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A CLINICAL STUDY TO EVALUATE THE EFFICACY OF GUDUCHYADI TAILA MATRABASTI IN VANDHYATWA W.S.R. TO ENDOMETRIAL RECEPTIVITY

Infertility is a public health issue in India and many other developing countries because of its high prevalence and especially due to its serious social implications. According to the data of WHO, more than 180 million couples in developing countries agonise from primary or secondary infertility. The social stigma of childlessness still leads to isolation and abandonment in many communities. Although there is a lot of advancement in infertility care, the availability, affordability and effectiveness are still very low. Ayurveda described the disease vandhyatwa as equivalent to infertility. In Ayurveda, the management of Vandhyatwa mainly focuses on the correction of garbha sambahava samagris. Kshetra which is one among them is considered as the prime factor for conception. Kshet- ra can be taken as the female reproductive system, a well-prepared endometrium for implantation. Optimal en- dometrial receptivity leads to proper implantation of the embryo, which is the foundation of a healthy pregnancy. Implantation failure due to reduced endometrial receptivity is one of the major causes of infertility. In this present study, the endometrial receptivity was assessed with Applebaum's uterine score and Guduchyadi taila matrabasti has been administered to increase the receptivity of the endometrium. After the intervention, the results obtained showed significant improvement in endometrial receptivity.
Keywords: Vandhyatwa, Applebaum's scoring, Matrabasti, Guduchyadi taila