{'fraction_non_alphanumeric': 0.028437255413514217, 'fraction_numerical': 0.012001043569006, 'mean_word_length': 5.239826370048833, 'pattern_counts': {'":': 0, '<': 1, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Mixed reality-based online interprofessional education: a case study in South Korea

Purpose The purpose of this study was to explore undergraduate medical and nursing students’ satisfaction with their mixed reality (MR)-based online interprofessional learning experience in South Korea. Methods This study used a case study design. A convenience sample of 30 participants (i.e., 15 third-year medical students and 15 fourth-year nursing students) participated in a 120-minute MR-based online interprofessional education (IPE) that consisted of visualization of holographic standardized patient with ischemic stroke, online interprofessional activity, and debriefing and reflection sessions. Following the MR-based online IPE, data were collected through Modified Satisfaction with Simulation Experience Scale survey and were analyzed using descriptive analyses and independent t-tests. Results Although medical and nursing students were highly satisfied with MR-based online interprofessional learning experience, nursing students were significantly more satisfied with it compared with medical students. Conclusion These results suggest that the integration of MR and online approach through the structured clinical reasoning process in undergraduate health professions programs can be used as an educational strategy to improve clinical reasoning and critical thinking and to promote interprofessional understanding.


Introduction
There is an increasing awareness of the importance of interprofessional education (IPE) in undergraduate health professions programs. IPE is defined as teaching and learning the process where two or more health professions students learn with, from, and about one another to promote effective collaboration for delivery of safe and quality patient care [1,2]. However, education for undergraduate health professions students remains siloed as the training takes place mainly in their specific professional fields [3]. This can cause difficulties in working within a healthcare team after graduation if newly graduated healthcare professionals have no previous experience of interprofessional collaboration [3].
As an educational tool, mixed reality (MR) is one of the most emerging immersive technologies in undergraduate health professions education programs [4,5]. It is a type of augmented reality that allows digitally produced objects to be overlaid on a real environment, using a headset [4]. As MR technologies, Microsoft HoloLens and HoloPatient application (Microsoft Corp., Redmond, USA) are recently used in nursing education in Western countries such as Australia and New Zealand [4][5][6][7]. The HoloPatient is a form of holographic standardized patients (HSPs) produced commercially by GiGXR. The use of MR enhances student motivation and engages in active learning [5,7]. It also assists students to develop clinical reasoning, judgement, and assessment skills, allowing them to collect visual and aural cues through improved visualization and reflective practice [5][6][7] [8,9]. Health professions students perceived that online IPE was as effective as in-person session [8]. Health professions students also reported that online IPE provided opportunities to engage in collaborative problem-solving in a team and the importance of including their own professional perspectives [10]. Due to our personal experiences facing difficulties (e.g., geographical barriers if health professions students are from different school regarding the implementation of face-to-face IPE), we sought to develop and implement MR-based online IPE in which medical and nursing students could engage and develop interprofessional understandings.

Design
This study used a case study design through analysis of the survey. A convenience sample of 30 medical and nursing students was recruited through flyers on the bulletin board at one college of nursing and one school of medicine, respectively and voluntarily participated in this study. One mixed group consisted of three medical students and three nursing students, which resulted in a total of five groups.

MR-based online interprofessional education
We divided the MR-based online IPE into three parts, using the clinical reasoning cycle [11] as a structure.
Each part was timed and represented 120 minutes of activity. We used the HSP, namely HoloPatient who portrayed the symptoms of ischemic stroke. In South Korea, stroke is an emergency disease in which the time from onset to treatment is important as the third leading cause of death [12].
For part 1, medical and nursing students met the HoloPatient at their own institution, respectively due to time and resource constraints. A facilitator saw the HSP representing the changes in the level of consciousness, decreased functions of the right side (i.e., facial droop and arm drift) and slurred speech clearly and displayed vital signs in emergency department, wearing the HoloLens, which was projected onto the screen. So, medical and nursing students could see a live streamed HSP in the same environment at the same time. They were asked to spend 10 minutes immersed in HSP of the screen, using from the first step to the third step of the structured clinical reasoning cycle [11].
In part 2 of the 100-minute online IPE, the activity was to emphasize interactive learning and active participation [13]. The interactive approach was facilitated using group discussion, selected presentations, and non-judgmental feedback from two co-facilitators (i.e., one medical faculty and one nursing faculty). In the first step, medical and nursing students in groups had ten minutes to share part 1 activity using from the first step to the third step of the structured clinical reasoning cycle. Then, selected groups presented about what they discussed from the first step to the third step in order during the 10 minutes. They in groups discussed the care plan, using the four steps to the seven steps of the structured clinical reasoning cycle. Mini-lectures were interspersed with group sessions and were used to summarize ideas, show the relationship between theory and practice and re-emphasize the main point.
In part 3, medical and nursing students debriefed their experiences with two co-facilitators. This allowed them to reflect on their learning and how to take that forward.
It helped them to examine their values and beliefs and influence their attitude toward interprofessional collaborative practice.  (Table 1). We calculated the total scores, yielding an index with a minimum score of 33 and a maximum score of 165.

