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[Successful treatment of children with leukemia diagnosed 1966-72. A follow-up 23-29 years after diagnosis].

Childhood leukemia was considered an incurable disease up to the beginning of the 1970. However, before 1976 we discontinued therapy in remission in 13 (30%) of 43 new cases of acute lymphocytic leukemia/acute undifferentiated leukemia diagnosed in the period June 1966-December 1972. One of the 13 cases relapsed after three years and the other after 14 years. Both were successfully retreated. One received intermediate dose metotrexate (0.5 g metotrexate/m2), the other high dose metotrexate (8 g metotrexate/m2) as consolidation. All 13 cases were healthy at the time of follow-up in the autumn of 1994. One testis had been removed in a case with initial testicular involvement and testicular relapse. No other definite late effects were diagnosed following treatment for childhood leukemia in the 13 cases. The article also contains information on health and socioeconomic status. The mean height of the six males was 183 cm, and of the seven females 170 cm. Nine of the 13 lived with a partner, one alone and three with parents.