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Use of Coagulant Spray Glue (Glubran 2®) for Aerostatic Purposes in Pulmonary Parenchyma Resections in Pigs: A Preliminary Study

Background: The aim of our study was to test the aerostatic validity of a cyan-acrylic glue (Glubran 2®), applied by means of a spray catheter, on an experimental pig model. Materials and Methods: 15 young pigs were divided into three study groups of 5 based on surgical techniques: (1) atypical pulmonary resection with mechanical suturing and reinforcement with continuous suturing; (2) resection of the pulmonary parenchyma with a cold scalpel, followed by local application of Glubran 2; (3) atypical pulmonary resection with mechanical suturing followed by application of Glubran 2. Results: The mean aerostasis time was calculated at 3.5 ± 1.26 s. The histopathological analysis did not show any particular differences when comparing the effects of the treatments carried out with Glubran 2 spray glue and the standard treatments. No statistically significant differences were recorded in the short- and medium-term survival of pigs treated with Glubran 2 compared with the respective control groups. Conclusions: The application of Glubran 2 spray on wounds caused by pulmonary resections in pigs proved to have a rapid and effective influence for the purposes of aerostasis without significant differences in air losses and survivals.