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THERAPEUTIC APPROACHES TO THE CORRECTION OF COGNITIVE IMPAIRMENT IN PATIENTS WITH HYPERTENSION AND TYPE 2 DIABETES.

OBJECTIVE
The aim: Was to improve the effectiveness of the treatment of cognitive impairment in patients with hypertension and type 2 diabetes.


PATIENTS AND METHODS
Materials and methods: 56 patients (11 women and 45 men, average age 61.7 ± 4.3 years) with hypertension II, 2 degree and type 2 diabetes (average severity, subcompensation stage) were examined. 40 patients had moderate CI and 16 had mild CI. After the examination, the patients were divided into two groups and treated accordingly. The control group consisted of 20 healthy individuals.


RESULTS
Results: Vascular brain lesions that cause hypertension and diabetes very often lead to impaired cognitive function whose therapeutic correction has received little attention, especially in the pre-operative stages. 56 patients have been examined to study the efficacy and safety a combination of Phenibut and Ipidacrine as an additional therapy to standard basic treatment (antihypertensive and hypoglycemic) for the correction of cognitive dysfunction in patients with comorbidity of hypertension and type 2 diabetes mellitus.


CONCLUSION
Conclusions: One month after the beginning of the treatment, an improvement in psycho-emotional state and psychometric parameters was identified, which was manifested by an increase in concentration of attention, memory, psychomotor functions, speech activity together with normalization of blood pressure and metabolic parameters.