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Induction of Immune Reaction in Benign Melanocytic Nevi Without Halo During Nivolumab Therapy in a Patient With Melanoma.

Induction of Immune Reaction in Benign Melanocytic Nevi Without Halo During Nivolumab Therapy in a Patient With Melanoma Immune reactions in benign melanocytic nevi (BMN) without halo phenomenon are extremely rare, although humoral and cellular immune responses are involved in their development. Herein, we report a rare case of a patient with metastatic melanomas who showed a remarkable clinical response to nivolumab with a simultaneous prominent immune reaction in multiple BMN without halo phenomenon.