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Central Venous Catheter Infections: Clinical Aspects of Microbial Etiology and Pathogenesis

Infection is the leading complication associated with central venous access and one of the most important complications of parenteral nutrition therapy. Most of these infections are caused by gram-positive cocci. However, gram-negative bacilli and yeast infections have become problematic over the past decade. This article reviews the etiology, pathogenesis, management, and current treatment strategies, focusing on central venous access infections.