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Teaching Old Microscopes New Tricks

There are many transmission electron microscopes (TEMs) that have provided years of reliable service and good images, but they lack the positioning systems that are standard on the newest microscopes. A precise digital positioning capability is essential for many quantitative stereological studies and relocating specific features on a grid. For many of the older TEMs, retrofitting them with a digital positioning system is not an option, or at least a very expensive upgrade. Now Martin Hohmann-Marriott, William Sharp, Robert Roberson, and Robert Blankenship have described the hardware and software that offer a second life to these older microscopes.