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[Effect of reduced concentration of various electrolytes on the myocardium during reperfusion].

Reperfusion of isolated rat heart after cardioplegia with a solution containing 20% less Na+, K+, Ca2+, Mg2+, and H+ (the blood plasma electrolyte concentration of patients changes just within these ranges during operations on the open heart) leads to severe cardiac insufficiency. The direct cause of the disturbed contractile function of the heart in this case is reduced osmolality of the perfusion solution and/or simultaneous decrease of Na+ and H+ concentration.