Oct. 10, 2002  10  US 2002/0147433 Al  5,609,587, and 5,635,191, the disclosure of each of which  has been incorporated herein by reference.  [0081]  Specifically, preferred compositions will have the  following melt profile:  [0082]  By being solid or semisolid at ambient tempera› tures, preferred compositions containing the proton donating  actives do not have a tendency to flow and migrate to a  significant degree to undesired locations of the article to  which they are applied. This means less skin care compo› sition is required for imparting desirable therapeutic, pro› tective and/or conditioning benefits.  [0083]  To enhance immobility of preferred compositions,  the viscosity of the formulated compositions should be as  high as possible to prevent flow within the article to undes› ired location. Unfortunately, in some instances, higher vis› cosities may inhibit transfer of composition to the wearer’s  skin. Therefore, a balance should be achieved so the vis› cosities are high enough to keep the compositions localized  on the surface of the article, but not so high as to impede  transfer to the wearer’s skin. Suitable viscosities for the  compositions will typically range from about 5 to about 500  centipoise, preferably from about 5 to about 300 centipoise,  more preferably from about 5 to about 100 centipoise,  measured at 60°  C. using a rotational viscometer (a suitable  viscometer is available from Lab Line Instrments, Inc. of  Melrose Park,  IL  as Model 4537). The viscometer is oper› ated at 60 rpm using a number 2 spindle.  [0084]  For skin care compositions designed to provide a  therapeutic and/or skin protective benefit in addition to the  benefit derived from the proton donating active(s), a useful  active ingredient in these compositions is one or more skin  protectants or emollients.  As  used herein, the term an  "emollient" is a material that protects against wetness or  irritation, softens, soothes, supples, coats, lubricates, mois› turizes, protects and/or cleanses the skin.  (It will be recog› nized that several of the monographed actives listed above  are "emollients", as that term is used herein.) In a preferred  embodiment, such emollients will have a plastic or a liquid  consistency at ambient temperatures, i.e., about 20-25°  C.  [0085]  Representative emollients useful in the present  invention include, but are not limited to, emollients that are  petroleum-based; sucrose esters of fatty acids; polyethylene  glycol and derivatives thereof; humectants; fatty acid ester  type; alkyl ethoxylate type; fatty acid ester ethoxylates; fatty  alcohol type; polysiloxane type; propylene glycol and  derivatives thereof; glycerin and derivatives thereof, includ› ing glyceride, acetoglycerides, and ethoxylated glycerides of  C$_{12}$-C$_{28 }$ fatty acids; triethylene glycol and derivatives  thereof; spermaceti or other waxes; fatty acids or fatty  alcohol ethers, particularly those having from 12 to 28  carbon atoms in their fatty chain, such as stearic acid and  methyl stearyl ether; propoxylated fatty alcohols; other fatty  esters of polyhydroxy alcohols; lanolin and its derivatives;  kaolin and its derivatives; any of the monographed skin care  agents listed above; or mixtures of these emollients. Suitable  petroleum-based emollients include those hydrocarbons, or  mixtures of hydrocarbons, having chain lengths of from 16  to 32 carbon atoms. Petroleum based hydrocarbons having  these chain lengths include mineral oil (also known as  "liquid petrolatum") and petrolatum (also known as "min› eral wax,""petroleum jelly" and "mineral jelly"). Mineral oil  usually refers to less viscous mixtures of. Petrolatum usually  refers to more viscous mixtures of hydrocarbons. Petrolatum  and mineral oil are particularly preferred emollients for  compositions of the present invention.  [0086]  Suitable fatty acid ester type emollients include  those derived from C$_{12}$-C$_{28 }$ fatty acids, preferably C$_{1}$ cC$_{22 }$ saturated fatty acids, and short chain ( C$_{1 }$-C$_{8}$ ,  preferably  C$_{1 }$-C$_{3}$ )  monohydric alcohols. Representative examples of  such esters include methyl palmitate, methyl stearate, iso› propyl laurate, isopropyl myristate, isopropyl palmitate,  ethylhexyl palmitate and mixtures thereof. Suitable fatty  acid ester emollients can also be derived from esters of  longer chain fatty alcohols (C$_{12}$-C$_{28}$, preferably C$_{12}$-C$_{16}$ )  and shorter chain fatty acids e.g., lactic acid, such as lauryl  lactate and cetyl lactate.  [0087]  Suitable fatty ester type emollients also include  polyolpolyesters as described in U.S. Pat. No. 5,609,587,  issued to Roe on Mar. 11, 1997, the disclosure of which is  incorporated herein by reference.  Exemplary polyols  include, but are not limited to, polyhydric compounds such  as pentaerythritol; sugars such as raffinose, maltodextrose,  galactose, sucrose, glucose, xylose, fructose, maltose, lac› tose, mannose and erythrose; and sugar alcohols such as  erythritol, xylitol, malitol, mannitol and sorbitol. Such poly› ols are esterified with fatty acids and/or other organic  radicals having at least two carbon atoms and up to 30  carbon atoms. While it is not necessary that all of the  hydroxyl groups of the polyol be esterified, preferred poly› olpolyester emollients of the present invention have sub› stantially all ( e.g. at least about 85%) of the hydroxyl groups  esterified. Particularly preferred are sucrose polyolpolyes› ters such as sucrose polycottonate, sucrose polysoyate, and  sucrose polybehenate. Mixtures of such polyolpolyesters are  also suitable emollients for the present invention.  [0088]  Suitable alkyl ethoxylate type emollients include  C -C$_{22 }$fatty alcohol ethoxylates having an average degree  ol’ethoxylation of from about 2 to about 30. Preferably, the  fatty alcohol ethoxylate emollient is selected from the group  consisting of lauryl, cetyl, and stearyl ethoxylates, and  mixtures thereof, having an average degree of ethoxylation  ranging from about 2 to about 23. Representative examples  of such alkyl ethoxylates include laureth-3 ( a lauryl ethoxy› late having an average degree of ethoxylation of 3), laureth- 23 (a lauryl ethoxylate having an average degree of ethoxy› lation of 23), ceteth-10 (a cetyl alcohol ethoxylate having an  average degree of ethoxylation of 10) and steareth-10 (a  stearyl alcohol ethoxylate having an average degree of  ethoxylation of 10). When employed, these alkyl ethoxylate  emollients are typically used in combination with the petro› leum-based emollients, such as petrolatum, at a weight ratio  of alkyl ethoxylate emollient to petroleum-based emollient  of from about 1:1 to about 1:5, preferably from about 1:2 to  about 1:4.  Characteristic  %  liquid at  room temp. (20° C.)  %  liquid at  body temp. (37°  C.)  final melting point  (°  C.)  Preferred Range  2-50  25-95  "’;38  Most Preferred  3-25  30-90 