143  US 9,360,753 B2  144  -continued  -continued  OX  X  ~  DF3  F~-*CF3 F3C  CF3  F  O  OH  O  OH  X  OX  X  &;, f  V  -;;,  4c,,  0  OH  :)~~~H  OH  OX  XX  <:+,,,  Cf:,, Cf:,,  OH  OH  OH  4cc, 4cc,  ’  ,  o  :,,  OH  ox  OH 