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Are There Accurate Predictors for Sentinel Lymph Node Positivity in Patients With Thin Melanomas?

Before that, the risk of an invasive procedure such as sentinel lymph node biopsy was not believed to be necessary for low-risk thin melanomas. We know that a small percentage of these patients go on to develop metastatic disease and ultimately have a poor prognosis. Whether or not sentinel lymph node biopsy will help protect these patients from that fate is debatable. Clearly, a better way to estimate the risk of metastasis for thin melanomas is needed. There has been some suggestion that the depth of invasion by Clark level and/or the nodular subtype discriminates a select group of patients with thin melanomas that might benefit from staging their disease with sentinel lymph node biopsy.