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Quantitative analysis between visual mismatch negativity and psychopathology scale for schizophrenia

Visual mismatch negativity (v-MMN) in electroencephalographic (EEG) record provides an index of pre-attentive information processing of the brain. v-MMN is considered to reflect schizophrenia. The positive and negative syndrome scale (PANSS) is usually used in clinical diagnosis on patients with schizophrenia for estimating the degree of disorder. In this study, the relationship between v-MMN and PANSS was analyzed. Characteristic parameters of peaks including N1, N2, P300, and MMN were established respectively. Estimated function was constructed by selected parameters. P300 was most significant characteristic related to all items of PANSS.