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The Use of Propolis in Micro/Nanostructured Pharmaceutical Formulations.

BACKGROUND
Propolis is a resinous material with complex chemical structure, produced by bees using plant sources, displaying a wide spectrum of biological activities.


METHODS
Many studies have reported the use of this compound in pharmaceutical, medicinal, veterinary and dentistry areas, and the results have reported its pharmacological activities.


RESULTS
Moreover, many propolis delivery systems have been proposed and evaluated, indicating that they can be used. On the other hand, considering its chemical and physical characteristics, propolis could be used as a material to produce micro/nano-structured pharmaceutical formulations.


CONCLUSION
This work reviews the recent studies of development of micro/nanostructured systems using propolis or its byproduct. In addition, patents were reviewed and categorized.