From CKM Matrix to MNS Matrix: A Model Based on Supersymmetric $SO(10)   \times U(2)_{F}$ Symmetry
  We construct a realistic model based on SUSY SO(10) with U(2) flavor symmetry. In contrast to the commonly used effective operator approach, $126-$dimensional Higgses are used to construct the Yukawa sector. R-parity symmetry is thus preserved at low energies. The Dirac and right-handed Majorana mass matrices in our model have very small mixing, and they combine with the seesaw mechanism resulting in a large leptonic mixing. The symmetric mass textures arising from the left-right symmetry breaking chain of SO(10) give rise to very good predictions; 15 masses (including 3 right-handed Majorana neutrino masses) and 6 mixing angles are predicted by 11 parameters. Both the vacuum oscillation and LOW solutions are favored for the solar neutrino problem. 
Mu-Chun Chen and K.T. Mahanthappa