Dear Dr Raj, I am Dr Parija, Prof.& Head. Head & Neck Surgery at the Regional Cancer Center, at Cuttack. Orissa. I have a relation who is suffering from Myelitis since 3 months (can send u the MRI plates ) with TB Enchephalitis. On Anti. TB drugs. Have taken Immunoglobulin 20 mg/Kg at HIMHANS, Bangalore. Need to consult fr further line of treatment & an appointment. E-mail: YYYY@YYYY Mob: 0000
High dose methylprednisolone is usually the initial treatment of acute transverse myelitis, (although only Class IV evidence supports this practice, which constitutes "insufficient evidence"). Similarly, "insufficient evidence" supports mitoxantrone. Plasma exchange is "possibly" useful based on 1 Class II study, and rituximab "possibly" effective based on 2 Class III studies. "Insufficient evidence" supports azathioprine, cyclophosphamide, and IVG to alleviate symptoms or prevent future attacks.