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New directions in anticoagulant and antiplatelet treatment.

The advent of two new classes of drugs, the thrombin inhibitors and the IIB/IIIa platelet receptor blockers, may lead to major changes in anticoagulation practice the coming decade. We review the currently available data from clinical studies and speculate on how these classes of drugs may come to be used in clinical practice, bearing in mind that the benefits of these classes of drugs have not yet been determined precisely.