A Physarum-Inspired Approach to Optimal Supply Chain Network Design at   Minimum Total Cost with Demand Satisfaction
  A supply chain is a system which moves products from a supplier to customers. The supply chains are ubiquitous. They play a key role in all economic activities. Inspired by biological principles of nutrients' distribution in protoplasmic networks of slime mould Physarum polycephalum we propose a novel algorithm for a supply chain design. The algorithm handles the supply networks where capacity investments and product flows are variables. The networks are constrained by a need to satisfy product demands. Two features of the slime mould are adopted in our algorithm. The first is the continuity of a flux during the iterative process, which is used in real-time update of the costs associated with the supply links. The second feature is adaptivity. The supply chain can converge to an equilibrium state when costs are changed. Practicality and flexibility of our algorithm is illustrated on numerical examples. 
Xiaoge Zhang, Andrew Adamatzky, Xin-She Yang, Hai Yang, Sankaran   Mahadevan, Yong Deng
cs.NE