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Effects of different postoperative analgesia methods on T cells subgroups after lower adbominal surgery

Objective To study the effect of postoperative analgesia method on patient's T cells subgroups after lower abdominal surgery,and to explore protection immunity of epidural analgesia.Methods Fifty patients,ASA grade Ⅰ～Ⅱ,who would undergo lower abdominal surgery,were divided into two groups.Group I were given analgesic drugs by vein injection.The degrees of postoperative pain in both groups were compared.The peripheral blood samples of both groups were compared.The peripheral blood samples of both groups were obtained before anesthesia(T1),at the end of operation(T2),on the first day(T3)and the third day after operation(T4)to determine T cell subgroups.Results VAS score was obviously lower in group I compared with group Ⅱ.CD4+ and CD4+/CD8+ at T2,T3 were obviously decreased compamed with T1(P0.05)in two groups.CD4+ and CD4+/CD8+ at T2,T3 in group I were remarkably decreased compamed with Group Ⅱ(P0.05).CD8+ in two groups had no change.Conclusion PCEA is a better postoperative analgesia method after lower abdominal surgery,which has a better immunity protection.