{'fraction_non_alphanumeric': 0.023185483870967742, 'fraction_numerical': 0.029233870967741934, 'mean_word_length': 4.841176470588235, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Testicular 17-oxosteroid secretion in response to human chorionic gonadotrophin in dogs pretreated with aspirin.

The 17-oxosteroid secretory response of the testis to human chorionic gonadotropin (HCG) was studied in 14 dogs pretreated with aspirin a potent inhibitor of prostaglandin synthesis. In 4 dogs pretreated with 20 mg/kg aspirin the response to HCG 15 minutes later was significantly (p less than .01) less than in animals not pretreated with aspirin. Although the secretion of 17-oxosteroid remained lower at 30 60 and 120 minutes the difference was not significant (p greater than .05). However the response to HCG was significantly (p less than .01) diminished at all time periods studied when the dose of aspirin was increased to 200 mg/kg. The diminished response to HCG was not dependent on blood flow through the testis. The results indicate that prostaglandins in testicular tissue may be involved in those mechanisms required for the initial action of luteinizing hormone.