Orvieto , located in Umbria between Rome and Florence , was once the capital of Etruria , an ancient federation of 12 Etruscan towns .
<response> <location>Orvieto</location> , located in <location>Umbria</location> between <location>Rome</location> and <location>Florence</location> , was once the capital of <location>Etruria</location> , an ancient federation of 12 <misc>Etruscan</misc> towns . </response>