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Combined IV–intra-arterial thrombolysis: A color-coded duplex pilot study

The authors compared the transcranial color-coded duplex pattern of the middle cerebral arteries (MCAs) before and after IV and combined IV–intra-arterial (IV–IA) thrombolysis in consecutive first-ever stroke patients. Patients receiving combined IV–IA thrombolysis showed greater improvement in flow signal and higher incidence of complete MCA recanalization vs those receiving IV thrombolysis, especially when the MCA was occluded or had only minimal flow.