Edwards introduced the practice of hemodynamic monitoring with the first Swan-Ganz catheter in the 1970s, and we continue to pave the way with new technologies that enhance diagnostic capabilities in critical and intensive care. Our latest critical care innovation, the PreSep central venous oximetry catheter, is part of an important new medical regimen to address sepsis, the spread of an infection that may lead to multi- organ failure and is the leading cause of death in non-coronary intensive care units.  A study recently published in the  New England Journal of Medicine found that this  new medical regimen, including use of the central venous oximetry catheter to perform  early monitoring of a patient’s oxygen saturation (ScvO $_{2}$) and other hemodynamic  parameters, resulted in dramatic reductions in patient mortality and treatment costs. S22