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Sclerosis tuberosa and pregnancy.

OBJECTIVE
To perform a review of Tuberous sclerosis complex and its complications during the pregnancy from up to date scientific literature.


DESIGN
Complex systematic review of the literature.


SETTING
2nd Department of Obstetrics and Gynaecology, University Hospital Bratislava, Comenius University, Bratislava, Slovak Republic.


METHODS
Complex analysis of the syndrome, systematic search of MEDLINE and Slovak Medical Library. The reason to create a complex review of this syndrome was our clinical experience with one of the most acute lifethreatening condition of this syndrome - acute retroperitoneal haemorrhage in the pregnancy.


CONCLUSION
Tuberous sclerosis can cause a rare, but potentially lifethreatening complications, especially during the pregnancy. These should be carefully dispesarized and in complicated cases acute radical management should be considered.