20  US 8,852,845 B2  19  -continued  -continued  (Bl-49)  (Bl-50)  S~OH  ¢  CC()  I $_{# }$ o~s~oH  (Bl-51)  9  CC()  I $_{# }$ (Bl-52)  O~OH  CC()  I $_{# }$ ~~  (Bl-53)  OH  CC()  I $_{# }$ O~OH  (Bl-48)  V  ~  I  #  (Bl-46)  OH  CC))  I $_{# }$ (Bl-45)  OH 