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Monodisperse magnetofluorescent nanoplatforms for local heating and temperature sensing.

Monodisperse multifunctional MnFe2O4/dye/silica core/shell nanoparticles have been designed and developed. The magnetic cores act as nano-heaters in biological systems under RF field excitation and the encapsulated dyes work as local temperature probes. The silica shells enable the water-solubility and biocompatibility of the NPs and protect the encapsulated fluorophores from photobleaching.