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[Postoperative cognitive dysfunction.].

Ever since Bedford’s seminal Lancet case series in 1955, we have known that perioperative care is sometimes followed by significant cognitive dysfunction. Although the safety of perioperative care has improved dramatically since 1955, the descriptions of cognitive dysfunction in that case series are eerily similar to the complaints of current patients suffering from postoperative cognitive dysfunction (POCD). POCD remains a common postoperative complication associated with significant