OH  ~I  ~  0  oyo~~  I  O  I  ~  #’  •’t;---4  O=C  C=O  I  I  d  o°’s~  (CO  OH  oyo~  I  SH  OH  OH  ~I  ":yo~Ni~D)  •~•  c=o  I  0  O~SO3  H  N~OH  ~SYTI  v------v  US 8,852,845 B2  156  155  -continued  -continued 