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[Human papillomavirus (HPV) and DNA test in inverted papillomas of the nasal cavities and paranasal sinuses].

To understand the relationship between inverted papillomas and human papilloma virus, 38 cases (44 specimens) of inverted papillomas of nasal cavities and paranasal sinuses were examined for the presence of human papilloma virus (HPV) DNA using polymerase chain reaction (PCR). The genetic studies were performed on the formalin fixed and parafin embeded specimens. The results showed that 30 cases were infected by HPV-DNA, in which HPV11 positive was noted for 30 times (68.2%), HPV16 positive for 18 times (40.9%), and HPV18 positive for 2 time (4.5%). 18 HPV11,16 (40.9%) and 2 were HPV11,18 (4.5%). The result suggests that HPV plays a role in the etiology of nasal and paranasal inverted papillomas.