US 20180230408Al  c19)  United States  c12)  Patent Application Publication  Myntti  c10)  Pub. No.: US 2018/0230408 Al  (43)  Pub. Date:  Aug. 16, 2018  (54)  ANTIMICROBIAL COMPOSITION HAVING  EFFICACY AGAINST ENDOSPORES  (71)  Applicant:  Next Science IP Holdings Pty Ltd,  Sydney, NSW (AU)  (72)  Inventor:  Matthew Franco Myntti,  St.  Augustine, FL (US)  (73)  Assignee:  Next Science IP Holdings Pty Ltd,  Sydney, NSW (AU)  (21)  Appl. No.:  15/751,076  (22)  PCT Filed:  Aug. 5, 2016  (86)  PCT No.:  PCT /USl 6/45905  § 371 (c)(l),  (2) Date:  Feb. 7, 2018  (60)  Provisional application No. 62/202,644, filed on Aug.  7, 2015, provisional application No. 62/212,552, filed  on Aug. 31, 2015.  (52)  U.S. Cl.  CPC ............  CllD 3/38636  (2013.01);  CllD 3/48  (2013.01);  CllD 1183  (2013.01);  CllD 3/0047  (2013.01);  CllD 3/43  (2013.01)  (51)  Int. Cl.  CllD 3/386  CllD 3/48  CllD 3/43  CllD 3/00  CllD 1183  (2006.01)  (2006.01)  (2006.01)  (2006.01)  (2006.01)  Publication Classification  (57)  ABSTRACT  Related U.S. Application Data  A sporicidal composition has a moderately low pH and  includes a glycosidase and the dissocia-tion product of at  least one inorganic oxidizing agent. High effective solute  concentrations can enhance the efficacy of the composition.  The composition can be applied to a surface and allowed to  absorb into an endospore, ultimately killing at least some of  those bacteria in mature endospore form. Surfaces to be  treated include inanimate (hard) surfaces via cleaning and  medical devices such as endoscopes, typically via immer› s10n. 