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An update on the MNS blood group system

Abstract This update of the MNS blood group system (Reid ME. MNS blood group system: a review. Immunohematology 2009;25:95– 101) reports three new antigens of the MNS system numbered MNS47, MNS48, and MNS49; new glycophorin (GP) variants associated with silent and weak expression of MNS antigens; and the results of new studies on associations of MNS antigens with band 3, Rh proteins, and malaria. The addition of these three antigens brings the total number of antigens in the MNS system (International Society of Blood Transfusion system 2) to 49.