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[Research on monoamine oxidase inhibitors: synthesis of N-alkyl and N-aralkyl substituted ethylsyringoylhydrazides].

In continuation of previous work on compounds with anti-MAO activity, some alkyl and aralkyl-hydrazides of ethylsyringic acid (3,5-dimethoxy-4-ethoxybenzoic acid) were synthesized. Pharmacological examination showed that branching of the alkyl radical on the beta nitrogen to the carbonyl group increases anti-MAO activity which appears to be linked with the molecular dimensions of the alkyl group.