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Meat Science and Muscle Biology 230 Conjugated linoleic acid ( CLA ) concentrations in beef tissues from cattle finished on pasture initially with limited grain

from 10d to 15d (P<.01), indicating onset of lactation. Megalin expression increased about 3-fold from 0d to 5d (P=.01), then decreased 2.8-fold by 10d (P=.01). Gene expression of LDL-R decreased 4.5-fold (P<.06) from 5d to 10d while folic acid receptor mRNA decreased about twofold (P<.05). We conclude that temporal changes in expression of megalin, LDL-R and folic receptor mRNA during colostrogenesis may be related to the transport of their ligands into colostrum. Hormonal induction of lactation provided a useful model for studying the regulation of colostrogenesis.