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An observational study to assess the lipid profile of hypertensive patients in Southern Odisha

Background: Rated among the most common disease worldwide, Hypertension is fast becoming a cause of significant morbidity and mortality. Owing to its widespread it has become one of the most common risk factors of serious disease including cardiovascular diseases (CVD) along with other illness like renal malfunctioning, myocardial infraction and even leads to loss of vision. There are various other biomarkers of the hypertensive patients that help in realizing the real threat of the cardiovascular diseases among those who are suffering from hypertension. The discrepancies in the different lipid profile biomarkers like total cholesterol (TC), low-density lipoproteins (LDL), serum levels of triglycerides (TG) pose a great risk for the development of CVDs. Aim: To assess the lipid profile of the hypertensive patients in Southern Odisha Materials and Methods: It was n observational study undertaken at MKCG Medical CollegeBerhampur, Ganjam (Odisha). One hundred fifty patients were included in the study belonging to both the genders. The duration of the study was from June 2019 to November 2019. The patients were divided into two groups, group 1 with 70 patients who were non-hypertensive and 80 patients in group 2 who were hypertensive. CHOD-PAP was the method used to measure the serum total cholesterol. The GPO-Triender method was used to assess the triglycerides. Results: Sixty per cent of the patients in the non-hypertensive group were males, and 70% of the patients in the hypertensive groups were males. The SBP for the non-hypertensive patients was 120±4.12 while the DBP was 80.1±3.21. On the other hand, the SBP for the hypertensive group was 1699.10, and the SBP was 96.12±5.06. The mean total cholesterol for the non-hypertensive group was 164.25±3.99, mean Triglycerides was 129.9 ± 8.3, mean HDL was 47.26 ± 5.54, mean LDL was 93.76 12.06, and mean VLDL was 26.98 ± 2.67. On the flip side, the mean total cholesterol for the hypertensive group was 168.9 ± 6.27; mean Triglycerides was 181.57 ± 31.9, mean HDL was 41.96 ± 2.65, mean LDL was 179.6 20.08, and mean VLDL was 37.54 5.60. Conclusion: In light of the above results, it was identified that dyslipidemia was found to be closely associated with hypertension. It was also concluded that an increase in the blood pressure would result in disturbing the lipoprotein metabolism. Keywords:  SBP, DBP, Hypertension, Lipid Profile.