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Development of a novel compression tester and rheo-mechanical properties of wet-mass powder. II--Effect of moisture content on the rheo-mechanical properties.

In our previous paper [Watano S., et al., Chem. Pharm. Bull., 51(7), 747-750 (2003)], a novel compression tester, which enables the vertical and radial pressure transmission measurement, has been developed and quantitative analysis of rheo-mechanical properties of wet-mass powder prepared by different kneading times was conducted. In this study, the compression test was conducted by using the kneaded wet-mass powders prepared by different moisture contents. Pressure transmission characteristics and rheo-mechanical properties have been investigated to characterize the wet-mass powders. The relationship between these parameters and granule physical properties was also investigated.