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Effects of Triazines on Energy Relations of Mitochondria and Chloroplasts

The effects of eight s-triazines on respiration of (Phaseolus vulgaris L. ‘Black Valentine’) bean and rat liver mitochondria and on cyclic photophosphorylation of pea (Pisum sativum L. ‘Thomas Laxton’) chloroplasts were determined. All triazines inhibited state 3 respiration and cyclic photophosphorylation. The degree of inhibition was similar in both rat liver and bean mitochondria. Prometryne [2,4-bis-(isopropylamino)-6-(methylthio)-s-triazine] was the most potent inhibitor of both respiration and cyclic photophosphorylation. Triazines with the methylthio group showed the most activity, followed by those with the methoxy and chloro substituents in that order.