{'fraction_non_alphanumeric': 0.025547445255474453, 'fraction_numerical': 0.008211678832116789, 'mean_word_length': 5.568862275449102, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Appropriate Polypharmacy in Older People in Primary Care

Introduction • The prescribing of multiple medicines, or polypharmacy (≥4 regular medicines), is increasingly common in clinical practice, particularly in older people (age ≥65 years)1 • Polypharmacy in older people is linked to hospital admissions, adverse drug events and mortality2, however, evidence suggests that polypharmacy may be entirely appropriate and necessary, particularly when prescribing for older people who have more than one medical condition3 • Intervention studies have aimed to address the use of polypharmacy in older people, yet randomised controlled trials (RCTs) often differ in the outcomes reported, which has resulted in an inability to synthesise results4 • The COMET (Core Outcome Measures in Effectiveness Trials) initiative has suggested that one method of addressing this problem is through the development of a core outcome set (COS)5 • A COS is an agreed and standardised set of outcomes or outcome domains which should be measured and reported, as a minimum, in all trials in a specific clinical area5