Metal-to-insulator crossover and pseudogap in single-layer compound   Bi$_{2+x}$Sr$_{2-x}$Cu$_{1+y}$O$_{6+\delta}$ single crystals in high magnetic   fields
  The in-plane $\rho_{ab}(H)$ and the out-of-plane $\rho_c(H)$ magneto-transport in magnetic fields up to 28 T has been investigated in a series of high quality, single crystal, hole-doped La-free Bi2201 cuprates for a wide doping range and over a wide range of temperatures down to 40 mK. With decreasing hole concentration going from the overdoped (p=0.2) to the underdoped (p=0.12) regimes, a crossover from a metallic to and insulating behavior of $\rho_{ab}(T)$ is observed in the low temperature normal state, resulting in a disorder induced metal insulator transition. In the zero temperature limit, the normal state ratio $\rho_c(H)/\rho_{ab}(H)$ of the heavily underdoped samples in pure Bi2201 shows an anisotropic 3D behavior, in striking contrast with that observed in La-doped Bi2201 and LSCO systems. Our data strongly support that that the negative out-of-plane magnetoresistance is largely governed by interlayer conduction of quasiparticles in the superconducting state, accompanied by a small contribution of normal state transport associated with the field dependent pseudogap. Both in the optimal and overdoped regimes, the semiconducting behavior of $\rho_c(H)$ persists even for magnetic fields above the pseudogap closing field $H_{pg}$. The method suggested by Shibauchi \textit{et al.} (Phys. Rev. Lett. \textbf{86}, 5763, (2001)) for evaluating $H_{pg}$ is unsuccessful for both under- and overdoped Bi2201 samples. Our findings suggest that the normal state pseudogap is not always a precursor of superconductivity. 
S. I. Vedeneev and D. K. Maude