beverage and OJ was not significantly different, indicating that the higher serum concentration of AA in response to the fortified beverage was due to that beverage's higher AA concentration. In terms of FA, analyses indicated that serum concentration and bioavailability did not significantly differ between the fortified beverage and OJ. Research support provided by Glaceau LLC.