Formation of nematic liquid crystalline phase of F-actin varies from   continuous to biphasic transition
  We show that the isotropic to nematic liquid crystalline phase transition of F-actin can be either continuous or discontinuous, depending critically on the filament length. For F-actin with average filament length > 3 um, we confirm that the transition is continuous in both filament alignment and local concentration. In contrast, for filament length < 2 um the F-actin solution undergoes a first order transition. Tactoidal droplets of co-existing isotropic and nematic domains were observed. Phenomena of nucleation-and-growth and spinodal decomposition both occur, depending sensitively on the exact concentration and average filament length of F-actin. In the late stage, the tactoidal droplets continually grow and occasionally coalesce to form larger granules. 
Jorge Viamontes and Jay X. Tang