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Bronchoalveolar lavage cells from sarcoidosis patients and healthy controls can efficiently present antigens

Objectives. The interaction between antigen‐presenting cells (APC) and T lymphocytes, that recognize the antigen‐HLA complex using its T cell‐receptor for antigen, is of crucial importance for a subsequent specific immune response. In patients with pulmonary sarcoidosis, the local antigen‐ presenting capacity in the lungs has been suggested to be abnormally enhanced, and implicated in the immunopathogenesis of the disease. This study was aimed at increasing the understanding of the capacity to present antigens by APC in the lung compartment.