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Atypical associations between DI*A and DI*B alleles and the band 3‐Memphis mutation in Amazonian inhabitants

The Diego blood group system has a great anthropological and transfusion medicine importance, being associated with immediate, delayed haemolytic reactions and haemolytic disease of new born. Its 22 antigens are located on the integral band 3 glycoprotein, which is encoded by the SLC4A1 gene. We studied the frequency of DI*A, DI*B alleles, band 3 (166A) and band 3‐Memphis (A166G) in individuals from the Brazilian amazon. To investigate atypical associations between DI*A, DI*B alleles, band 3 and band 3‐Memphis.