Toward 1% Photometry: End-to-end Calibration of Astronomical Telescopes   and Detectors
  We review the systematic uncertainties that have plagued attempts to obtain high precision and high accuracy from ground-based photometric measurements using CCDs. We identify two main challenges in breaking through the 1% precision barrier: 1) fully characterizing atmospheric transmission, along the instrument's line of sight, and 2) properly identifying, measuring and removing instrumental artifacts. We discuss approximations and limitations inherent in the present methodology, and we estimate their contributions to systematic photometric uncertainties. We propose an alternative conceptual scheme for the relative calibration of astronomical apparatus: the availability of calibrated detectors whose relative spectral sensitivity is known to better than one part in $10^3$ opens up the possibility of in situ relative throughput measurements, normalized to a precision calibrated detector, using a stable but uncalibrated narrowband light source. An implementation scheme is outlined, which exploits the availability of tunable lasers to map out the relative wavelength response of an imaging system, using a flatfield screen and a calibrated reference photodiode. The merits and limitations of this scheme are discussed. In tandem with careful measurements of atmospheric transmission, this approach could potentially lead to reliable ground-based photometry with fractional uncertainties below the percent level. 
Christopher W. Stubbs and John L. Tonry