US 2019/0287691 Al  58  Sep. 19,2019  !ates into efficacious in vivo europium decorporation,  Dalton Trans. 40 (2011) 8340. doi: 10.1039/cldt10840a.  [0500]  K. L. Nash, The Chemistry of TALSPEAK: A  Review of the Science, Solvent Extr. Ion Exch. 33 (2015)  1-55. doi: 10.1080/07366299.2014.985912.  [0516]  Deri, M. A. et al. p-SCN-Bn-HOPO: A Superior  Bifunctional Chelator for 89Zr ImmunoPET.  Bioconj.  Chem.  26, 2579-2591 (2015).  [0515]  Gorden, A. E. V., Xu, J., Raymond, K. N. &  Durbin, P. Rational Design of Sequestering Agents for  Plutonium and Other Actinides.  Chem. Rev.  103, 4207- 4282 (2003).  [0514]  Abergel, R. J. et al. Biomimetic actinide chelators:  an update on the preclinical development of the orally  active hydroxypyridonate decorporation agents 3,4,3-LI  (1,2-HOPO) and 5-LIO(Me-3,2-HOPO).  Health Phys.  99,  401-407 (2010).  [0499]  L. R. Morss, N. M. Edelstein, J. Fuger, The Chem› istry of the Actinide and Transactinide Elements, 4th ed.,  Springer, 2010.  [0498]  V. Ostapenko, A. Vasiliev, E. Lapshina, S. Ermo› laev, R. Aliev,  Y. Totskiy, B. Zhuikov, S. Kalmykov,  Extraction chromatographic behavior of actinium and  REE on DGA, Ln and TRU resins in nitric acid solutions,  J. Radioanal. Nucl. Chem. 306 (2015) 707-711. doi:10.  1007 /sl 0967-015-4331-y.  [0513]  Cary, S. K. et al. Advancing Understanding of the  +4 Metal Extractant Thenoyltrifluoroacetonate (TTA-);  Synthesis and Structure ofMwTTA$_{4 }$ (Miv=zr,  Hf, Ce, Th,  U, Np, Pu) and  Mm  (TTA)$_{4 }$ (MIII=Ce,  Nd, Sm, Yb).  Inorg.  Chem.  57, 3782-3797 (2018).  [0512]  Horwitz, E. P. & Bloomquist, C. A. A. Chemical  separations for super-heavy element searches in irradiated  uranium targets.  J. Inorg. Nucl. Chem.  37, 425-434  (1975).  [0511]  Zhu, Z.-X., Sasaki, Y., Suzuki, H., Suzuki, S. &  Kimura, T. Cumulative study on solvent extraction of  elements by N,N,N’,N’-tetraoctyl-3-oxapentanediamide  (TODGA) from nitric acid into n-dodecane.  Anal. Chim.  Acta  527, 163-168 (2004).  [0497]  V. Radchenko, J.  W.  Engle, J. J. Wilson, J. R.  Maassen,  F.  M. Nortier, W. A. Taylor, E. R. Birnbaum, L.  A. Hudston, K. D. John, M. E. Fassbender, Application of  ion exchange and extraction chromatography to the sepa› ration of actinium from proton-irradiated thorium metal  for analytical purposes, J. Chromatogr. A. 1380 (2015)  55-63. doi: 10.1016/j.chroma.2014.12.045.  [0496]  C. Wai, D. Fisher, others, Carboxylate-derived cal› ixarenes with high selectivity for actinium-225, Chem.  Commun. (1998) 377-378.  [0495]  D. Lundberg,  I.  Persson, L. Eriksson, P. D’ Angelo,  S. De Panfilis, Structural Study of the N,N’-Dimethylpro› pyleneurea Solvated Lanthanoid(III) Ions in Solution and  Solid State with an Analysis of the Ionic Radii of Lan› thanoid(III) Ions, Inorg. Chem. 49 (2010) 4420-4432.  doi: 10.1021/ic100034q.  [0510]  Leydier, A. et al. Recovery of uranium (VI) from  concentrated phosphoric acid using bifunctional reagents.  Hydrometallurgy 171, 262-266 (2017).  [0509]  Beltrami, D. et al. Recovery of Uranium from Wet  Phosphoric Acid by Solvent Extraction Processes.  Chem.  Rev.  114, 12002-12023 (2014).  [0494]  D. Lundberg,  I.  