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Case of alopecia areata during dupilumab treatment for atopic dermatitis

incidence of autoimmune disease may be rising, generally. Although the exact causality is unclear, commonly shared genetic predispositions and the mutual effect of autoinflammation may influence the pathogenesis of one another. The incidence increase may also be attributed to improved disease awareness leading to early diagnosis. A total of 7933 patients were newly registered as AA, among whom 3975 were men and 3958 were women. A total of 219 patients were newly registered as either AT or AU, among whom 102 were men and 117 were women. Both sexes displayed similar susceptibility to AA and AT/AU. The age distribution of AA and AT/AU resembled a bell-shaped curve peaking at the age of 30–39 years (Fig. 1c,d). To the best of our knowledge, this is the first nationwide, population-based epidemiological study of AA in the Asian population. The large cohort size and the long observation period are the strengths of this study. Our results demonstrate an increase in the frequency, especially in milder forms of AA, and may provide data for health utilization projections in the future.