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DYNAMICS OF FREE RADICAL OXIDATION INDICES AND ANTIOXIDANT PROTECTION IN MALE RATS’ HEART UNDERGONE VARIOUS TYPES OF STRESS

Any change of external or internal environment causes body’s responses that facilitate its adaptation. Pathogenesis of stress reaction study is always topical as it is aimed at the investigation of optimal adaptation mechanisms to impaired agents. The aim – to study the dynamics of free-radical oxidation indices and antioxidant protection in male rats’ heart undergone chronic prenatal, postnatal stress and their combination. Material and Methods. The study was performed on 44 white non-pedigreed pubertal three-month-rats. Prenatal stress was induced by keeping pregnant female rats in narrow pencil case for an hour. Postnatal stress was induced in 1.5 to three-monthrats by keeping them in cages with living space restriction twice as much. Combined stress comprised using two methods.