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Microbial Diversity in Patients with Gastroduodenal Diseases

H. pylori infection is mainly spread in 
the kind of gastroduodenal diseases: chronic gastritis, peptic ulcer disease, 
MALT-lymphoma, gastric cancer. According to certain literature, the mentioned 
bacterium causes diseases of other visceral organs of humans. Study of the 
aggravating impact of this infection is under the attention of the scientists. 
However, other infectious agents, including fungi, other bacteria, parasites, 
and viruses and their role in different gastroduodenal diseases are not studied 
enough. The aim of our study was to identify mucous (parietal) gastroduodenal 
microflora in patients with different diseases of this zone. 390 patients with 
chronic gastritis (CG), peptic ulcer diseases (PUD) and gastric cancer (GC) 
were included in the study. The resection materials and biopsy specimens were 
taken during the operation or endoscopy procedures. Identification of strains H. pylori, Candida spp and others was performed by established methods, on the 
basis of morphological, tinctorial, cultural and biochemical properties. Microflora of patients with different gastroduodenal diseases is diverse enough. It is represented 
by facultative, obligate anaerobes, microaeropilic bacteria. More frequently, there were H. pylori and Candida sp, as well as in associations and monocultures. The 
obtained results confirmed the wide distribution of H. pylori and Candida spp and their frequent coexistence in patients with gastric cancer, chronic 
gastritis and peptic ulcer disease. Microflora of patients with CG and GC was represented 
on 11 species. Microflora 
of patients with PUD-13 species was more diverse.