Bupropion This is great for smoking cessation but seems rather uneffective as an anti-depresent. Wasn't this stuff invented light years ago? It is cheap, I'll give it that, but like any other stimulant you get some nasty side-effects on anything higher than 150 mg per day (at least I do). Perhaps it is good for mild depression as it gives you a bit of an elevated mood, but the GI problems and tremors I got certainly weren't worth it. Once again, if you want to quit smoking and nothing else will do it, this is your ticket, but as an anti-depressent I give it a thumbs down.