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Enzymic biomedical research and new drug development

The proceedings of a symposium on current trends in enzyme‐guided biomedical research and its relation to potential new drug discovery are reviewed. Topics under discussion include current concepts in enzyme inhibition, the mechanism and inhibition of phopholipase A2, 5‐lipoxygenase and inflammation, the protease/antiprotease hypothesis of emphysema, carbonic anhydrase and glaucoma, GTP‐binding proteins and adenylate cyclase, and the calpain hypothesis of memory storage.