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Aetiology and clinical features of severe infantile diarrhoea in Addis Ababa, Ethiopia.

The purpose of this study was to identify the etiology of diarrhea in children admitted for intravenous rehydration therapy and if possible correlate etiology with clinical features. 175 children were admitted during the study period (March through June 1979). They were compared to 74 age and sex matched controls. Histories were obtained and clinical appearances of patients and stools recorded. Stool samples were analyzed by microscopy and cultured. Microbial diagnoses were established in 70% of patients with the most common being rotavirus (49%) enteropathogenic E.coli (19%) and Campylobacter (13%). Intestinal pathogens were found in 13% of controls. An attempt was made to relate quality of stools duration of diarrhea rectal temperature and severity of dehydration to etiology but no significant relationships were detected.