Driven translocation of a polymer: fluctuations at work
  The impact of thermal fluctuations on the translocation dynamics of a polymer chain driven through a narrow pore has been investigated theoretically and by means of extensive Molecular-Dynamics (MD) simulation. The theoretical consideration is based on the so-called velocity Langevin (V-Langevin) equation which determines the progress of the translocation in terms of the number of polymer segments, $s(t)$, that have passed through the pore at time $t$ due to a driving force $f$. The formalism is based only on the assumption that, due to thermal fluctuations, the translocation velocity $v=\dot{s}(t)$ is a Gaussian random process as suggested by our MD data. With this in mind we have derived the corresponding Fokker-Planck equation (FPE) which has a nonlinear drift term and diffusion term with a {\em time-dependent} diffusion coefficient $D(t)$. Our MD simulation reveals that the driven translocation process follows a {\em super}diffusive law with a running diffusion coefficient $D(t) \propto t^{\gamma}$ where $\gamma < 1$. This finding is then used in the numerical solution of the FPE which yields an important result: for comparatively small driving forces fluctuations facilitate the translocation dynamics. As a consequence, the exponent $\alpha$ which describes the scaling of the mean translocation time $<\tau>$ with the length $N$ of the polymer, $<\tau> \propto N^{\alpha}$ is found to diminish. Thus, taking thermal fluctuations into account, one can explain the systematic discrepancy between theoretically predicted duration of a driven translocation process, considered usually as a deterministic event, and measurements in computer simulations. In the non-driven case, $f=0$, the translocation is slightly subdiffusive and can be treated within the framework of fractional Brownian motion (fBm). 
J. L. A. Dubbeldam, V. G. Rostiashvili, A. Milchev, T. A. Vilgis
cond-mat.soft