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Common acute lymphoblastic leukemia preceded by hypercalcemia in an infant

A case of common acute lymphoblastic leukemia (ALL) preceded by hypercalcemia was observed in an infant. A high blood level of parathyroid hormone related protein (PTH‐rP) was detected during the first examination at Ohashi Hospital. Treatment with antineoplastic agents led to complete remission. The blood PTH‐rP level decreased as a result of treatment. PTH‐rP produced by leukemic cells was thought to be the cause of the hypercalcemia.