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NMR Imaging of Laboratory Mice at 2 Tesla: A Non-invasive Insight into Normal Anatomy

Many anatomical features of the mouse which are of interest in developmental biology, lie in the sub-millimetre range and can be visualised by NMR imaging at 2 Tesla (T) with spatial resolution in the range of 180–250μm for a slice thickness of 1–1.5mm. Using surface coils to localise a region of interest close to the surface, a resolution as high as 100μm can be achieved. It is possible to obtain a series of up to 20 slice images with a total imaging time of less than 30 minutes.