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Toxic effects of streptomycin and kanamycin upon the sensory epithelium of the crista ampullaris.

The pathological patterns of the sensory epithelium of the crista ampullaris of a guinea pig were studied after streptomycin and kanamycin administration. The silver reaction method and succinic dehydrogenase staining were applied for the entire surfaces of all specimens. Differences in sensitivity to antibiotics were confirmed in the sensory cells of the central and the peripheral regions of the crista (Lindeman, 1969 a).