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Mesenchymal Stem Cells (MSC) Decrease Tubulointerstitial Injury and Improve Renal Function After Revascularization in Swine Atherosclerotic Renal Artery Stenosis (RAS)

Percutaneous transluminal renal angioplasty (PTRA) often fails to improve renal function in ARAS patients. Adipose tissue‐derived MSC are useful cell‐based therapy, but their potential for attenuating cellular injury in ARAS remains unclear. We hypothesized that replenishment of autologous MSC during PTRA would restore cellular integrity and improve renal function in ARAS pigs.