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Modulation of allergic responses by mitochondrial STAT3 inhibitors

Recently, we have shown that mast cell mitochondrial STAT3 could serve as a new target for the regulation of the allergic response as it plays an essential role in immunologically mediated degranulation of mast cells. In the present work, we explored how two recently developed mitochondrial STAT3 inhibitors (Mitocur‐1 and Mitocur‐3) modulate the allergic response.