A Statistically Robust 3-Sigma Detection of Non-Gaussianity in the WMAP   Data Using Hot and Cold Spots
  We present a careful frequentist analysis of one- and two-point statistics of the hot and cold spots in the cosmic microwave background (CMB) data obtained by the Wilkinson Microwave Anisotropy Probe (WMAP). Our main result is the detection of a new anomaly at the 3-sigma level using temperature-weighted extrema correlation functions. We obtain this result using a simple hypothesis test which reduces the maximum risk of a false detection to the same level as the claimed significance of the test. We further present a detailed study of the robustness of our earlier claim (Larson and Wandelt 2004) under variations in the noise model and in the resolution of the map. Free software which implements our test is available online. 
David L. Larson and Benjamin D. Wandelt (UIUC)