Endorsing the United Nations Global Compact In October 2011, Astellas expressed its support for the United Nations Global Compact (the UN  Global Compact), which consists of ten basic principles related to the four fields of human rights,  labor, the environment and anti-corruption. The UN Global Compact requires its signatories to  make voluntary efforts in realizing the ten principles. Since the signing of the UN Global Compact, we have been further reinforcing our CSR based  management approach to “Contribute toward improving the health of people around the world  through the provision of innovative and reliable pharmaceutical products” to realize our raison d’être. The UN Global Compact’s Ten Principles and Astellas’ Initiatives The UN Global Compact’s Ten Principles Our Initiatives Human RigHts Principle 1 Businesses should support and respect the protection of internationally  proclaimed human rights; and Principle 2 Make sure that they are not complicit in  human rights abuses. • Respect for human rights (P52, P61) • Emphasis on diversity (P60) • Respect for the human rights and personal information of  patients undergoing clinical trials (P55) • Ethical considerations in the use of specimens derived from  humans (P54) • Promotion of CSR procurement (Respect for human rights  and fair employment practices at our business partners) (P57) • Compliance helpline (P73) LaboR Principle 3 Businesses should uphold the freedom  of association and the effective  recognition of the right to collective  bargaining; Principle 4 The elimination of all forms of forced  and compulsory labor; Principle 5 The effective abolition of child labor; and Principle 6 The elimination of discrimination in  respect of employment and occupation. • Provision of opportunities for communication between labor  and management (P61) • Prohibition of forced and compulsory labor (P61) • Promotion of CSR procurement (Management of  occupational health and safety practices and prohibition of  child labor at our business partners) (P57) EnviRonmEnt Principle 7 Businesses should support a  precautionary approach to  environmental challenges; Principle 8 Undertake initiatives to promote greater  environmental responsibility; and Principle 9 Encourage the development and  diffusion of environmentally friendly  technologies. • Reduction of greenhouse gas emissions (P68) • Initiatives for biodiversity (P69) • Initiatives for resource recycling (P69) anti- CoRRuption Principle 10 Businesses should work against  corruption in all its forms, including  extortion and bribery. • Reinforcement of global compliance system (P71) • Anti-bribery/Anti-corruption Initiatives (P72) • Promotion of CSR procurement (Compliance with laws and  promotion of CSR at our business partners) (P57) Source: The UN Global Compact’s ten principles The UN Global Compact asks companies, as responsible members of society, to pursue voluntary activities aimed at building global  frameworks for realizing sustainable growth. As of the end April, 2014, over 10,000 companies and organizations in 145 countries  have declared their agreement with the principles. Astellas Pharma Inc.  _ Annual Report 2014 74 UnITED nATIonS GloBAl comPAcT InITIATIVES