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[An experience of intra-arterial thrombolytic therapy of ischemic stroke in Uzbek republic center of emergency care].

Acute period of stroke is a crucial stage of the disease. The differential therapy in the first 3-6 h from the onset of acute ischemic stroke, so-called "therapeutic window", is of special importance. Obviously, favorable clinical outcome in such patients is largely depends on the early recanalization during "therapeutic window". Presented, are the results of intra-arterial thrombolysis in patients with ischemic stroke, which reveal its high therapeutic effectiveness. Though there was limited clinical evidence for a high effect of recanalization of intra-arterial thrombolysis, this approach opens new perspectives for large scale clinical investigations using endovascular methods in thrombolytic therapy of patients with ischemic stroke.