Rare coding SNP in DZIP1 gene associated with late-onset sporadic   Parkinson's disease
  We present the first application of the hypothesis-rich mathematical theory to genome-wide association data. The Hamza et al. late-onset sporadic Parkinson's disease genome-wide association study dataset was analyzed. We found a rare, coding, non-synonymous SNP variant in the gene DZIP1 that confers increased susceptibility to Parkinson's disease. The association of DZIP1 with Parkinson's disease is consistent with a Parkinson's disease stem-cell ageing theory. 
A. X. C. N. Valente, J. H. Shin, A. Sarkar, Y. Gao
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