{'fraction_non_alphanumeric': 0.022556390977443608, 'fraction_numerical': 0.02406015037593985, 'mean_word_length': 4.219607843137255, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Effects of circadian rhythm on membrane ion transport ATPases activity and tissues in the liver of mice

Unnatural daily cycles affect the lives of animals in many ways. The present study investigates the influence of circadian cycles on the activity of ATPase enzymes and the histological structure of the liver in mice (Mus musculus) for a period of 60 days. The study included fifty female and male mice, which were divided into five groups based on different exposure periods. The control group was maintained in 12 h of darkness and 12 h of light, whereas the four other groups were maintained in 8 h of darkness and 16 h of light, 8 h of light and 16 h of darkness, 24 h of light, or 24 h of darkness. The results showed an increase in the activity of Mgdependent and Na/K-activated ATPases in all the groups, except for the control group. The activity of Na/K-activated ATPase was increased among the 16/8 h L/D and 16/8 h D/L experimental groups compared to the control group. Moreover, the activity of vacuolar ATPase observed in the liver was increased in the 16/8 h L/D and 16/8 h D/L experimental groups but was reduced in the 24 h L and 24 h D groups. The study concluded that there is an association between variations in photoperiods and histological abnormalities in the mouse liver, which is regulated by enzymes.