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Ultrasonography Preceding Diagnostic Amniocentesis and Its Effect on Amniotic Fluid Cell Growth

Experience with 107 consecutive patients with and without ultrasonography preceding diagnostic amniocentesis is presented. Cell cultures and alpha-fetoprotein levels were obtained on all specimens. Adequate cell growth was found in both groups. The frequency of bloody taps was reduced from 15 to 6.9% and of repeat taps from 6.3 to 0%. Possible complications of amniocentesis which might be avoided by prior ultrasonography are discussed. The use of gray scale or real time ultrasonography prior to diagnostic amniocentesis is stressed.