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Relationship of serum interleukin‐7 concentration and the coagulation state in children with nephrotic syndrome

Background : Enhanced platelet reactivity may play a significant role in the hypercoagulable state of nephrotic syndrome (NS). Thrombocytosis with platelet aggregation cause the release of some cytokines, among them interleukin‐7 (IL‐7). The aim of the study was to evaluate serum IL‐7 levels in children with the symptoms of NS and to determine a correlation between its concentration and platelet count, other hemostatic factors, and NS intensity.