Johnson-Kendall-Roberts theory applied to living cells
  Johnson-Kendall-Roberts (JKR) theory is an accurate model for strong adhesion energies of soft slightly deformable material. Little is known about the validity of this theory on complex systems such as living cells. We have addressed this problem using a depletion controlled cell adhesion and measured the force necessary to separate the cells with a micropipette technique. We show that the cytoskeleton can provide the cells with a 3D structure that is sufficiently elastic and has a sufficiently low deformability for JKR theory to be valid. When the cytoskeleton is disrupted, JKR theory is no longer applicable. 
Yeh-Shiu Chu (CDC), Sylvie Dufour (CDC), Jean Paul Thiery (CDC), Eric   Perez (LPS), Fr\'ed\'eric Pincet (LPS)