=- fi  OH  •i:~  *  0~  0  ~~  •  •i:~ •i:~  r-6  O~CN  OH  0  * *  I  otP  OH  F3C  CF3  OH  0  OMe  OH  cx;cM•  0  OMe  ~  I  ~tY  o  ":,  I  OH  *  I  otP  OH  0  •i:~  O~CN  0  ~I  ~  0  #  *  *  I  OH  .  •i:~  0~  OH  0  -continued  -continued  48  US 8,614,033 B2  47 