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[A 10 years review of the characteristics of in-hospital ventricular fibrillation victim in a single center].

OBJECTIVE
To study the factors influencing the outcome of patients suffering from in-hospital ventricular fibrillation (IHVF), as there have been few studies focusing on this topic.


METHODS
Patients with IHVF collected in a single cardiac center were classified into a successful group and a failure group. Data relevant to the predicting factors of the two groups were compared.


RESULTS
There were 206 events in the analysis. The most common underlining disease was coronary artery disease (CAD), especially acute myocardial infarction (AMI). On multiple logistic regression analysis, it was shown that the independent predictors for failure of defibrillation were higher NYHA class (OR 1.7, 95% CI 1.3 - 2.2, P < 0.001), higher blood potassium level (OR 2.9, 95% CI 1.9 - 4.3, P = 0.007) and adrenaline usage (OR 25.0, 95% CI 11.5 - 55.1, P < 0.001). In a AMI sub-group, 56.9% of the IHVF events occurred within the first day of AMI, and the occurrence descended with time going on within 2 weeks. Before the occurrence of IHVF, the patients with right coronary artery as the infarction related artery (IRA) often suffered from (8/9, 88.9%) bradycardia (R-R interval > 1 s), but those with left anterior descending artery as IRA often showed (8/12, 66.7%) tachycardia (RR interval < 0.6 s).


CONCLUSIONS
The common disease causing IHVF is CAD. The worse the heart function, the higher the rate of IHVF and the worse the prognosis. It IHVF not induced by hypokalemia and use of adrenaline in resuscitation predict lower successful defibrillation rate.