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Penicillinase as a potential enzyme marker for enzyme linked immunosorbent assay and its application in immunodiagnostics.

The present review article deals with the application of penicillinase in enzyme linked immunosorbent assay (ELISA) and describes the various characteristics of penicillinase. Using penicillinase as an enzyme marker, few kits have been developed to detect physiologically active proteins, infectious diseases and toxins. The review also highlights briefly the source of penicillinase, its production, isolation, purification and certain molecular properties.