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Abnormal F-18 FDG uptake in two epidermoid cysts on PET/CT.

We report a case of a 72-year-old woman with a history of papillary thyroid cancer imaged with positron emission tomography (PET)/ computed tomography (CT) because of an increased thyroglobulin level and negative whole body iodine and CT scans. A near whole body F-18 2-deoxy-D-glucose (FDG) PET/CT study showed 2 well defined metabolically active soft tissue nodules in the scalp. Clinical examination of the patient was subsequently performed which identified 2 epidermoid (or sebaceous) cysts which had been present unchanged since childhood. A repeat PET/CT study performed 2 years later showed no change in these findings.