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Endogenous endophthalmitis caused by Aspergillus flavus in an immunocompetent individual – A rare case with review of literature

There are very few reports of Aspergillus flavus causing endogenous Aspergillus endophthalmitis (EAE) in immunocompetent individuals although it is well recognized in the immunocompromised. Treatment can be with intravitreal, intravenous and oral antifungal agents. We present a case of EAE in a 23-year-old female with no predisposing risk factors. A detailed systemic evaluation failed to reveal any systemic focus or predisposing factor for fungal infection. The patient had received an intravenous dextrose infusion two days before this episode while being treated at a rural hospital for fever. She presented with a sudden loss of vision and was subsequently managed with intravitreal voriconazole therapy. This case adds to the limited literature on the prevalence of endogenous endophthalmitis in immunocompetent patients and supports the use of voriconazole in such cases.