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Latent tuberculosis infection: diagnostic update before introduction of biological drugs

Screening for latent tuberculosis infection (LTI) in patients who are going to undergo treatment with biological drugs (TNF blockers and anti IL12/23) to manage moderate-to-severe psoriasis has become a significant issue in countries such as Spain, with one of the highest tuberculosis incident rates of Western Europe (13 new cases per 100,000 persons/year, according to the World Health Organisation) [1]. The interferon-γ release assay (IGRA) has recently been introduced as a relevant diagnostic [...]