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The sensitivity of Amsler grid testing in early chloroquine retinopathy.

Amsler field testing of patients treated with chloroquine and hydroxychloroquine is simple, rapid, reproducible and sensitive. Amsler testing will readily detect small relative paracentral scotomas. Four cases of irreversible bilateral scotomas were detected in 8 eyes of 4 patients with normal static and kinetic fields in 7 of the 8 eyes. Kinetic and static fields on a subsequent examination demonstrated the bilateral paracentral scotomas first detected with the Amsler grid.