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Sequence Analyses of the Representative Chinese-Prevalent Strain of Avian Nephritis Virus in Healthy Chicken Flocks

Important Findings Avian nephritis virus (ANV), which belongs to the Astroviridae family, has been associated with acute nephritis in chickens. Cases of ANV infection have been recorded in Japan and in several European countries. However, related studies have never been performed in China. Thus, this study isolated ANV in Chinese chicken flocks. Comparative and phylogenetic analyses based on partial RNAdependent RNA polymerase (ORF1b) demonstrated that the majority of ANV investigationed were more closely related to the U.S. ANV strain (DQ324827–324836) than to G-4260 (AB033998).