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The outcome of 48 renal transplantations immunosuppressed with cyclosporine-A as monotherapy.

The course of 48 consecutive cadaveric renal transplantations immunosuppressed with Cyclosporine-A (CyA) as monotherapy in 3 different doses was retrospectively analysed. CyA doses were based on clinical observations. Overall one-year graft survival was 52% and for grafts immediate diuresing 82%. A dosage schedule of 12 mg CyA/kg/day seemed to secure graft function without any side effects to the patient.