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Drug therapy of ulcerative colitis.

The management of patients with ulcerative colitis has been well established since the trials of corticosteroids and sulphasalazine in the 1950s and 60s. However, the last decade has seen the introduction of a variety of new steroids, salicylates, immunosuppressive agents and other compounds directed against specific inflammatory mediators. In this review we will attempt to define the place of the many drugs now used in ulcerative colitis.