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Transfer-learning for differentiating epileptic patients who respond to treatment based on chronic ambulatory ECoG data

The aim of this study was to evaluate whether transfer-learning with pre-trained deep convolutional neural networks (deep CNNs) can be used for assessing patient outcomes in epilepsy. Transfer-learning with the GoogLeNet InceptionV3 CNN model pre-trained on the large ImageNet dataset (~1.2 million images) was able to differentiate upper (n=12) and lower (n=9) response quartile mesiotemporal lobe epilepsy patients in the NeuroPace® RNS® System clinical trials with ~76% classification accuracy based on chronic ambulatory baseline electrocorticographic (ECoG) data. These promising findings justify further research using deep CNNs for assessing patient outcomes in epilepsy.