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[PP.18.03] THE IMPACT OF ARTERIAL HYPERTENSION ON MORTALITY IN PATIENTS WITH MYOCARDIAL INFARCTION WITH ST SEGMENT ELEVATION

Objective: Arterial hypertension (AH) is one of the main reason for the appearance of cardiovascular events. According to the available data, it is not clear whether the patients with arterial hypertension have worse outcome after myocardial infarction. The aim of our study was to determine the incidence of arterial hypertension in patients with myocardial infarction with ST segment elevation, and the impact of arterial hypertension on mortality in these patients Design and method: This study included 507 consecutive STEMI patients treated with primary percutaneous coronary intervention in Clinical Centre of Serbia and for whom the data were collected after 36 months. AH was diagnosed according to the European guidelines for diagnosing and management of hypertension. Results: AH was present in 337 (66,47%) patients. The patients with AH were older (58,1 ± 10,45) than the patients without AH (54,52 ± 11,36), and in the group with AH there were more female patients (24,92%:17,20%). Out of the total number of patients with AH, 231 of them (68,55 %) had a regulated blood pressure during the follow up whereas the unregulated blood pressure was recorded in 106 (31,45%) patients. During a three-year follow up, a cardiovascular mortality (CM) was recorded in 64 patients. Out of the total number of death cases, 29 (12,55%) of them had regulated blood pressure whereas 21 (19,81 %) of them had unregulated blood pressure. The number of deceased patients without AH was 14 (8,24 %). A significant difference in CM (p = 0,026) was recorded between these two groups. The presence of arterial hypertension turned out to be a significant risk factor for CM (p = 0,035; OR 1,969). The patients with regulated blood pressure were at a lower risk for the appearance of CM (p = 0,15 OR 1,376) whereas the patients with unregulated blood pressure were at an increased risk for CM (p = 0.002; OR 2,612). Conclusions: Our study showed that patients with arterial hypertension were at an increased risk for cardiovascular mortality unless they reached the target values of blood pressure.