Nuclear isotope thermometry
  We discuss different aspects which could influence temperatures deduced from experimental isotopic yields in the multifragmentation process. It is shown that fluctuations due to the finite size of the system and distortions due to the decay of hot primary fragments conspire to blur the temperature determination in multifragmentation reactions. These facts suggest that caloric curves obtained through isotope thermometers, which were taken as evidence for a first-order phase transition in nuclear matter, should be investigated very carefully. 
S.R. Souza, W.P. Tan, R. Donangelo, C.K. Gelbke, W.G. Lynch, M.B.   Tsang