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Inhibition of mitogen‐induced murine lymphocyte proliferation by Helicobacter pylori cell‐free extract

Background and Aims : Previous studies have shown that lysates of Helicobacter pylori inhibit mitogen‐induced proliferation of human peripheral blood mononuclear cells. The objective of the present study was to determine whether H. pylori cell‐free extract (HPCE) has similar effects on murine lymphoid cells and could, therefore, be used to further delineate the mechanisms of alteration of lymphocyte function by H. pylori.