ESA White paper: Atmospheric modeling: Setting Biomarkers in context
  Motivation: ESAs goal to detect biomarkers in Earth-like exoplanets in the Habitable Zone requires theoretical groundwork that needs to be done to model the influence of different parameters on the detectable biomarkers.   We need to model a wide parameter space (chemical composition, pressure, evolution, interior structure and outgassing, clouds) to generate a grid of models that inform our detection strategy as well as can help characterize the spectra of the small rocky planets detected. 
L. Kaltenegger, F. Selsis