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The Role of Three-dimensional Scaffolds in the Regeneration of Joint Cartilage

A variety of polymer scaffolds with pore architecture consisting of interconnected spherical pores with the same architecture but varying mechanical properties (in particular elastic modulus), water sorption capacity, pore surface characteristics (surface tension, presence of hydrophilic groups or electric charges) was prepared and implanted in a 3mm diameter full thickness defects in the knee joint cartilage of rabbits in order to show the influence of the scaffold properties on the histological characteristics of the regenerated