US 10,007,180 B2  69  70  -continued  -continued  (Q-21)  ~I  ~  o~o  $_{0 }$/  ~I  ~  o~o  0  0  I  I  (Q-23)  ~I  ~  o~o  0  I  I  I  0  0  OH  (Q-26)  ~I  ~  011)6  0  HO  OH  HO  OH  (Q-25)  ~I  ~  o~o  OH  0  0  I  I  (Q-24)  +H,Q  ~I  ~  o~o  0  0  I  I  I  I  0  0  OH 