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History of Dialysis Quantitation

The history of many disciplines is fragmented and often subjective, but the history of dialysis quantitation is held together by the contributions of Frank Gotch. The story is unfolded in Frank’s many publications and unpublished memoranda, including personal correspondence, some of which has graciously shared with me over the past 20 years. Frank Gotch is so interwoven into the history of dialysis quantitation that simply reading his papers provides more than half of the story. In fact he actually wrote a short history of dialysis solute kinetics, documenting historical milestones up to 1986 (1). The final chapter in this history is not yet written and will probably not appear for many years to come. Meanwhile, Frank Gotch continues to be a part of it, serving as a consultant to the HEMO Study. In recent years, those who have had an opportunity to see a bit beyond the fringes of established knowledge in this field have done so only from the shoulders of dedicated investigators like Frank Gotch.