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Monitoring Tumor Response to Therapy with 18F-FLT PET

Monitoring Tumor Response to Therapy with 18F-FLT PET Imaging tumor cell proliferation is of high interest for both research and clinical practice in oncology. High proliferation rates are characteristic of most malignant tumors, whereas in benign tumors the fraction of proliferating cells is comparatively small. Therefore, imaging of proliferation may provide a sensitive and specific tool for differentiation of benign and malignant tumors. Furthermore, proliferation imaging may be used for detection of metastatic disease in patients with known cancer. Because many benign lesions that mimic metastases