{'fraction_non_alphanumeric': 0.018167456556082148, 'fraction_numerical': 0.011848341232227487, 'mean_word_length': 5.335, 'pattern_counts': {'":': 0, '<': 0, '<?xml version=': 0, '>': 0, 'https://': 0, 'lorem ipsum': 0, 'www.': 0, 'xml': 0}, 'pii_count': 0, 'substrings_counts': 0, 'word_list_counts': {'cursed_substrings.json': 0, 'profanity_word_list.json': 0, 'sexual_word_list.json': 0, 'zh_pornsignals.json': 0}}
P25An alobar holoprosencephaly; a case report

Alobar holoprosencephaly characterised by median malformations of the face and brain due to incomplete cleavage and morphogenesis of the fore brain. The alobar holoprosencephaly occur in about 0.6–1.9 of 10.000 deliveries. Median facial abnormalities consist of orbital hypotelorizm, cyclopia in combination with a flat nose or proboscis and oral deformities can be diagnosed with ultrasonographicaly at the early antenatal period. In this case report we introduced a fetus with an alobar holoprosencephaly diagnosed at 24 weeks of gestation according to BPD and FL measures. In obstetric ultrasonography, spinal cord, vertebras and spinal canal were normal in structure, but interhemispheric fissure, falx cerebri and corpus callosum were not visualised. There was single‐chamber ventricle in semihiron shape that continued with a dorsal cyst filing the calvarium. Decision for pregnancy termination was made after the consultation with the pediatricians. In neonatal examination, there was no gross deformity of the trunk and extremities. As a facial deformity, cyclopia and 3 × 2 cm sized proboscis attacked above the insignificant nasal structure was detected and only one eye was present at the middle of the face.