Sequential change-point detection when unknown parameters are present in   the pre-change distribution
  In the sequential change-point detection literature, most research specifies a required frequency of false alarms at a given pre-change distribution $f_{\theta}$ and tries to minimize the detection delay for every possible post-change distribution $g_{\lambda}$. In this paper, motivated by a number of practical examples, we first consider the reverse question by specifying a required detection delay at a given post-change distribution and trying to minimize the frequency of false alarms for every possible pre-change distribution $f_{\theta}$. We present asymptotically optimal procedures for one-parameter exponential families. Next, we develop a general theory for change-point problems when both the pre-change distribution $f_{\theta}$ and the post-change distribution $g_{\lambda}$ involve unknown parameters. We also apply our approach to the special case of detecting shifts in the mean of independent normal observations. 
Yajun Mei