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The evolution of pain in knee osteoarthiritis treatment with sodium hyaluronate

Abstract Although the knee osteoarthritis is often benign, severe degenerative modifications can determine serious malfunction. In joints affected by arthritic processes, Sodium hyaluronate is found in reduced concentrations, the normal articular cartilage being replaced by fibrocartilage [6]. The present concepts suggest that osteoarthritis is not a predictable stage in ageing and prophylactic and therapeutic approaches could be taken in the future