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The frequency of hyperuricemia with left ventricular hypertrophy in patient with primary hypertension in Erbil city-Iraq

Background: High serum uric acid level is common in hypertension and it may be correlated with left ventricular hypertrophy. The frequency of hyperuricemia is not previously well investigated in Erbil city. Objectives: The objective of this study was to investigate the frequency of hyperuricemia and the association between serum uric acid levels and left ventricular hypertrophy in a group of hypertensive patients in Erbil-Iraq. Patients and methods: A cross-sectional study was conducted in Rizgary teaching hospital between September 2015 and September 2016. A total of 150 consecutive adult patients presenting with primary hypertension were included. Based on the results of the echocardiography, the patients were classified into two groups; Group I (patients with left ventricular hypertrophy) and Group II (patients with nonleft ventricular hypertrophy). The effects of high serum uric acid level on left ventricular mass and geometry were evaluated in both groups. Results: High serum uric acid level was present in 38 patients (25.3%). Based on the results of echocardiographic examination, left ventricular hypertrophy was present in 78 patients (52%), 25 of them (32 %) had hyperuricemia. The mean of serum uric acid level, means of age, systolic blood pressure, diastolic blood pressure and lipid profile significantly higher in group I patients compared to those in group II patients. Regarding echocardiographic parameters, There were significantly higher in hyperuricemic patients compared to patients without hyperuricemia the means of interventricular septal thickness, left atrium and left ventricular mass. Conclusions: In this study, high serum uric acid level was common in hypertensive patients and it was positively associated with left ventricular hypertrophy and dyslipidemia. A r t i c l e i n f o. Article history: -Received 22/4/2017 -Accepted 26/6/2017 -Available online: 2/1/2019