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Therapy of prostatic cancer and histopathologic follow‐up

The histopathologic follow‐up of local tumor regression of prostatic cancer under hormonal treatment or following high‐voltage therapy is an objective standard to determine a therapeutic success. This report involves 308 patients, who were continuously controlled by serial biopsies, 1, 138 punch biopsies, and 155 TURs from 1971 to 1981. On an average, there are 4.2 biopsies of each patient. The patients were treated with estradiol. They were divided into two groups by histologic classification: 1) adenocarcinomas with large and small acinar pattern (130 cases) and 2) carcinomas with cribriform and/or solid pattern, partly mixed with other glandular types (178 cases).