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Fluorescent fibre‐optic confocal characterization of in vivo epidermal changes in atopic eczema

Fibre‐optic confocal imaging (FOCI) allows non‐invasive visualization of live skin in vivo. A contrast agent, a fluorophore, is injected into the dermis. FOCI images are horizontal optical sections with cellular resolution. The aim was to study in vivo epidermal changes and the cellular structure of keratinocytes in moderate to severe atopic eczema (AE).