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Probing personalized genetic platforms for novel molecular clues for circadian chronotype.

Chronotype (also referred to as morningness-eveningness or diurnal preference) is the tendency to be an early “lark” (alert and preferring to be active early in the day) or a late “owl” (alert and preferring to be active later in the day). Chronotype shows considerable interindividual variation and is the most frequently measured circadian rhythm trait. This trait can be evaluated in an individual via the completion of a self-reported questionnaire, such as the Horne-Ostberg Morningness-Eveningness Questionnaire (1)or the Munich Chronotype Questionnaire (2). These are the most commonly utilized measures of circadian phase preference (3,4).