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Pharmacokinetics Of Organic Anions In Rats With Arterial Calcinosis

1. Ageing induces calcium accumulation in the vascular system. The simplest experimental way of producing high degrees of arterial calcium overload is by admininistration of an overdose of vitamin D3 to rats. The aim of the present study was to evaluate the pharmacokinetics of organic anions in rats with arterial calcinosis induced by an overdose of vitamin D3.