Tables Table 1: Autocorrelation Estimates for the Dirichlet-Poisson-Binomial (DPB), Dirichlet- Multinomial-Binomial (DMB), and Missing Data algorithms. Table 2: Execution Times for Algorithms. 5 million samples collected. Number of genes k = 6096. Algorithms compared are Dirichlet-Poisson-Binomial (DPB) of Section 4.1, Dirichlet − Multinomial Binomial (DMB) of Section 4.2 and the Missing Data method (MD) described in Section 4.3. DPB MB MD N N N N r N Lag ( α = 1) ( α = 1 /k ) ( α = 1) ( α = 1 /k ) ( α = 1) ( α = 1 /k ) 10 0.905 0.024 0.0001 -0.011 0.606 0.007 20 0.863 0.018 0.020 0.020 0.344 -0.012 40 0.783 -0.029 -0.027 -0.010 0.088 -0.034 80 0.666 0.027 -0.009 -0.018 -0.011 0.011 Method α run time (min.) DPB 1 750 DPB 1/k 730 DMB 1 30 DMB 1/k 50 MD 1 20 MD 1/k 19 28