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Management of squamous cell carcinoma of the oropharynx

Squamous cell carcinoma is the most common malignant tumor of the oropharyngeal region of the head and neck, although it is infrequently encountered in the Western world. Early tumors are uncommon and are effectively treated either by primary surgery or external beam radiotherapy. Advanced disease, the most frequent stage of disease at presentation (75%), requires thoughtful, structured, and well-planned treatment strategies if patients are to experience relief of symptoms, preservation of quality of life, and realistic expectation for cure. Primary tumor and cervical nodal disease may require differing management strategies to control disease and may include the following treatment modalities: chemotherapy, radiotherapy external beam fractions, multiple fractionated radiotherapy, brachytherapy, and surgery to the primary and/or neck disease. However, new novel modes of treatment, as reported, may not be available universally to treat all patients.