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Serum Potassium during Regional Anaesthesia with special reference to the effects of adrenaline

Abstract: Hypokalaemia may occur in connection with regional anaesthesia. The main purpose of this thesis was to: (1) Evaluate the effect of some major forms of regional anaesthesia on the serum potassium (S–K) level. (2) Determine whether the response to adrenaline with regard to the S–K level is different during and after surgery compared to a plain experimental situation and, if so, decide if this can be explained by an altered responsiveness in the β–adrenoceptors. (3) Study ECG disturbances attributable to adrenaline and to hypokalaemia caused by the local anaesthesia. (4) Find out whether differences in health status and medication constitute risk factors in developing marked preoperative changes in the S–K level.