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Determinación de la etiología de la infertilidad asociada a trastornos ginecológicos por endometriosis en mujeres en edad reproductiva

Endometriosis is the abnormal growth of endometrial tissue similar to that forming the inside of the uterus, but in a place outside the uterus. Endometriosis is commonly found in other organs of the pelvis; 15% of the cases of female infertility are caused by endometriosis, found in 12% to 32% of women of reproductive age, 50% of women undergoing laparoscopy for infertility and in 50% of adolescents to this procedure for the evaluation of pelvic pain. The objective of this work is to establish the incidence of genetic factors in endometriosis and its main complications based on the analysis of descriptive studies of indexed journals. Results: It was shown that the genotype CYP19A1 rs2899470 with polymorphism is associated with the risk of endometriosis in the population demonstrated by a confidence index of 2. 33. It was also found that the family history of a mother suffering from endometriosis produces a high relative risk in the daughters to generate the same disease with a P = 0.001. The diagnosis and treatment by laparoscopic surgery demonstrated a high effectiveness in the symptomatology of endometriosis was associated with an increase in live birth or in the ongoing pregnancy rate (OR 1.94, 95% CI 1.20 to 3.16, P = 0.007, and increased clinical pregnancy rate (OR 1.89, 95% CI 1.25 to 2.86, P = 0.003