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P1-332 First insight into genetic diversity of Mycobacterium tuberculosis strains in Salvador, Brazil

This study constitutes a first attempt to describe the genetic population structure of M tuberculosis circulating in Salvador. A total of 56 confirmed cases of pulmonary tuberculosis, identified between March and June, 2008 were analysed using IS6110-restriction fragment length polymorphism (RFLP). The study population was characterised by male (71.4%) and over 30 years of age (68.7%). Forty-one isolates were found in a single pattern (73.21%), while 15 (26.78%) were found in group patterns, forming six clusters. The higher rate of diversity observed is much more suggestive of endogenous reactivation than recent transmission.