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Presidential address: Thirty years of progress and problems in clinical neurology

Research has transformed clinical neurology in the past thirty years, but we are faced with a paradox. Advances in basic sciences and better training for clinical investigators have accelerated the practical application of new knowledge. Now, just when neurological sciences are moving so rapidly, economic and other problems have threatened clinical investigation. It will take ingenuity and steadfast effort to continue research that is directly related to neurological diseases.