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Cancer clinical trials.

• Clinical trials are research studies that involve people and test new ways to prevent, detect, diagnose, or treat cancer and other diseases (see Question 1). • Every clinical trial has a protocol that describes what will be done in the trial, how the trial will be conducted, and why each part of the trial is necessary (see Question 6). • National and international regulations and policies have been developed to protect the rights, safety, and well-being of people who take part in clinical trials and to ensure that trials are conducted according to strict scientific and ethical principles (see Question 7). • Informed consent is a process through which people learn the important facts about a clinical trial to help them decide whether or not to take part in it, or whether to continue participating in it (see Question 8). • Many states require that insurance companies cover the costs of routine care for people taking part in a clinical trial. In other states, voluntary agreements between the states and insurance companies include such a provision. However, coverage varies by state, by health insurance plan, and by type of clinical trial (see Question 14).