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Mucormycosis or Black Fungus: An Emerging Threat among Covid-19 Patients in India

Abstract: Following the first wave of Covid-19, the second wave wreaks havoc on Indians, infecting them with a mysterious fungal condition known as Mucormycosis (Black fungus). The researchers discovered that using immunosuppressive drugs to treat Covid-19 increased the likelihood of contracting mucormycosis. Mucormycosis molds are more likely to affect patients with (have or who went through) hyperglycemia, ketoacidosis, solid organ or bone marrow transplantation, liver cirrhosis, and neutropenia. To eradicate Mucormycosis, four primary variables must be addressed: early diagnosis, removal of predisposing factors, timely antifungal therapy, surgical removal of all infected tissues, and adjuvant therapies. The management of the diseases is dependent on accurate diagnosis and prompt treatment, which may include antifungal agents as well as surgical intervention with the involved tissues. Many new agents with antimicrobial activity against Mucorales are being studied in addition to the traditional and well-proven first-line therapy of amphotericin B-based drugs or posaconazole. Keywords: Black Fungus, Mucormycosis, Amphotericin B, Posaconazole