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Measurement of Urinary Sugars by HPLC Evaluation in Pediatric Clinical Practice

mono- and disaccharides,respectively. The resultsofthe permeability tests were compared with those of intestinal biopsy in 20 children. All patients with an abnormal intestinal biopsy showed a low mannitol recovery, and the patients with allergic symptoms showed a high lactulose recovery. Our preliminary data suggest that HPLC is reliable, gives results comparable with those of other methods, and is a practical way to determine intestinal permeability noninvasivety.