{'fraction_non_alphanumeric': 0.013986013986013986, 'fraction_numerical': 0.000999000999000999, 'mean_word_length': 5.816326530612245, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
BESPA: Software Tools for Three-Dimensional Structure Reconstruction from Single Particle Images of Proteins

Single particle analysis is a straightforward method for structural studies of protein and biological macromolecules developed in image analysis on electron microscopy [1]. It is a predominant structural probe for proteins which decline to crystallize and exceed the limit in molecular weight for NMR analysis. Furthermore, it allows to examine structural changes and molecular complex of proteins at work, which will become a great advantage for the next generation in structural biology after static structures of proteins are all determined. Our system, named BESPA (Backplane for Electron microscopic Single Particle Analysis) will be packaged soon featuring new algorithms and techniques together with practically useful programs. The single particle analysis has also raised topics for a computational science both in practical algorithm and in establishment of theoretical background.