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Dynamic and phagocytotic activity of human granulosa cells in vitro.

This study has examined the interaction of human granulosa cells in culture with inert latex particles to determine whether an active role in phagocytosis may be contemplated. The report shows that granulosa cells exhibit various types of movement in culture. They also interact with inert latex particles which are actively phagocytosed. Uptake of an individual bead took approximately 30 min and was affected by agents modulating levels of divalent cations. The physiological relevance of this property of granulosa cells is not known.