diff --git a/.gitattributes b/.gitattributes new file mode 100644 index 0000000000000000000000000000000000000000..d3ad19eb28837e7e93597c2e155cf814a506c9d2 --- /dev/null +++ b/.gitattributes @@ -0,0 +1,67 @@ +*.7z filter=lfs diff=lfs merge=lfs -text +*.arrow filter=lfs diff=lfs merge=lfs -text +*.bin filter=lfs diff=lfs merge=lfs -text +*.bz2 filter=lfs diff=lfs merge=lfs -text +*.ckpt filter=lfs diff=lfs merge=lfs -text +*.ftz filter=lfs diff=lfs merge=lfs -text +*.gz filter=lfs diff=lfs merge=lfs -text +*.h5 filter=lfs diff=lfs merge=lfs -text +*.joblib filter=lfs diff=lfs merge=lfs -text +*.lfs.* filter=lfs diff=lfs merge=lfs -text +*.lz4 filter=lfs diff=lfs merge=lfs -text +*.mlmodel filter=lfs diff=lfs merge=lfs -text +*.model filter=lfs diff=lfs merge=lfs -text +*.msgpack filter=lfs diff=lfs merge=lfs -text +*.npy filter=lfs diff=lfs merge=lfs -text +*.npz filter=lfs diff=lfs merge=lfs -text +*.onnx filter=lfs diff=lfs merge=lfs -text +*.ot filter=lfs diff=lfs merge=lfs -text +*.parquet filter=lfs diff=lfs merge=lfs -text +*.pb filter=lfs diff=lfs merge=lfs -text +*.pickle filter=lfs diff=lfs merge=lfs -text +*.pkl filter=lfs diff=lfs merge=lfs -text +*.pt filter=lfs diff=lfs merge=lfs -text +*.pth filter=lfs diff=lfs merge=lfs -text +*.rar filter=lfs diff=lfs merge=lfs -text +*.safetensors filter=lfs diff=lfs merge=lfs -text +saved_model/**/* filter=lfs diff=lfs merge=lfs -text +*.tar.* filter=lfs diff=lfs merge=lfs -text +*.tar filter=lfs diff=lfs merge=lfs -text +*.tflite filter=lfs diff=lfs merge=lfs -text +*.tgz filter=lfs diff=lfs merge=lfs -text +*.wasm filter=lfs diff=lfs merge=lfs -text +*.xz filter=lfs diff=lfs merge=lfs -text +*.zip filter=lfs diff=lfs merge=lfs -text +*.zst filter=lfs diff=lfs merge=lfs -text +*tfevents* filter=lfs diff=lfs merge=lfs -text +# Audio files - uncompressed +*.pcm filter=lfs diff=lfs merge=lfs -text +*.sam filter=lfs diff=lfs merge=lfs -text +*.raw filter=lfs diff=lfs merge=lfs -text +# Audio files - compressed +*.aac filter=lfs diff=lfs merge=lfs -text +*.flac filter=lfs diff=lfs merge=lfs -text +*.mp3 filter=lfs diff=lfs merge=lfs -text +*.ogg filter=lfs diff=lfs merge=lfs -text +*.wav filter=lfs diff=lfs merge=lfs -text +# Image files - uncompressed +*.bmp filter=lfs diff=lfs merge=lfs -text +*.gif filter=lfs diff=lfs merge=lfs -text +*.png filter=lfs diff=lfs merge=lfs -text +*.tiff filter=lfs diff=lfs merge=lfs -text +# Image files - compressed +*.jpg filter=lfs diff=lfs merge=lfs -text +*.jpeg filter=lfs diff=lfs merge=lfs -text +*.webp filter=lfs diff=lfs merge=lfs -text +manual_annotations/test_set_m4_0_label.nii filter=lfs diff=lfs merge=lfs -text +manual_annotations/test_set_m4_0.nii filter=lfs diff=lfs merge=lfs -text +manual_annotations/test_set_m4_1_label.nii filter=lfs diff=lfs merge=lfs -text +manual_annotations/test_set_m4_1.nii filter=lfs diff=lfs merge=lfs -text +manual_annotations/test_set_m44_0_label.nii filter=lfs diff=lfs merge=lfs -text +manual_annotations/test_set_m44_0.nii filter=lfs diff=lfs merge=lfs -text +manual_annotations/test_set_m44_1_label.nii filter=lfs diff=lfs merge=lfs -text +manual_annotations/test_set_m44_1.nii filter=lfs diff=lfs merge=lfs -text +manual_annotations/test_set_m78_0_label.nii filter=lfs diff=lfs merge=lfs -text +manual_annotations/test_set_m78_0.nii filter=lfs diff=lfs merge=lfs -text +manual_annotations/test_set_m78_1_label.nii filter=lfs diff=lfs merge=lfs -text +manual_annotations/test_set_m78_1.nii filter=lfs diff=lfs merge=lfs -text diff --git a/README.md b/README.md new file mode 100644 index 0000000000000000000000000000000000000000..f9d5bbabba0ffee6abac89f478e3c7b6c502e9c3 --- /dev/null +++ b/README.md @@ -0,0 +1,68 @@ +--- +task_categories: +- image-segmentation +language: +- en +tags: +- medical +- blood-vessel +- octa +pretty_name: (Simulation-Based Segmentation of Blood Vessels in Cerebral 3D OCTA Images +size_categories: +- 1K + + + +## Introduction + +To accurately segment blood vessels in cerebral 3D Optical Coherence Tomography Angiography (OCTA) images, a vast amount of voxel-level annotations are required. However, the curation of manual annotations is a cumbersome and time-consuming task. To alleviate the need for manual annotation, we provide realistic synthetic data generated via our proposed synthesis pipeline. + +Our proposed synthesis pipeline is described in detail in our manuscript ([Simulation-Based Segmentation of Blood Vessels in Cerebral 3D OCTA Images](https://arxiv.org/abs/2403.07116)). Corresponding code and additional information can be found on [GitHub](https://github.com/bwittmann/syn-cerebral-octa-seg). + +**TL;DR:** *First*, we selectively extract patches from vessel graphs that match the FOV and morphological characteristics of vasculature contained in cerebral OCTA images and transform them into voxelized volumes; *second*, we transform the voxelized volumes into synthetic cerebral 3D OCTA images by simulating the most dominant image acquisition artifacts; and *third*, we use our synthetic cerebral 3D OCTA images paired with their matching ground truth labels to train a blood vessel segmentation network. + +## Dataset Summary +The voxel size of all provided images is isotropic and corresponds to 2 μm. + +- [synthetic cerebral 3D OCTA images with metadata & matching ground truth labels of shape 250 x 250 x 250; full data available upon request.](https://huggingface.co/datasets/bwittmann/syn-cerebral-octa-seg/tree/main/synthetic_cerebral_octa) +``` +synthetic_cerebral_octa/ +└── sample_0/ + └── sim/ + └── sim_data_xx.npy # synthetic cerebral 3D OCTA image + └── sim_seg_xx.npy # ground truth + └── ang.npy # metadata angle + └── occ.npy # metadata occupancy below + └── rad.npy # metadata radius + └── seg.npy # voxelized volume +└── sample_1/ + ... +``` + + +- [6 manually annotated OCTA volumes of shape shape 160 x 160 x 160.](https://huggingface.co/datasets/bwittmann/syn-cerebral-octa-seg/tree/main/manual_annotations) +``` +manual_annotations/ +└── mx_0.nii # real cerebral 3D OCTA image +└── mx_0_label.nii # ground truth (manual annotations) + ... +``` + + +## Citation + +If you find our data useful for your research, please consider citing: +```bibtex +@inproceedings{wittmann2024simulation, + title={Simulation-based segmentation of blood vessels in cerebral 3D OCTA images}, + author={Wittmann, Bastian and Glandorf, Lukas and Paetzold, Johannes C and Amiranashvili, Tamaz and W{\"a}lchli, Thomas and Razansky, Daniel and Menze, Bjoern}, + booktitle={International Conference on Medical Image Computing and Computer-Assisted Intervention}, + pages={645--655}, + year={2024}, + organization={Springer} +} +``` diff --git a/docs/synthetic3d.jpg b/docs/synthetic3d.jpg new file mode 100644 index 0000000000000000000000000000000000000000..513afd9a6148e4de38ccae068b207e66a0ad97f8 --- /dev/null +++ b/docs/synthetic3d.jpg @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:c50557d78f16bf06e45e3a6dc7073d9c95f91c0371aac3d7f85909205f92928e +size 524045 diff --git a/manual_annotations/test_set_m44_0.nii b/manual_annotations/test_set_m44_0.nii new file mode 100644 index 0000000000000000000000000000000000000000..5b7fc71ea7d340c9e9931930f44e42eaeebb2bd4 --- /dev/null +++ b/manual_annotations/test_set_m44_0.nii @@ -0,0 +1,3 @@ +version https://git-lfs.github.com/spec/v1 +oid sha256:131f5fbd4fe138ce21059f83f3cda6481494b98c58c2cbdcc32387559a4853e3 +size 16384352 diff --git 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