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Epidemiological trends of HIV infection in Spain: preventative plans have to be oriented to new target populations (Spanish VACH Cohort).

This cohort study (VAHC cohort) was conducted to evaluate temporal changes of HIV infection in Spain. The study enrolled 4335 HIV-positive patients. Results showed that the percentage of women with new diagnoses of HIV infection had increased in the past 3 years, that sexual transmission has overtaken the injection drug use mode of transmission in Spain since 1998, and that the percentage of new HIV diagnoses is increasing in older people (> 39 years old).