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Women with moderate‐to‐severe psoriasis in Spain (BIOBADADERM registry) show more than a 50% reduction in age‐adjusted fertility rate when compared with the general population

Previous studies based on claim databases have described a slightly decreased pregnancy rate in women with psoriasis. Cather et al. described that women with psoriasis have a 3·1% pregnancy incidence vs 3·6% for non-psoriatic women in the USA. This difference was affected by age, and was more pronounced in the younger group1 . Seeger et al. described the incidence and outcomes of pregnancy in women with inflammatory skin diseases (psoriasis, atopic dermatitis and other inflammatory skin disorders) in USA using data from health insurance claims. They did not find any strong association between the incidence of pregnancy and the diagnosis. However, within each skin disease group, they found a slightly lower pregnancy incidence in patients with more severe disease2 . Both studies had limitations: they used routine data, with imprecise measures of exposure and outcome. Other limitations were that they did not describe the characteristics of women who got pregnant that might indicate risk factors for altered fertility. Besides that, as the study had been done in the USA, and the results regarding fertility have a social component, they might not apply to other areas. This article is protected by copyright. All rights reserved.