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Coronavirus disease 2019 and mNGS technology

Coronavirus Disease 2019(COVID-19) is a novel pneumonia caused by Severe Acute Respiratory Syndrome Coronavirus 2(SARS-CoV-2). By May 21, 2020, more than 4.96 million people have been infected, resulting in over 300,000 death in the whole world. Metagenomic next-generation sequencing(mNGS) is a technology that plays an important role in the discovery and detection of COVID-19. This article introduces the role and the technical characteristics of mNGS, and makes a technical summary for the use of this technology in the follow-up fight against the global pandemic.