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TRIMETHYLAMINE‐N‐OXIDE REVERSES AUTOPHAGIC DYSFUNCTION IN THE LUNG TISSUES OF OVA‐OVA BRONCHIAL ASTHMA MICE

of RSS were significantly increased only in the ACO group compared with the other groups. The levels of RSS in the sputum were significantly decreased in the ACO group compared with the other groups. The amounts of IL-8 and MCP-1 were significantly increased in the ACO group compared with the other groups. Furthermore, the nitrosative stress markers and the levels of RSS were significantly correlated with the data of lung function. Conclusion: These results suggest that imbalance of oxidants/antioxidants occurred in the airways of patients with ACO and it might be related to the pathogenesis.