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Radiographic manifestations of primary acquired hypogammaglobulinemia.

Abstract Radiographic examinations of 24 patients with primary acquired hypogammaglobulinemia were reviewed. Although all patients had chest examinations, the extent of other radiographic studies varied. Acute and/or chronic lung changes with obstructive lung disease, occasionally associated with bronchiectasis, were found in almost all cases. Most patients had sinusitis and more than half had splenomegaly. Small bowel changes included thickening of the valvulae conniventes or lymphonodular hyperplasia. Since lung disease, sinusitis, and splenomegaly were found in the majority of the patients, this combination of findings is presented as an occasionally useful triad in the diagnosis of primary acquired hypogammaglobulinemia.