My mother has had significant weight loss, (about 5-10%) in 3 months, is nauseated, especially in the morning, and is fatigued. She is 71 years old and has never been sick and has never had depression. She is a non-smoker and a non-drinker. She has a hgb of 162. currently her c-reactive protein is normal. She describes her stools to be dark but not black. She also has a uti, which is being treated. She had an abd ultrasound 2 years ago because of symptoms of lower abd discomfort but they saw nothing.  She is to have a colonoscopy and and gastroscopy as well as another ultra sound and possibly a CT of the abd.
Hello, As per your statement your mother is C/O1) Nausea in the morning2) Loss of weight3) Fatique4) Dark colored motional investigations done - Hub and C-reactive proteins are normal - So we can't expect any major inflammatory disease.USG abdomen done 2 years back was normalize is waiting for gastrostomy and colonoscopy and repeat USG abdomen and possibly a CT abdomen. First you must arrive at a probable diagnosis and then investigation should be as per the probability. You have not mentioned whether she is having DM/HT/HD. Even a UTI can produce all the symptoms you have mentionedProbable Diagnosis. Do a urinalysis - Macro, Micro and culture and sensitivity a motion examination - Macro, Micro, RBC and culture and sensitivity. If RBC is present - it may be GI Bleeder the above you can come to a conclusion - what investigation is needed further.Accordingly, you do the investigation and treat her - instead of subjecting her to the cumbersome unwanted investigation. She will get alright - because I don't expect any major problem. Best wishes