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Immunohistological study in chordomas

An immunohistological study of 15 chordomas, six chondrosarcomas, four liposarcomas and seven carcinomas on paraffin embedded samples using anti‐cytokeratin, anti‐epithelial membrane antigen (EMA), anti‐S100 protein, anti‐vimentin and anti‐neurofilaments showed that chordomas has a characteristic immuno‐staining, i.e. positive for cytokeratin, EMA, S100 protein and vimentin; and negative for neurofilaments. This immuno‐staining allows a clear distinction of chordomas from other tumours.