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[Study on isolation of Chlorogenic acid from Eucommia ulmoides leaves by ultrafiltration technique].

OBJECTIVE
To isolate and purify Chlorogenic acid from Eucommia ulmoides leaves by ultrafiltration technique.


METHODS
Chlorogenic acid transferring ratio was investigated by temperature, pressure, time, cut-off molecular mass.


RESULTS
The optimal conditions for the ultrafiltration technique were finally determined. It was found that, for the membrane with a cut-off molecular mass of 20000, when the temperature, pressure, time were respectively 40 degrees C, 0.36 MPa, 20 minutes and adding 24L water, yield of Chlorogenic acid was 99.38%.


CONCLUSION
High Chlorogenic acid transfering ratio can be gotten by ultrafiltration technique, which is helpful to the further isolation and purification of Chlorogenic acid in the subsequent process.