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Eighth Australian and New Zealand Intensive Care Society Meeting

There are a number of significant changes in pulmonary function after cardiopulmonary bypass. The varying postulates may have, as a final common pathway in causation, an increase in extravascular lung water (EVLW), that is, pulmonary oedema. To test this hypothesis we measured the changes of EVLW before, immediately after, and twenty-four hours after a period of extra-corporeal circulation for cardiac surgery. EVLW was measured by the double indicator dilution technique, with calculations being performed by the Edwards 93 IO lung water computer. The indicators used were heat and indocyanine green. Fourteen patients were studied, undergoing surgery for coronary artery bypass grafting; with bypass being conducted with an Optiflow 1I bubble oxygenator. The results of the study refuted the hypothesis that an increase in EVLW in the post-bypass period could account for the changes in pulmonary function after extracorporeal circulation with a bubble oxygenator. Further, that there was no relationship between EVL Wand gas exchange parameters. Finally, because of the technical difficulties with the method useful data were obtained in only eight out of the fourteen patients.