a. Engagement of IT experts corresponding to the relevant IT  profiles listed in Annex 11 of the Technical Specifications  and amounting to minimum 2000 person-days.  b. The work related to each referenced contract must have  been performed during a continued period of minimum 6  months, during the timeframe from 23/11/2016 to  08/01/2021  and must have resulted in a major release  deployed to production.  c. Minimum 2 referenced contracts must have been performed  in DevOps mode.  d. Minimum 2 referenced contract must have been performed  with applied cheminformatics techniques for chemical  searching  and  clustering  with  tailor-made,  complex  visualisation such as graphs comprising several thousand  nodes and edges.  e. Minimum 1 referenced contract must have been performed  after/upon takeover of a production grade information  system from a third party(ies) and resulting in a seamless  transitioning of development activities.  4. Minimum volumes for each referenced contract for Information systems takeover:  a. Engagement of IT experts corresponding to the relevant IT  profiles listed in Annex 11 of the Technical Specifications.  b. The work related to each referenced contract must have  been performed during a continued period of maximum 6  months, during the timeframe from 23/11/2016 to  08/01/2021  and must have resulted in the full takeover  of a production grade information systems from a third  party(ies).  c. Systems with over 500 registered users 18 ;  5. Minimum volumes for referenced contract for Information  systems  operations:  a. Each referenced contract must have the engagement of IT  experts corresponding to the relevant IT profiles listed in  Annex 11 of the Technical Specifications and amounting to  minimum 2000 man-days.  b. The work related to referenced contract must have been  performed during a continued period of minimum 2 years,  during the timeframe from  23/11/2016 to 08/01/2021 .  c. Minimum 2 referenced contracts must have been performed  in DevOps mode.  $^{18}$  Registered user relates to a user having access to the system, implemented in frame of the referenced contract,  where the user was identified with a unique identifier and a password, e.g. employees using the developed  system, freelancers working for an institution and using the system as uniquely identified person, extranet users,  etc. Registered user is not someone using the system, e.g. someone browsing a website or a guest in an online  shop cannot be understood in the contract reference as a valid user fulfilling this requirement. 24