Prediction of heart rate response to conclusion of spontaneous breathing   trial by fluctuation dissipation theory
  The non-equilibrium fluctuation dissipation theorem is applied to predict how critically ill patients respond to treatment, based upon data currently collected by standard hospital monitoring devices. This framework is demonstrated on a common procedure in critical care: the spontaneous breathing trial. It is shown that the responses of groups of similar patients to the spontaneous breathing trial can be predicted by the non-equilibrium fluctuation dissipation approach. This mathematical framework, when fully formed and applied to other clinical interventions, may serve as part of the basis for personalized critical care. 
Man Chen, Liang Ren Niestemski, Robert Prevost, Michael McRae, Sharath   Cholleti, Gabriel Najarro, Timothy G. Buchman, and ...
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