Hello doctor,I was diagnosed with chlamydia trachomatis about six weeks ago. After that, I had some discharge and discomfort inside the urethra. They did a PCR test, and the diagnosis was Chlamydia trachomatis. The doctor gave me Azithromycin, I took six pills as a single dose. I still had discharge and discomfort after one week, so I went back. I had a sensitive reaction to Doxycycline before, it gives me strong oral thrush, very painful. So I told the doctor to give me something else. He gave me Levofloxacin 500 mg, once daily for two weeks. I still had discharge after that, although the discomfort was less pronounced. I tried to take Doxycycline, but after taking only one pill, 100 mg of Doxycycline, I immediately developed oral thrush (it was hard to speak and eat for 10 days) and itchy and painful fungus on my penis, so I stopped. Now after two weeks the oral thrush is gone, but I have discharge and discomfort again like in the beginning. What should I do? Is there another antibiotic I can use? Do I have to use Doxycycline and take antifungal medicine like Fluconazole at the same time? Kindly help.
Hi. Yes, if you can tolerate Doxycycline, you may combine it with Fluconazole. Fungal infection may have occurred as a coincidence. So it may not be due to Doxycycline itself. Another option is to try Cynomycin (Minocycline) 100 mg twice daily for 14 days. You may add an anti-inflammatory after consulting your doctor. If there is dysuria or straining in urine, add an alpha blocker like Tamsulosin. Take care. Please use a condom till your infection goes away.  Take care.