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Congenital Muscular Dystrophy

Congenital muscular dystrophy is one of the variants of muscle weakness disorders presenting early in life during infancy and soon after birth. The difference between congenital myopathies and muscular dystrophies is that dystrophies are gradually progressive and are associated with increased muscle breakdown with age. Congenital myopathies signify disorders associated with muscle weakness in the neonatal age group, which could be secondary to genetic, metabolic, or other disorders and usually have a non-progressive course. Classification of these groups of disorders is based on findings on muscle biopsy and genetic evaluation. The muscle biopsy findings common for these disorders are muscle fiber atrophy, fibrofatty infiltration of tissue.