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Primary gastric Ki‐1 positive anaplastic large cell lymphoma: A report of two cases

Two cases with primary gastric Ki‐1 positive anaplastic large cell lymphoma are presented. Morphologic features of both cases involved pleomorphism of the neoplastic cells, fibrosis and lymphatic infiltration. The neoplastic cells in both cases were positive for BerH2 (CD30), LCA(CD45), lysozyme and alpha‐1‐antitrypsin (α1‐AT). In additional case, the neoplastic cells were additionally positive for MAC387 and (α1,‐antichymotrypsin (α,‐ACT). The neoplastic cells in these cases were negative for L26(CD20), UCHL‐1 (CD45RO), DAKO CD3 and epithelial membrane antigen (EMA). According to the results of the phenotypic studies, the authors consider that the neoplastic cells have some of the features of histiocytes.