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[Clinical value of determining spontaneous chemiluminescence of neutrophils in young children with meningococcal infection].

The generalized meningococcal infection in infants in frequently associated with changes (mostly with an increase) in neutrophil reactivity, which can be identified with the aid of spontaneous luminol-dependent chemiluminescence (CL) of diluted blood. The changes in the functional activity of neutrophils mirror the adequacy of the reaction to the meningococcal infection, which turns out maximal in the patterns of medium gravity. The low indicators of CL serve as a prognostic criterion for an unfavourable course of the meningococcal infection, which requires early immunocorrective treatment.