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Aplasia cutis congenita of the scalp.

We read with great interest the recent article by Yilmaz et al on an infant with a large full thickness skin and skull defect on the scalp. The infant suffered from other malformations which proved to be fatal. According to Frieden classification the patient was classified in group 4 (3). Aplasia cutis congenita is a rare disorder that is characterized by the absence of skin in a single or multiple areas, more frequently on the scalp. Occasionally the underlying structures, such as the skull and meninges, are affected (2). Genetic factors, teratogens and trauma have been suggested as etiological factors, whereas it has been associated with various syndromes (1).