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Bioactive and Degradable Composite Microparticulates for the Tissue Cell Population and Osteogenic Development

Bioactive and degradable composite microspheres (bioactive glass-synthetic biopolymer) were produced to deliver tissue cells and to aid their osteogenic development targeted for hard tissues. Cellular population (left, SEM cell image at day 3) and osteoblastic differentiation (right, immunofluorescence staining with bone marker at day 14) on the microspheres was evident, suggesting the composite microspheres provided effective 3D substrate conditions for hard tissue regeneration.