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Minocycline-induced autoimmune hepatitis with subsequent cirrhosis.

Minocycline is an antibiotic commonly used in the treatment of acne vulgaris. It is known to have adverse side effects such as hypersensitivity reactions, gastrointestinal intolerance, serum–sickness-like reaction, single organ dysfunction, benign intracranial hypertension, pneumonitis, and autoimmune hepatitis. In general, recovery from autoimmune hepatitis has been said to be good after discontinuation of minocycline. Our case represents a young man who was treated with minocycline for acne and developed drug-induced autoimmune hepatitis and cirrhosis.