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Can human embryos resulting from Somatic Cell Nuclear Transfers (SCNT) be used to treat human infertility? future implications in Assisted Reproductive Technologies (ART)

For future advancements in reproductive cloning, it will be important to further increase our experience and knowledge about how to rejuvenate and reprogram human adult cells by modern molecular and cellular biotechnology.19 In this context, we have started a novel approach using two different types of adult human cells (granulosa cells from female patients enrolled in IVF programs and fibroblast cells from infertile male patients) for SCNT into enucleated bovine oocytes.20,21 Development of such a cloning biological model enables us to utilize it as a bioassay to test and compare the efficiency of different human adult somatic cells for their ability to promote embryonic development via interspecies SCNT.