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Adenosquamous Carcinoma of Gall bladder : A Case Report And Review of Literature

Background- The Adenosquamous Carcinoma is  recognized as a rare histological subtypes of Adenocarcinoma of Gallbladder, where  squamous component of tumor constituted 25-99% of tumor . The incidence of Adenosquamous Carcinoma is approximately 5% of Gallbladder malignancy. The overall five year survival rate of Adenosquamous Carcinoma is less than 5% with a median survival of less than  6 months ( worser than Adenocarcinoma of Gallbladder). Adenosquamous Carcinoma have aggressive biological behavior due to their potential for direct extension into the Liver and neighbouring structures. Case Report- We present here a rare case of Adenosquamous Carcinoma  of  Gallbladder Stage IV in a 64-year-old woman who presented with right upper abdominal pain and Patient was diagnosed as Gallbladder perforation with cholecystocolic fistula. Cholecystectomy with Right hemicolectomy was performed and specimen of Gallbladder, Intestine and appendix was received in our Department of Pathology Dr S N Medical college Jodhpur  for Histopathological examination. Conclusion- Adenosquamous carcinoma is a rare malignant tumor having aggressive biological behaviour. Reporting this rare malignant tumor ads to the literature and helps in better understanding the biological nature and pathological characteristics of this rare tumor.