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Chromosomes abnormalities caused byTegretol drug on the albino rat

The present work was performed to illustrate the harmful effects of different doses of Tegretol which has active ingredient (Carbamazepine; CBZ) on the genetic of the adult albino rat and on the prenatal foetuses of rat at 20 th day of gestation. Tegretol (CBZ) noticeably, increased chromosomal aberrations and decreased the mitotic index.