Deep Amortized Inference for Probabilistic Programs
  Probabilistic programming languages (PPLs) are a powerful modeling tool, able to represent any computable probability distribution. Unfortunately, probabilistic program inference is often intractable, and existing PPLs mostly rely on expensive, approximate sampling-based methods. To alleviate this problem, one could try to learn from past inferences, so that future inferences run faster. This strategy is known as amortized inference; it has recently been applied to Bayesian networks and deep generative models. This paper proposes a system for amortized inference in PPLs. In our system, amortization comes in the form of a parameterized guide program. Guide programs have similar structure to the original program, but can have richer data flow, including neural network components. These networks can be optimized so that the guide approximately samples from the posterior distribution defined by the original program. We present a flexible interface for defining guide programs and a stochastic gradient-based scheme for optimizing guide parameters, as well as some preliminary results on automatically deriving guide programs. We explore in detail the common machine learning pattern in which a 'local' model is specified by 'global' random values and used to generate independent observed data points; this gives rise to amortized local inference supporting global model learning. 
Daniel Ritchie, Paul Horsfall, Noah D. Goodman
cs.AI cs.LG stat.ML