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Effects of cagA+ and cagA– strains of Helicobacter pylori on the human gastric mucus layer thickness

Background:  Infection with cytotoxin‐associated gene A (cagA) Helicobacter pylori is associated with severe gastric diseases, with contradictory views being expressed concerning the effect of H. pylori on the gastric mucus thickness. The aim of the present study was to differentiate between the effect of cagA+ and cagA– strains on gastric mucus thickness.