I started Sinemet today for Parkinson s Disease 1/2 tab 3x s per day. I have my last dose at 8 pm, 1/2 hr. from now. I ve been reading side effects horror stories, & have been med free for the last 2 yrs., as long as I know I have P.D.. Is it ok to skip the last dose occasionally? Thank You
I read your question carefully, and I understand your concern regarding side effects. It would have been useful if you had mentioned also the tablet dosage, there are different Sine met tablets with different concentration of its components, so hard to judge how high a dose is what you have been prescribed. Sine met is not a curing Chat Doctor.  So not taking it won't have any effect on disease progression, it is safe. You won't have the desired effect though. Also skipping it doesn't mean you won't have side effects after the other two dosages (if you have any side effects at all). So I wouldn't skip this dose, only if you experience side effects can you lower the dose, but not by skipping one dose but by taking say 1/4 tablet 3 times daily. I hope to have been of help.