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A previously unreported surgical technique utilizing five different grafting materials to successfully achieve simultaneous alveolar regeneration and closure of a large oronasal defect.

This case report describes the successful surgical and restorative management of an unusual cyst-granuloma combination that had expanded to perforate the labial and nasal parts of the maxillary bone. Enucleation and curettage of the lesions resulted in a large oronasal communication that presented a reconstructive challenge. Five different graft and/or barrier materials were used to close the oral and nasal openings and to regenerate the alveolus for implant placement and for aesthetic prosthetic restoration.