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Use of Adenosine Test for the Exclusion of Preexcitation Syndrome in Asymptomatic Individuals

Background: Resting electrocardiogram is a routine procedure for the identification of potentially fatal conditions, including preexcitation syndrome (PES). Intravenous adenosine is a sensitive and specific means of exposing inapparent pathways in such patients. Yet, it may not be sensitive when complete atrioventricular (AV) block is not achieved because a low dose of adenosine is used. We evaluated the yield of a high‐dose adenosine test that achieved complete AV nodal block for unmasking inapparent pathway in a healthy population.