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Short-Term Reproducibility of Impression Cytology

Goblet cell impressions free from epithelial cells could be collected more consistently from the rabbit conjunctiva by creating a space between the applied cellulose acetate filter and the tissue surface. Successive impressions taken over the same region of the conjunctiva could not be matched. When tight control of the area being sampled was established, the impressions left by cells on successive filters varied widely in intensity.