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What Governs the Unzipping Process of Double-Stranded DNA

The unzipping process of double-stranded DNA is analysed using a discrete model at the base level [Chin. Phys. Lett. 22 (2005) 1540]. The numerical results are consistent with the experimental observations on the force-displacement behaviour including the sequence-dependence. We find that the hydrogen bond interaction in a base pair is crucially important to the force–displacement profile.