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[Clinico-immunological characteristics of patients with rheumatoid arthritis and symptoms of cutaneous vasculitis (cooperative Soviet-Polish study)].

The paper presents the results of a comparative study performed in the USSR and Poland of rheumatoid arthritis (RA) patients with extra-articular manifestations of the disease (with skin vasculitis and free of it). The comparison included clinical, biochemical and immunological parameters. The results confirm the role of immune complexes in the onset of vascular affections in RA. High incidence of sensitive polyneuropathy in patients with skin vasculitis allows one to define it as a sign of systemic vasculitis. Rheumatoid nodes occur with similar frequency in both groups. It is shown that the problem of vascular pathology in RA remains complex and that further studies are needed to specify mechanisms of vasculopathy development in RA.