hello doc,i am27 year old.i was diagonsed with MTHFR 677- T MUTATION/POLYMORPHISM: (Present TT) after four miscarriage . i am really worried& nervous about this.i live in dubai but here medical is not good. one doctor suggest me you should take extra folic acid, B6, B12 and baby asprin also but i have lost my 4 child here .i can not take a risk of another m/c . i am not trust on that .can you please help me should i take these medicine or not. and which type of treatment i should take during pregnany or before pregnancy.
Hi, You have a predisposition for recurrent abortion it is due to this MTHFR condition and this causes high levels of a protein called homocysteine, which effects your blood vessels. This can have implications for both you and your pregnancy. You are more likely to get a condition called deep vein thrombosis which can lead to even more serious problem called pulmonary embolism.Also, the pregnancy loses are due to this, as blood vessels of the placenta are getting clogged by the protein. You have to consult a Hematologist or a gynecologist with expertise in thrombophilia. They will start you on low molecular weight heparin an injection which has to be taken once fetal heart activity is seen on ultrasound and has to be continued till 3 months after delivery. You will require constant monitoring by the hematologist and gynecologists during pregnancy. Hope this helps. Regards.