{'fraction_non_alphanumeric': 0.015151515151515152, 'fraction_numerical': 0.008522727272727272, 'mean_word_length': 5.3293413173652695, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Anticholinesterase Activity of Astragalus gombiformis Extracts

Abstract This study aims to evaluate the anticholinesterase activity of different extracts of Astragalus gombiformis Pomel, a wild desert species of Tunisia flora. The anticholinesterase activity of extracts was measured by the colorimetric method of Ellman et al. using human plasma as enzyme source. The effects of the incubation time and the temperature were also studied. Our finding showed that the anticholinesterase activity can be detected after a shorter incubation time than the time generally used for this assay. The temperature of 37°C seems to be more adequate for the evaluation of anticholinesterase activity. For an incubation time of 15 min, the extracts showed different activity levels. Among them, ethyl acetate aerial part extract was found the most active, with an IC50 of 110µg/ml. Considerable anticholinesterase activity of A. gombiformis extracts was shown and this finding suggests that this species can be a possible source of anticholinesterase natural products.