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Eotaxin but not MCP−3 induces eosinophil influx into nasal fluid in allergic patients

Background: Eotaxin and MCP‐3 (CC chemokines), owing to their preferential action on eosinophils, seem to be the very importance in the patophysiology of allergic rhinitis and asthma. The purpose of this study was to examine the effect of intranasally administered eotaxin and MCP‐3 after specific allergen priming on the influx of inflammatory cells and their soluble mediators into the nasal mucosa.