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Re: A Review of the Principles of Texture Analysis and Its Role in Imaging of Genitourinary Neoplasms.

available at http://www.ncbi.nlm.nih.gov/pubmed/30448920 Editorial Comment: This article initially explains the principles of texture analysis, which involves quantification of homogeneity or heterogeneity of a particular tissue using statistical analysis of the grayscale values. This is initially performed on a pixel-by-pixel basis looking at a histogram curve and the variety or heterogeneity within that pixel. The pixel may also be assessed in comparison to adjacent neighboring pixels. Textural analysis is being used to assist in characterizing renal masses (specifically fat poor angiomyolipoma from renal cell carcinoma), characterizing renal cell carcinoma subtypes, and assessing the aggressiveness of a renal tumor and predicting the metastatic potential. Textural analysis studies are promising in prostate cancer as well, where lower kurtosis on apparent diffusion coefficient imaging and lower entropy on T1 post-contrast imaging are predictive of tumor. Renal cell carcinoma, prostate cancer, bladder cancer and adrenal neoplasms are all discussed. Cary Siegel, MD 444 IMAGING Copyright © 2020 American Urological Association Education and Research, Inc. Unauthorized reproduction of this article is prohibited.