Smooth surfaces with non-simply-connected complements
  We give two constructions of surfaces in simply-connected 4-manifolds with non simply-connected complements. One is an iteration of the twisted rim surgery introduced by the first author. We also construct, for any group G satisfying some simple conditions, a simply-connected symplectic manifold containing a symplectic surface whose complement has fundamental group G. In each case, we produce infinitely many smoothly inequivalent surfaces that are equivalent up to smooth s-cobordism and hence are topologically equivalent for good groups. 
Hee Jung Kim, Daniel Ruberman