Hello doctor,My wife underwent double marker test. Results are as follows. Please tell me if there is any risk factor regarding the pregnancy. Her age is 31 years. PAPP-A : 0.35 MoM, fb-hCG 2.14 MoM, age risk 1:743, biochemical T21 risk 1:54, combined trisomy 21 risk 1:226, trisomy 13/18 + NT.
Hello, Welcome to Chat Doctor forum. Yes, there is a risk of the baby being born with Down\s syn ChatDoctor.  To confirm it, there is a test called chorionic villus sampling where the sample of the placenta is taken and chromosomal analysis is done to rule out trisomy 21, 18, and 13, that is abnormal chromosome. But there is another blood test which is done at 16 to 18 weeks of pregnancy plus level 2 ultrasound scan to rule out any stigma of trisomy 13, 18, and 21.  To confirm at this stage of pregnancy, amniocentesis is done for chromosomal analysis. If AA tests are suggesting trisomy then I suggest you go for termination of pregnancy. For more information consult an obstetrician and gynecologist online 