Presidential Young Investigator Award:  Synthetic Models of Large Molecule-Small Molecule Interaction (Chemistry)
{'Code': '03090003', 'Directorate': {'Abbreviation': 'MPS', 'LongName': 'Direct For Mathematical & Physical Scien'}, 'Division': {'Abbreviation': 'CHE', 'LongName': 'Division Of Chemistry'}}
{'SignBlockName': 'John S. Showell', 'PO_EMAI': None, 'PO_PHON': None}
Dr. Armstrong is being given the Presidential Young                             Investigator Award from the Organic and Macromolecular                          Chemistry Program to support his research into the                              molecular-level interactions of proteins, DNA, RNA and small                    molecules.  This work will provide the information required to                  synthesize the new generation molecules to be used in                           agriculture and medicine.                                                                                                                                       The synthesis of modified polysaccaride is being undertaken to                  provide a means of controlling the linear distance between                      peptides and other substances in water soluble systems.  A                      small DNA fragment has been synthesized that contains an                        internal "handle" to provide a better understanding of the                      local and global chiral environment of DNA.  These two                          projects, if successful, will guide further work of the                         important interactions that are important in biochemical                        systems.  In addition, the synthesis of the structurally                        interesting natural products echinosporin, calyculin A and                      carzinophilin are being synthesized.  These will improve the                    understanding of the important DNA-inactivation processes.
{'FirstName': 'Robert', 'LastName': 'Armstrong', 'PI_MID_INIT': 'W', 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'Robert W Armstrong', 'EmailAddress': None, 'NSF_ID': '000370696', 'StartDate': '07/28/1993', 'EndDate': None, 'RoleCode': 'Principal Investigator'}
{'Name': 'University of California-Los Angeles', 'CityName': 'LOS ANGELES', 'ZipCode': '900244200', 'PhoneNumber': '3107940102', 'StreetAddress': '10889 WILSHIRE BLVD STE 700', 'StreetAddress2': None, 'CountryName': 'United States', 'StateName': 'California', 'StateCode': 'CA', 'CONGRESSDISTRICT': '36', 'CONGRESS_DISTRICT_ORG': 'CA36', 'ORG_UEI_NUM': 'RN64EPNH8JC6', 'ORG_LGL_BUS_NAME': 'UNIVERSITY OF CALIFORNIA, LOS ANGELES', 'ORG_PRNT_UEI_NUM': None}
{'Name': 'University of California-Los Angeles', 'CityName': 'LOS ANGELES', 'StateCode': 'CA', 'ZipCode': '900244200', 'StreetAddress': '10889 WILSHIRE BLVD STE 700', 'CountryCode': 'US', 'CountryName': 'United States', 'StateName': 'California', 'CountryFlag': '1', 'CONGRESSDISTRICT': '36', 'CONGRESS_DISTRICT_PERF': 'CA36'}
[{'Code': '1948', 'Text': 'SYNTHESIS'}, {'Code': '1950', 'Text': 'METHODOLOGY'}]
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