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HTLV‐1‐associated cutaneous disease: a clinicopathoiogical and molecular study of patients from the U. K.

The clinieopathological features of eightpatients with cutaneous disease associated with HTLV‐1 infection are reviewed. All were U. K. residents of West Indian extraction, and two are currently alive. Disease remained confined to the skin in two patients. Five patients with a cutaneous prodromal phase developed leukaemia after a medianduration of 124 months (3months‐21years), and in one of these combination chemotherapy produced a sustained clinical remission for 20 months. Two patients developed cutaneous disease after remission of their leukaemia.