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Viral Load in Epstein‐Barr Virus‐Associated Hemophagocytic Syndrome

The viral load in peripheral blood from patients with Epstein‐Barr virus (EBV)‐associated hemophagocytic syndrome was measured by real‐time quantitative PCR and compared with that in infectious mononucleosis. Patients with EBV‐associated hemophagocytic syndrome generally had larger viral burdens, although it was difficult to differentiate EBV‐associated hemophagocytic syndrome from infectious mononucleosis simply by viral load. The difference in viral load seemed to be clearer in peripheral blood mononuclear cells than in plasma.