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Antioxidative and Allergic Profile in Adult Men with Cigarette Smoking

Accumulating experimental and epidemiologic data suggest that smoking is a central factor in many pathological conditions. The aim of this study was to determine if total antioxidant capacity (TAC) is related with serum Imonoglobin E (IgE) in cigarette smokers. For this purpose, serum IgE and TAC were measured after an overnight fast in adult males (n=30, age 41±4 yrs, body weight 89±4.9 Kg) with a history cigarette smoking at least for 3 years. Pearson’s correlation coefficients were used to evaluate the correlation between them. A p-value < 0.05 was considered to be statistically significant. Data showed a significant negative correlation serum IgE with TAC in studied subjects (P=0.011). These findings suggest that antioxidant system can be affect by IgE as an allergic agent in smokers.