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The decrease in noradrenaline concentration in the posterior tibial artery with age.

The concentrations of noradrenaline and adrenaline were studied in specimens of the posterior tibial artery obtained from 18 subjects at postmortem examination. The mean noradrenaline concentration was 167 ng/g artery (range 17-449 ng/g) and the mean adrenaline concentration was 5 ng/g (range 0--21 ng/g). There was no difference in noradrenaline and adrenaline concentrations expressed in ng/g between male and female subjects. Expressed in ng/cm artery the arterial noradrenaline concentration was insignificantly lower in the females than in the males. The arterial noradrenaline concentration decreased considerably with age and to the same extent in both sexes.