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Assignment1 of the human solute carrier family 4, sodium bicarbonate cotransporter-like, member 10 gene (SLC4A10) to 2q23→q24 by in situ hybridization and radiation hybrid mapping

Intracellular pH (pHi) regulators that maintain the acidbase balance play an important role in a wide range of biological responses to stimuli in many cellular functions (Busa, 1986). A family of bicarbonate transporters is one of the important pHi regulators under physiological conditions. Recently, we isolated a novel cDNA encoding a bicarbonate transporter-like protein (solute carrier family 4, sodium bicarbonate cotransporter-like, member 10; name and symbol approved by the HUGO Nomenclature Committee) from the mouse insulin secreting cell line MIN6 cDNA library (Wang et al., manuscript in preparation). We have cloned a part of the human homologue of the gene, SLC4A10 and mapped it to human chromosome 2q23→q24.