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Karyotyping, is it worthwhile in transsexualism?

INTRODUCTION
Karyotyping is often performed in transsexual individuals.


AIM
Quantification and characterization of karyotype findings and abnormalities in transsexual persons.


MAIN OUTCOME MEASURES
Karyotypes were listed both in male-to-female and in female-to-male transsexual persons.


METHODS
The data were collected through a retrospective study.


RESULTS
Karyotypes of 368 transsexual individuals (251 male-to-female, 117 female-to-male) are described. Normal findings were found in 97.55%. Prevalence of abnormal karyotypes was 3.19% among male-to-female, and 0.85% among female-to-male transsexuals. Nine karyotypes showed variations; Klinefelter syndrome was confirmed in three persons, whereas others displayed autosomal aberrations.


CONCLUSION
Karyotyping is only of very limited information in the transsexual population.