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Studies on the Occurrence of Cryptococcal Meningitis in Small Animals:Untersuchungen zum Vorkommen von Cryptococcus‐Meningitis bei kleinen Tieren

Summary: The prevalence of cryptococcal meningitis has been investigated in 39 animals which comprised 36 dogs, 2 monkeys and 1 cat. Cryptococcus neoformans was isolated from the infected brains of 2 dogs on mycological media. The pathogen was also demonstrated in the brain tissues of the animals by potassium hydroxide technique. The histopathological examination revealed liquefaction of the brain surrounded by gliosis and a large number of yeast‐like cells with or without budding compatible with Cryptococcus neoformans. The disease could not be recorded from monkeys and the cat. The epidemiological investigation helped to establish the source of infection pigeon dropping in one ten year old male dog who was kept as watch animal in a poultry farm in Delhi. The isolates of Cryptococcus neoformans recovered from the clinical as well as environmental materiais were found to be pathogenic to swiss albino mice. It has been emphasized that cryptococcosis should be considered in the differential diagnosis of meningitis in small animals particularly canine.