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Prevention of Postmenopausal Bone Loss by a Low‐Magnitude, High‐Frequency Mechanical Stimuli: A Clinical Trial Assessing Compliance, Efficacy, and Safety

A 1‐year prospective, randomized, double‐blind, and placebo‐controlled trial of 70 postmenopausal women demonstrated that brief periods (<20 minutes) of a low‐level (0.2g, 30 Hz) vibration applied during quiet standing can effectively inhibit bone loss in the spine and femur, with efficacy increasing significantly with greater compliance, particularly in those subjects with lower body mass.