Small Open Chemical Systems Theory and Its Implications to Darwinian   Evolutionary Dynamics, Complex Self-Organization and Beyond
  The study of biological cells in terms of mesoscopic, nonequilibrium, nonlinear, stochastic dynamics of open chemical systems provides a paradigm for other complex, self-organizing systems with ultra-fast stochastic fluctuations, short-time deterministic nonlinear dynamics, and long-time evolutionary behavior with exponentially distributed rare events, discrete jumps among punctuated equilibria, and catastrophe. 
Hong Qian
physics.chem-ph cond-mat.stat-mech q-bio.CB q-bio.PE