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Sclerosing mediastinitis and terminal valvular endocarditis caused by fungus suggestive of Aspergillus species.

The case of a 60-year-old woman with the unique combination of fungal sclerosing mediastinitis of at least 12 years’ duration with late onset of aortic valvular endocarditis caused by similar hyphae suggestive of Aspergillus is presented. The patient was maintained in good health by repeated bronchoscopies to relieve bronchial mucoid impactions until her rapid demise after the onset of aortic valvular insufficiency. A brief discussion concerning the relationship of this case to other reported cases is presented.