Mechanosensitive Ion Channels in Cardiovascular Physiology.
Exp Clin Cardiol 2014;20(10):6550-6560. Epub 2014 Oct 29.
Laboraotry of Cell and Molecular Biology, University of Wisconsin - Madison, WI 53706, USA; Department of Genetics, University of Wisconsin - Madison, WI 53706.
Detection of left ventricular asynchrony and its relationship with the Tei index in patients with coronary artery ectasia.
Objective: To evaluate left ventricular (LV) systolic asynchrony and its relationship with the Tei index using tissue Doppler imaging (TDI); and to evaluate the relationship of thrombolysis in myocardial infarction frame count (TFC) and Tei index with LV asynchrony in patients with coronary artery ectasia (CAE).
Smooth muscle-like cells resident in the media participate in spasm-induced coronary intimal hyperplasia.
Background: Coronary intimal hyperplasia occurs at the site of spasm in patients with vasospastic angina. The migration of vascular smooth muscle cells (VSMCs) from the media has been proposed as a potential mechanism; however, this has not been confirmed with supportive evidence.
Omega-3 polyunsaturated fatty acid-enriched diet differentially protects two subpopulations of myocardial mitochondria against Ca(2+)-induced injury.
Department of General and Molecular Pathophysiology, AA Bogomoletz Institute of Physiology, Kiev, Ukraine.
What lies beneath: Posterior ST elevation myocardial infarction with underlying right ventricular-paced rhythm.
Division of Cardiovascular Medicine, University of California, Davis, Davis, California, USA.
Patent ductus arteriosus closure using an Amplatzer(™) ventricular septal defect closure device.
University of Texas Health Science Center at Houston, Houston, Texas, USA.
Mitral annulus calcification is independently associated with all-cause mortality.
University of Arizona School of Medicine, Tucson, Arizona, USA.
Evaluation of left ventricular function, rotation, twist and untwist in patients with hypertrophic cardiomyopathy.
Abnormal myocardial perfusion and risk of heart failure in patients with type 2 diabetes mellitus.
HF Clinic, Instituto Nacional de Ciencias Médicas y Nutrición "Salvador Zubirán".
Background: Diabetes is a major risk factor for heart failure (HF), although the pathophysiological processes have not been clarified.
Objective: To determine the prevalence of HF and of abnormal myocardial perfusion in diabetic patients evaluated using technetium (99m) sestamibi single-photon emission computed tomography.
Atorvastatin improves endothelial progenitor cell function and reduces pulmonary hypertension in patients with chronic pulmonary heart disease.
Objective: To explore the effects of atorvastatin on the migration and adhesion of endothelial progenitor cells (EPCs) and on pulmonary artery pressure (PAP) in patients with chronic pulmonary heart disease.
Relationship between serum uric acid levels and ventricular function in patients with idiopathic pulmonary hypertension.
Objective: To investigate the relationship between serum uric acid levels and pulmonary hypertension in patients with idiopathic pulmonary artery hypertension (IPAH).
Background: Few studies have assessed the prevalence of mixed dyslipidemia (MD) and the effectiveness of lipid-modifying therapy (LMT) for the treatment of abnormal levels of low-density lipoprotein cholesterol (LDL-C), triglycerides (TG) and high-density lipoprotein cholesterol (HDL-C) in Australian clinical practice.
Objective: To estimate the prevalence of MD in Australian patients undergoing LMT.
Combined circumferential and longitudinal left ventricular systolic dysfunction in patients with type 2 diabetes mellitus without myocardial ischemia.
Background/objective: Left ventricular (LV) circumferential or longitudinal shortening may be impaired in patients with type 2 diabetes mellitus (DM). In the present study, patients with type 2 DM without myocardial ischemia and combined impairment of circumferential and longitudinal (C+L) shortening were studied to assess the prevalence and factors associated with this condition.
How do cardiorespiratory fitness improvements vary with physical training modality in heart failure patients? A quantitative guide.
University of New England, School of Science and Technology, Armidale, New South Wales, Australia.
Background: Peak oxygen consumption (VO2) is the gold standard measure of cardiorespiratory fitness and a reliable predictor of survival in chronic heart failure patients. Furthermore, any form of physical training usually improves cardiorespiratory fitness, although the magnitude of improvement in peak VO2 may vary across different training prescriptions.
High prevalence of subclinical thyroid dysfunction and the relationship between thyrotropin levels and cardiovascular risk factors in residents of the coastal area of China.
Objectives: To investigate the prevalence of subclinical thyroid dysfunction and the relationship between thyrotropin levels and cardiovascular risk factors in residents of the coastal area of China.
