"Voici ce que j'ai trouve": Sophie Germain's grand plan to prove   Fermat's Last Theorem
  A study of Sophie Germain's extensive manuscripts on Fermat's Last Theorem calls for a reassessment of her work in number theory. There is much in these manuscripts beyond the single theorem for Case 1 for which she is known from a published footnote by Legendre. Germain had a fully-fledged, highly developed, sophisticated plan of attack on Fermat's Last Theorem. The supporting algorithms she invented for this plan are based on ideas and results discovered independently only much later by others, and her methods are quite different from any of Legendre's. In addition to her program for proving Fermat's Last Theorem in its entirety, Germain also made major efforts at proofs for particular families of exponents. The isolation Germain worked in, due in substantial part to her difficult position as a woman, was perhaps sufficient that much of this extensive and impressive work may never have been studied and understood by anyone. 
Reinhard Laubenbacher and David Pengelley