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Clastogenic and Mutagenic Effect Induced by Some Fast Foods

Genotoxic compounds in the diet represent a truly international problem. This problem was recognized in Japan and the United States of America from several years ago by the application of in vitro mutagenicity tests to prepared and unprepared components of our diet. Now new discoveries are appearing every day concerning genotoxic compounds in our food supply from all over the world. It seems likely that naturally occurring genotoxic compounds in the diet as well as genotoxic compounds formed during storage, preparation, and digestion of the food are important for the induction of cancer in humans and of hereditary changes in human germ cells. Other scientific data indicate that dietary constituents have the potential to modify the genotoxic effect of these compounds in humans. These findings indicate new possibilities for the prevention of human diseases of genotoxic origin through relevant changes in the composition of the diet. (Amara et al., 2008).