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Effect of Gut Microbiota Eradication on Adaptive Thermogenesis in Mice

The gut microbiota is identified as an important regulator of metabolism and plays a relevant role in the development and progression of obesity. Among the mechanisms proposed to explain the regulation of energy metabolism by the gut microbiota, is its influence on host's energy expenditure. One of the components of energy expenditure is the adaptive thermogenesis, resulting from the activity of thermogenic adipose tissue, consisting of the beige or brown adipocyte. This type of thermogenesis seems to be important for the metabolic health of rodents and humans.