U.S. Patent  Feb.28,2017  Sheet 1 of 23  US 9,583,325 B2  Fig. 1  To ESI  -◄- Peristaltic Pump  ◄  -MS/MS  ~  ’O’  Delicate Membrane in  Glass Flow Cell  T Sample  t  Flow  Out  f  In  From  Acceptor  .- Phase  Reservoir  Note: Not To Scale 