Estimating entanglement of unknown states
  The experimental determination of entanglement is a major goal in the quantum information field. In general the knowledge of the state is required in order to quantify its entanglement. Here we express a lower bound to the robustness of entanglement of a state based only on the measurement of the energy observable and on the calculation of a separability energy. This allows the estimation of entanglement dismissing the knowledge of the state in question. 
Daniel Cavalcanti and Marcelo O. Terra Cunha