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Desipramine and imipramine overdose in a psychotic adolescent.

Abstract Toxic desipramine ingestion is reviewed in light of the growing use of desipramine in children and adolescents. A 14-year-old boy who took an overdose of desipramine and imipramine in an attempt to kill himself is presented. The case is discussed in the context of adverse cardiovascular and central nervous system effects and deficiencies in the provision of care that increase the risk of self-endangering behavior.