Hi, may I answer your health queries right now ?  Please type your query here...dear sir i am 25 years old male and suffering from severe lower back pain from past 3 months..i have x ray and blood test normal but i am hla b27 positive i am v worried wat it could be..need ur help plz assist..
Dear patient You are suffering from ankylosing spondylitis. HLAB27 means human leukocyte antigen b27 which is positive in patients with ankylosing spondylitis. This disease is hereditary and progressive.  It initially involves both sacroiliac joints and lower back then progresses over years to involve whole spine and large joints of body. At the onset you will have lower back pain more in morning with stiffness. Prognosis is not good and at the end there is fusion of all spine joints. Rib cage joints such as costovertebral and Costco Chat Doctor.  This disease can be controlled with medication and physiotherapy. Start tab HY