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Some measurements of protection against paratyphoid Salmonella and Escherichia coli by competitive exclusion chickens.

SUMMARY The crop and cecum were the major sites of Salmonella colonization. A technique to determine the possible adherence of Salmonella to the epithelial wall of the cecum demonstrated that Salmonella adhered firmly. Protection following introduction of the native gut microflora began within 2 hr post-treatment, but optimum protection was not established until 32 hr post-treatment. The protection of chickens afforded by native gut microflora against combined challenge by Salmonella typhimurium and pathogenic E. coli (0138) was demonstrated.