Outcome measures
The Cronbach's alpha of the original SSES in a previous study was 0.77 [14]. Internal consistency of each subscale was reported high: 0.94, 0.86, and 0.85, respectively [14]. In this study, the Cronbach's α of each subscale was high: 0.88, 0.85, 0.95, and 0.94, respectively. We made minor wording changes to 10 to 24 in order to fit MR and stroke contents. The English version of the modified SSES was translated into Korean by the second author [15]. Back translation was conducted by one bilingual South Korean nursing and medical professors.

Data collection procedure
This study was conducted in May 2021. All participants were asked to complete the survey after the MR-based online IPE.

Data analysis
This study used the IBM SPSS ver. 21.0 (IBM Corp., Armonk, USA) for survey. We undertook descriptive analyses to summarize participants' characteristics. We also used independent t-tests to compare the means of the survey of the two samples. All p-values <0.05 were used to identify statistical significance.

Ethical considerations
This study obtained the Ethical approval from the Institutional Review Board of Jeju National University (IRB no., 2021-04-001). We received all participants' informed written consent before the start of this study.

Results
Fifteen 3rd-year medical students and fifteen 4thyear nursing students participated in the MR-based online IPE. The medical students consisted of six female (40%) and nine male (60%) students. Nursing students consisted of 11 female (73.3%) and four male (26.7%).
Nursing students were significantly more satisfied with MR-based online interprofessional learning experiences (p=0.030) ( Table 2).

Discussion
To our knowledge, this was the first study to use MR technology for IPE among undergraduate medical and nursing students in South Korea. MR in undergraduate health professions programs is novel and innovative that needs to be taken into consideration. This study showed that although medical and nursing students were highly satisfied with MR-based online interprofessional learning experience, nursing students were significantly more satisfied with it compared with medical students.
Recently, an Australian pilot study reported that thirteen health professions students (i.e., medicine, nursing, occupational therapy, and dietetics) consistently recognized pain as a patient need [4]. This finding supports the recent pilot study [8]. This is because the use of MR in this study allowed medical and nursing students to view the same HSP displaying the symptoms of ischemic stroke that could appear realistic although this took place at their own institutions respectively. Thus, this finding suggests that the use of MR in IPE can be effective with other health professions students, even full healthcare teams despite being in geographically different areas.
This study showed that medical and nursing students were highly satisfied with MR-based online IPE regarding debriefing and reflection. It seems that two co-facilitation through interactive approach in online IPE was effective. This finding supports the recent study that highlighted the importance of facilitators when using technology to facilitate IPE [10]. Thus, regardless of the form of health professions students' discussions in IPE, it is crucial for facilitators to monitor health professions students' interactions and intervene when necessary to correct any misunderstanding, engage them in deeper learning, and summarize key points.
In this study, nursing students were significantly more satisfied with MR-based IPE experience than medical students regarding clinical learning. The recent COVID-19 situation shortens and limits clinical learning experiences for health professions students, particularly nursing students in South Korea. The use of MR in IPE can give an opportunity for health professions students not only to meet a HSP like a real patient but also to think like a healthcare professional such as doctors and nurses. Also, it can offer health professions students opportunities to develop skills in observing and noticing physical cues, which can improve their adaptation to changes in pateints health and how to interact with other health professionals in health care team.
This study has some limitations. First, the findings in this study may not generalize in South Korea, because one medicine and one nursing institutions were studied.
Second, the survey was completed immediately following the MR-based online IPE. Posttest results of the survey may be different if participants were provided a longer waiting period.
In conclusion, this study suggests that the integration of MR and online approach through the structured clinical reasoning process in undergraduate health professions programs can be used as an educational strategy to improve clinical reasoning and critical thinking and to promote interprofessional understanding.