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The plant protein 'package' may be preferred in high-protein diets.

Dietary interventions have established that highprotein diets can induce weight loss. As reviewed [1 ], several of the popular high-protein diets are high in fat. Most investigations of high-protein diets, including a recent study [2 ], have relied primarily on animal sources of protein as indicated by typical menus [1 ] and reported high content of cholesterol and saturated fat [2 ]. The high content of cholesterol and saturated fat in popular high-protein diets raises concerns regarding the long-term impact of such diets on cardiovascular disease as well as other chronic diseases. Importantly, no randomized, controlled clinical trial has demonstrated the long-term safety of high-protein diets. Just as the long-term safety of high-protein diets remains to be established, the long-term impact of the source of dietary protein remains to be determined. However, accumulating evidence suggests that plant proteins, particularly legumes, may be valuable components of high-protein diets.