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Sjögren’s Syndrome and The Respiratory System: A Comprehensive Approach

Sjögren’s syndrome (SS) is an autoimmune connective tissue disease characterized by lymphocytic infiltration of exocrine glands leading to progressive inflammation and destruction. This condition mainly involves the lacrimal and salivary glands and is associated with development of the classic dry eyes and mouth1. Additionally, an estimated third of the population develops extra-glandular manifestations involving the cutaneous, cardiovascular, neurologic, renal, pulmonary, and musculoskeletal system2,3.