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Primary Tumors of the Nervous System

This chapter will review the current knowledge about the molecular genetic alterations associated with the initiation and progression of the most common forms of primary nervous system tumors. These include glial tumors, primitive neuroectodermal tumors (PNETs), meningiomas, and schwannomas. We will briefly review recent epidemiological data and the present histopathological classification of primary nervous system tumors. In addition, we discuss the hereditary syndromes predisposing to the development of tumors of the nervous system.