Knots, Links, and 4-Manifolds
  In this paper we investigate the relationship between isotopy classes of knots and links in S^3 and the diffeomorphism types of homeomorphic smooth 4-manifolds. As a corollary of this initial investigation, we begin to uncover the surprisingly rich structure of diffeomorphism types of manifolds homeomorphic to the K3 surface. 
Ronald Fintushel, Ronald J. Stern