The dbar steepest descent method for orthogonal polynomials on the real   line with varying weights
  We obtain Plancherel-Rotach type asymptotics valid in all regions of the complex plane for orthogonal polynomials with varying weights of the form $e^{-NV(x)}$ on the real line, assuming that $V$ has only two Lipschitz continuous derivatives and that the corresponding equilibrium measure has typical support properties. As an application we extend the universality class for bulk and edge asymptotics of eigenvalue statistics in unitary invariant Hermitian random matrix theory. Our methodology involves developing a new technique of asymptotic analysis for matrix Riemann-Hilbert problems with nonanalytic jump matrices suitable for analyzing such problems even near transition points where the solution changes from oscillatory to exponential behavior. 
K. T.-R. McLaughlin and P. D. Miller