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AB1419-HPR Clinic of pregnancy and rheumatic diseases: epidemiologic characterisation

Background Pregnancy in women with Rheumatic Diseases (RD) is of high risk and requires a close communication between the rheumatologist, obstetrician, and all other specialists involved.It may have an effect on the natural history of autoimmune disease, a phenomenon that is particularly relevant in Systemic Lupus Erythematous (SLE) and Rheumatoid Arthritis (RA). Additionally, there are consequences that autoimmune disease may yield throughout the course of conception and gestation. Objectives To describe the epidemiological characteristics of patients seen at the Clinic of Pregnancy and Rheumatic Diseases (Clínica de Embarazo y Enfermedades Reumáticas, CEER) located in the Jose E. Gonzalez University Hospital in Mexico. Methods We conducted a descriptive transversal study of a cohort of 50 adult patients that attended CEER; which were categorised within three consultation groups (reproductive age, with a present or future desire to become pregnant, pregnant or in postpartum period). All patients were evaluated by the Maternal-Fetal Medicine and Rheumatology department. CEER was created in, August 2017 and provided medical follow up for newly pregnant patients, those already pregnant, and patients in the immediate postpartum period. Epidemiological data was collected. Results Of the 50 patients, 8 (16%) with a present or future desire to become pregnant, 24 (48%) pregnant, just only one presented gestational diabetes; and 18 (36%) were in the immediate postpartum period. The median age was 32 years (SD=6.16). The 18 births were live births obtained by caesarean section, 8 (55.8%) were pre-term (<37 WG) and none presented eclampsia or preeclampsia. Of the patients, 22 (44%) had a diagnosis of RA, 10 (20%) had SLE, 10 (20%) had Antiphospholipid Syndrome, and the remaining 8 (16%) had other diagnoses (table 1). Only 18 (36%) had previous abortions.Abstract AB1419HPR – Table 1 Association between current status and diagnosis Current status Systemic Lupus Erythematous Rheumatoid Arthritis Antiphospholipid Syndrome Other Total Reproductive age 0 (0%) 5 (10%) 2 (4%) 1 (2%) 8 (16%) Pregnant 7 (14%) 6 (12%) 6 (12%) 5 (10%) 24 (48%) Postpartum 3 (6%) 11 (22%) 2 (4%) 8 (16%) 18 (36%) Note: n=50 Conclusions The evaluation of patients with RD requires a close follow-up, which is why the population of reproductive age with RD must be seen early on. Considering that our results revealed a high percentage of preterm live births medical attention must be provided from the preconception to the postpartum period. References [1] Ching Soh May, Nelson-Piercy Catherine, High Risk pregnancy and the rheumatologist. Rheumatology. 2015;54(4): 572–587 [2] Alvarez-Nemegyei J. Cervantes-Diaz MT, Avila-zapata F, et al. Desenlace obstétrico antes y después del inicio de la artritis reumatoide. Rev Mex Imss2011;49:599–604 Disclosure of Interest None declared