A Reinforcement Learning System to Encourage Physical Activity in   Diabetes Patients
  Regular physical activity is known to be beneficial to people suffering from diabetes type 2. Nevertheless, most such people are sedentary. Smartphones create new possibilities for helping people to adhere to their physical activity goals, through continuous monitoring and communication, coupled with personalized feedback.   We provided 27 sedentary diabetes type 2 patients with a smartphone-based pedometer and a personal plan for physical activity. Patients were sent SMS messages to encourage physical activity between once a day and once per week. Messages were personalized through a Reinforcement Learning (RL) algorithm which optimized messages to improve each participant's compliance with the activity regimen. The RL algorithm was compared to a static policy for sending messages and to weekly reminders.   Our results show that participants who received messages generated by the RL algorithm increased the amount of activity and pace of walking, while the control group patients did not. Patients assigned to the RL algorithm group experienced a superior reduction in blood glucose levels (HbA1c) compared to control policies, and longer participation caused greater reductions in blood glucose levels. The learning algorithm improved gradually in predicting which messages would lead participants to exercise.   Our results suggest that a mobile phone application coupled with a learning algorithm can improve adherence to exercise in diabetic patients. As a learning algorithm is automated, and delivers personalized messages, it could be used in large populations of diabetic patients to improve health and glycemic control. Our results can be expanded to other areas where computer-led health coaching of humans may have a positive impact. 
Irit Hochberg and Guy Feraru and Mark Kozdoba and Shie Mannor and   Moshe Tennenholtz and Elad Yom-Tov
cs.CY cs.LG