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Molecular biology of the human foamy virus.

Foamy viruses also known as spumaretroviruses are complex retroviruses infecting cell lines with no apparent specific cellular tropism and induce the formation of multinucleated cells with numerous vacuoles. Far less well characterized than oncoviruses and lentiviruses, this class of viruses is thought to be innocuous in vivo. However, several important discoveries on foamy viruses brought new insights in the field of retrovirology.