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Constructing gene network based on biclusters of expression data.

Two genes can be co-regulated and possibly have the similar function if they are similarly expressed, which provides a theoretical basis for construction of gene regulatory networks using gene expression data. Herein, a new method of gene regulatory network was constructed based on biclusters in this paper. Given a bicluster, this paper analyzes the correlation between genes in the clusters and then constructs the gene regulatory network by selecting genes with a correlation coefficient.