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Recurrent unexplained haematuria and risk of urological cancer. A follow-up study.

To evaluate the risk of urological cancer in patients with unexplained haematuria, 93 patients, who had undergone complete urological examination and who were classified as having unexplained haematuria, were followed. Mean age was 46 years, range 16-84 years. Seventy-seven patients had gross haematuria and 16 patients had microscopic haematuria. Mean follow-up time was 62 months (range 6-360 months). Urological neoplasms were found in 7 of 38 patients (18%; 95% confidence limits 8-34%) with recurrent haematuria after primary urological examination, and in 1 of 36 patients (3%; 95% confidence limits 0.07-14%) without additional haematuria after primary examination. Regular urological examination of patients with recurrent unexplained haematuria is justified. In patients without additional incidents of haematuria after primary urological examination the risk of urological cancer is not significantly increased.