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Anencephaly in the United Kingdom and Republic of Ireland.

It is of great importance to those concerned with the intensive care of children that reliable predictive criteria for the development of the persistent vegetative state are established. This can be achieved only by detailed clinical, neurophysiological, and neuroradiological studies of the evolution of coma in childhood. When such coma in childhood does lead to a persistent vegetative state there are profound implications for the family, and many believe that this outcome represents a failure of intensive care medicine.