CRISPR/Cas9 For Photoactivated Localization Microscopy (PALM)
  We demonstrate that endonuclease deficient Clustered Regularly Interspaced Short Palindromic Repeats CRISPR-associated Cas9 protein (dCas9) fused to the photo-convertible fluorescence protein monomeric mEos3.1 (dCas9-mEos3) can be used to resolve sub-diffraction limited features of repetitive gene elements, thus providing a new route to investigate high-order chromatin organization at these sites. 
Yina Zhu, Pingchuan Li, Paolo Beuzer, Zhisong Tong, Robin Watters, Dan   Lv, Cornelis Murre, and Hu Cang
q-bio.SC q-bio.GN