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Circulating Malignant Cells and Fibrinolysis during Resection of Colorectal Cancer

It has been suggested that circulating malignant cells which cannot implant could have a favourable prognostic significance and that the absence of such cells might represent a condition in which rapid implantation had occurred. Furthermore it has been suggested that circulating malignant cells were not associated with any worse outlook in cancer of the rectum cases at five years. Naturally occurring fibrinolytic activity is known to lead to the appearance of cells in the peripheral blood (Griffiths et al. 1973).