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Linked color imaging identified ulcerative colitis‐associated colorectal cancer: A case report

Ulcerative colitis (UC)-associated colorectal cancer (CRC) is an important problem in long-term management of patients with UC. Lesions with background chronic inflammatory mucosa may often be difficult to identify even by endoscopic observation. Traditionally, a random biopsy strategy was recommended, but problems with patient compliance, increased burden on endoscopic staff and pathologists remained. The effectiveness of target biopsy has been reported in recent years. Currently, the most recommended method is chromoendoscopy by indigocarmine spraying. Although it has not been established, effectiveness of observation by narrow band imaging and magnified endoscopy has also been investigated. For target biopsy regimen, how to elevate the lesion is the most important task. Linked color imaging (LCI) has recently been developed using a laser endoscopic system (Fujifilm Co., Tokyo, Japan) to provide an expanded color range, resulting in more emphasized color difference between red and white. Here we report a case with successfully identified UC-associated CRC using LCI (EC-L600ZP; Fujifilm Co.) for the first time. A 53-year-old man with a 6-year history of UC developed UC-associated CRC in the rectum. LCI could