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The effect of urinary tract infection on patient and graft survival rate in a group of kidney transplanted patients

Introduction: Urinary tract infection (UTI) is one of the most common infection following kidney transplant surgery. Objectives: This study was aimed to evaluate the effect of UTI after transplant on patients and graft survival rate. Patients and Methods: This study was cross-sectional and the data collected retrospectively. Kaplan-Meier method was used to calculate the survival rate of patients and log-rank test was applied to compare the survival curves. Cox regression model was applied for modeling the factors affecting survival rate. The data were analyzed using SPSS version 19. The level of significance considered less than 0.05. Results: The mean duration of follow-up in infected and non-infected patients following kidney transplantation surgery were 53.78±24.5 months and 67±40.8 months, respectively. Ten-year survival rate in infected by UTI and in non-infected by UTI were 78±0.03% and 89±0.02%, respectively. Also, 10-year graft survival rate in infected patients and in noninfected patients were 71±0.03% and 88±0.02%, respectively. Log-rank test showed a significant difference between infected and non-infected patients regarding graft survival rate (P<0.001). Conclusion: The results showed that the survival rate of patients was different in infected and non-infected patients. This finding indicated the importance of follow-up in patients with infection following kidney transplant surgery.