Why is it difficult to import 5-HTP (a form of Tryptophan) into some countries? 5-Hydroxytryptophan(WP) is sold in various places around the world as a dietary supplement that may boost serotonin levels, with possible benefits as a sleep aid, antidepressant, appetite suppressant, and antidepressant. Everyone appears to respond to 5-HTP differently (and there are woefully few published standardized general trials on the amino acid's function), but I've found that my own body clock seems to respond quite positively to 5-HTP, with no noticeable side effects, and that taking 100mg a day for a week or two makes it much easier for my body to realign back to &quot;wake up early in the morning&quot; after my sleep cycle has been knocked around for an extended period. (Sample size of 1. YMMV.) Unfortunately, living in Australia, I've always noticed an extra bit of friction whenever I've ordered 5-HTP online (I've never seen it available for purchase anywhere locally in NSW). Some websites will notify me that &quot;this product cannot be shipped to your country&quot; at checkout time or list that they do not ship 5-HTP to Australia in their store policy. A few websites don't make much noise on the subject, accept my order, and ship it off Some sites will feature large Australian flags, draw attention to the fact that they're using AUD$, and drop similar hints, but won't actually say they ship to Australia. A few rare sites explicitly claim that they ship to AU, and don't make much fuss about it. Why the... weirdness? I understand the FDA banned L-Tryptophan after linking it to the 1989 Eosinophilia-Myalgia Syndrome(WP) outbreak, then relaxed the ban in 2001, allowing the use of L-Tryptophan (and 5-Hydroxytryptophan, aka oxytriptan). What happened over the last 19 years though? Every checkout experience feels like an event horizon, where I know something impactful happened but I can't find or trace the source of the impact. While I obviously have a bias towards understanding the friction I'm experiencing here in Australia, having a worldwide view would also be very interesting too. The only reference I've been able to turn up (mostly due to subject ignorance) is https://www.erowid.org/smarts/tryptophan/tryptophan_law.shtml - an old-looking page (apparently last modified 2015) that notes that 5-HTP is &quot;somewhat controlled&quot; in Australia, but doesn't cite why. Some online stores publish similar-sounding positive noises about 5-HTP's controlled status and availability. Wikipedia has no section on *tryptophan's worldwide availability. I remember reading at some point (I forget exactly where from unfortunately) that Australia generally accepts/allows small quantities of 5-HTP to be imported for personal use, and blocks/turns away larger quantities to prevent resale. I'm curious as to the historical narrative behind why this distinction is made. Fundamentally speaking, though, why is there friction? If possible, actual legal citations and references would be awesome. When I buy 5-HTP, it would be nice to not have to keep making exceptions to my rule about always hunting for whoever has the best going price at any given moment in time. It would be cool if I could online stores concrete references and assuage their fears and concerns.
From the legal perspective, the question is whether the substance is legal in Australia. The legal root of the matter is the Therapeutic Goods Administration. Dosages above 100 mg are on &quot;Schedule 4&quot; meaning they require a prescription. There are also apparently state regulations. In Queensland, there is an amendment to the Drugs Misuse Regulation 1987 to ensure that the substance 5-Hydroxy tryptophan (5-HTP) is captured in Schedule 2 with the exception of preparations that contain 100mg or less of 5-HTP per dosage unit Schedule 2 is &quot;Substances, the safe use of which may require advice from a pharmacist and which should be available from a pharmacy or, where a pharmacy service is not available, from a licensed person&quot;. The fact that it is very difficult to verify what the current regulations are may explain the &quot;friction&quot;, which may make online purchases difficult. The underlying reason for government regulation is to keep people safe. Politics SE is an appropriate place to debate the balance between safety and usefulness.
Does the said law (or any other law or treaty) prohibit Indians to get the pre-natal gender screening test done outside India (in any country where this is legal)? YES, in theory but I cannot find any relevant case law where this has been considered by the court. Section 23(3) of the Pre-Conception and Pre-natal Diagnostic Techniques (Prohibition of Sex Selection) Act 1994 (PCPNDT) creates the offence for non-medical practitioners etc: Any person who seeks the aid of any [medical practioner etc] or any other person for sex selection or for conducting pre-natal diagnostic techniques on any pregnant women for the purposes other than those specified in sub-section (2) of section 4, he shall, be punishable with imprisonment for a term which may extend to three years and with fine which may extend to fifty thousand rupees for the first offence and for any subsequent offence with imprisonment which may extend to five years and with fine which may extend to one lakh rupees. And section 4(1) of the Indian Penal Code (IPC) provides for extra-territorial jurisdiction for any offences committed by: any citizen of India in any place without and beyond India... Normally, criminal justice action would only be considered once the parties returned to India, but note that section 299 of the Code of Criminal Procedure 1973 allows for trials in absentia. However I cannot find any relevant case law to say whether this has actually happened in this type of scenario.
