{'fraction_non_alphanumeric': 0.017738359201773836, 'fraction_numerical': 0.0, 'mean_word_length': 5.7894736842105265, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Polyphenols prevent ageing‐related impairment in skeletal muscle mitochondrial function through decreased reactive oxygen species production

•  What is the central question of this study? Ageing impairs muscle function, which is a strong predictor of falls, hospital admission and mortality. Mitochondrial impairment and oxidative stress play a key role in this process. Polyphenols modulate oxidative stress, but whether they might protect muscles against ageing is unknown. •  What is the main finding and its importance? For the first time, this study demonstrated that intake of polyphenols starting at a young age totally restored muscle maximal mitochondrial oxidative capacity, normalized production of reactive oxygen species and enhanced antioxidant defence, therefore protecting aged muscle. This might open new therapeutic perspective for maintaining healthy muscle function in aged humans.