The Role of a-Lactalbumin in Lactose Biosynthesis
{'Code': '08070400', 'Directorate': {'Abbreviation': 'BIO', 'LongName': 'Direct For Biological Sciences'}, 'Division': {'Abbreviation': 'MCB', 'LongName': 'Div Of Molecular and Cellular Bioscience'}}
{'SignBlockName': 'Arthur Kowalsky'}
Lactose is synthesized in high levels only in the lactating                     mammary gland.  The enzyme complex "lactose synthase" is                        composed of two subunits, a glycosyl transferase called                         galactosyl transferase and a modifier protein, a-lactalbumin.                                                                                                   Using the techniques of fluorescence, ESR and NMR, