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[Analysis of prognostic factors in patients with carcinoma of the thoracic esophagus].

Prognostic factors in patients with carcinoma of the thoracic esophagus were analysed. From May 1972 to February 1989, 361 cases were resected in our department. Cases of histological curability 0, double cancer, death within 30 days after operation, death due to other diseases and cancer except squamous cell carcinoma were excluded, and 170 were chosen for this study. We classified these cases into two groups according to the survival period; Group 1: cases died within 2 years after operation, Group 2: cases lived more than 2 years. Factors analyzed were as follows; sex, age, location of the lesion, radiological classification, radiological vertical extension, axial deviation of the esophagus, endoscopic classification, endoscopic horizontal location, resectability, longitudinal diameter, histologic differentiation, depth of invasion, degree of lymphnode metastasis, range of lymphnode metastasis, lymphatic invasion, blood vessel invasion, intraepitherial spread, intramural metatasis, histologic stage and histologic curability. Factors related to prognosis were age, radiologic classification, depth of invasion, degree of lymphnode metastasis, histologic stage and histologic curability. In the next step, these cases were also classified into three groups according to the degree of lymphnode metastasis (n(-), n1 + 2(+), n3 + 4(+) and factors which influenced prognosis were analysed in each group. In the group without lymphnode metastasis, there was a statistical difference in survival rate between cases with intramural metastasis and cases without that. In groups with lymphnode metastasis (n1 + 2(+), n3 + 4(+), any factors such as the degree and range of metastasis or intramural metastasis had no influence on prognosis. So it was concluded that lymphnode metastasis itself was an important factor for prognosis.