fiSCal 2013 TOpiCS N R&D Alliances with Other Companies Astellas Pharma Inc.  _ Annual Report 2014 18 N Continuous Launch of New Products 2013 2014 2013 2014 May P  Launch in Japan of Micamlo Combination Tablets BP for hypertension containing high-dose ingredient Jun. P  Launch in Japan of Acofide for functional dyspepsia treatment Jul. P  Launch in U.K. of XTANDI for prostate cancer treatment Aug. P  Launch in the U.S. of ASTAGRAF XL (extended-release capsules), a new formulation of immunosuppressant Prograf Sep. P  Launch in Europe of VESOMNI, a combination tablet of solifenacin and tamsulosin (generic name) for  treatment of voiding symptoms in protostatic hyperplasia P  Launch in Japan of Bisono Tape, a transdermal anti-hypertensive treatment Jan. P  Launch in Japan of Irribow OD Tablets for diarrhea-predominant irritable bowel syndrome Mar. P  Marketing approval received in Japan for XTANDI for prostate cancer treatment P  Marketing approval received in Japan for Suglat for treatment of type 2 diabetes May P  Agreement on strategic alliance in Japan signed with Amgen Inc. Jun. P  Collaboration agreement signed with Cytokinetics, Inc. in the field of skeletal muscle disease Oct. P  Collaboration agreement signed with Mitokyne, Inc. in the area of mitochondria-related diseases P  Established Astellas Innovation Management to identify and obtain external innovation opportunities Dec. P  Astellas and Immuno-Biological Laboratories Co., Ltd. concluded a co-research agreement regarding  pharmaceutical applications of recombinant human proteins made using transgenic silkworms Jan. P  Formed a strategic alliance with ClearPath Development Company to build vaccine portfolio Mar. P  Entered collaboration agreement with Daiichi Sankyo Company, Limited regarding sharing of  compound libraries —Co-development and co-commercialization of five Amgen pipeline products and establishment of  Amgen Astellas BioPharma K.K. —Invested in respiratory syncytial virus vaccine development $_{R}$ Launched in April 2014 $_{R}$ Launched in May 2014