{'fraction_non_alphanumeric': 0.03889789303079417, 'fraction_numerical': 0.031874662344678555, 'mean_word_length': 4.6984615384615385, 'pattern_counts': {'":': 0, '<': 3, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
The effects of incremental whole beetroot consumption on plasma nitrate and nitrite levels and blood pressure in young and old subjects

Nitric oxide (NO) is produced in the body endogenously or through the breakdown of exogenous dietary nitrate, and has been found to reduce blood pressure (BP) and improve endothelial function. The richest sources of dietary nitrate come from vegetables such as radish, rocket and beetroot, the latter of which has been supplemented in a variety of forms, most commonly as a juice. This study investigated the effects of whole beetroot on BP following incremental doses in a young and old population, and compared the effects to a positive control. We hypothesised that there would be a nitrate dose-dependent response in BP, and that the old would have a reduced response to these doses in comparison with the young. Additionally, we hypothesised that there would be a direct association between changes in BP and plasma nitrate and nitrite concentrations. In this randomised, crossover trial, 12 adults aged 18-35 and 12 adults aged 60-75 consumed either 100g, 200g, or 300g whole beetroot or a 1g potassium nitrate solution (PN) on four separate occasions, and BP was assessed over a five-hour period following consumption. Results showed that for systolic BP, there was no significant effect of trial, but a significant effect of time (p = 0.034) and a time*age interaction (p = 0.013). There was a significant effect of time (p < 0.001) and a significant age effect on diastolic BP (p = 0.025) (Figure 1). Results also show that there was a dosedependent increase in nitrate and nitrite plasma concentrations and greater increases in plasma nitrite concentrations were associated with a greater decrease in both systolic (n = 288, r=−0.28, p < 0.001) and diastolic (n = 288, r=−0.25, p < 0.001) blood pressure.