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Antibodies that Define NANA‐Independent MN‐System Antigens

The hemagglutinating properties of a large proportion of anti‐M and anti‐N reagents, and sera containing antibodies to MN‐related antigens, have been shown to be unaffected by treatment of red blood cells with neuraminidase. These antibodies, which define NANA‐independent MN‐ system structures, provide further evidence that MN blood group specificity may also be determined by moieties other than N‐ acetylneuraminic acid.