Giant Negative Mobility of Janus Particles in a Corrugated Channel
  We numerically simulate the transport of elliptic Janus particles along narrow two-dimensional channels with reflecting walls. The self-propulsion velocity of the particle is oriented along either their major (prolate) or minor axis (oblate). In smooth channels, we observe long diffusion transients: ballistic for prolate particles and zero-diffusion for oblate particles. Placed in a rough channel, prolate particles tend to drift against an applied drive by tumbling over the wall protrusions; for appropriate aspect ratios, the modulus of their negative mobility grows exceedingly large (giant negative mobility). This suggests that a small external drive suffices to efficiently direct self-propulsion of rod-like Janus particles in rough channels. 
Pulak K. Ghosh, Peter Hanggi, Fabio Marchesoni, and Franco Nori
physics.bio-ph cond-mat.soft