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[Idiopathic progressive atrophoderma of Pasini-Pierini with the presence of antinuclear antibodies].

Atrophodermia idiopathica progressiva Pasini-Pierini (AIPP) in two young female patients is described. This disease, which begins in the second decade, is slowly progressive and has the characteristics of an originally atrophic dermatosis. No regression to sclerosised lesions could be observed. The distribution of lesions was a strictly one-sided, with the radicular pattern of some lesions suggesting the participation of neurogenic factors. The finding of antinuclear antibodies of the nucleolar type suggests an immunological pathogenesis. HLA typing did not reveal any extraordinary patterns or, interestingly, any of the types associated with immunological diseases.