Purity estimation with separable measurements
  Given a large number N of copies of a qubit state of which we wish to estimate its purity, we prove that separable-measurement protocols can be as efficient as the optimal joint-measurement one if classical communication is used. This shows that the optimal estimation of the entanglement of a two-qubit state can also be achieved asymptotically with fully separable measurements. Thus, quantum memories provide no advantage in this situation. The relationship between our global Bayesian approach and the quantum Cramer-Rao bound is discussed. 
E. Bagan, M. A. Ballester, R. Munoz-Tapia and O. Romero-Isart