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Novel KEL*02M allele in Austria encoding a Kmod phenotype

The KEL glycoprotein is encoded by the highly polymorphic KEL gene comprising 19 exons. Diverse molecular events were described so far with a silencing or weakening effect on KEL1 or KEL2. To date, a total of 20 gene alterations were associated with a KEL:02M phenotype. Upon routine blood group typing, a sample from a female Caucasian blood donor drew attention due to strongly diminished reactions with human anti-KEL2.