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Polypoidal choroidal vasculopathy in Caucasian patients with presumed age-related macular degeneration

We read with interest the article by Hatz and Prunte1 describing the frequency of polypoidal choroidal vasculopathy (PCV) among Caucasian patients treated for presumed age-related macular degeneration (AMD). We wholeheartedly agree with the authors that differentiation between PCV and choroidal neovascularisation secondary to typical AMD at initial clinical presentation is important, because this distinction may alter the management decisions and influence the eventual visual outcome.

While the prevalence of PCV in this study is generally higher than those previously reported in Caucasian populations, it is possible that the frequency of PCV in this series may have been even higher if indocyanine green angiography (ICGA) had been performed at baseline. In this study, the authors included patients who were evaluated with ICGA only after receiving ≥8 ranibizumab injections. Prior to evaluation with ICGA, the patients who were eventually diagnosed with …