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Tetrahydrotriamcinolone and triamcinolone. II. Effect on xenograft reaction in rabbits.

Triamcinolone (TA) and tetrahydrotriamcinolone (THTA) are similar in structure and ocular penetration capabilities but differ markedly in pressure-elevating potential in susceptible individuals. The present study, using pig-corneal xenografts in rabbits, showed a small effect in preventing rejection using 0.25 per cent THTA, while 0.25 per cent TA and 0.001 per cent dexamethasone phosphate were effective.