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Investigation of relationship between coronary angiography results and neutrophil/lymphocyte ratios of patients with acute coronary syndrome in the emergency department

Purpose: We aimed to identify patients diagnosed with acute coronary syndrome (ACS) in the emergency department and for whom medical treatment was decided during coronary angiography, according to their neutrophil/lymphocyte ratios at the time of admission.

Material and Method: Patients diagnosed with ACS in the emergency department and undergoing coronary angiography (CAG) were included. The patients were divided into two groups as non-ST-segment elevation acute coronary syndrome and ST-segment elevation myocardial infarction. According to their CAG results, the patients in both groups were classified as those who underwent coronary intervention and those who did not. In addition, demographic data such as age and gender, neutrophil/lymphocyte ratio, monocytes, aspartate aminotransferase, and C-reactive protein values of these patients were recorded in the data form. These values were statistically compared between those who decided on a coronary intervention during CAG and those who did not.

Results: A total of 647 patients were included in the study. The patients were divided into 325 patients with non-ST-segment elevation acute coronary syndrome and 322 with ST-segment elevation myocardial infarction. The age range of the patients in both groups was 30 to 93. Monocyte, aspartate aminotransferase, neutrophil/lymphocyte ratio, and gender were significant in the diagnosis process. The diagnosis was the only effective factor in detecting patients for whom a coronary intervention was decided during CAG. Gender, age, neutrophil/lymphocyte ratio, aspartate aminotransferase, C-reactive protein, and monocyte values were insignificant.

Conclusion: Even if some parameters such as monocyte count, N/L ratio, and aspartate aminotransferase in patients diagnosed with ACS in the emergency department are ineffective in predicting the medical treatment decision during CAG, they may help in the clinical decision-making process.