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Contribution of in-vitro fertilization to classical ovulation induction.

Enormous progress has been made in the induction of follicular growth in the context of IVF. This has led to a better understanding of the physiology of follicular maturation and to a better use of HMG and FSH for classical ovulation induction used for infertile couples. Six points are discussed: (i) criteria for monitoring ovulation; (ii) when to start treatment; (iii) significance of a premature LH surge; (iv) the dose of HMG; (v) the dose and results of pure FSH; and (vi) analogues of LHRH. IVF has modified our classical therapeutic habits and has led to an increased efficiency in gonadotrophin treatments of infertility.