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ANTIBACTERIAL ACTIVITY OF CAMELLIA SINENSIS LEAVES AGAINST STAPHYLOCOCCUS AUREUS AND ESCHERICHIA COLI 1

Drug resistance by pathogenic microbes is the big threat for human health. The increasing interest in the powerful biological activity of medicinal plant phenolics and flavonoids outlined the necessity to determine their antimicrobial activity. The phytochemical analysis showed the presence of most important bioactive constituents’ tannis, flavonoids, alkaloids and steroids while the absence of glycosides, terpenoids and saponins. The total phenolic compound was 0.7 grams while as flavonoid content was 14mg/gram in the leave extract of Camellia sinensis. The Fourier transforms infrared spectroscopy showed the presence of functional groups. The phenolic extract of Camellia sinensis showed the antimicrobial activity against Staphylococcus aureus and Escherichia coli by showing highest zone inhibition around the bacterial colonies when compared with standard antibiotics Tetracycline, Gentamycin and Neomycin.