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Histopathological study of typhoid perforation of the small intestines.

A retrospective study was made on 184 cases of typhoid fever with perforation of the small intestines, during the period of 1972--1976. There is a constant increase noted in the morbidity and perforations of the small intestines complicating this disease. 50% of the cases were young adults between the age of 15 to 30 years and the 2 youngest cases were 3 year old children. Contrary to other reports, our studies revealed a significant predominance among male patients (77.2%). The pathological changes were typical and basically similar to that described by other investigators.