{'fraction_non_alphanumeric': 0.046511627906976744, 'fraction_numerical': 0.027906976744186046, 'mean_word_length': 5.7265625, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Cluster‐10 lung‐cancer antibodies recognize NSPs, novel neuro‐endocrine proteins associated with membranes of the endoplasmic reticulum

We have identified a novel gene (the NSP gene) encoding 3 transcripts and coding for 3 neuroendocrine‐specific proteins (NSPs), by screening a cDNA expression library of the small‐cell lung‐cancer (SCLC) cell line NCI‐H82 with the cluster‐10 lung‐cancer antibodies RNL2 and RNL3. The 3 transcripts code for NSPs with apparent molecular weights of 135 kDa (NSP‐A), 43 to 45 and 35 kDa (NSP‐B) and 23 kDa (NSP‐C). NSP‐A and NSP‐B are recognized by antibodies RNL2 and RNL3, while second‐generation antibodies, specifically recognizing NSP‐A and NSP‐C, have been produced after immunization with a hybrid protein obtained after bacterial expression of the largest NSP‐transcript or with a synthetic peptide specific for NSP‐C.