In the U.S., Law enforcement favors going after the distribution of narcotics over the use. Going after the users just means dealers will seek out new customers whereas going after dealers means eliminating the supply chain. And Law Enforcement would much rather have a dealer flip on a manufacturer at that. The bigger the fish they bring in, the more damage they can do to the supply chain. The U.S. has recently been moving towards treating the use of illicit substances as a disease rather than an crime, especially when the use is tied to addiction. To this end, the current trend is to get the users to clinics that can specialize in breaking addiction rather than jailing a user. Prisons and jails do not have a strong track record for this, but they do have programs for substance abuse. The U.S. also favors plea bargins rather than taking every case to trial. 90% of all legal cases are settled out of court with a negotiation between the prosecution and the defense. Usually this acts in a "you scratch my back" arrangement where the offender will plea to a lesser charge and in exchange, help the investigators find that bigger fish. This may be testifying against them or giving them the supplier or even acting as a mole. This also benifits the state as the prosecution doesn't have to pay for all the costs of arguing a case a trial. For example, if the cops bust a user, he will be charged with Possession, but they might drop charges if the user can name the dealer and will testify against him. If the cops bust the dealer, the dealer is charged with Possession (with intent to sell), but if he's low on the totem pole, they can ask him to name the supplier he gets his goods and testify against the supplier and in exchange, they drop the charge to Possession. They will be less inclined to bring this fact up, but Possession is easier to prove in court than Possession (With Intent to Sell) because the former requires finding drugs on the person and his property. The later needs to prove that the drugs were not for personal use but instead for distribution to others. Almost universally, anyone convicted on mere possession charges probably did something a lot worse. Law enforcement tends to charge as many crimes as possible... as long as they can prove guilt on one, they can put someone away for a while. Al Capone famously went to one of the most notorious prisons in the United States for Tax Evasion (a very white collared crime that typically results in fines and very minimum jail time. While we're on the subject, the IRS has a 98% conviction rate, and ties with Secret Service (the guys who protect the President) for most successful Federal Law Enforcement Agency, to give you an idea of where the priorities lie in the United States. All Federal Law Enforcement is ridiculously good, to the point that bringing charges against anyone is almost as good as saying they're guilty). Another reason Use of drugs isn't pushed is that, well, producing that evidence is difficult. The common user bust is drinking and driving (since alcohol is legal in the U.S., use based crimes are the top level of enforcement. You legally cannot hold a firearm in the U.S. while drunk, even if you could do so while sober). A brethalizer is built to measure the amount of alcohol is in one's system and if it is over the limit for what is safe. Most illicit drug tests don't do this and rather look for chemicals in general and will ping if there's any trace... even if the last use was a month ago. Certain substances linger for a while, especially if they can deposit in hair folicle. You could be six months sober and still ping the test. Other issuses include drugs that contain components of legal substances. Opiods (the big problem drug right now) are manufactured from the Poppy Plant... which also is grown for legal consumable products. There are cases where the Opiod tests pings positive on people who have consumed Poppy-Seed Bagels (perfectlly legal and quite common) for breakfast the day of the test. Other tests aren't reliable and will give a false positive from time to time. Edit: Typically, Possession of a controlled substance assumes you will use it. Reasonable Doubt is harder to make for having the stuff then it is for using it. Someone under the influence could claim they were drugged and law enforcement would have to prove that they weren't to convict (There's actually a known problem where law enforcement agents can get dosed by accident while handling contraband evidence. There was an episode of CSI: Miami where one character had this happen to her... and they realized where the drugs were hidden in a warehouse she served a warrant on but didn't find any evidence. DVD extras featured a police consultant who explained that the whole sequence was thought up because it happened to her for real.). Having the stuff in your possession is much more difficult as they have to show you had it (someone slipping it into your pocket without your knowledge is your job to prove). In the U.S., Prosecution Discretion means that the Prosecutor can choose not to press the case for any number of reasons, they don't have the resources to fight it, to they don't think they can win with the evidence they have, to political motives (they don't agree with the law... this can be risky depending on the nature of the crime). Typically a simple possession charge where the amount is clearly small enough that it's only for personal use and no other crimes are charged wouldn't be worth the amount of resources to fully prosecute. TO give an example, while Marijuana is legal in the State of Colorado, it's still illegal under Federal Law, so smoking for recreational use in Colorado is still a crime, but not one enforced by the State of Colorado but the Department of Justice (U.S. Federal Law enforcement department... usually). Remember the Feds generally deal with bigger crimes than someone getting high under the bleachers while listening to Jimmy Hendrix, so it only really comes up if you did something bigger (kidnapping a girl, driving over state lines into Colorado, go to a school to get high under the bleachers while listening to Hendrix would get you a Federal Possession charge... but the real concern is the Kidnapping, not controlled drug use). And most crimes that occur in entirely one state, Feds are content to let those states deal with the problem and rarely get involved.
