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Active chlordiazepoxide metabolites in a patient needing life support after treatment of alcohol abstinence

It is important to treat alcohol withdrawal syndrome to ease symptoms and avoid severe complications including seizures and delirium tremens. Benzodiazepines with a long half-life are often the preferred treatment. In a meta-analysis from 2011,[1] chlordiazepoxide tended to perform better than other benzodiazepines and is accordingly often used. Chlordiazepoxide has several pharmacologically active metabolites.