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Emerging concepts in monoclonal gammopathy of undetermined significance.

Monoclonal gammopathy of undetermined significance (MGUS) is frequently diagnosed in the elderly population. Most physicians will have to evaluate and manage patients with this condition. Recent studies have clarified risk factors, natural history, prognosis and complications of this common condition. This short review discusses basic concepts and recent developments that will facilitate the diagnosis and management of this condition by primary care physicians and specialists in other areas of medicine.