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[Genetic polymorphisms of six Y chromosome short tandem repeat loci in Chinese Korean ethnic group].

OBJECTIVE
To determine the allelic sequences and genetic polymorphism of six short tandem repeats (STRs) loci on Y chromosome, including DYS441, DYS442, DYS443, DYS444, DYS445 and DYS446 in Chinese Korean ethnic males from Yanbian region of Jilin province, China, and to construct a preliminary database.


METHODS
Allele frequencies of the six STR loci in 205 Chinese Korean ethnic individuals were analyzed by multiplex polymerase chain reaction (PCR) and polyacrylamide gel electrophoresis (PAGE).


RESULTS
Respectively, 8, 7, 7, 5, 6 and 9 alleles were detected for each of the locus. Together they have formed 151 haplotypes, with a diversity of 0.9937.


CONCLUSION
The six STR loci included in this study were found to be highly polymorphic, and may provide useful markers for genetic analysis.