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Mycosis fungoides – analysis of the duration of disease stages in patients who progress and the time point of high‐grade transformation

Background  Mycosis fungoides (MF) is a low‐grade malignant primary cutaneous T‐cell lymphoma which, in its evolution, passes through five distinct stages (patch, plaque, and tumor stages, lymph node infiltration, and, finally, multiple organ infiltration). Furthermore, a blast transformation into a high‐grade malignant lymphoma can occur. In order to better understand the dynamics of the disease and the prognostic implications in patients who progress, we studied the duration of each stage and the time at which blast transformation occurred.