Hematological parameters and coronary collateral circulation in patients with stable coronary artery disease.
Abant Izzet Baysal University School of Medicine, Department of Cardiology, Bolu, Turkey.
Background: Although hematological parameters have been associated with prognosis in patients with various cardiovascular diseases, their relationship with coronary collateral (CC) circulation in patients with stable coronary artery disease (CAD) is unknown.
Objective: To investigate the relationship between hematological parameters and CC vessel development in patients with stable CAD.
Left ventricular systolic and diastolic function in subjects with a bicuspid aortic valve without significant valvular dysfunction.
Cardiology Department, Bursa Yüksek htisas Education and Research Hospital, Bursa, Turkey.
Background: The bicuspid aortic valve (BAV) represents the most common cardiac congenital malformation in adults. It is frequently associated with dilation, aneurysm and dissection of the ascending aorta.
Role of gamma-glutamyltransferase in cardiovascular diseases.
Department of Cardiology, the Third Affiliated Hospital to Nantong University, Wuxi, Jiangsu Province, China.
A novel measurement technique for the design of fenestrated stent grafts: Comparison with three-dimensional aorta models.
Validation of the vitronectin knockout mouse as a model for studying myocardial infarction: Vitronectin appears to influence left ventricular remodelling following myocardial infarction.
Department of Pathology and Laboratory Medicine, University of British Columbia and the James Hogg iCAPTURE Centre for Cardiovascular and Pulmonary Research, St Paul's Hospital, Vancouver, British Columbia.
Background: Vitronectin (VN) is an abundant acute-phase plasma protein that regulates cell adhesion and migration as well as interactions with components of the plasminogen activator/plasmin system, specifically plasminogen activator inhibitor type 1. This system plays a major role in tissue remodelling regulating wound healing after myocardial infarction.
Effect of the stellate ganglion on atrial fibrillation and atrial electrophysiological properties and its left-right asymmetry in a canine model.
Objective: To investigate the effect of the stellate ganglion (SG) and its left-right asymmetry on atrial fibrillation (AF) inducibility, AF duration and atrial electrophysiological properties.
Department of Cardiology, University of South Alabama, Mobile, Alabama, USA.
Right ventricular myocardial infarction: From pathophysiology to prognosis.
Department of Internal Medicine and Cardiology, Masaryk University and University Hospital Brno, Brno, Czech Republic.
Mitral valve repair versus replacement in simultaneous aortic and mitral valve surgery.
Department of Cardiovascular Surgery, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
Background: Double valve replacement for concomitant aortic and mitral valve disease is associated with substantial morbidity and mortality. Excellent results with valve repair in isolated mitral valve lesions have been reported; therefore, whether its potential benefits would translate into better outcomes in patients with combined mitral-aortic disease was investigated.
Percutaneous coronary intervention delays pacemaker implantation in coronary artery disease patients with established bradyarrhythmias.
Department of Cardiology, The Fourth Clinical Hospital of Harbin Medical University, Harbin, China.
Background: Pacemakers have long been used to assist the heart under pathological conditions, and they are the first choice in the treatment of systematic bradyarrhythmias. However, the effect of percutaneous coronary intervention (PCI) in patients with coronary artery disease as well as bradyarrhythmias remains unknown.
Effect of prostaglandin E1 inhalation on pulmonary hypertension following corrective surgery for congenital heart disease.
Background: Intravenous infusion of prostaglandin E1 (PGE1) has been used to treat pulmonary arterial hypertension (PAH); however, the efficacy and safety of inhaled PGE1 is unclear.
Objectives: To investigate the effect of inhaled PGE1 on PAH following corrective surgery for congenital heart disease.
Depression increases the risk for uncontrolled hypertension.
Metabolic and Research Clinic, Hospital General de Ticomán SS DF and Mexican Group for Basic and Clinical Research in Internal Medicine, México DF, México.
Background: Because hypertension and depression share common pathways, it is possible that each disease has an impact on the natural history of the other.
Objective: To determinate whether depression influences blood pressure control in hypertensive patients.
Effects of low-dose hydroxychloroquine on expression of phosphorylated Akt and p53 proteins and cardiomyocyte apoptosis in peri-infarct myocardium in rats.
Division of Cardiology, Department of Geriatrics, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China ; Laboratory Research Center, The First Affiliated Hospital of Chongqing Medical University, Chongqing, People's Republic of China.
