Quantum probe for molecular synthesis at room temperature
  In the present study, a prototypical reaction in biochemistry involving a well-known bio-molecule called imidazole (C3H4N2) and its known affinity towards transition metals (such as Co, Ni, Cu, Fe, etc.) has been used to illustrate and exemplify the use of ballistic conductors as probes for molecular reactions at the quantum level. Atomic point contacts of transition metal Co were made using electro-deposition, followed by their reaction with imidazole in an aqueous solution. As the imidazole molecules covalently bond with the Co atoms, the quantized conductance of the nanocontact decreases, thus providing a quantum probe for studying molecular reactions. During the course of the reaction, different conductance channels within the nanocontact become unavailable due to covalent bonding of Co with imidazole, thereby also providing a means of studying the number of channels contributing to the total conductance in the nanocontact itself. 
Susan Z. Hua and Harsh Deep Chopra