Bubble generation in a twisted and bent DNA-like model
  The DNA molecule is modeled by a parabola embedded chain with long-range interactions between twisted base pair dipoles. A mechanism for bubble generation is presented and investigated in two different configurations. Using random normally distributed initial conditions to simulate thermal fluctuations, a relationship between bubble generation, twist and curvature is established. An analytical approach supports the numerical results. 
Peter V. Larsen, Peter L. Christiansen, Ole Bang, Juan F.R. Archilla   and Yuri B. Gaididei