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Exercise improves adiposopathy, insulin sensitivity and metabolic syndrome severity independent of intensity

What is the central question of this study? What are the effects of work‐matched continuous versus high‐intensity interval training for 2 weeks on adiposopathy and cardiometabolic risk in obese adults with prediabetes? What is the main finding and its importance? Independent of intensity, short‐term exercise improves adiposopathy and insulin sensitivity. While both exercise intensities reduced fasting leptin concentrations and metabolic syndrome severity, only interval training elevated total adiponectin. In contrast to previous work, neither condition altered high‐molecular weight adiponectin. Collectively, these data suggest that short‐term exercise can improve adipokine profiles, which may aid in reducing cardiometabolic risk prior to clinically meaningful weight loss in adults with prediabetes.