{'fraction_non_alphanumeric': 0.015918958031837915, 'fraction_numerical': 0.005788712011577424, 'mean_word_length': 5.681159420289855, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Session on Neuromuscular Disorders Afternoon Meeting Friday, April 29,1977

Recent studies from this laboratory have indicated that the visual association cortex, acting via the lateral geniculate body, serves to facilitate penicillin-induced discharges in the visual cortex. The present investigation was undertaken to evaluate the influence of other cortical areas on penicillin discharges limited to striate cortex. Studies were conducted on unanesthetized adult cats subjected to an intercollicular transection of the brain stem. Penicillin discharges were established in the left striate cortex, and when a stable discharge frequency was obtained, other discrete cortical areas were cooled to 15°C. producing a reversible functional block. Changes in penicillin-discharge frequency, when evident, were statistically evaluated. Direct cooling of the involved striate cortex markedly reduced seizure activity. Significant reduction in seizure activity was also seen with cooling of contralateral striate cortex, as well as with cooling of ipsilateral and contralateral visual association cortex. None of the other cortical areas tested produced a reproducible effect on the seizure frequency. These findings support the hypothesis that the activity of a seizure focus is a function not only of local factors but of input from both subcortical structures and other cortical areas.