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[Study on the release of oleanolic acid loaded nanocapsules in vitro].

OBJECTIVE
To study the release of oleanolic acid loaded nanocapsules in vitro.


METHODS
The rules of drug release in vitro from oleanolic acid loaded nanocapsules were observed by dynamic penetration system and HPLC.


RESULTS
The profile curve of oleanolic acid loaded nanocapsules was fit for the Weibull equation. The release t(1/2) of oleanolic acid loaded nanocapsules was about 6.7 times as that of original oleanolic acid.


CONCLUSION
Oleanolic acid loaded nanocapsules have obviously sustained effect.