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Chapter 10: Pertussis

Pertussis, or whooping cough, is caused by the bacterium Bordetella pertussis. It is characterized by paroxysmal coughing followed by a characteristic inspiratory whoop. Secondary bacterial pneumonia is the cause of most pertussis-related deaths. Other complications, though infrequent, can include neurological complications such as seizures and encephalopathy, otitis media, and conditions resulting from the pressure effects of severe paroxysmal coughing including pneumothorax, epistaxis, subdural hematomas, hernias, and rectal prolapse. Disease rates and risk of serious complications, including death, are highest among young children, particularly those <1 year of age; disease in adolescents and adults tends to be milder.