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Effects of a Single and Course Application of Remote Ischemic Preconditioning on the Physical Performance of Laboratory Animals

Previous publications reported the use of remote ischemic preconditioning (rIPC) as a non-drug method for increasing physical performance. However, the reported data are of a contradictory nature. Aim: to evaluate the potential of rIPC for increasing the physical performance of laboratory animals. The study was performed on 72 white outbred male rats. An assessment of the physical performance was carried out using a modiﬁed Porsolt test. The hind limbs of non-anesthetized animals were subjected to preconditioning. The results of a single and course (during 5 days) application of rIPC was evaluated. A single use of rIPC increased the average swimming time in the experimental group by 38.5%. The course application of rIPC did not lead to signiﬁcant changes in the indicators of physical performance in any of the animal groups.