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STUDIES ON THE MORPHOLOGICAL CHANGES OF ARTERY CAUSED BY EXUDATION – INITIAL CHANGES OF ARTERITIS

The morphological changes of the mesenterial arteries of guinea pig were studied with the administration of intravascular or intraperitoneal injection of soluble immune complexes. The main change consisted of vacuolar alteration of arterial endothelium. This was considered to have been caused by a regurgitation mechanism of the exudated plasma across the arterial wall and is the initial morphologic change of so‐called allergic vasculitis. ACTA PATH. JAP. 22:441–455, 1972.