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The disposition, morphology and innervation of cardiac specialized tissue in the guinea-pig.

The morphology of the atrioventricular nodal area was originally described by Tawara (1906) and subsequently supported by the reports ofmany workers. Recently it has been observed that the cellular arrangement in the rabbit and human (De Felice & Challice, 1969; Anderson, 1971; Anderson& Latham, 1971) may differ from the original description. Since much of the evidence to support this differentiation in the rabbit was adduced from the use of a combined neurohistochemical-histological technique, it was decided to apply this technique to another of the species studied by Tawara (1906), namely the guinea-pig. In addition to the atrioventricular area, the entire heart was studied in an attempt to elucidate the full extent of cardiac specialized tissue in this animal.