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In vitro glucose concentration estimation by means of fractional order impedance models

This paper presents the application of fractional calculus tools, i.e. fractional order impedance and Cole-Cole elements to detect, measure and estimate glucose concentrations by means of electrochemical impedance spectroscopy. In this paper, the fractional order impedance model is presented and compared with the measured impedance. The model parameters are related to various physical conditions of the test-cells and a baseline measurements along with blind evaluation are presented. The results obtained indicate that the fractional order impedance model can capture the dynamics of the measured impedance.