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Osteocalcin as a biochemical marker of bone turnover

SUMMARY: Osteocalcin is a calcium‐binding bone protein whose blood concentrations are correlated with bone synthesis and resorption. the level of blood osteocalcin is determined by several factors. Laboratory monitoring of blood osteocalcin is helpful in patient diagnosis and managment. This study presents the known biosynthesis of osteocalcin and its role as an index of bone turnover.