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726 BIOAVAILABILITIES OF CALCIUM (CA) AND PHOSPHORUS (P) ARE HIGHER IN FORTIFIED MOTHER'S MILK COMPARED TO COMMERCIAL FORMULA

Bioavailabilities of Ca and P in human milk and commercial formula preparations have not been assessed at similar levels of nutrient intakes. In this study, the utilization of Ca and P was compared during the first two postnatal mo in 2 groups of preterm infants fed either fresh mother's milk fortified with lyophiiized human milk skim fractions and added Ca lactate and P salts (Group FM, birthweight, 1088 ± 53 g; gestation 28 ± 0.3 wk, Mean ± SEM) or a commercial formula designed for preterm infants (Group CM, 1057 ± 49 g; 29 ± 0.2 wk). Two 96-h balance studies were conducted at wk 3 and 7. Similar daily intakes were maintained in both groups: Ca 112 ± 2, P 68 ± 3, and nitrogen 486 ± 6 mg/kg and energy 129 ± 1 kcal/kg.Net Ca retention and absorptions of Ca and P were higher for group FM. The ratio and absolute values of Ca/P retention observed in Group FM approximated estimates of fetal retention more closely than those in Group CM. These results indicate that despite similar levels of intake for both groups, the bioavailability of Ca and P in FM was higher than in CM and that Ca and P adequacy can be maintained in preterm infants for two months when they are fed FM.