The Impact of the CMB on Large-Scale Structure
  The COBE detection of microwave anisotropies provides the best way of fixing the amplitude of cosmological fluctuations on the largest scales. We discuss the impact of this new, precise normalization and give fitting formulae for the horizon-crossing amplitude as a function of \Omega_0 and n for both open and flat cosmologies. We also discuss the relevant normalization (\sigma_8) at galaxy-clustering scales. Already it is clear that the inferred \sigma_8 can be unnaccepatably high for some of the simplest inflationary models, although many minor variants give an adequate fit. Generic topological defect models appear to fare rather badly, and it is unclear whether minor variants or improved calculations will help much. The detection and mapping of structure in the CMB anisotropy spectrum on smaller scales in the near future will enable us to achieve much stronger constraints on models. 
Martin White and Douglas Scott