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DRESS syndrome associated with sulfasalazine therapy

The Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) is a rare life threatening drug hypersensitivity reaction which include a skin rash, fever, lymphadenopathy, hematologic abnormalities and internal organ involvement. Here, we reported DRESS syndrome case in a 55 year old female patient following intake of sulfasalazine for her knee joint pain who was completely recovered with appropriate management.