Transfer Agent for Common Stock in Japan Sumitomo Mitsui Trust Bank, Limited 1-4-1, Marunouchi, Chiyoda-ku, Tokyo 100-8233, Japan Major Shareholders (as of March 31, 2014) Name Shares owned  (Thousand shares) Percentage of total common  shares outstanding The Master Trust Bank of Japan, Ltd. (trust account) 26,422 5.78 State Street Bank and Trust Company 23,302 5.09 Japan Trustee Services Bank, Ltd. (trust account) 20,868 4.56 JP Morgan Chase Bank 385147 13,771 3.01 Nippon Life Insurance Company 13,703 2.99 The Bank of Tokyo-Mitsubishi UFJ, Ltd. 9,881 2.16 The Bank of New York – Jasdec Non-Treaty Account 6,709 1.46 State Street Bank and Trust Company 505225 6,222 1.36 State Street Bank W est Client – Treaty 5,512 1.20 Goldman, Sachs & Co. Reg 5,348 1.17 Notes: Shares owned ar e rounded down to the nearest thousand shares, while the per centage of total common shares outstanding is rounded down to two  decimal places.  The company holds 10,736 thousand shares of treasury stock, but it is not included in the above list of major shareholders. Other companies 3.3% Individuals  and others 7.3% Securities companies 4.4% Financial institutions 29.2% Foreign companies and others 53.4% Treasury stock 2.3% Breakdown of Shareholders (as of March 31, 2014) * Please direct inquiries concerning Annual Report 2014 to: Astellas Pharma Inc. Corporate Communications TEL: +81-3-3244-3202 FAX: +81-3-5201-7473 Issued in September 2014 inancial S ection Annual Report 2014 _  Astellas Pharma Inc.  169$^{F}$