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Computer analysis of portal hemodynamics after portacaval shunt

In this study we performed an analysis of portal hemodynamic after partial shunting using the Wheatstone bridge model of the splanchnic circulation. The model was modified to include a variable resistance for a portacaval shunt and was programmed as a computer simulation. Simulation results demonstrate that if the portacaval pressure gradient is diminished below 1/3 of the initial value after portacaval shunt, the inversion of the portal flow will be made. The portacaval pressure gradient after shunting, in pratice should be maintained at 2/3 of the initial value. These predictions were confirmed by clinical observations in 35 patients undergoing portacaval shunt.