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Significance of exercise‐induced ST changes in leads AVR, V5, and V1. Discrimination of patients with single‐ or multivessel coronary artery disease

Background: It is known that exercise‐induced ST‐segment elevation in lead V1 (V1‐E) detects left anterior descending (LAD) stenosis. It was also postulated that ST elevation in aVR and simultaneous ST depression in V5 (aVR‐E + V5‐D) is a marker of ischemia due to significant stenosis of the LAD in patients with single‐vessel disease.