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[Peculiarities of present-day morbidity of influenza A (H1N1 swl)].

A rise in influenza morbidity became a topical problem again after the identification of a new H1N1 swl strain in California in 2009. In June 2009, WHO announced the onset of a new pandemic. We consider the epidemiological situation as regards respiratory viral diseases during recent years with special reference to influenza A (H1N1 swl). The literature data demonstrate the multifaceted clinical picture of this disease attributable to genetic variability of the virus and the immune response to infection. Most cases of influenza A (H1N1 swl) are either mild or severe diseases; it may be especially serious in previously unaffected young and middle-aged subjects and develop into acute respiratory distress syndrome with the fatal outcome. As a rule, the most severe cases are recorded in high-risk groups. Pathomorphological changes associated with pandemic influenza are described in comparison with those documented in earlier pandemics.