Consolidated Statements of Operations Year Ended December 31, 2001 2000 1999 (in thousands, except per share amount) Revenue: Contract revenue $ 1,224 $ 1,194 $ 30 License revenue 2,600 415 50 Grant revenue 748 271 257 Total revenue 4,572 1,880 337 Operating expenses: Research and development 23,339 16,744 9,429 Acquired in-process research and development — 4,969 136 General and administrative 5,383 4,070 2,794 Total operating expenses 28,722 25,783 12,359 Loss from operations (24,150) (23,903) (12,022) Other income (expense): Interest income 6,763 5,156 756 Other expense (77) (41) (30) Other income, net 6,686 5,115 726 Net loss $(17,464) $(18,788) $(11,296) Basic and diluted net loss per share $ (0.63) $ (0.73) $ (0.70) Weighted-average shares used in computing basic and  diluted net loss per share 27,595 25,591 16,112 See accompanying notes. Nineteen