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Myeloma: unusual cause of exophthalmos. An angioarchitectural study.

The solitary or multicentric myeloma is an uncommon cause of exophthalmos. The angioarchitectural features found in these cases include subtle, increased vascularity, a rather homogeneous tumor stain, possible minute tumor vessels, rapidity of circulation, and involvement of meningeal vessels. The stain may be intimately related to the abnormalities of bone. The recognition of this lesion requires further investigation to exclude systemic disease. The lesion resulting in exophthalmos may be treated by irradiation to obviate surgery.