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Decreased T‐regulatory cells are associated with blood pressure elevation and sympathoexcitaton in hypertensive rats (875.10)

Background: Previous reports have suggested that T‐regulatory cells (Tregs) prevent angiotensin II (AngII)‐induced hypertension and organ damage. Abnormal sympathoexcitation is a major factor in the pathogenesis of hypertension. The aim of the present study was to determine whether Tregs are involved in the development of hypertension, and whether blockade of brain AngII type 1 receptors (AT1R)‐induced sympathoinhibition affects Tregs or not.