Dec. 27, 2018  5  US 2018/0373148 Al  -continued  X RA  X RA  0  0  Oy  B,  O  O  O*OR’ OJ~OR’  Br  Br  :(  :(  Br  OR 1  ArOR$^{1 }$ 0~  Br  OAABr  XR’  0  0  ~  Br  MYO*  o  I  #  OR 1  Br  -continued  XR’  0  0  ~  OR 1  MYO~  O  ~lli  Br  XR"  0  0  o  I  Br  #  OR 1  Br  XR’  0  0  }QyoY’  o  I  #  OR 1  Br  ~OR’  f3yR’  ON  O~lli  Br 