Stabilization/destabilization of cell membranes by multivalent ions:   Implications for membrane fusion and division
  We propose a mechanism for the stabilization/destabilization of cell membranes by multivalent ions with an emphasis on its implications for the division and fusion of cells. We find that multivalent cations preferentially adsorbed onto a membrane dramatically changes the membrane stability. They not only reduce the surface charge density of the membrane but also induce a repulsive barrier to pore growth. While both of these effects lead to enhanced membrane stability against vesiculation and pore growth, the repulsive barrier arises from correlated fluctuations of the adsorbed cations and favors closure of a pore. Finally, the addition of a small amount of multivalent anions can reverse the membrane stabilization, providing an effective way to regulate membrane stability. 
Bae-Yeun Ha (SFU)