Observation of dynamics inside an unlabeled live cell using bright-field   photon microscopy: Evaluation of organelles' trajectories
  This article presents an algorithm for the evaluation of organelles' movements inside of an unmodified live cell. We used a time-lapse image series obtained using wide-field bright-field photon transmission microscopy as an algorithm input. The benefit of the algorithm is the application of the R\'enyi information entropy, namely a variable called a point information gain, which enables to highlight the borders of the intracellular organelles and to localize the organelles' centers of mass with the precision of one pixel. 
Renata Rychtarikova and Dalibor Stys
q-bio.QM cs.CV q-bio.CB q-bio.SC