def me_check(pr, fa, ma, ref_count=False):
    """
    Simplest possible way to check ME
    -1 for skipped sites ('.' or hom-ref in all samples
    0 for consistent
    1 for inconsistent
    """
    pr = pr.split(':')[0].split('/')
    fa = fa.split(':')[0].split('/')
    ma = ma.split(':')[0].split('/')
    if '.' in pr + fa + ma:
        return -1
    null = ["0", "0"]
    if not ref_count and pr == null and fa == null and ma == null:
        return -1
    if pr[0] in fa and pr[1] in ma:
        return 0
    if pr[1] in fa and pr[0] in ma:
        return 0
    return 1