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Two cases of leukocytoclastic vasculitis with tuberculosis

Leukocytoclastic vasculitis is characterized by a palpable purpura showing microscopically necrotizing vasculitis of the small dermal blood vessels. The cause has been considered to be a deposition of immune complexes under conditions of slight antigen-excess. Infections are proposed to be a causative factor and leukocytoclastic vasculitis due to Mycobacterium tuberculosis has been reported previously 2–5 but is uncommon. We describe two cases of the condition associated with tuberculosis. The association with M. tuberculosis was identified by the polymerase chain reaction (PCR) and response to antituberculous therapy.