The bubbles of nothing considered here affect many otherwise stable flux vacua. One should consider this instability as a new decay channel whose end result is a type of terminal vacuum, a vacuum without a classical spacetime. This is clearly relevant for any program undertaking the assigning of probabilities to different vacua in the landscape, the so-called measure problem. (See for example, [23] and references therein.) We would like to thank Jaume Garriga, Oriol Pujolas and Alex Vilenkin for very helpful conversations and discussions. J.J.B.-P. would like to thank the Theory Division at CERN for its hospitality and support in the early stages of this work. J.J.B.-P. is supported in part by the National Science Foundation under grant 06533561. B.S. is supported in part by Foundational Questions Institute grant RFP2-08-26A. VI. ACKNOWLEDGMENTS [1] E. Witten, “Instability Of The Kaluza – Klein Vacuum,” Nucl. Phys. B 195 , 481 (1982). [2] M. R. Douglas and S. Kachru, “Flux compactification,” Rev. Mod. Phys. 79 , 733 (2007). [3] E. Cremmer and J. Scherk, “Spontaneous Compactification Of Space In An Einstein Yang- Mills Higgs Model,” Nucl. Phys. B 108 , 409 (1976). [4] P. G. O. Freund and M. A. Rubin, “Dynamics Of Dimensional Reduction,” Phys. Lett. B 97 , 233 (1980). [5] S. Randjbar-Daemi, A. Salam and J. A. Strathdee, “Spontaneous Compactification In Six- Dimensional Einstein-Maxwell Theory,” Nucl. Phys. B 214 , 491 (1983). [6] M. Gell-Mann and B. Zwiebach, “Space-Time Compactification Due To Scalars,” Phys. Lett. B 141 , 333 (1984). [7] S. B. Giddings, S. Kachru and J. Polchinski, “Hierarchies from fluxes in string compactifica- tions,” Phys. Rev. D 66 , 106006 (2002). [8] S. Kachru, R. Kallosh, A. D. Linde and S. P. Trivedi, “De Sitter vacua in string theory,” Phys. Rev. D 68 , 046005 (2003). [9] R. Bousso and J. Polchinski, “Quantization of four-form fluxes and dynamical neutralization of the cosmological constant,” JHEP 0006 , 006 (2000); L. Susskind, “The anthropic landscape 14