Hi.  I am taking methotrexate  on holiday very hot weather and have come out in a heat rash all over my legs. Any suggestions to ease the rash? I have reduced my sun exposure and applied cold compresses but I really wanted to get a tan.. Is this not possible. Why my body reacted this way?
Hello. Thank you for writing to photosensitivity is a rare but well known side effect of Oral Methotrexate.Therefore, it is advisable that you must not try getting tanned till the time you are on methotrexate. Apart from restricting further sun exposure I would suggest you to use a broad spectrum sunscreen whenever outdoors. As a treating doctor I would have also suggested you to use a topical moderately potent topical steroid e.g. fluticasone propionate 0.05% Or mometasone furnace 0.1% cream, to be used twice daily, over the rash. Steroids are anti-inflammatory and would help resolve the rash within a few days. Regards