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Seasonal Variation in Bromophenol Content of Polysiphonia lanosa

The bromophenol content of Polysiphonia lanosa, determined by GLC-MS, was shown to vary considerably between late spring and early autumn. The lowest content was found in material collected in early May and then the levels rose until a peak was reached in July. When the extracts were tested for cytotoxicity against DLD-1 cells, a direct correlation was shown between cytotoxicity and bromophenol abundance, confirming that these compounds are the ones responsible for the cytotoxicity of the species.