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Ambient fine particulate matter induces endothelial progenitor cells apoptosis via reactive oxygen species formation

Bone marrow (BM)‐derived endothelial progenitor cells (EPCs) play a critical role in the angiogenesis. Some environmental insults, like fine particulate matter (PM) exposure, significantly inhibit EPCs‐mediated functions. However, the mechanisms remain largely unknown. The present research was to study the detrimental effects of PMon EPCs and explore the potential mechanisms.