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[Study on inhibition on alpha-glucosidase and analysis of the hypoglycemic composition of lobster sauce].

OBJECTIVE
To study the effects of lobster sauce and polysaccharide extracts on alpha-1,4-glucosidase activity by establishing on enzyme-inhibitor model.


METHODS
Glucosidase activity was assayed at PH optima by PNPG substrate. Lobster sauce extracts were prepared by soaking, centrifagation. Polysaccharide were prepared by soaking, centrifagation, separation.


RESULTS
Lobster sauce and polysaccharide can inhibit alpha-1,4-glucosidase.


CONCLUSION
This finding suggested that their hypoglycemic mechanism was similar to Acarbose. Lobster sauce may contain phenyalanine.