improve the information provided to risk managers and citizens through the risk assessment  process. 4  • Increases researchers’ interest in regulatory risk assessment science. Will strengthen EFSA’s  direct links with research communities working on the new decade of toxicology and EFSA’s  role as EU knowledge hub, connecting researchers, risk assessors and risk managers, for  integrating novel scientific tools and knowledge in comprehensive chemical risk  characterisations. By introducing modern methods for risk assessment into its daily work,  EFSA becomes an increasingly attractive place for employment for both high level and early  career scientists and for external experts recruited to Panels and working groups  • Positions EFSA as an important partner for the implementation of NAMs in regulatory science  for hazard and risk assessment of chemicals in food and feed at EU level, and internationally.  The involvement of ECHA and other EU agencies should be also considered in anticipation of  the One substance - One assessment approach, that will need inter-agencies alignment on  the regulatory use of NAMs. Demonstrates EFSA’s contributions to societal needs and  reduction of animal testing, with increased visibility of EFSA commitment to stimulate the  use of NAMs and to reduce, refine  and replace animal testing. Enhancing EFSA’s role and  position in the area of NAMs internationally through bilateral agreements and multilateral  platforms such as APCRA, IFCSLG, GCRSR, WHO’s Chemical Risk Assessment Network and  ILMERAC. • Facilitates the application of NAMs in chemical risk assessment by EFSA and at EU level.  Significant reduction in the need for using animals for conducting verification studies, by  increasing EFSA’s scientific capability in the application of NAMs for chemicals in food,  particularly for addressing data gaps in the risk assessment instead of requesting additional  animal testing. This will include the harmonisation through a cross-cutting guidance on the  use of NAMs, and the update of the sectoral guidances in order to adapt the  recommendations to the regulatory requirements. • Prepares the pathway for better and more informative risk assessments; using new  toxicological tools and mechanistic information. Chemical risk assessment will be improved  through an updated paradigm, allowing risk managers to take informed decisions to protect  susceptible subgroups of the EU population.  • Specific cooperation lines will be established with the future European partnerships under  Horizon Europe, such as the abovementioned European Partnership for the Assessment of  Risk from Chemicals (PARC) which aims to start in 2022. These partnerships may be  considered for funding innovative research projects which may support the development of  NAMs in the area of IATAs.  Impact for EFSA and partners :