{'fraction_non_alphanumeric': 0.023923444976076555, 'fraction_numerical': 0.019138755980861243, 'mean_word_length': 5.109489051094891, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
In vivo angiogenic activity of interleukins.

Interleukin 1 incorporated into Elvax-40 (ethylene-vinyl-acetate copolymer consisting of 40% vinyl-acetate by weight) induces a rapid and strong angiogenic stimulus when implanted in rabbit corneas at a distance of 2.5 mm from the limbus. A constant and reproducible neovascular stimulus was observed with 5 ng per implant of recombinant human interleukin 1 alpha or 100 ng per implant of recombinant human interleukin 1 beta. At these concentrations, neither tumor necrosis factor nor interleukin 2 induced any neovascular stimulus. These data are interpreted as an indication for the possible role of interleukin 1 in angiogenesis of ocular (and other) tissues. As interleukin 1 is produced by various cells, it is hypothesized that this molecule may be the "unitarian angiogenic factor."