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Self‐limited lupus‐like presentation of human parvovirus B19 infection in a 1‐year‐old girl

Human parvovirus B19 (HPV-B19) is a DNA virus of the erythrovirus, and causes erythema infectosum, arthritis, and transient marrow aplastic shock, while systemic lupus erythematosus (SLE) is a chronic, multisystem autoimmune inflammatory disease of unknown cause, which may involve the skin, joints, kidneys, lungs, and central nervous system. We report the association of prolonged fever, migrating skin rash, and edema of hands and feet with hypocomplementemia and hypoalbuminemia in a 1-year-old girl with HPV-B19 infection. Kawasaki disease should be distinguished from this clinical condition, and this is the earliest case of SLE-like presentation with HPV-B19 infection.