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[Stomach cancer occurring after the radiation and chemical therapy of a lymphosarcoma].

A case of the development of gastric adenocarcinoma in a woman of 47 who for the previous 9 years had been treated for lymphoplasmocytic lymphosarcoma is described. The patient periodically received courses of polychemotherapy and twice radiotherapy on the stomach area because of the affection of the stomach detected by roentgenological examination and endoscopy with gastrobiopsy. In the past two years the patient underwent multiple endoscopic examinations demonstrating over time the changes in the gastric mucosa which initially showed superficial adenomatous outgrowths of the proliferating epithelium in the presence of marked atrophy and intestinal metaplasia. Gradually the signs of dysplasia increased in them and finally adenocarcinoma was established. Resection of the stomach revealed a highly differentiated adenocarcinoma in the form of an exophytic node 2 x 2 x 1 cm in size growing into the submucous layer.