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Is cytology or HPV testing more effective for detecting high-grade cervical dysplasia in average-risk, asymptomatic women?

A positive human papillomavirus test is more sensitive than cervical cytology for detecting histologically confirmed cervical intraepithelial neoplasia grade 2 or higher, leading to fewer false-negative results. Cervical cytology is slightly more specific leading to fewer false positives (SOR: A, systematic review, randomized controlled trial). Copyright © 2019 by Family Physicians Inquiries Network, Inc. DOI 10.1097/EBP.0000000000000542