Modified likelihood ratio tests in heteroskedastic multivariate   regression models with measurement error
  In this paper, we develop modified versions of the likelihood ratio test for multivariate heteroskedastic errors-in-variables regression models. The error terms are allowed to follow a multivariate distribution in the elliptical class of distributions, which has the normal distribution as a special case. We derive the Skovgaard adjusted likelihood ratio statistics, which follow a chi-squared distribution with a high degree of accuracy. We conduct a simulation study and show that the proposed tests display superior finite sample behavior as compared to the standard likelihood ratio test. We illustrate the usefulness of our results in applied settings using a data set from the WHO MONICA Projection cardiovascular disease. 
Tatiane F. N. Melo, Silvia L. P. Ferrari and Alexandre G. Patriota
math.ST stat.TH