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Diffuse backscattering Mueller matrix analysis for tissue diagnostics with polarized light

We have developed a Monte Carlo algorithm that calculates all sixteen, 2D elements of the diffusing back scattering Mueller Matrix for highly scattering media. Using the Stokes-Mueller formalism and scattering amplitudes calculated with Mie theory, we are able to consider polarization dependent photon propagation in highly scattering media. The numerically computed matrix elements are compared to experimental data obtained from particle suspensions with different particle sizes and fibroblast cell suspensions. The numerical results show good agreement in both azimuthal and radial direction with the experimental data, and suggest that in the fibroblast suspensions subcellular structures with a typical size of 200 to 300 nm dominate the back scattering behavior.