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Pregnancy Testing of Adolescents during Clinical Research: Managing the Process.

Pregnancy testing is often required for participation in clinical research, but little published literature addresses the special issues that arise when adolescents who are not legal adults (minor adolescents) are eligible to participate in such research. Below, we set forth a framework for how such testing should be managed, drawing on considerations of ethics, law, and adolescents’ developmental cognitive capacity to make decisions about research participation and medical care.