the end of 2020 that would set out priorities for the ongoing work on method development  and the subsequent implementation of the methodology for the assessment of combined  exposure to pesticides.  • A draft roadmap on the assessment of human health risks from combined exposure to  multiple chemicals was already elaborated by EFSA and discussed with Member States under  the umbrella of EFSA’s Advisory Forum. This draft document already provides a solid basis  for the development of a more comprehensive roadmap within the current framework. • A European Partnership for the Assessment of Risk from Chemicals (PARC) 5 and the  additional calls for proposals under the Green Deal 6  priorities in 2020 (e.g. call 8 topic 2  “Fostering regulatory science to address chemical and pharmaceutical mixtures: from  science to evidence- based policies”) is currently under preparatio n with Horizon Europe  aiming to start in 2022 and 2021, respectively. This partnership may be considered for  funding innovative research projects which may support the development of new methods  in the area of multiple chemicals.  • Several national competent organisations have acquired valuable experience in the  development of tools and calculators, specifically designed for the assessment of multiple  chemicals (i.e. RIVM, DTU, ANSES, Finnish Food Authority). Harmonisation efforts were also  undertaken in the framework of the EU-funded project EuroMix, which involved additional  organisations such as BfR, BPI, FERA, HSE, etc. These organisations may be considered by  EFSA to set up a wider partnership specifically dedicated to the elaboration of a collaborative  platform for harmonised tools on multiple chemicals risk assessment.  • EFSA already has a framework contract with Istituto Mario Negri for the enhancement of the  OpenFoodTox Database and EFSA previously cooperated with DTU for the collection of  toxicological data in the area of pesticides. These successful experiences are a solid basis  for EFSA to build another partnership on the consolidation of toxicological data required for  multiple chemicals risk assessment. This partnership could include other Member States  organisations that may be specialised/interested in certain effects or organ systems  • The European Green Deal announces the development of a chemical strategy for  sustainability in 2020, which will require the EU agencies and scientific bodies to move  towards a process of one assessment for one substance (avoiding contradicting assessment  outcomes from the different agencies). ECHA, EMA and EFSA will therefore need to  strengthen their cooperation in view of developing risk assessment approaches that address  combined exposure via multiple routes. The capacity to assess risks for combined dietary  and non-dietary exposure will be the first step towards a more holistic approach addressing  combined exposure to multiple chemicals. Activities of JRC and EEA, which mainly addresses  non-dietary exposure to chemicals, will need to be monitored as well.  • EFSA will cooperate with international partners WHO and OECD to ensure harmonisation  with their assessment frameworks for multiple chemicals. Furthermore, EFSA will explore  possibilities to re-use work from non- EU partners. This includes the US EPA’s Adverse  Outcome Pathways Database (which may serve as a basis for future enhancement of  OpenFoodTox) and Health Canada’s cumulative risk assessment of triazole pesticides  (which  may be of relevance for EFSA’s assessment of cranio -facial malformations scheduled in  $^{5}$https://ec.europa.eu/info/sites/info/files/research_and_innovation/funding/documents/ec_rtd_he-partnerships-chemical-risk- assessment.pdf $^{6}$ https://ec.europa.eu/info/research-and-innovation/strategy/european-green-deal/call_en 3  Cooperation: