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Sleep by actigraphy in patients with remitted bipolar disorders

orders. It relies on developmental plasticity, the capacity of genotype to yield different phenotypes in response to environmental conditions (3). Nevertheless, the idea of creativity as an adaptive tool towards survival in mental health viewed from an evolutionary point of view remains quite controversial, although early ‘diversifying experiences’ (4) have been already proposed to underlie creativity. In our proposal, we argued with empirical data (abnormal glycemic homeostasis in na€ıve patients) about the possibility of a translational hypothesis from general medicine into mental health. The plausibility of creativity and mental disorders still require a specific neurocognitive pathway to be proven (5), although the issue reflects the powerful capacity of psychiatric disorders in widening the understanding of the brain function. Major psychiatric illnesses represent an excellent opportunity for humankind to understand the basis of diverse patterns in human physiology. Doctor Hubbeling’s speculation about an evolutionary trade-off towards creativity after early life stressors highlights the need of further translational efforts into mental health.