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Drugs in pregnancy - a prospective study.

A prospective study starting with 1182 women in the early stage of pregnancy investigated prescribed drug therapy; self-medication; consumption of coffee, cigarettes, and alcohol; and a series of social and sociologic factors. The main results are as follows: compared with international reports, drug consumption during gravidity was low. During the first weeks of gravidity, 11% of the women took drugs. Drug consumption increased during gravidity, reaching a maximum of 26% of the pregnant women taking drugs. Drugs most frequently prescribed were antiemetics, analgesics, sedatives, iron preparations, and vitamins. Self-medication (1 or 2%) was extremely low; in most cases analgesics were used. Coffee consumption declined, particularly during the last trimester; consumption of cigarettes showed a distinct decrease from 27% to 12%.