U.S.  Patent  Feb.28,2017  Sheet 17 of 23  US 9,583,325 B2  Fig, 17  _.  Minature Probe  .----P•E•E•K111111T11111Ms•o•1•v•en•t•L•i•ne•s- ... Interface  Flow Divert  Degassed  Acceptor  Phase Supply  Reservoir  Acceptor Phase  Delivery Capillary  PDMS Hollow  Fibre Membrane  Co-Axial Acce~tor  ,,,,.  Phase Flow  Wire Wraps  Stainless Steel Plug  _..  Valve  ,... __  111(,...._._i,;-----:,r  In-Line  Micro Pump  Sample  Vial  t  Direct  Mixing  "  Infusion  ~~::~~~!~~ospray  ~  Trip:~~~ge  Capillary  l I Quadrupole  Tandem  Mass  Spectro› meter  Note: Not to Scale 