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Functional constipation is associated with alterations in thalamo‐limbic/parietal structural connectivity

Functional constipation (FCon) is a common functional gastrointestinal disorder (FGID) with a high prevalence in clinical practice. Previous studies have identified that FCon is associated with functional and structural alterations in the primary brain regions involved in emotional arousal processing, sensory processing, somatic/motor‐control, and self‐referential processing. However, whether FCon is associated with abnormal structural connectivity (SC) among these brain regions remains unclear.