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Early fresh‐frozen plasma transfusion decreases the risk of retinopathy of prematurity

Insulin‐like growth factor 1 (IGF‐1) and IGF‐binding protein‐3 (IGFBP‐3) play a main role in the pathogenesis of retinopathy of prematurity (ROP). Fresh‐frozen plasma (FFP) from adult donors may be an actual source of IGF‐1 and IGFBP‐3 because it contains higher concentrations. The objective was to evaluate whether FFP transfusions can decrease the occurrence of ROP in a cohort of preterm infants.