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Mechanical properties of skin in recombinant human growth factor abusers among adult bodybuilders.

A Cutometer was used to measure the mechanical properties of skin in 8 adult bodybuilders who were recombinant human growth hormone (hGH) abusers. Although skin deformability and biological elasticity remained within the normal range, an increase in dermal viscosity was noted. The expression of the activity of hGH or insulin-like growth factor I on target dermal cells is likely to be responsible for these findings.