the entire coenzymes Q$_{10 }$when measured under the condi› tion that the reduced coenzyme  Q$_{10 }$ is protected from an  oxidation reaction.  13.  The process according to claim  1,  wherein step (a) or  step (b) is conducted under an inert gas atmosphere.  14.  The process according to claim  13,  wherein the inert  gas atmosphere comprises nitrogen gas.  15.  The process according to claim  1,  wherein the cul› turing is carried out with at least 750 L of culture medium.  16.  The process according to claim  1,  further comprising 10  the step of disrupting the microbial cells.  17.  The process according to claim  1,  wherein the cul› turing is conducted in a culture medium containing a carbon  source, a nitrogen source, a phosphorus source and a micro- nutrient.  *  *  *  *  *  25  US 9,926,580 B2  26 