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Molecular Delivery: Rapid, High-Throughput, and Direct Molecular Beacon Delivery to Human Cancer Cells Using a Nanowire-Incorporated and Pneumatic Pressure-Driven Microdevice (Small 46/2015).

A nanowire-incorporated and pneumatic pressure-driven microdevice for rapid, high-throughput and direct molecular beacon (MB) delivery is described by I. Park, T. S. Seo, and co-workers. On page 6215, they show how the microdevice, composed of a manifold layer, a monolithic PDMS membrane, and a nanowire-patterned microchannel layer, could manipulate cellular movement, so the attachment and detachment from the MB-functionalized nanowire array is performed in a controllable way to increase MB delivery efficiency.