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Autoimmune response and myocarditis associated with COVID-19 vaccination

Recently, there have been numerous reports of suspected myocarditis cases following vaccination against Corona Virus Disease 2019 (COVID-19), although the exact mechanism behind it is still unclear [1,2]. Shaw KE and colleagues reported four cases of acute myocarditis that were temporally related to the receiving of COVID-19 vaccine based on their Cardiac Magnetic Resonance (CMR) imaging findings [3]. Among them, two patients with previous COVID-19 infection developed symptoms after the first dose, while the other two patients with no previous COVID-19 infection developed symptoms after the second dose. Therefore, the authors argued that there might be a potential immune-boosting mechanism flowing prior immune exposure or priming.