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Cost‐effectiveness of screening the US blood supply for Trypanosoma cruzi

BACKGROUND: Trypanosoma cruzi, the etiologic agent of Chagas disease, is a potential threat to transfusion recipients in the United States. The cost‐effectiveness of seven testing strategies was evaluated against no testing and hierarchically in incremental analysis. Donor‐specific strategies included testing donors born in endemic countries, testing all donors a specific number of times, or testing all donors every time. Component‐specific strategies are based on screening platelet‐containing donations.