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A Review of Its Properties and Current Status in Nuclear Medicine

While working with gallium-67 citrate (Ga-67) as a bone seeking isotope, Edwards and Hayes 1 noted that this isotope of gallium concentrated in the lymphomatous nodes of a patient with Hodgkin's disease. This original observation was followed by a more extensive study in 1970 which demonstrated Ga-67 accumulation in 23 of 41 cancer patients." Since then, many investigators3 -13 have reported their experience with Ga-67 scanning and have offered various explanations for its uptake by tumors. It is the purpose of this paper to review the characteristics of Ga-67, report our experience, and discuss its role in clinical practice.