Acquisition of an X-ray Diffractometer and Area Detector
{'Code': '08000000', 'Directorate': {'Abbreviation': 'BIO', 'LongName': 'Direct For Biological Sciences'}, 'Division': {'Abbreviation': 'BIO', 'LongName': 'Direct For Biological Sciences'}}
{'SignBlockName': 'Kathie L. Olsen', 'PO_EMAI': None, 'PO_PHON': None}
An x-ray diffractometer and area detector will be acquired.  A                  wide variety of biological projects will be supported by the new                equipment.  Among the projects to be supported are further                      studies on crambin, a hydrophobic plant protein; purothionin, a                 hemolytic toxin from wheat; kringle 4, a fragment of the enzyme                 plasminogen; phycocyanin, a light harvesting antenna bacterial                  protein; and mutant aspartate transcarbamylases, an enzyme                      important in pyrimidine metabolism; natural products; synthetic                 receptors for organic molecules; metal ion complexes with nucleic               acids; metal ions bound to coenzymes.  These crystallographic                   studies on small molecules and other macromolecules will be                     combined with numerous other techniques such as CD, Raman, NMR                  and ESR spectroscopy; equilibrium binding assays and enzymatic                  kinetics; organic synthesis; computer graphics and molecular                    mechanics and structural prediction.  On the whole, the intent is               to look at structure-function relationships, integrating static                 structural information with dynamic information to gain a more                  complete understanding of macromolecular function.  The                         crystallographic structural determination will also serve as an                 important adjunct to organic synthesis of natural products and to               the design of synthetic receptors.
[{'FirstName': 'Martha', 'LastName': 'Teeter', 'PI_MID_INIT': 'M', 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'Martha M Teeter', 'EmailAddress': 'teeter@bc.edu', 'NSF_ID': '000093155', 'StartDate': '09/15/1987', 'EndDate': None, 'RoleCode': 'Principal Investigator'}, {'FirstName': 'Michael', 'LastName': 'Clarke', 'PI_MID_INIT': 'J', 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'Michael J Clarke', 'EmailAddress': 'clarke@bc.edu', 'NSF_ID': '000394469', 'StartDate': '09/15/1987', 'EndDate': None, 'RoleCode': 'Co-Principal Investigator'}, {'FirstName': 'T. Ross', 'LastName': 'Kelly', 'PI_MID_INIT': None, 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'T. Ross Kelly', 'EmailAddress': 'ross.kell@bc.edu', 'NSF_ID': '000460895', 'StartDate': '09/15/1987', 'EndDate': None, 'RoleCode': 'Co-Principal Investigator'}, {'FirstName': 'Evan', 'LastName': 'Kantrowitz', 'PI_MID_INIT': 'R', 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'Evan R Kantrowitz', 'EmailAddress': 'evan.kantrowitz@bc.edu', 'NSF_ID': '000102919', 'StartDate': '09/15/1987', 'EndDate': None, 'RoleCode': 'Co-Principal Investigator'}]
{'Name': 'Boston College', 'CityName': 'CHESTNUT HILL', 'ZipCode': '024673800', 'PhoneNumber': '6175528000', 'StreetAddress': '140 COMMONWEALTH AVE', 'StreetAddress2': None, 'CountryName': 'United States', 'StateName': 'Massachusetts', 'StateCode': 'MA', 'CONGRESSDISTRICT': '04', 'CONGRESS_DISTRICT_ORG': 'MA04', 'ORG_UEI_NUM': 'MJ3JH8CRJBZ7', 'ORG_LGL_BUS_NAME': 'TRUSTEES OF BOSTON COLLEGE', 'ORG_PRNT_UEI_NUM': None}
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{'Code': '1108', 'Text': 'INSTRUMENTAT & INSTRUMENT DEVP'}
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