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Severe manifestations of oculoauriculovertebral spectrum in a cocaine exposed infant.

Oculoauriculovertebral spectrum (OAV) is a caus- ally heterogeneous developmental field defect char-acterised by variable combinations of facial, ear, eye, and vertebral anomalies, which may be accompanied by cardiac, central nervous system, and other vis- ceral malformations. The disorder has a wide range of phenotypic expression, and right sided involve- ment is more common or more severe or both. We report a newborn with severe manifestations of this disorder who was exposed to cocaine prenatally. Oculoauriculovertebral spectrum in a cocaine ex- posed infant has not been previously reported.