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Extinction of Blood Pressure and Heart Rate Responses to Conditioned Fear

Post‐traumatic stress disorder (PTSD) is characterized by an impaired ability to extinguish fear associations that trigger exaggerated neurophysiological responses, which may contribute to increased cardiovascular (CV) risk in these individuals. The objective of this study was to evaluate the effects of learned inhibition or extinction on the conditioned cardio‐autonomic response during fear memory recall. We hypothesized that extinction training would lead to a temporary reduction of conditioned heart rate (HR) and systolic blood pressure (SBP) responses.