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Impact of Dietary Fatty Acids on Chylous Effusion in a Mouse Model of Generalized Lymphatic Anomaly

Generalized lymphatic anomalies (GLA) are complicated vessel malformations that can result in impaired lymphatic function. Potential GLA complications include lipid‐rich lymph in the thoracic cavity or abdomen, respectively chylothorax and chylous ascites. To reduce the potential for chylous accumulation, GLA patients limit dietary fats. We hypothesized that dietary fatty acid composition impacts the potential for lymphatic dysfunction and chylous effusion in GLA.