Photothermal heterodyne imaging of individual non-fluorescent   nano-objects
  We introduce a new, highly sensitive, and simple heterodyne optical method for imaging individual non-fluorescent nano-objects. A two orders of magnitude improvement of the signal is achieved compared to previous methods. This allows for the unprecedented detection of individual small absorptive objects such as metallic clusters (of 67 atoms) or non-luminescent semiconductor nanocrystals. The measured signals are in agreement with a calculation based on the scattering field theory from a photothermal-induced modulated index of refraction profile around the nanoparticle. 
Stephane Berciaud (CPMOH), Laurent Cognet (CPMOH), Gerhard Blab   (CPMOH), Brahim Lounis (CPMOH)