US 2018/0228700 Al  7  Aug. 16, 2018  Example 3  TABLE 4  TABLE 3  [0097]  The data in Table 3 show, for the conditioning  agents A-B and E-Q in the case of use on wet dentin, an  equivalent effect to the conventional phosphoric acid and  adequate adhesion results irrespective of the adhesive. When  the dentin was dried more strongly or even over-dried, the  coefficients of adhesion of the surfaces treated with phos› phoric acid decreased significantly as expected. On the other  hand, the conditioning agents A-G and I tested in this regard  representatively were influenced little or not at all by the  drying process.  $^{1}$Email Preparator blue, Ivoclar Vivadent: 37% phosphoric acid (comparison example)  Shear bond strength values on tooth enamel  (24  h@37°  C.)  30 s Etching  15 s Etching  Solution  Adhesive  time (MPa)  time (MPa)  EP 1  Excite F  29.6 – 4.7  27.2 – 8.8  A  Excite F  25.8  – 2.6  30.7 – 4.6  B  Excite F  24.8  – 5.8  33.5 – 6.1  D  Excite F  29.2 – 4.9  E  Excite F  28.8 – 2.5  F  Excite F  24.1 – 6.3  Shear bond strength values on dentin  (24  h@37°  C.)  Coefficients of adhesion in MPa  (  fracture pattern)  Solution  Adhesive  Wet  Dry  Very dry  EP 1  A  B  C  D  E  F  G  H  K  L  M  N  0  p  Q  EP 1  F  Excite F  28.7 – 2.8 (4/5)  Excite F  31.5  – 5.2 (5/5)  Excite F  28.7  – 5.7 (5/5)  Excite F  Excite F  Excite F  35.8  – 9.2 (5/5)  Excite F  27.5 – 6.1 (5/5)  Excite F  23.9  – 4.4 (5/5)  Excite F  30.6 – 5.4 (5/5)  Excite F  31.0  – 5.6 (5/5)  Excite F  22.2  – 4.4 (5/5)  Excite F  29.6 – 5.1 (5/5)  Excite F  33.6  – 5.8 (5/5)  Excite F  32.5 – 6.7 (5/5)  Excite F  37.9  – 4.1 (5/5)  Excite F  29.2  – 7.3 (5/5)  Excite F  28.5  – 2.0 (5/5)  Excite F  30.7 – 9.3 (5/5)  Prime&  30.7  – 3.5 (5/5)  Bond NT  33.2 – 5.7 (5/5)  34.6  – 5.1 (5/5)  12.9  – 4.8 (0/5)  27.9  – 5.0 (4/5)  25.8  – 8.8 (3/5)  28.8 – 3.1 (5/5)  22.2  – 8.7 (4/5)  31.2  – 6.0 (5/5)  30.4 – 6.9 (3/5)  32.7  – 4.9 (5/5)  29.8  – 4.3 (5/5)  9.90  – 3.4 (0/5)  23.6  – 3.2 (4/5)  25.5  – 4.1 (3/5)  8.3  – 2.2 (0/5)  22.5  – 4.8 (4/5)  27.2  – 13.0 (3/5)  26.7 – 5.8 (4/5)  [0099]  The enamel adhesion values shown in Table 4 are,  irrespective of the tested adhesive, comparable to the con› ventional phosphoric acid for the conditioning agents A-Q  within accuracy of measurements. Even values appearing  lower because of fluctuations in the nature of the tooth  substrate are high enough to ensure a clinically adequate  bond. Because of the hardness of the substrate, enamel  samples always fail adhesively, so that the type of failure  (fracture pattern) was not noted here.  [0098]  The measurement of adhesion to tooth enamel was  carried out analogously to Example 2. Since enamel, as an  almost purely inorganic tissue, contains no collagen fibrils  the drying time was not varied. Therefore, to test the enamel  adhesion, only dry substrate was investigated; after rinsing  off of the etching agent the surface was dried for approx. 5  s with a strong stream of air from a dental unit. The aim was  to obtain the image of a chalky-white enamel surface which  is familiar to a dentist. In order to test the effect of an etching  period reduced to 15 s vis-a-vis the established standard of  30 s, both dwell periods were investigated for selected  samples. The results for the enamel coefficients of adhesion  are given in Table 4.  Determination of Adhesion to Tooth Enamel  [0096]  A continuous layer of the adhesive was applied to  the etched tooth surface by microbrush. Should the tooth  surface no longer glisten wetly after a dwell time of  20s,  a  further layer of adhesive was applied in accordance with the  instructions for use. Aeration then took place with an air  blower until a continuous, glistening film had formed. The  latter was exposed to light with a light-polymerization  device (Bluephase Style; Ivoclar Vivadent) for 10 s. There› after, as described, a composite plug (Tetric EvoCeram  BulkFill; Ivoclar Vivadent) was grafted and the shear bond  strength was measured. The results are summarized in Table  3.  [0095]  Prime i Bond NT:  [0094]  A layer of the adhesive was applied to the etched  tooth surface with a microbrush, massaged in for 10 s with  gentle pressure and then aerated with an air blower until an  immobile film had formed. The latter was exposed to light  with a light-polymerization device (Bluephase Style; Ivoclar  Vivadent) for 10 s. A composite plug (Tetric EvoCeram  BulkFill; Ivoclar Vivadent) was then grafted as described  and the shear bond strength was measured.  [0093]  ExciTE F:  Both adhesives were used on etched tooth surfaces in  accordance with the instructions for use provided by the  manufacturer. 