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Local application of an antifibrinolytic in tonsillectomy A double-blind study

TONSILLECTOMY is widely used all over the world. The incidence of haemorrhage after this procedure varies a great deal, but in a number of large series it seems to have been between 2 and 3 per cent. Owing to the very large number of tonsillectomies, even a minor reduction of this incidence would be a great gain. Overbosch and Hart (1970) have reported a significant reduction in the incidence of haemorrhage by the local application of epsilon-aminocaproic acid (EACA). The present study was designed to test this finding and to ascertain whether signs of systemic fibrinolysis exist in cases where tonsillectomy is followed by haemorrhage.