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Human endometrial morphology around the time of implantation in natural and artificial cycles.

Grosser (1910) stated that the most important physiological function of the endometrial cycle is the preparation for the reception of a fertilized ovum (implantation), while menstruation is only a secondary process, a degeneration of the 'mucus membrane' which has not been able to fulfil its purpose. From the earlier work of Hertig et al. (1956), it is thought that implantation starts \m=~\6 days after ovulation. Croxatto et al. (1978) found that, in the natural cycle, the human embryo usually arrives in the endometrial cavity 96 h or more after the luteinizing hormone (LH) surge. In most in-vitro fertilization programmes, fertilized embryos are transferred to the endometrial cavity