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Intraocular Lens Opacifications in Descemet Stripping Endothelial Keratoplasty Patients

Purpose: To report 3 cases of unexplained intraocular lens (IOL) opacification in patients who previously underwent Descemet stripping endothelial keratoplasty (DSEK). Methods: Case series. Three pseudophakic eyes of 3 patients, who developed a membraneous opacification of the IOL after uneventful DSEK are presented. Results: In 2 eyes, the opacification interfered with visual acuity. In 1 case, an attempt was made to remove the opacification with the aid of YAG laser and surgically, to no avail, necessitating an IOL explantation. Conclusions: IOL opacification can occur in eyes previously subjected to DSEK. The majority of patients subjected to DSEK are pseudophakic; surgeons should be aware of this possible complication. To the best of our knowledge, this has not been described in the literature to date. Further research is required to elucidate the nature of such IOL opacifications and possible ways to prevent them.