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Complications and survival of multilumen central venous catheters used for total parenteral nutrition

In a prospective study of 879 triple‐lumen catheters, 219 pulmonary artery catheters, 31 double‐lumen and six single‐lumen catheters used for the administration of total parenteral nutrition over a 1‐year period, the overall complication rate was 12‐5 per cent (14‐7 complications per 1000 catheter‐days) and the catheter‐related sepsis rate 4·4 per cent (5·2 per 1000 catheter‐days). The probability of development of catheter‐related sepsis did not increase with the duration of catheterization. There were no differences in the rate of complications associated with 427 catheters changed by replacement at a new site compared with 159 lines changed over a guidewire. These data support the use of multilumen central venous catheters for the administration of total parenteral nutrition. They suggest that a routine weekly change of line is unnecessary; catheters should be changed only on the development of a complication. When it is required, a catheter should be changed by replacement over a guidewire.