According to the information I was able to find, every zone, country, or even states, have their own taxation rules for sales made there. Correct. Well, in no way it's possible that small companies or individuals that sell products internationally deal with tax rules for each buyer, that would be a non-sense, and paying such taxes worldwide would be a nightmare not worth having a small business at all. You are required to comply with the law. If it is complicated, or difficult or expensive to do so then, it's complicated, difficult and expensive and you still have to do it. The answer is obvious: if it's not worth having a small business, don't have a small business. The main question, if someone buys a license from my web-site, is it considered a sale in the buyer's country/state which requires me to collect and pay some remote tax, or it's a purchase in my country/state which requires me to collect HST from that buyer? It depends on the law in both Canada and the destination country. In most cases, the sale will be an export sale from Canada (GST/HST exempt) and an import sale in the destination country - requiring you to comply with GST/HST obligations there. Another question is regarding invoices, I know that Canada requires certain information to be included into an invoice for sales in Canada. If my sales will be considered sales in a buyer's Country with some other rules, does it mean I have to manage tons of invoice templates? Yes. Let's say if my sales in UE exceed 30K EUR it looks like I need to register and pay VAT there. But what if I have less? Then you don't need to register and remit tax. Nor are you allowed to collect it from your customers. By the way, I have no idea what country in the Eurozone goes by the initials UE. In most jurisdictions, you need to register either when you reach the threshold in fact or reasonably expect to reach the threshold. Also in most, you can usually register even if you are below the threshold. For example, these are the rules for Australia. Anyone, please advice. Hire an accountant versed in international digital services. They will be able to give you the advice you need. They will also be able to recommend sales/payment platforms that can handle most of this for you (for a fee, of course).
In the US, it depends on why you are doing this, and how you go about performing the operation. There are approved devices and procedures, and there is the other stuff. In an emergency that is life-threatening or threatens severe debilitation, it is permitted for a physician to try an extreme measure – if the state has a "Right to Try" law. Otherwise, a review and official approval by the relevant IRB is required. The devices are regulated by the FDA, but the FDA does not regulate the practice of medicine, so the feds don't have a say in whether a procedure is allowed. Nevertheless, use of unapproved devices can be taken to be evidence of failing to meet the required standard of care, in the case of a malpractice suit or punitive action by the state regulatory board. There is no specific law prohibiting removing lots of organs and replacing them with prostheses, though arguable what happened was that the brain was removed (it's not that a replacement shell was built around the person). Ordinarily, intentionally "killing" a person is illegal (except in case of sanctioned execution or self-defense). There is zero case law that would tell us whether removing a brain from a body "kills" the person. Most likely, there would be a prosecution for unlawfully causing a death, and either the legislature would tune up the law w.r.t. the definition of "causing death", or the courts would do so.
Your terms and conditions must comply with the laws in: Your jurisdiction (California) Your customer's jurisdiction (each of the US states, Canadian provinces and ultimately countries and sub-jurisdictions in Europe) If they do they will generally be enforceable; if they don't then they will not be enforceable and you may be exposing yourself to civil and criminal sanctions. While not immediately relevant to you, Australian Consumer Law has such sanctions to goods sold into Australia from anywhere in the world; I am not familiar with other jurisdictions. With respect to your comment that you will not accept returns or refunds, this would expose you to potential fines in Australia of $220,000 for an individual or $1,100,000 for a corporation - under Australian Consumer Law returns and refunds are a consumer right. I strongly suspect that most of the jurisdictions you are selling into would take a similar position. A general "catch-all" like "to the extent permitted by law" may reduce the risk of being prosecuted but it would not eliminate it entirely. Again, in Australia, the provision is that you must not engage in deceptive and misleading conduct - merely suggesting that you will not give a refund even with the limitation above - may still be deemed "deceptive and misleading" if the court feels that a reasonable consumer might assume that they are not entitled to a refund. You need professional legal advice on this.
Article 8 is pretty clear. The fact that it is recommended to extend the draft to women indicates that there is a conflict needing resolution. A relevant case before the European Court of Human Rights ruled on this and found the law to violate articles 14 and 8 of the ECHR. They identify an exoneration from the tax under the Military-Service Exemption Tax Act sect. 4. Reading the judgment could be helpful (maybe you know the case). What I get from it is that there are a bunch of situation-specific details that could be applied (e.g. you have to first complain formally in-country before going to ECHR), and issues of disability level and the distinction between disability and illness. This gives a model for anyone to attempt to resist the tax, but only a change in the law will get rid of it.
Why would the FDA limit actionable material that may enhance treatment? Because the FDA has a bunch of regulations that say if you are going to sell a medical test you first have to prove that it is safe, accurate, and effective. The genome scan companies first had to prove that their genome scans were accurate and had sufficient quality controls built in. In addition, the typical results from a genome scan involve a lot of ambiguity, and probabilistic measurements of relative risk, so there was a huge question of whether the automated reports produced by these companies would actually be accurate, intelligible, and not promise too much or too little to the consumer. The company, Sure Genomics, in the article you linked too, apparently avoids this issue by having a physician review the report, and consult with the consumer. Other companies tried to completely automate the process and didn't include the physician consultation. As least one company, 23andMe, has, at least partially, worked out it's issues with the FDA and can provide medical reports on some conditions.