Experimental Designs for Binary Data in Switching Measurements on   Superconducting Josephson Junctions
  We study the optimal design of switching measurements of small Josephson junction circuits which operate in the macroscopic quantum tunnelling regime. Starting from the D-optimality criterion we derive the optimal design for the estimation of the unknown parameters of the underlying Gumbel type distribution. As a practical method for the measurements, we propose a sequential design that combines heuristic search for initial estimates and maximum likelihood estimation. The presented design has immediate applications in the area of superconducting electronics implying faster data acquisition. The presented experimental results confirm the usefulness of the method. KEY WORDS: optimal design, D-optimality, logistic regression, complementary log-log link, quantum physics, escape measurements 
Juha Karvanen, Juha J. Vartiainen, Andrey Timofeev and Jukka Pekola