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Physico-Chemical Studies on Aqueous Solutions of (Amantadine and Oseltamivir) with PEG, Maltodextrin and SLS Binary Complex Formation

The molecular interaction between the drug and solvent molecules are discussed. The study aims to increase the solubility, stability, sweetness of drugs by way of complexation. The ultrasonic velocity, density, and viscosity have been measured at 2MHz for the aqueous solutions of (i) Influenza Anti-Viral Drugs + PEG, Maltodextrin, and SLS at different concentrations at a temperature 303K. Some derived parameters from the measured parameters have been computed. These properties are ascribing to molecular interactions through hydrogen bonding. The total absorption can be considered as the sum of contributions from solute-solvent interactions with FTIR studies.