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Interleukin‐4 and ‐13 expression is co‐localized to mast cells within the airway smooth muscle in asthma

Background Airway smooth muscle infiltration by mast cells is a feature of asthma and not eosinophilic bronchitis. In asthma, Th2 cytokines have been implicated as playing a critical role in the development of airway inflammation and hyper‐responsiveness. Whether inflammatory cells within the airway smooth muscle release these cytokines is unknown.