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Reactions to awareness of activated protein C resistance carriership: a descriptive study of 270 women

Background.  Around 25 million Caucasian women are carriers of the FV Leiden mutation that causes activated protein C (APC) resistance. This is a heritable condition with a lifelong increased risk of venous thromboembolism. We performed this study to investigate women's reactions to their awareness of being APC‐resistant and the consequences of this awareness.