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Lead and multiple sclerosis.

It has been suggested that lead may be a cause of multiple sclerosis, but confirmation of this hypothesis is difficult to obtain as lead is so widely present both in the environment and in many human tissues.In this study 22 patients with multiple sclerosis were compared with 22 controls. Lead levels in the blood of the patients were not higher and urinary lead levels in the patients before and after a single dose of penicillamine did not provide evidence to support the hypothesis that lead may cause the disease.