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Serotonin transporter promoter polymorphism and differences in alcohol consumption behaviour in a college student population.

AIMS AND METHODS
In the present study, differences in alcohol consumption behaviour associated with the presence of the short variant (S) of the serotonin transporter promoter polymorphism (5-HTTLPR) was investigated in a Caucasian subset (n = 204) of 268 college students.


RESULTS
Students who were homozygous for the S allele were more likely to engage in binge-drinking behaviour, drank more alcohol per occasion, and reported drinking to get drunk more often.


CONCLUSIONS
In this Caucasian sample, the 5-HTTLPR strongly influences alcohol consumption in late pubescence.