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Alopecia areata: immunofluorescence and other studies

In a study of 24 patifents with alopceia areata, scalp biopsies were examined for immunofluorescence; all were negtive. A number of other tests also failed to confirm an auto‐immune acrtology for this disease. A possible explaation lies in the heterogeneity of alopecia areata, only a small proportion of cases being of the auto‐immune type.