Revised theme paper in light of the comments received from the  European Commission (DG SANTE, JRC), ENVI Agencies, EU Member  States and EFSA’s Scientific Committ ee members in the phases 1 & 2 of  EFSA’s consult ation process  Disclaimer: This document does not present future projects calls as part of EFSA work programme,  or any future position of EFSA. It aims to support the development of a roadmap for action and its  content can be subject to change.  • By 2030, EFSA and partners will be equipped for the routine implementation of human health  risk assessment to multiple chemicals, across EFSA’s domains of activity. Harmonised tools  and consolidated data will be available for a structured and efficient assessment of both  dietary and non-dietary exposure to multiple chemicals. Available methods will be fit-for- purpose and address requirements from the sectoral legislations. • The main objective is to develop and implement a harmonised approach for the assessment  of human health risks resulting from both dietary and non-dietary exposure to multiple  chemicals. The proposed theme will therefore be divided in four work packages: methods  development, tools harmonisation, data consolidation and implementation.  • In a first instance, EFSA will screen the deliverable of previous projects to identify relevant  methodological developments in this area. These methods will then be translated into  practical and harmonised tools that can be applied across all domains of EFSA, and necessary  input data will be consolidated into structured formats. In a second instance, EFSA will  continue to monitor other ongoing projects and identify possible needs for further innovation  and methodological development in both hazard and exposure assessment.  • In order to ensure a steady and manageable progress, risk assessment to multiple chemicals  will be implemented with a stepwise approach. EFSA will first prioritise the routine risk  assessment of dietary exposure to multiple pesticides, with a subsequent integration of non- dietary exposure to pesticides. Methods to prioritise other chemicals will also be developed  and, building on the experience gained in the area of pesticides, the scope of the  implementation plan will be extended to other chemicals.  • In view of increasing the outreach towards national competent authorities, EFSA will promote  the implementation of the methods and tools developed and provide adequate training,  where necessary.  European Food Safety Authority  Via Carlo Magno 1A – 43126 Parma, Italy  Tel. +39 0521 036 111│ www.efsa.europa.eu  Scope and objectives: Vision:  ANNEX 5  Theme (concept) paper on Risk Assessment of  Combined Exposure to Multiple Chemicals  (RACEMiC)