High-Resolution Directed Human Connectomes and the Consensus Connectome   Dynamics
  Here we show a method of directing the edges of the connectomes, prepared from diffusion tensor imaging (DTI) datasets from the human brain. Before the present work, no high-definition directed braingraphs (or connectomes) were published, because the tractography methods in use are not capable of assigning directions to the neural tracts discovered. Previous work on the functional connectomes applied low-resolution functional MRI-detected statistical causality for the assignment of directions of connectomes of typically several dozens of vertices. Our method is based on the phenomenon of the "Consensus Connectome Dynamics" (CCD), described earlier by our research group. In this contribution, we apply the method to the 423 braingraphs, each with 1015 vertices, computed from the public release of the Human Connectome Project, and we also made the directed connectomes publicly available at the site \url{http://braingraph.org}. We also show the robustness of our edge directing method in four independently chosen connectome datasets: we have found that 86\% of the edges, which were present in all four datasets, get the very same directions in all datasets; therefore the direction method is robust, it does not depend on the particular choice of the dataset. We think that our present contribution opens up new possibilities in the analysis of the high-definition human connectome: from now on we can work with a robust assignment of directions of the connections of the human brain. 
Bal\'azs Szalkai and Csaba Kerepesi and B\'alint Varga and Vince   Grolmusz
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