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Intracellular calcification: an unusual histological feature of acute myocarditis

On post-mortem examination, the significant finding was in the heart. It was flabby and weighed 290 g. The coronary arteries were widely patent and the cardiac valves were normal. There was no evidence of acute myocardial infarction. Microscopy revealed multiiocal patchy infiltrates of lymphocytes and histiocytes in both ventricles, associated with individual myocardial cell necrosis. Contraction band necrosis was seen in some of the adjacent myocardial fibres (Figure la). Examination of the cardiac conduction system showed involvement of the left bundle branch by patchy infiltrates of small lymphocytes, associated with myocytolysis of the conduction fibres (Figure lb).