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[Study on the alkaloids in the stems and leaves of Stephania cepharantha (II)].

OBJECTIVE
To study the alkaloids in the stems and leaves of Stephania cepharantha Hayata.


METHODS
The dried stems and leaves of Stephania cepharantha Hayata were percolated with 95% ethanol and the solvent was removed by rotary evaporation to give a concentrate, and the concentrate was extracted by petroleum ether and chloroform. Column chromatograghy on MCI CHP 20P, silica gel, Rp-18, Sephadex LH-20 and polyamide were applied for the isolation and purification of the chloroform fraction. The structures were elucidated by their physicochemical properties and spectral data.


RESULTS
Five alkaloids were obtained and identified as, Stephasunoline (I) Aknadinine (II), Discretamine (III), Acutumine (IV), Sinomenine (V).


CONCLUSION
Compounds I, III, IV are isolated from this plant for the first time, and compound IV is isolated from the genus for the first time.