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Orthophosphate treatment of calcium lithiasis associated with idiopathic hypercalciuria.

Oral orthophosphate treatment was given to 33 subjects with idiopathic hypercalciuria, 28 of them with calcium salt lithiasis. A decrease in urinary calcium excretion was observed in 31 of the subjects. The treatment appeared clinically beneficial in 8 out of 11 patients with metabolically active stone disease. Indications and contraindications to oral orthophosphate treatment are discussed.