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The vertically polarized magnetic field has no effect on the content of pteridine in mouse liver

We investigate the content of pteridine levels in mouse liver under exposure to a 50 Hz linearly (vertically) polarized magnetic field. Tetrahydrobiopterin (BR/sub 4/), neopterin (NP), biopterin (BP) and GTP-CHI activity were measured. Five week-old mice were exposed continuously to 50 Hz, 0.35 mT (RMS) for periods of 1, 3 and 6 weeks. The level of BH/sub 4/ in the exposed group was no different from that of the sham-exposed group. The levels of NP in both groups became almost the same. Due to no changes in NP and BH/sub 4/ level, it is suggested that the vertically polarized magnetic field does not affect the immune system and biosynthetic pathway from q-BH/sub 2/ to BH/sub 4/ in mice. There were no changes in the level of BP between the two groups. From these results, the vertically polarized magnetic field does not affect the pteridine level in mice.