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Nickel sensitivity and the course of atopic dermatitis in adulthood

The course of dermatitis was followed in nickel‐sensitive and nickel‐negative atopic and non‐atopic patients. Manifest dermatitis was seen in 70% of the nickel‐allergic and in 64% of the nickel‐negative female atopic dermatitis (AD) patients. Those atopic subjects who had minor symptoms in their teens suffered more from dermatitis if they had developed nickel allergy (p < 0.025). Hands and the head region were the most common sites for current dermatitis in both groups.