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[The history of portal hypertension].

When studying the history of portal hypertension (PH)l one is impressed, as in all branches of medical history, by the inquisitive spirit and the intuition of early investigators who, with simple technical means, acquired a surprising degree of knowledge and understanding. Thus, as early as 1543, Vesalius2 drew an anatomical picture of the portal venous system (Figure 1) to which not much has been added. In the 1650s, only 25 years after Harvey's discovery of the blood circulation, Glisson3 at a dissection in London, established the portal vein as the vessel by which blood was collected from the gastrointestinal tract and returned to the systemic circulation. His tool was a goose quill which he inserted into the portal vein and through which, using a pig's bladder, he injected milk