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ABO blood group and susceptibility to urinary tract infection: no evidence for involvement of isohaemagglutinins.

Investigations of the possible mechanisms underlying the increased susceptibility of women who are blood group B and non-secretors of water-soluble blood group antigen to recurrent urinary tract infection (UTI) revealed that isohaemagglutinins are not involved in bactericidal killing or agglutination of 8 serotypes (1,2) of Escherichia coli frequently associated with UTI. The implications of these results and possible areas for future studies are discussed.