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First‐trimester diagnosis of hydrolethalus syndrome

At 12 weeks of gestation, a combination of atypical hydrocephalus with absent mid‐line structures and club foot was detected during transvaginal ultrasound examination. These findings were diagnostic of hydrolethalus syndrome and were confirmed after subsequent termination of the pregnancy. This is the first known case of first‐trimester prenatal diagnosis of hydrolethalus syndrome. Copyright © 1995 International Society of Ultrasound in Obstetrics and Gynecology