Vaccine Effectiveness, Burden and Impact Studies (VEBIS) of COVID-19 and Influenza – Tender Specifications OJ/2021/DPR/12924  Clear, detailed, and complete list of all study contacts, description of procedures  used to implement the lot tasks, recommendations for further scientific  development of the content related to the lot.  Task 2: Development of the primary care network  The contractor is expected to develop, a large, multi-country, multi-site study network capable of recruiting a sufficient number of participants for the  analysis. On an annual basis, the contractor is expected to identify and draft a list of sites available and committed for the studies during that year (or  season) and report study sites participating and deliver training for new study sites.  Deliverable (DL)  Description  Estimated  frequency/ Volume  File / form at type  DL 5.2.1. Updated list of  participating  countries/study sites  joining the network  In order to ensure sufficient sample size for stratified analysis (e.g. by virus clade  or by vaccine type/brand), the contractor is expected to develop a large, multi- country, multi-site study network capable of recruiting a sufficient number of  participants for the analysis.  ECDC will support the initial identification of study sites and the contractor will  further assess the feasibility of the study sites to join the study. ECDC aims to  further expand this list and plans to collect interest from the Member States on a  regular basis.  The following aspects shall be considered by the contractor when assessing the  feasibility of study sites to join the study:  • The studies should be performed in at least 10 EU/EEA Member States  and will preferably apply a test-negative case-control design.  • The identified sites shall be able to implement the protocol(s); it is  expected that the contractor will ensure that the sites identify data flows  which will allow capturing information on SARS-CoV variants (such as  whole genome sequencing) and capture the information as part of the  study data collection. Identification of the variants could either be  undertaken at the site/national level in collaboration with the relevant  Once a year, within  12 weeks of signing  specific contract  Word;  Excel 