On the cosmological constant in quantum cosmology
  Quantization of a dust-like closed isotropic cosmological model with a cosmological constant is realized by the method of B. DeWitt \cite{1}. It is shown that such quantization leads to interesting results, in particular, to a finite lifetime of the system, and appearance of the Universe in our world as penetration via the barrier. These purely quantum effects appear when $\Lambda>0$. 
M.I. Kalinin and V.N. Melnikov