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Literature review of the adverse events associated with botulinum toxin injection for the masseter muscle hypertrophy

Masseteric hypertrophy is a benign condition characterized by the enlargement of the masseter muscles. A square‐shaped jawline due to masseter muscle prominence or hypertrophy is one of the general characteristics of the Asian face, making it a frequent target for esthetic treatment requests. While the application of botulinum toxin on the masseter muscle is an off‐label use, it is very popular in Asian countries. However, comprehensive reviews of the complications associated with this procedure remain limited in scope.