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Sensitivities of Achatina giant neurones to peptides isolated from mollusca.

Sensitivities of the Achatina giant neurones to the peptides isolated from Mollusca were examined by their local application of the pneumatic pressure ejection under current clamp. The peptides tested and their effects were as follows: Ser2-MIP (inhibitory). CARP (inhibitory), oxytocin (excitatory), SPCB (excitatory), alpha-BCP (no effect). ELH (no effect). APGW-amide (inhibitory) and FMRFamide (inhibitory). Membrane conductance (g) of a neurone, d-RPeAN, measured under voltage clamp, was unexpectedly decreased by SCPB during inward current (Iin) caused by the peptide.