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Improvement of exercise metabolism and carotenoids antioxidant scores with CordyMax and LifePak in young Chinese elite athletes

Cordyceps sinensis and its fermentation product, CordyMax (CM), are used for anti‐aging and health preservation. We have reported CM's anti‐fatigue and endurance enhancement functions in multi‐sport endurance Caucasians athletes (Chin J Clin Pharmacy 2007, 5:16). LifePak (LP) is enriched in carotenoids and antioxidant nutrients to improve antioxidant capability in young athletes (FASEB J 2009, 23:1007.3). We further tested the improvement of exercise metabolism and antioxidant capacity with CM and LP in a self‐controlled trial in young Chinese elite athletes (n=25, 18.1 yrs on average) recruited from China bicycle teams. They received CM 3.18 g/day and LP 2 sachets/day for 6 wks. All subjects remained on the same diet plan and training intensity during the study. Before and after the treatment, subjects performed graded exercise test on cycle ergometer and photonic assays for antioxidant scores. At a work load of 100W, 150W or 200W, RER were reduced significantly by 27%, 31%, & 36% (p<0.001), and blood lactate by 14%, 31% & 33%, and also reduced by 24% & 20% immediately and 3 min after exercise (p<0.05). VO2 peak, HR and O2 pulse were not changed in these elite athletes. Carotenoids antioxidant scores were increased by 21% (p=0.02). In conclusion, our data suggest benefits of CM‐LP in improving antioxidant capacity and exercise metabolisms to enhance endurance capability and reducing risks of exercise injury in Chinese elite athletes.