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A case of non-chromaffin paraganglioma presenting in pregnancy as a dumb-bell tumour.

The chemoreceptor system consists of groups of cells situated in close proximity to major blood vessels which act as the receptor elements involved in a reflex concerned with regulation of blood pressure and respiration. These cells are sensitive to changes in the hydrogen ion concentration, and the partial pressures of oxygen and carbon dioxide in the blood. They have a rich blood supply and sensory nerve connections. The major groups of these cells are found close to the carotid artery, the jugular vein and the aorta, but cells of this type are also found in relation to the vagus nerve and there are several other smaller glomera in the body. Tumours of these cells give rise to chemodectoma or non-chromaffin paraganglioma, which are comparatively rare. The most common site is in relation to the carotid body where about 600 cases have been reported. Mediastinal chemodectomas are much less common and up to 1969 only 28 cases had been described. The purpose of this paper is to describe one of these tumours ...