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Lipid, inflammatory and haemorheological profiles are significantly affected by farmed fish eating: an intervention study

Aim The objective of the present study was to evaluate the influence of short-term dietary intake of farmed fish on biomarkers related to the atherosclerotic process. Methods and results Lipid, inflammatory, and haemorheological variables before (T0) and after a dietary intervention with about 800 g Orbetello farmed sea bass per week for 10 weeks (T1) were evaluated in nine dyslipidemic subjects. Fish intake significantly decreased triacylglycerols (T1, 140.2±20.3 mg/dl versus T0, 183.3±29.2 mg/dl; P =0.04), whereas no significant changes for the other lipid variables have been observed. Moreover, dietary intervention significantly (P <0.05) decreased all of the inflammatory parameters investigated; namely, high-sensitivity C-reactive protein, interleukin-6, and interleukin-8. Furthermore, a significant (P =0.04) improvement in erythrocytes’ deformability index was reported after 10 weeks of fish dietary intake (9.0±0.7% versus 5.4±1.0% for T1 and T0, respectively). Conclusion Dietary short-term intake of farmed fish seems to impose favourable biochemical changes in dyslipidemic subjects.