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Pituitary Gonodal Axis in Fertile and Infertile Human Males

Radioimmunoassay of serum level of PRL, LH, FSH, Testosterone and Estradiol were performed in normal fertile subjects and infertile patients (oligospermia and azospermia). The finding in normal fertile group may suggest that prolactin in human males has a role in steroidogenesis. Oligospermic and azospermic patients have hormonal pattern which is significantly higher than normal fertile group. Hyperprolactinemia was found in most cases of both infertile groups indicating that PRL has a significant role.