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Primary intracranial mesenchymal chondrosarcoma

Introduction Mesenchymal chondrosarcoma is a rare but well-defined neoplastic entity, which can arise primarily in bone as well as in extraosseous sites (Lichtenstein and Bernstein, 1959; Salvador et al., 1971; Guccion et al., 1973), including the meninges (Scheithauer and Rubinstein, 1978) or in the brain (Raskind and Grant, 1966). We describe here a primary intracranial mesenchymal chondrosarcoma involving both dura mater and the occipital bone. The neoplastic chondrocytes in this tumour contain cytoplasmic glial fibrillary acidic protein (GFAP) as in the chondrocytes of the hyaline cartilage of the trachea and the astrocytes of the brain.