Uni-directional polymerization leading to homochirality in the RNA world
  The differences between uni-directional and bi-directional polymerization are considered. The uni-directional case is discussed in the framework of the RNA world. Similar to earlier models of this type, where polymerization was assumed to proceed in a bi-directional fashion (presumed to be relevant to peptide nucleic acids), left-handed and right-handed monomers are produced via an autocatalysis from an achiral substrate. The details of the bifurcation from a racemic solution to a homochiral state of either handedness is shown to be remarkably independent of whether the polymerization in uni-directional or bi-directional. Slightly larger differences are seen when dissociation is allowed and the dissociation fragments are being recycled into the achiral substrate. 
M. Nilsson, A. Brandenburg, A.C. Andersen, S. Hoefner