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Dosimetry model for photodynamic therapy with topically administered photosensitizers

Photodynamic therapy (PDT) based on topical application of photosensitizers has been under development over the last years. Typical applications are treatment of basal cell carcinoma of the skin and photoablation of the endometrium. The dosimetry for topically administered photosensitizers must take a time‐dependent inhomogeneous drug distribution into account together with the conventional parameters such as optical scattering, absorption, and photobleaching.