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The pattern of serum levels of pregnancy‐associated plasma protein A (PAPP‐A) during the ovulatory menstrual cycle

Summary. Pregnancy‐associated plasma protein A (PAPP‐A) was measured throughout the menstrual cycle in eight women at daily intervals. The protein could be detected in all serum samples, and one patient showed consistently high PAPP‐A values during the entire observation period. Twenty‐six more women were tested by measuring a single serum specimen. No further high PAPP‐A levels were discovered in these. There is no significant difference in PAPP‐A concentration between the follicular and the luteal phase of the cycle.