Hello doctor,I have a query on ectopic pregnancy. My wife is having one and her beta hCG levels were 125.25 ml after taking her first shot of Methotrexate. Yesterday, she got her second shot and her beta hCG levels today were 141. I wanted to know how much time Methotrexate takes to low down those levels and I was wondering if we were a little hurried in taking the second dose so quickly.
Hello, Welcome to Chat Doctor forum. I hope you had taken the Methotrexate dose under supervision only. The usual protocol is to check for a repeat beta hCG on the fourth day of taking Methotrexate. Early testing may cause undue anxiety and panic as it takes some time for the levels to come down. Moreover, a few times the levels get slightly elevated after a Methotrexate. So stay calm and follow the instructions of the gynecologist you are following. Just report to the emergency in case of any acute pain, giddiness or bleeding. 