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Topical Ruxolitinib for the Treatment of Alopecia Universalis.

Topical Ruxolitinib for the Treatment of Alopecia Universalis Alopecia areata and variants alopecia totalis and alopecia universalis are common conditions for which treatment options are limited. Oral Janus kinase (JAK) inhibitors have recently been shown to be effective for the treatment of these disorders. There are, however, risks for serious adverse effects with systemic therapy that may be avoided if topical therapy were an option.