Persson, The size of actinoid(III)  ions-structural analysis vs. common misinterpretations,  Coard. Chem. Rev. 318 (2016) 131-134. doi: 10.1016/j.  ccr.2016.04.003.  [0493]  A. E. Martell, R. M. Smith, R. J. Motekaitis, NIST  Standard Reference Database 46, (n.d.).  [0508]  Oganessian, Y. T. et al. Experimental studies of the  249 Bk+48 Ca reaction including decay properties and  excitation function for isotopes of element 117, and  discovery of the new isotope 277 Mt.  Phys. Rev.  C 87,  (2013).  [0507]  Roberto, J. B. et al. Actinide targets for the syn› thesis of super-heavy elements.  Nucl. Phys. A  944, 99-116  (2015).  [0492]  G. J.-P. Deblonde, M. Sturzbecher-Hoehne, P. B.  Rupert, D. D. An, M.-C. Illy, C. Y. Ralston, J. Brabec,  W.  A. de Jong, R. K. Strong, R. J. Abergel, Chelation and  stabilization of berkelium in oxidation state+IV,  Nat.  Chem.  (2017). doi: 10.1038/nchem.2759.  [0491]  G. J.-P. Deblonde, M. Sturzbecher-Hoehne, R. J.  Abergel, Solution Thermodynamic Stability of Com› plexes Formed with the Octadentate Hydroxypyridinon› ate Ligand 3,4,3-LI(l,2-HOPO): A Critical Feature for  Efficient Chelation of Lanthanide(IV) and Actinide(IV)  Ions, Inorg. Chem. 52 (2013) 8805-8811. doi: 10.1021/  ic4010246.  [0506]  Veliscek-Carolan, J. Separation of actinides from  spent nuclear fuel: A review.  J. Hazard. Mater.  318,  266-281 (2016).  [0505]  Witze, A. Nuclear power: Desperately seeking plu› tonium. Nature News 515, 484-486 (2014).  [0504]  Hagemann, U. B. et al. In Vitro and In Vivo  Efficacy of a Novel CD33-Targeted Thorium-227 Conju› gate for the Treatment of Acute Myeloid Leukemia.  Mal.  Cancer Therapeutics  15, 2422-2431 (2016).  [0503]  NSAC Isotopes Subcommittee.  Meeting isotope  needs and capturing opportunities for the future: the  2015  long range plan for the DOE-NP isotope program.  1-160  (US DOE, 2015).  [0490]  M. Sturzbecher-Hoehne, T. A. Choi, R. J. Abergel,  Hydroxypyridinonate Complex Stability of Group (IV)  Metals and Tetravalent f-Block Elements: The Key to the  Next Generation of Chelating Agents for Radiopharma› ceuticals, Inorg. Chem. 54 (2015) 3462-3468. doi:  10.1021/acs.inorgchem.5b00033.  [0489]  M. Sturzbecher-Hoehne, B. Kullgren, E. E. Jarvis,  D. D. An, R. J. Abergel, Highly Luminescent and Stable  Hydroxypyridinonate Complexes: A Step Towards New  Curium Decontamination Strategies, Chem.-Eur. J. 20  (2014) 9962-9968. doi: 10.1002/chem.201402103.  [0488]  M. Sturzbecher-Hoehne, P. Yang, A. D’ Alo, R. J.  Abergel, Intramolecular sensitization of americium lumi› nescence in solution: shining light on short-lived forbid› den 5f transitions, Dalton Trans. (2016). doi: 10. 1039/  C$_{6}$DT00328A.  [0502]  J. T. Harvey, Production of Actinium-225 via High  Energy Proton Induced Spallation ofThorium-232. Final  Technical Report DE-SC0003602, NorthStar Medical  Radioisotopes, LLC, n.d. https: I/world wide web.osti.  gov/ scitech/serv lets/purl/ 103 2445/.  [0501]  K. V. Lohithakshan, P. Patil, S. K. Aggarwal,  Solvent extraction studies of plutonium(IV) and americi› um(III) in room temperature ionic liquid (RTIL) by di-2- ethyl hexyl phosphoric acid (HDEHP) as extractant, J.  Radioanal. Nucl. Chem. 301 (2014) 153-157. doi:10.  1007/s 10967-014-3119-9. 