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Sacral nerve stimulation induces pan‐colonic propagating pressure waves and increases defecation frequency in patients with slow‐transit constipation

Objective  Colonic propagating sequences are important for normal colonic transit and defecation. The frequency of these motor patterns is reduced in slow‐transit constipation. Sacral nerve stimulation (SNS) is a useful treatment for faedcal and urinary incontinence. A high proportion of these patients have also reported altered bowel function. The effects of SNS on colonic propagating sequences in constipation are unknown. Our aims were to evaluate the effect of SNS on colonic pressure patterns and evaluate its therapeutic potential in severe constipation.