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study on comparison of severity markers in first wave and second wave of COVID-19 in tertiary care centre

Background: Haematological parameters have an important role in the early detection of the COVID19 disease. This study is aimed to study the hematological severity markers of COVID19 infected patients in first wave versus second wave in a tertiary care centre.  Methods: This is a retrospective study done in government medical college/government general hospital, Suryapet. We collected the information regarding patient’s data from hospital records who were admitted in the hospital during first wave in September 2020 and compared it with the patients admitted in the second wave in  May 2021. Results: In our study, a total of 341 patients with COVID19 infection admitted in our hospital were included. 136patients were admitted in first wave and 205 patients were admitted in the second wave. Out of 136 patients in first wave, 95 were admitted in non-ICU ward and 41 were included in ICU ward. We found that there is increased Absolute Neutrophil count, decreased Absolute Lymphocyte count and Platelet counts in second wave ICU patients. Conclusion: We conclude that based on the haematological parameters disease severity was more pronounced in second wave, especially ICU patients than first wave.