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Fat graft and platelet-rich plasma treatment for localized facial scleroderma

Scleroderma is an autoimmune disorder characterized by hardening of the skin on the hands, arms, and face. Immunosuppressors, vasodilators, and physiotherapy are among the treatments for scleroderma. Although these treatments can improve quality of life, the treatment response in locally affected areas may be poor. At present, there is no specific treatment for localized fibrotic skin lesions in scleroderma, although stem cell treatment shows promise for local symptoms. We describe the case of a patient with facial skin symptoms of scleroderma treated with platelet-rich plasma combined with fat grafts rich in stem cells.