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Driving the Growth Cone

Growth cones are the specialized tips of neuronal axons that make their way through the nervous system in search of a correct target. In his Perspective, Caroni outlines the signaling mechanisms that help steer the growth cone as it moves, and discusses a report by
 Song
 et al .
 in this week9s issue that completes our understanding of how the cell is attracted or repulsed by various molecules in its environment.