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[The morphology and formation of micronuclei of blood lymphocytes in man after cessation of gossypol administration].


 2 groups of men were compared under controlled experimental conditions. Group A consisted of men who were administered gossypol over a period of 2 months (subgroup I), and 9 months (subgroup II); those in group B were never administered gossypol. This experiment was performed in order to determine the levels of formation of micronuclei of blood lymphocytes in males after the administration of gossypol is terminated. The results indicate that subgroup I had a slightly higher evidence of micronuclei than subgroup II, but remarkably higher than group B. Among the blood lymphocytes, scientists discovered 1 with 22 micronuclei capable of generating more micronuclei. It is suggested that gossypol might possibly cause genes to break up.
