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Destructive Eyelid Lesions in Sarcoidosis

Purpose To report the clinical and histopathologic findings of a patient with sarcoidosis causing bilateral destruction of the lower eyelids. Methods Case report. Results Bilateral destructive lower eyelid lesions and cicatricial entropion developed in a 43-year-old man with systemic sarcoidosis. Histopathology was consistent with sarcoid granulomas. Disease progression was arrested with systemic prednisone and methotrexate before eyelid reconstruction was performed. Conclusions Sarcoidosis very rarely can cause destruction of full-thickness eyelid architecture. Active inflammation should be controlled before reconstruction.