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Therapeutic transfusions of granulocytes collected by simple bag method for children with cancer and neutropenic infections: results of a single‐centre pilot study

Background and Objectives  Granulocyte transfusion therapy (GTX) can be effective for life‐threatening infections unresponsive to conventional antimicrobial therapies in severely neutropenic children with cancer. We developed a new granulocyte collection method, named the ‘bag method’, in which apheresis, hydroxyethyl starch (HES) or dexamethasone are not used. We undertook a pilot study to determine the feasibility and the safety of GTX collected by the bag method for children with cancer and life‐threatening infections.