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Zero-Filling Interpolation Processing Technique Can Efficiently Suppress Segmental Stenosis Artifact on Small Arteries of Anatomical Phantoms

The purpose of this study was to evaluate the zero-filling interpolation processing (ZIP) technique for contrast-enhanced MR angiography (CE-MRA). Phantoms of arteries were made with different lumen diameters. Gadolinium-enhanced three-dimensional MR angiography was performed on a GE 1.5T scanner. The parameters of FSPGR pulse sequence were: flip angle 30°, TR 6ms, TE 1.4ms, bandwidth 31.25 kHz, slice thickness 1.2 mm, matrix 256×256. The sequence parameters were kept constant for the studies, whereas four selections were chosen: 1) with ZIP1024 and ZIP×4 techniques; 2) only with ZIP1024 technique; 3) only with ZIP×4 technique; 4) without ZIP technique. For image quality evaluation, MR maximum intensity projection (MIP) images were created. Signal-to-noise ratio (SNR) was measured on MIP images. Vessel edge was determined using full width at half maximum (FWHM) for lumen diameter calculation and results were compared with the actual lumen diameter. The distinctness of the vessel edge and the artifacts on the phantoms were compared for all sequences. Three experienced radiologists made consensus evaluation. The FWHM results of lumen measurements for all the sequences with ZIP techniques were more accurate than that of the sequence without ZIP technique in all phantoms, no matter what the size of the artery. The vessel edge with ZIP1024 technique was more distinct. However, the highest average SNR was obtained with the sequence without ZIP technique. The segmental stenosis artifacts on small artery of phantoms were only efficiently suppressed with the ZIP×4 technique. ZIP technique is excellent for CE-MRA to obtain high quality MR angiography. It not only can improve the spatial resolution and the distinctness of the vessel edge on CE-MRA, but can also efficiently suppress segmental stenosis artifact on small arteries of phantoms.