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Inhibition of Candida albicans by the anaerobic oral flora of mice in vitro.

Candida albicans was grown anaerobically for 30 h in cultures of anaerobic bacteria isolated from the oral cavity of mice, in anaerobic flora culture filtrates, and in sterile broth as controls. In mixed cultures, C. albicans entered into a logarithmic death phase, while Candida cells grown in culture filtrates remained in a prolonged lag phase. C. albicans grown anaerobically in sterile broth produced a gradual increase in growth.