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Pimavanserin in depression treatment improves sexual functioning

may be hindered, however, by potential confounding by indication, given that the affective disorders that often trigger benzodiazepine use are also associated with dementia risk. Recognizing this limitation, Merete Osler, M.D., professor at the Center for Clinical Research and Prevention at Bispebjerg and Frederiksberg Hospitals in Denmark, and a colleague sought to minimize risk of confounding by indication in this new study examining whether treatment with benzodiazepines and Z-drugs increases risk of subsequent dementia. They also examined risk based on drug type and the timing and duration of treatment.