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Complex Treatment of the Patients with Alzheimer?s Disease Using Stem Cell Preparations Including Extracted Fetal Stem Cells

Objective: The principal aim of this study was to evaluate effectiveness of combined therapy method with 
 inclusion of the standard protocol of treatment using medicines along with application of separated fetal stem cells (FSCs). Higher efficacy of treatment of the patients with Alzheimer’s Disease (AD) is defined as a technical value of 
 our complex therapy. 
Material and Methods: We performed a comparative study of the groups of patients including women and men 
 aged from 50 to 85 years who were presented with diagnostic criteria of Alzheimer’s type dementia by DSM- IV-TR, 
 NINCDS-ADRDA as well as study of the patients with confirmed diagnosis of AD in accordance with ICD-10-CM 
 suffering from mild and moderate-to-severe stages of dementia by CDR and MMSE scales. Along with standard 
 treatment by use of stable doses of medicines our patients were administered FSCs suspensions containing stem 
 cells extracted from the tissues of fetal liver and brain (human cadaveric fetuses of 7-12 weeks gestation) which were 
 acquired as a result of medical abortion due to social and family planning reasons. 
Results: In a process of the comparative study the results we received emphasize treatment significance and 
 advantages of complex therapy method compared to standard treatment used as isolated therapy for AD patients 
 suffering from mild-to-moderate dementia. The suggested method of complex treatment is safe and contributes to 
improved cognitive functions as well as increased daily activities among such a group of AD patients (p<0.05). 
Conclusion: Use of preparations with extracted FSCs in complex treatment of the AD patients with mild and 
 moderate grades of dementia has been proven to be safe and effective method of therapy which contributed to better cognitive functions and increased everyday activity among patients with AD.