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[The study on plasma ET and NO of patients with sudden hearing loss].

OBJECTIVE
To study the significance of plasm NO and ET in sudden hearing loss.


METHOD
We studied the plasma endothelin (ET) and NO in 32 cases of sudden hearing loss with radioimmunoassay (RIA) and nitrate reductase (NR) by using RIA and NR.


RESULT
The content of plasma ET in sudden hearing loss group is higher than that in control group (P < 0.01), but the NO is lower (P < 0.01). The contents of plasma NO and ET between sudden hearing loss and treated sudden hearing loss group and that between the effective treatment group and effectless treatment group have significant differences (P < 0.01).


CONCLUSION
The contents of plasma NO and ET will remarkably change during the process of sudden hearing loss and may accelerate the happening and development of the disease.