-continued  H3CO  0  OH  H3CO  0  oyo~  OH  ~  ~  oyo~ 0  <:t•  ~  OH  OH  -continued  ouu  I#  •~COCH;  Br  OH  Cl  Br  0  0 y 0 ~0,J__cH,  OH  ~I  ~  0 ,0  $^{0}$1 0~ 0 ,J__~  ~  I  OH  US 9,217,919 B2  113  114 