Hi, I suffer from auto immune aneamia and had suffered PE together with cyroglobin. At present I am steroids and warfarin and azathiopron and folic acid. I suffer lots of side effects of medidcation. Taking warfarin and the interaction of other medication is very stressful. At times I have started to feel very anxious over small issues. Steroids play a great role with side effects.
Hello, Cryoglobulinemia is quite variable on how bad it is. Mostly it doesn't cause anemia but in those who have serious effects from cryoglobulemia on the blood count, then they need to have it treated.  There are a lot of treatments for it and all have side effects. There can be removal of the serum--it grows back rapidly.  There can be chemotherapy/steroids. There can be anti-lymphocyte monoclonal. If it affects clotting, warfarin is well-studied as preventing death. Newer agents are POSSIBLY effective--but haven't been studied as much as warfarin.  Sorry, but I see good reasons for the medications you are on and few other Chat Doctor.  Bone marrow transplant and anti-lymphocyte monoclonal are OTHER treatments. I wouldn't say they are BETTER treatments.  BUT if ones cryoglobulins affect blood count and clotting. Then SOME treatment is really necessary. Hope I have answered your query. Let me know if I can assist you further. Take care 