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Morphological characterisation of glial and neuronal tau pathology in globular glial tauopathy (Types II and III)

Globular glial tauopathy (GGT) is a new category within the 4‐repeat tauopathies that is characterised neuropathologically by tau‐positive globular glial inclusions (GGIs), namely, globular oligodendrocytic and astrocytic inclusions (GOIs and GAIs). Occurrence of tau‐positive neuronal cytoplasmic inclusions (NCIs) is also a feature. GGT is classified into three pathological subtypes (Types I, II and III). We studied the tau pathology in 6 cases of GGT (Type II, n = 3; Type III, n = 3), with special reference to GAIs and NCIs.