{'fraction_non_alphanumeric': 0.040110650069156296, 'fraction_numerical': 0.009681881051175657, 'mean_word_length': 6.029126213592233, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
Single nuclei RNA‐seq data analysis identifies glial cell lineages associated with Alzheimer’s disease severity

Single nucleus RNA sequencing (snRNA‐seq) has the potential to improve our understanding of the cellular‐specific drivers of sporadic Alzheimer’s disease. In this study we re‐analyze published snRNA‐seq data from post‐mortem dorsolateral prefrontal cortex tissue from 48 participants in the Religious Order Study and Memory and Aging Project (ROS/MAP) cohorts (Mathys et al. 2019) and snRNA‐seq data from prefrontal cortex tissue from 9 participants across the Adult Changes in Thought (ACT), University of Washington Alzheimer’s Disease Research Center (UW‐ADRC), and Seattle Longitudinal Study (SLS) cohorts.