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(18)-F-fluorodeoxyglucose positron emission tomography/computed tomography study in acute lung injury/acute respiratory distress syndrome.

In accordance with other investigators (2, 3), the authors have reported an increase in (18)-F-fluorodeoxyglucose (FDG) uptake in the lung parenchyma of a small and heterogeneous group of ALI/ARDS patients using positron emission tomography/computed tomography scan in different phases of the disease. Additionally, the authors found heterogeneity in FDG uptake when regional metabolic activity was correlated with lung aeration compartments (hyperinflated, normally aerated, poorly aerated, and non-aerated regions) based on computed tomography density.