Vessel Segmentation in Medical Imaging Using a Tight-Frame Based   Algorithm
  Tight-frame, a generalization of orthogonal wavelets, has been used successfully in various problems in image processing, including inpainting, impulse noise removal, super-resolution image restoration, etc. Segmentation is the process of identifying object outlines within images. There are quite a few efficient algorithms for segmentation that depend on the variational approach and the partial differential equation (PDE) modeling.   In this paper, we propose to apply the tight-frame approach to automatically identify tube-like structures such as blood vessels in Magnetic Resonance Angiography (MRA) images. Our method iteratively refines a region that encloses the possible boundary or surface of the vessels. In each iteration, we apply the tight-frame algorithm to denoise and smooth the possible boundary and sharpen the region. We prove the convergence of our algorithm. Numerical experiments on real 2D/3D MRA images demonstrate that our method is very efficient with convergence usually within a few iterations, and it outperforms existing PDE and variational methods as it can extract more tubular objects and fine details in the images. 
Xiaohao Cai, Raymond Chan, Serena Morigi, Fiorella Sgallari
math.NA cs.CV