{'fraction_non_alphanumeric': 0.030855539971949508, 'fraction_numerical': 0.002805049088359046, 'mean_word_length': 5.932038834951456, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Plasma exchange: An effective method to eliminate neurotoxic lipophilic chemicals from blood

The Alzheimer’s Management by Albumin Replacement (AMBAR) trial demonstrated the clinical efficacy of plasma exchange (PE) with albumin replacement for slowing the progression of disease in patients with mild-to-moderate Alzheimer’s disease (AD). 1,2 Although the main hypothesized mechanism in AMBAR was a decrease in neurotoxic amyloid beta (A β ) amount, its quantification in the cerebrospinal fluid revealed no clear evidence in this regard, implying the pres-ence of alternative mechanisms beyond A β binding. At present, the elimination of dysfunctional albumin, inflammatory mediators, neurotoxic autoantibodies