{'fraction_non_alphanumeric': 0.02159090909090909, 'fraction_numerical': 0.0, 'mean_word_length': 5.118055555555555, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Effect of ethanol on cardiac beta-adrenoceptors.

Liquid diets are commonly used as vehicles for chronic administration of ethanol to rodents. After mice had consumed an ethanol-free liquid diet for either seven or eight days, the number of cardiac beta-adrenoceptors and the maximum response of adenylate cyclase to isoproterenol were decreased. This change was associated with a decrease in the number of high-affinity agonist binding sites. When mice were fed ethanol in the liquid diet, there was a further decrease in the number of cardiac low-affinity agonist (isoproterenol) binding sites, but no further change in the biochemical response to isoproterenol. The data suggest that stress and/or nutritional factors can alter the number, the coupling and the function of cardiac beta-adrenoceptors and that chronic ethanol ingestion enhances certain aspects of these changes.