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The safety and availability of blood and tissues--progress and challenges.

The availability of a safe blood supply is critical for both medical progress and national security. Safety has been increased by nucleic acid–amplification testing, as documented by Stramer et al. in this issue of the Journal.1 As health care providers, public health officials, and providers and users of donated blood and tissues we strive to improve the safety of the blood supply and to consider future threats, including threats to the safety of the donated tissue supply. Twenty years ago — with tragic consequences — up to 1 in 100 blood units in the United States transmitted the human . . .