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Colonic gas homeostasis: Mechanisms of adaptation following HOST‐G904 galactooligosaccharide use in humans

We have shown that a galactooligosaccharide prebiotic administration (HOST‐G904) initially increased intestinal gas production and this increase declined back to baseline after 2 week administration. Our aim was to determine the mechanism of microbiota adaptation; i.e., to determine whether the net reduction is due to decreased overall production or increased gas consumption.