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Distribution and control of some genetic disorders.

The health burden of genetic disorders varies between ethnic groups within the same country or between countries to a large extent because of genotypic differences at the population level. Genetic services should recognize this variability in need and be developed within the traditional context of medical care. All practical approaches require a sound epidemiological basis and underline the importance of early diagnosis for both prevention and treatment. Effective control is now possible for some Mendelian conditions and some congenital malformations and should be incorporated into general health care. The development of genetic services within any country depends on the optimal utilization of available resources, both financial and intellectual.