Background: Low-dose hydroxychloroquine (HCQ) and ataxia-telangiectasia-mutated (ATM) protein kinase have recently been postulated to be beneficial for the prevention of the age-associated metabolic syndrome including hypertension, hypercholesterolemia and glucose intolerance; however, the effects of low-dose HCQ on the expression of ATM downstream phosphorylated Akt (protein kinase B) and p53 proteins and cardiomyocyte apoptosis in the peri-infarct myocardium remain unclear.
Objective: To explore the effects of low-dose HCQ on the expression of phosphorylated Akt and p53 proteins and cardiomyocyte apoptosis in the peri-infarct myocardium in a rat model.
Exercise-induced ST-segment elevation during the recovery phase of an exercise stress test.
Oxidative stress: Predictive marker for coronary artery disease.
Third Medical Faculty of Charles University and University Hospital Royal Vineyards, Prague, Czech Republic.
Nitrate-induced paradoxical ischemia predicts adverse outcomes in elderly patients with healed myocardial infarcts.
Nuclear Cardiology Service, Università Campus - Bio Medico di Roma, Via Alvaro del Portillo, Rome, Italy.
Background: It is well known that nitrates can induce paradoxical myocardial ischemia.
Correlation between major adverse cardiac events and coronary plaque characteristics.
Background: Unstable plaque is believed to be responsible for major adverse cardiac events (MACE).
Objective: To determine whether coronary computed tomography angiography (CCTA) could be used to predict future MACE.
Functions of cyclophilin A in atherosclerosis.
Department of Cardiology, No.3 People's Hospital affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.
A modified murine model for the study of reverse cardiac remodelling.
Division of Cardiothoracic Surgery, University of Utah, Salt Lake City, Utah, USA.
The effect of trans-resveratrol on platelet-neutrophil complex formation and neutrophil burst in hypercholesterolemic rats.
Department of Biochemistry, Faculty of Medicine, Bozok University, Antalya, Turkey.
The effects of cyclooxygenase and nitric oxide synthase inhibition on cardiodynamic parameters and coronary flow in isolated rat hearts.
Background: Despite the widespread clinical use of cyclooxygenase (COX) inhibitors, dilemmas regarding the potential impact of these drugs on the cardiovascular system persist.
Objective: To estimate the effects of different COX inhibitors (meloxicam, acetylsalicylic acid [ASA] and SC-560) on cardiac function and coronary flow in isolated rat hearts, with special focus on the L-arginine/nitric oxide system.
Effectiveness of a new inflatable balloon device for gluing dissected layers in an experimental model of aortic dissection.
Effect of metoprolol on myocardial apoptosis and caspase-9 activation after coronary microembolization in rats.
Department of Cardiology, The First Affiliated Hospital of Guangxi Medical University, Nanning, China.
Objective: To explore the effect of metoprolol on myocardial apoptosis and caspase-9 activation after coronary microembolization (CME) in rats.
Substrate-dependent modulation of oxidative phosphorylation in isolated mitochondria following in vitro hypoxia and reoxygenation injury.
Department of Anesthesiology, Sapporo Medical University School of Medicine, Sapporo, Japan.
Wenxin Keli suppresses atrial substrate remodelling after epicardial ganglionic plexi ablation.
Cardiovascular Research Institute of Wuhan Unviersity, Renmin Hospital of Wuhan University, China.
Background: The chronic effects of ganglionic plexi (GP) ablation on atrial fibrillation (AF) inducibility have not been elucidated.
Objective: To investigate the effect of Wenxin Keli (WK) on the inducibility of AF and atrial substrate remodelling after epicardial GP ablation.
Myocardial inflammation in polymyalgia rheumatica assessed using cardiac magnetic resonance imaging.
Chronic diarrhea as the initial clinical manifestation of light-chain amyloidosis with cardiac involvement despite negative duodenal and rectal biopsies.
University of Technology Dresden, Department of Internal Medicine and Cardiology, Heart Center Dresden, University Hospital, Dresden, Germany.
Pulmonary embolism, part II: Management.
2nd Department of Medicine, Department of Cardiovascular Medicine, General University Hospital and 1st Faculty of Medicine, Charles University in Prague, Prague, Czech Republic.
Pulmonary embolism, part I: Epidemiology, risk factors and risk stratification, pathophysiology, clinical presentation, diagnosis and nonthrombotic pulmonary embolism.
2nd Department of Medicine - Department of Cardiovascular Medicine, General University Hospital and 1st Faculty of Medicine, Charles University in Prague, Prague, Czech Republic.
High-sensitivity C-reactive protein levels and treadmill exercise test responses in men and women without overt heart disease.
The primary anomalies of coronary artery origin and course: A coronary angiographic analysis of 16,573 patients.
Ondokuz Mayis University, Faculty of Medicine, Cardiology Department, Samsun, Turkey.