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Leukoence­phalomalacia in a two-year-old Thoroughbred colt

Leukoencephalomalacia is a disease of horses and donkeys caused by the ingestion of the mycotoxin fumonisin produced by the fungus F. proliferatum. In June 2015, a 2-year-old Thoroughbred colt kept in a feedlot around Tehran, Iran was presented with severe neurologic signs for clinical examination. Based on clinical evidences, history of ingestion of inappropriately stored commercially prepared feedlot concentrates and post mortem examinations, equine leukoencephalomalacia was suspected. Histopathologic findings, the results of feed fungal culture and mycotoxin analysis confirmed the disease.