Dynamical model based on finite stacking enthalpies for homogeneous and   inhomogeneous DNA thermal denaturation
  We present a nonlinear dynamical model for DNA thermal denaturation, which is based on the finite stacking enthalpies used in thermodynamical nearest-neighbour calculations. Within this model, the finiteness of stacking enthalpies is shown to be responsible for the sharpness of calculated melting curves. Transfer-integral and molecular dynamics calculations are performed to demonstrate that the proposed model leads to good agreement with known experimental results for both homogeneous and inhomogeneous DNA. 
Marc Joyeux, Sahin Buyukdagli