A Natural Renormalization of the One-Loop Effective Action for Scalar   Field in Curved Space-time
  It has been shown that the negative norm states necessarily appear in a covariant quantization of the free minimally coupled scalar field in de Sitter space [1,2]. In this process ultraviolet and infrared divergences have been automatically eliminated [3]. A natural renormalization of the one-loop interacting quantum field in Minkowski space-time ($\lambda\phi^4$ theory) has been achieved through the consideration of the negative norm states [4]. One-loop effective action for scalar field in a general curved space-time has been calculated by this method and a natural renormalization procedure in the one-loop approximation has been established. 
Mohammad Vahid Takook