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PROSTAGLANDIN F2α CONCENTRATIONS IN AMNIOTIC FLUID IN LATE PREGNANCY

Prostaglandin F2α (PGF2α) was assayed in samples of amniotic fluid obtained at 185 to 298 days gestation. Before 252 days (36 weeks) values below 75 pg./ml. were found in 20 of 22 samples. After 252 days but before the onset of labour 80 per cent of values exceeded 300 pg./ml., with a progressive rise with advancing gestation. During the first stage of labour a further rise in values occurred.