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Effect of shunt surgery on spleen size, portal pressure and oesophageal varices in patients with non‐cirrhotic portal hypertension

Shunt surgery is considered to be the treatment of choice in patients with non‐cirrhotic portal hypertension. There is little data on the effect of side‐to‐side lieno‐renal (SSLR) shunt on oesophageal variceal size, splenic size and splenic pulp pressure (SPP) in patients with non‐cirrhotic portal hypertension. We evaluated pre‐ and postoperatively endoscopic grading of varices, splenic size and SPP for predicting shunt patency in 86 patients with non‐cirrhotic portal hypertension: 56 with extrahepatic portal venous obstruction (EHPVO) and 30 with non‐cirrhotic portal fibrosis (NCPF). The EHPVO patients with patent shunts (n= 47) showed significant reduction in SPP (pre‐operative 43.56±7.9 vs postoperative 29.96±7.7 cm of saline), splenic size (6.5±2.8 vs 4.00±2.6 cm below costal margin) and varices grades (2.96±0.5 vs 0.92±0.8). Patients with blocked shunt (n= 9) did not show significant reduction in SPP and varices grades. However, there was reduction in spleen size (8.6±3.0 vs 6.3±4.3). In the NCPF group, 28 had patent shunts and showed significant reduction in SPP (46.3±13.5 vs 33.8±7.6 cm of saline), splenic size (9.1±3.3 vs 6.8±4.6 cm below costal margin) and varices grades (2.8±0.7 vs 1.05±0.96). As only two patients with NCPF had blocked shunts, no statistical comparison between patients with patent and patients with blocked shunts could be done. In conclusion, following SSLR, there is a significant reduction in SPP and varices grades in patients with patent shunts. Endoscopic grading of varices can be used to predict shunt patency. However, spleen size is not a good criteria for predicting shunt patency.