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Secretion of Heterologous Proteins from Saccharomyces Cerevisiae

In recent years considerable progress has been achieved on the heterologous gene expression and protein secretion in the yeast Saccharomyces cerevisiae. The variety of natural yeast secretory signal sequences being utilized for heterologous protein secretion are reviewed. The usefulness of the yeast pheromone, α‐factor leader sequence on the secretion of foreign proteins is emphasized.