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Effect of hypothyroidism on the biogenic amines of the epididymis of rat.

Concentrations of norepinephrine and dopamine in various parts of the epididymis of rats have been determined. Effects of thyroidectomy and castration (15 days) and administration of thyroxine (2 micrograms/100 g body weight) and testosterone (1 mg/rat/day) were studied. The content of these amines did not change after thyroidectomy, although orchidectomy reduced same. Administration of thyroxine to animals that had thyroid and testes removed enhanced the catecholamine content of the epididymis.