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Effect of Ramadan Fasting on Serum Glucose and Lipid Profile Among Algerian Type 2 Diabetes Patients

Abstract Background and aims: We designed this study to assess the effect of Ramadan fasting on serum lipid profile among type 2 diabetic patients. Material and Methods: The study was carried out in July 2014 (Ramadan 1421). The total duration of fasting was 17 hours a day. The investigation involved 80 patients. The mean age of the patients was 56± 8 years. The dietary survey lasting three days was recorded. The anthropometric and the biochemical parameters were measured in all subjects before (T1) and during (T2) the fasting month of Ramadan and results were compared using student t-test. Results: There was a significant decrease in high density lipoprotein cholesterol (HDL-c) levels during T2 (0.35±0,08 g/L) compared to T1 (0.38±0,11 g/L). Apolipoprotein A1 (Apo A1) decreased significantly during fasting compared to pre-fasting days while apo B increased during T2 (p˂0.05). The dietary fat consumption increased during Ramadan; especially for the saturated one (p<0.05). Conclusion: The present study suggests that fasting month of Ramadan could be beneficial for some patients with type 2 diabetes who are well controlled and balanced. However, some of them may be at risk of cardiovascular complications in which dyslipidemia can be the leading cause.