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Experimental social rejection increases dyspnoea perception and neural processing of respiratory sensations in healthy subjects

Patients suffering from dyspnoea frequently report social rejection as a severe limitation of their lives [1]. While the effects of different social challenges on the respiratory system are already established in animal models [2, 3], little is known about potential consequences of social rejection on the perception and neural processing of dyspnoea in humans. Detrimental effects of social rejection are well documented for other aversive somatic symptoms [4, 5]. The current study examined whether social rejection would increase perceived dyspnoea and whether this would be paralleled by increased neural processing of respiratory sensations as measured with respiratory-related evoked potentials (RREPs) in the electroencephalogram (EEG). Social rejection is associated with increased dyspnoea perception and neural processing of respiratory sensations http://ow.ly/p5hA30mcZMS