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THREE MONOCLONAL ANTIBODIES SPECIFIC FOR HUMAN CLASS II ANTIGENS DETECT RT1B‐LINKED POLYMORPHISMS IN RAT B CELLS

Three monoclonal antibodies HU‐11, HU‐32, and HU‐33, which recognize two distinct polymorphic determinants of human class II antigens, were found to cross‐react with rat B cells carrying an RT1B region‐associated specificity Ba‐2.6. This is the first report demonstrating that xenoimmune antibodies raised against polymorphic determinants of human class II antigens are able to detect polymorphic determinants of class II antigens in a third party species.