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Screening for Diabetes in a Prenatal Clinic

Over a 3-year period, 1269 patients of 8288 attending a prenatal clinic were investigated for abnormal glucose tolerance because of obesity, a family history of diabetes, previous birth of a large infant, poor obstetric history or glucosuria. Ninety-one or 1.1% of the total prenatal population were found, for the first time, to have abnormal glucose tolerance. To delineate the population at greater risk, the significance of various indications for screening were evaluated by statistical analysis. From the information derived, the detection of abnormal glucose tolerance rose exponentially with each additional screening indication. Thus, multiple indications for screening, in a given subject, indicate her carbohydrate metabolism must be investigated immediately.