Single-shot MeV transmission electron microscopy with picosecond   temporal resolution
  Pushing the limits in temporal resolution for transmission electron microscopy (TEM) requires a revolutionary change in the electron source technology. In this paper we study the possibility of employing a radiofrequency photoinjector as the electron source for a time-resolved TEM. By raising the beam energy to the relativistic regime we minimize the space charge effects which otherwise limit the spatio-temporal resolution of the instrument. Analysis and optimization of the system taking into account the achievable beam brightness, electron flux on the sample, chromatic and spherical aberration of the electron optic system, and space charge effects in image formation are presented and supported by detailed numerical modeling. The results demonstrate the feasibility of 10 nanometer - 10 picosecond spatio-temporal resolution single-shot MeV TEM. 
R. K. Li and P. Musumeci
physics.acc-ph