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New genetic approaches: establishing resources for research

THE NATIONAL HEART, Lung, and Blood Institute (NHLBI) is committed to a broad-ranging program of research that builds on past achievements and capitalizes on the most promising new approaches and technologies. Molecular genetics constitutes an area of particular interest, because it has the potential to directly enhance our mastery over cardiovascular, lung, and blood diseases. Moreover, an understanding of the molecular genetics of disease will provide vital new information that can expand the considerable knowledge base from more traditional disciplines. To guide its efforts in this emerging area, the institute called upon an Expert Panel on Genetic Strategies for Heart, Lung, and Blood Diseases to formulate a master plan of major research opportunities and strategies for their implementation. This column highlights the development of two major initiatives recommended in the master plan: the “Mammalian Genotyping Service’’ and the “Genetic Map and Large Insert Library for the Rat Genome.”