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Fatigue in Palliative Care Patients

SUMMARY Fatigue is the most common symptom reported by patients approaching death. There is no generally accepted definition of this symptom. Some authors consider asthenia to be the same as fatigue, others do not. This monograph treats them as the same symptom. Fatigue may have multiple causes involving physical, emotional, and psychological factors. Drugs may cause or exacerbate fatigue. Identification and management of underlying causes, supportive therapy and drug therapy are described. Evaluation instruments that have been used to assess fatigue are described. Some open research questions are listed. A treatment algorithm, evidence tables and drug therapy tables are presented.