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Recent Advances in Thrombolysis and Thrombectomy in Acute Ischemic Stroke Treatment: Neurologist’s and Interventional Neuroradiologist’s Perspective

As stroke is still the leading cause of disability and mortality worldwide, it is promising that there has been a significant change in the acute treatment options for the patients presenting with acute ischemic stroke over the last 23 years after the approval of alteplase. Vascular recanalization of the occluded artery by endovascular methods with or without thrombolysis has shown improved clinical outcomes, particularly after randomized control trials (RCTs), which were conducted between December 2010, and December 2014. These trials will be discussed in more detail the below following sections of this chapter. Successful emergency reperfusion conducted on time still remains the most important determinant of good clinical outcome.