{'fraction_non_alphanumeric': 0.02304964539007092, 'fraction_numerical': 0.0, 'mean_word_length': 5.569767441860465, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Single‐Cell Sequencing in the Genetic Model of Mitochondrial Dysfunction Reveals Heterogeneity of Lung Endothelial Cells and Novel Targets in Pulmonary Hypertension

Pulmonary hypertension (PH) is a complex, lethal vascular disease and currently has very limited treatment options with no cure. Severe pulmonary vascular remodeling and right ventricular (RV) hypertrophy in PH ultimately lead to RV failure. Endothelial dysfunction (ED) is demonstrated to play a key role in the initiation of PH. However, the pathogenic mechanisms leading up to ED remain unclear.