{'fraction_non_alphanumeric': 0.03856749311294766, 'fraction_numerical': 0.009641873278236915, 'mean_word_length': 6.058252427184466, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Palladium-Catalyzed Cycloaddition of Alkynylimines, Double Isocyanides, and H2O/KOAc.

In this work, a palladium-catalyzed cyclization of alkynylimines and double isocyanides is described. This facile procedure is efficient for synthesizing various 4-amidyl-2-aminopyrroles. Mechanism investigation indicates that a four-membered ring-fused pyrrole species is a key intermediate and the reaction involves [4+1] cycloaddition, protonation, nucleophilic addition, 1,4-addition of isocyanide, and re-aromatization. Interestingly, the linear dipyrrole derivative is found to be an appropriate fluoride ion probe with a remarkable emission change, which could serve as a potential candidate for optoelectronic conjugated materials.