A semiparametric two-sample hypothesis testing problem for random dot   product graphs
  Two-sample hypothesis testing for random graphs arises naturally in neuroscience, social networks, and machine learning. In this paper, we consider a semiparametric problem of two-sample hypothesis testing for a class of latent position random graphs. We formulate a notion of consistency in this context and propose a valid test for the hypothesis that two finite-dimensional random dot product graphs on a common vertex set have the same generating latent positions or have generating latent positions that are scaled or diagonal transformations of one another. Our test statistic is a function of a spectral decomposition of the adjacency matrix for each graph and our test procedure is consistent across a broad range of alternatives. We apply our test procedure to real biological data: in a test-retest data set of neural connectome graphs, we are able to distinguish between scans from different subjects; and in the {\em C.elegans} connectome, we are able to distinguish between chemical and electrical networks. The latter example is a concrete demonstration that our test can have power even for small sample sizes. We conclude by discussing the relationship between our test procedure and generalized likelihood ratio tests. 
Minh Tang, Avanti Athreya, Daniel L. Sussman, Vince Lyzinski, and   Carey E. Priebe
stat.ME