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Bilateral Adrenal Hemorrhage in a Patient with Antiphospholipid Syndrome Following Reversal of Warfarin-induced Over-anticoagulation.

A syndrome (APS) is an autoimmune disease characterized by venous and arterial thrombosis in the presence of persistent laboratory evidence of antiphospholipid antibodies (aPL). A rare clinical manifestation of APS is bilateral adrenal hemorrhage (BAH), which is potentially life threatening [1]. The detection of BAH is a considerable diagnostic challenge. We present a case study and summarize our experience in the diagnosis and treatment of a rare case of BAH in a woman with known APS. We explain the pathogenesis and suggest a potential laboratory predictor for similar patients.