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Hepatocellular carcinoma in non-cirrhotic liver.

Hepatocellular carcinoma in a non cirrhotic liver Background: The appearance of hepatocellular carcinoma in non-cirrhotic livers is uncommon. Material and Method: We report a 62 years old woman presenting with a liver mass that was subjected to a left hepatectomy. Results: The pathology report disclosed a poorly to moderately differentiated hepatocellular carcinoma. The surrounding liver tissue was normal. Immunohistochemistry identifi ed intracytoplasmic α-1 antitrypsin granules, confi rming the suspicion of α-1 antitrypsin defi ciency.