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Plantar polypoid lesion: challenge.

CASE REPORT A 52-year-old Ukrainian woman presented with a bulging lesion on her left foot. She had it for 3 years and it had been treated with cryotherapy a year ago. The lesion had been growing rapidly over the last few weeks, reaching a diameter of 3 · 3 cm and a height of about 2 cm. Clinically, a well-circumscribed, tender, reddish-gray, superficially ulcerated and polypoid mass with a large base was located in the center of the sole of her left foot (Fig. 1). Neither apparent lymphatic involvement nor other cutaneous lesions were revealed. The voluminous lesion was not painful, but the patient limped when walking. The patient underwent surgical excision. The histopathological examination showed relatively uniform spindled cells with little cytoplasm, high mitotic count, and minimal collagen production (Figs. 2, 3). Immunohistochemistry revealed positive vimentin and weakly positive actin (Fig. 4). Desmin, CD99, CD34, B-cell lymphoma 2, human melanoma black-45, S100, epithelial membrane antigen, and pancytokeratines were all negative. Chest x-ray and abdominal computed tomography resulted normal.