{'fraction_non_alphanumeric': 0.04679972470750172, 'fraction_numerical': 0.044735030970406056, 'mean_word_length': 4.983539094650205, 'pattern_counts': {'":': 0, '<': 1, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Minimally invasive esophagectomy/ gastroesophagectomy for cancer - Long term results from a single institution

Background: Esophagectomy is a complex operation. Minimally invasive esophagectomy (MIE) may decrease the morbidity and mortality of resection. The aim of this study was to produce long term outcome of MIE from a single center in Nepal.
Methods: Patients with squamous cell carcinoma and adenocarcinoma of esophagus/ gastroesophageal junction who underwent MIE between 2001-2018 were analyzed.
Results: 215 patients were taken for MIE during 2001-2018. There was 11.2% conversion rate. Totally MIE approach was performed in 43% cases and hybrid MIE in 57% cases. Mean operative time, intra operative blood loss, anastomotic leak, pulmonary infection, recurrent laryngeal nerve injury and in-hospital mortality were 246 min, 286 ml, 13.1%, 9%, 6.8% and 3%, respectively. Final histopathology revealed most common Stages III and IV in 51.2% and 36.1%, respectively. The median survival was 34 months and 5-OS was 27%. 5-OS was 27% and o% for R0 and R+ resection (p<.001). Median survival after radical and non-radical lymphadenectomy was 36 months and 25 months (p=.003), respectively. Responders to neoadjuvant treatment had the best survival.
Conclusion: MIE has got acceptable post operative morbidities. R0 resection, early stage of disease, radical lymphadenectomy and responders to neoadjuvant treatment had got the best survival results