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Rn:Ra ratios in bone of beagles injected with 226Ra.

AN IMPORTANT component of the equation for estimating skeletal radiation dose to an animal or human contaminated with 226Ra is the fraction of 222Rn produced by Ra decay in bone that is retained in bone to undergo further radioactive transformation. For young adult beagles, the contribution to the total skeletal dose from Ra and its progeny accounted for by Rn and its retained progeny is more than 50% (Lloyd et al. 1986). Earlier publications from this laboratory have reported the skeletal retention of Rn in our beagles injected with Ra as young adults about I .5 y of age (Mays et al. 1975 ) or as juveniles about 3 mo old (Lloyd et al. 1983). The retention in each experiment was found to be a function of time after injection, but the function was discontinuous between the two ages of dogs. More recently, we had the opportunity to determine the Rn:Ra ratios in beagles injected with 226Ra at ages intermediate between 3 mo and 1.5 y and to resolve the discontinuity between the two equations.