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Diagnosis of alveolar rhabdomyosarcoma in effusion cytology: a diagnostic pitfall

Rhabdomyosarcoma (RMS) is a rare malignancy in adults, accounting for less than 5% of soft tissue sarcomas in this age group. Sarcomas account for approximately 5% of malignant effusions. Expression of neuroendocrine and epithelial markers by alveolar RMS has been demonstrated recently, highlighting a diagnostic pitfall in effusion cytology, especially when dealing with small, round cell tumours (SRCT).