{'fraction_non_alphanumeric': 0.01417004048582996, 'fraction_numerical': 0.006578947368421052, 'mean_word_length': 5.009118541033435, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Ovarian ablation for breast cancer.

Gastric juice obtained from fasting individuals was treated and analysed. From it a fraction was obtained which had a molecular weight of about 2 x 106. It showed distinct blood group activity consonant with that of the person from whom the sample came, and like the blood group substances obtained from ovarian cysts it was composed of about one-third amino-acids and two-thirds sugar residues. The present view of the structure of this type of molecule is that it has a central protein or peptide core from which numerous polysaccharide chains project. They are linked to the core by glycosidic linkage to the hydroxy groups of serine and threonine.2 3 Gels formed from such molecules show two features which must largely influence their biological effects. Since no two bodies can occupy the same space at the same time, solutions, and of course gels, of these molecules exhibit the phenomenon of excluded volume.4 This means that large molecules are prevented from entering whereas small molecules are unhindered. Secondly, even molecules small enough to enter the interstices of the gel may have their movements hindered by entanglement with the relatively rigid polysaccharide side-chains, and hence a sieving effect is exerted on them as they pass through the gel.5 These properties must influence the interchange of molecules between the mucous membrane and the gastric contents. The movement of hydrochloric acid would be unimpeded but macromolecules in the food would be effectively barred from direct contact with the epithelium. Pepsin, a relatively small protein of molecular weight 36,000, is presumably within the range of substances capable of traversing the mucin gel. It is tempting to assume that the film of mucin exerts a protective action against potential ulcerating agents, but in the present state of ignorance of the pathogenesis of peptic ulceration the mechanism of such protection remains entirely speculative.