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[Phenylalanine level in the serum of heterozygotes for phenylketonuria under intensified protein catabolism].

In 10 adult heterozygotes for phenylketonuria varying increase of phenylalanine level in blood during severe virus infection was shown. In three of them hyperphenylalaninemia was developed with the level exceeding the initial one nearly 6 fold. Phenylalanine blood level during infection outgrew the pathogenic threshold. Such type of hyperphenylalaninemia may lead to brain damage both in fetus of women heterozygous for phenylketonuria gene and in heterozygote infants during the early postnatal period.