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Opioid Induced Achalasia Treated with Naloxegol: A Case Report

The chronic use of opioids may result in opioid induced consti- pation and disordered esophageal motility (achalasia). Patients who experience achalasia will experience nausea, vomiting, anorexia and weight loss which could complicate treatment of their opioid disorder. Naloxegol (a partial μ antagonist) is FDA approved to treat patients with opioid induced constipation. We report a single case of severe opioid induced achalasia successfully managed with naloxe- gol for 30 days.