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[Calculation by Supprian of the phase calendar of endogenous depressions--a statistical artifact?].

According to Supprian (10, 13, 14) the postulate of internal desynchronisation of drive and mood is a necessary condition for the estimation of the time-structure of endogenous depression. This hypothesis could not be substantiated in a longitudinal study of four depressive patients. A subsequent reanalysis of data, published by Supprian (13) contradicts the central postulate of internal desynchronisation. A critical review of other publications (10, 11, 14) suggests the assumption that the statistical analysis of this data might be erroneous too.