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Minimizing rectal and urinary complications in prostate brachytherapy.

With any therapy for early prostate cancer, control must be evaluated with a view to toxicities. Brachytherapy may be associated with urethral and rectal toxicity and erectile impotence. Patients with large glands or significant symptoms before treatment are at greatest risk. Long-term toxicity can be minimized by understanding the tolerance of the normal tissues and meticulous placement of the radioactive seeds.