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Innovation in Clinical Practice

Every new class of agents in psychopharmacology has begun with clinical innovation and novel observations at the outset. Clinicians in practice can either follow the standard of care to the letter, or they can innovate and try different ideas. An excessively arbitrary distinction is drawn between research, seeking new knowledge; and practice, seeking to help the patient. Often our knowledge is limited, and research does not occur on certain topics. Then clinicians are faced with the dilemma of how to help the patient by seeking new knowledge. This kind of clinical innovation has been central to progress in psychiatry, as in the case of lithium, and it should not be lost.