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Effect of X-rays alone or combined with diethylnitrosamine on cancer induction in mouse liver.

The possible combined effects of the initiator diethylnitrosamine (DEN) with X-rays on cancer induction in infant C57BL/Cnb mice were evaluated. Preliminary data show that a dose of X-rays administered 7 days before a single injection of DEN was more effective in inducing liver nodules than when administered 7 days after DEN administration.