{'fraction_non_alphanumeric': 0.028694404591104734, 'fraction_numerical': 0.011477761836441894, 'mean_word_length': 5.8431372549019605, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Catalytic Asymmetric Conjugate Addition of Borylalkyl Copper Complex in Chiral Organoboronate Synthesis.

We report the catalytic enantioselective conjugate addition of borylalkyl copper nucleophile generated in situ from 1,1-diborylmethane to α,β-unsaturated diesters under mild conditions. In the presence of a chiral N-heterocyclic carbene (NHC)-copper catalyst, this method facilitates enantioselective incorporation of -CH2Bpin moiety into the β-position of the diesters, yielding β-chiral alkylboronates with up to 86% yield and 98:2 enantiomeric ratio. The resulting chiral alkylboron diester products were converted into various functional groups by organic transformation of the C-B bond.