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Carbon dioxide (CO2) laser perforation of exposed cranial bone to stimulate granulation tissue.

The technique of CO2 laser perforation of exposed bone has been discussed. The advantages of this rapid and safe technique, which minimizes patient anxiety, limits tissue destruction, and can be performed without anesthesia in an outpatient setting, suggest that it can be considered as a possible alternative treatment to stimulate the production of granulation tissue over exposed bone to allow healing by secondary intention or skin grafting.