Possible Limits on Photon Propagation from Quantum Gravity and   Space-time Foam
  Many quantum gravity theories imply that the vacuum is filled with virtual black holes. This paper explores the process in which high energy photons interact with virtual black holes and decay into gravitons and photons of lower energy. The effect requires violation (or modification) of Lorentz invariance and implies that high energy photons cannot propagate over arbitrarily large distances. For the standard Planck mass and the likely form for the interaction cross section, this quantum foam limit becomes $\dist < 450$ Mpc $(\egam/10^7 {\rm GeV})^{-5}$. For quantum gravity theories that posit a lower Planck scale, the interaction rate is larger and the limit is stronger. This paper uses extant observations of gamma rays from cosmological sources to constrain this process for varying values of the Planck mass and a range of forms for the interaction cross sections. 
Manasse Mbonye and Fred C. Adams