Massive stars in the nuclei and arms of spirals
  Many of the properties of massive stars in external galaxies, such as chemical compositions, mass functions, and ionizing fluxes, can be derived from the study of the associated clouds of ionized gas. Moreover, the signatures of Wolf-Rayet stars are often detected in the spectra of extragalactic H II regions. This paper reviews some aspects of the recent work on the massive star content of nearby spiral galaxies, as inferred from the analysis of giant H II regions. Particular attention is given to regions of high metallicity, including nuclear hot spots, and to the chemical abundance comparison between supergiant stars and ionized gas. 
Fabio Bresolin (Institute for Astronomy, University of Hawai'i)