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Comment to: Disease aetiology-based design of multifunctional microemulsion eye drops for moderate or severe dry eye: a randomized, quadruple-masked and active-controlled clinical trial

Sacha inchi (Plukenetia volubilis) is an oil plant native to tropical rainforests in South America. The seeds of the plant are a potential source of macro- and microelements, α-linolenic acid and phytochemicals. 
A single-centre, prospective, masked clinical study was designed to investigate the efficacy and safety of multi-ingredient sacha inchi microemulsion (SIME) eye drops in the treatment of patients with dry disease. 
Sacha inchi microemulsion (SIME) proved safe and efficacious in re-establishing the physiological protective tear film function and restoring the homeostasis of the ocular surface.