Modeling the emergence of polarity patterns for the intercellular   transport of auxin in plants
  The hormone auxin is actively transported throughout plants via protein machineries including the dedicated transporter known as PIN. The associated transport is ordered with nearby cells driving auxin flux in similar directions. Here we provide a model of both the auxin transport and of the dynamics of cellular polarisation based on flux sensing. Our main findings are: (i) spontaneous intracellular PIN polarisation arises if PIN recycling dynamics are sufficiently non-linear, (ii) there is no need for an auxin concentration gradient, and (iii) ordered multi-cellular patterns of PIN polarisation are favored by molecular noise. 
Silvia Grigolon, Peter Sollich, Olivier C. Martin
q-bio.TO cond-mat.stat-mech