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Review on Analytical Methods for Estimation of Itraconazole in Bulk and Pharmaceutical Dosage Form

Itraconazole is an orally administered, trizole antifungal agent used in the treatment of systemic and superficial fungal infections. This includes infection in any part of body including the lungs, mouth or throat, toenails or fingernails. Some brands of itraconazole are not for use in treating fungal infections of the fingernails or toenails. Itraconazole has antimycotic properties. Formulated for both topical and systemic use.The objective of this review is to present summary and compilation of various research papers, which were already published in different national and international literature platform for estimation of itraconazole in bulk and pharmaceutical formulations with special emphasis on UV spectrophotometric and high performance liquid chromatography (HPLC) methods. There are various parameters used with UV Spectrophotometric and HPLC method, but few significant parameters are λmax, solvent for UV Spectrometric method and stationary phase, mobile phase, retention time, column in case of HPLC. This compilation review presents all the analytical methods which were already used for estimation of itraconazole with their important parameters, which will be beneficial for the researchers and add to the existing literature in this field.