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Detection of sentinel lymph nodes in gastric cancers based on immunohistochemical analysis of micrometastases

The sentinel lymph node (SN) theory has the potential to change the trend of surgery for gastric cancer that is based on wide resection of the stomach with dissection of regional lymph nodes. However, feasibility tests of SN mapping procedures in gastric cancers with analysis of micrometastasis are rare. This study aimed to estimate the clinical usefulness of SN mapping using a dual procedure with dye‐ and gamma probe‐guided techniques for gastric cancers, based on immunohistochemical staining (IHC) analysis.