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Olfactory brain gray matter volume reduction in patients with chronic rhinosinusitis

Chronic rhinosinusitis (CRS) is a common inflammatory condition and a major cause of olfactory loss. Olfactory dysfunction has been associated with reduced olfactory bulb (OB) volume and gray matter (GM) density in the olfactory‐related brain areas. The aim of this study was to investigate brain GM structural and OB volume alterations in patients with CRS.