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A hybrid MRI-based hippocampus segmentation algorithm

In this paper, we propose a new hippocampus segmentation method from MRI by integrating region-growing methods such as K-means clustering with PDE-based level set methods. Starting from a single point provided by the user, our algorithm will first automatically generate an initial seed contour that closely resembles the hippocampus. The seed will then deform based on dynamic level-set equations, and will stop to obtain the final 3D shape when the equilibrium of the PDE is reached. In comparison with other hippocampus algorithms, our method is very efficient; Algorithm