Oct. 21, 2010  47  US 2010/0266955 Al  [Chemical Formula 54]  (b0-01)  (b0-02)  (bl-2)  -continued  (b0-1-1)  [Chemical Formula 53]  (b0-1-01)  (b0-1-02)  (b0-1-03)  (b0-1-0)  (1-3)  [Chemical Formula 55]  In the formulas, X, Q 2 ,  Y $^{1 }$and M+ are respectively the same as  defined for X,  Q 2 ,  Y 1  and M+ in formula (b0-1); and  Xh  represents a halogen atom.  [0394]  The reaction between the compound (b0-1) and the  compound (b0-2) can be effected by dissolving the com› pounds in a solvent such as water, dichloromethane, acetoni› trile, methanol, chloroform or methylene chloride, followed  by stirring.  [0395]  The reaction temperature is preferably Oto 150°  C.,  and more preferably O to 100°  C. The reaction time varies  depending on the reactivity of the compound (b0-1) and the  compound (b0-2), the reaction temperature, and the like.  However, in general, the reaction temperature is preferably  0.5 to 10 hours, and more preferably 1 to 5 hours.  [0396]  In general, the amount of the compound (b0-2) used  in the reaction is preferably 0.5 to 2 moles, per 1 mole of the  compound (b0-1).  [0397]  [Production Method of Compound Represented by  General Formula (bl-2)]  [0398]  A compound represented by general formula (bl-2)  above can be produced by a method including reacting a  compound (b0-01) represented by general formula (b0-01)  shown below with a compound (b0-02) represented by gen› eral formula (b0-02) shown below.  (1-1)  (1-2)  In the formulas,  R, R 21 , Y $^{1 }$and M+ are the same as defined  above; and X$^{22 }$represents a halogen atom.  [0401]  Examples of the halogen atom represented by X 22  include a bromine atom, a chlorine atom, an iodine atom and  a fluorine atom. In terms of reactivity, a bromine atom or a  chlorine atom is preferable, and a chlorine atom is particu› larly desirable.  [0402]  As the compounds (1-3) and (2-1), commercially  available compounds may be used, or the compounds may be  synthesized.  [0403]  A preferable method of synthesizing the compound  (1-3) includes reacting a compound (1-1) represented by gen› eral formula (I-1) shown below with a compound (1-2) rep› resented by general formula (I-2) shown below, thereby  obtaining a compound (1-3).  [Chemical Formula 56]  0  II  HO-R $^{2}$Lo-C-Y$^{1}$-S03- M+  (2-1)  0  II  Rx-c-x22  In the formulas, R$^{02 }$represents an alkyl group ofl to 5 carbon  atoms; and X,  Q 2 , Y 1  and M+ are respectively the same as  defined for X,  Q 2 ,  Y $^{1 }$and M+ in formula (b0-1).  [0392]  Alternatively, for example, silver fluoride, a com› pound represented by general formula (b0-1-01) shown  below and a compound represented by general formula (b0- 1-02) shown below can be subjected to a reaction in an  organic solvent such as diglyme anhydride to obtain a com› pound represented by general formula (b0-1-03) shown  below. Then, the compound represented by general formula  (b0-1-03) can be reacted with an alkali metal hydroxide such  as sodium, hydroxide or lithium hydroxide in an organic  solvent such as tetrahydrofuran, acetone or methyl ethyl  ketone, thereby obtaining a compound represented by general  formula (b0-1) above in which mO is O (i.e., a compound  represented by general formula (b0-1-0) shown below).  [0393]  In general formula (b0-1-02), as the halogen atom  for  Xh,  a bromine atom or a chlorine atom is preferable.  In the formulas,  Rx  represents an aliphatic group which may  have a substituent ( excluding a nitrogen atom); R $^{21 }$represents  an alkylene group; Y$^{1 }$represents an alkylene group of 1 to 4  carbon atoms or a fluorinated alkylene group of 1 to 4 carbon  atoms; M+ represents an alkali metal ion; A+ represents an  organic cation; and z- represents a non-nucleophilic ion.  [0399]  In the formulas,  Rx,  R  21 , Y1, M+, A+ and z- are the  same as defined above.  [0400]  The aforementioned compound (b0-01) can be syn› thesized, for example, by reacting a compound (1-3) repre› sented by general formula (1-3) shown below with a com› pound (2-1) represented by general formula (2-1) shown  below.  HO-R$^{2}$1-0-R 22 