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Improved Nerve Regeneration With Neutralization of Transforming Growth Factor‐β1

Objectives: Recovery of injured peripheral nerves depends on a balance between Schwann cell regeneration and scar formation. Transforming growth factor‐β1 (TGF‐β1) has been implicated as a humoral stimulus in scar formation. The neutralization of TGF‐β1 has been beneficial in the reduction of fibrosis. This study was to identify the presence of TGF‐β1 in regenerating peripheral nerve and to measure motor nerve regeneration by the neutralization of TGF‐β1 in neural wounds.