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Isolation and Characterization of Bioactive Anti-inflammatory
Flavonoids from Arisaema tortuosum Tubers

Present study was focused on the isolation and characterization of the anti-inflammatory compound(s)
from the methanolic extracts of Arisaema tortuosum tuber by column chromatography, TLC, FT-IR,
1H, 13C NMR and HR-MS. Among all the fractions obtained A. tortuosum fraction 3 (PC-1) and
fraction 5 (PC-2) showed significant in vivo anti-inflammatory activity. This study endorsed that the
isolated bioactive compound PC-2 showed better anti-inflammatory activity at a dose of 25 mg/Kg
BW. The results indicate that PC-2 and PC-1 methanolic extract of A. tortuosum tuber may be competing
for the tent in the therapy of inflammatory ailments.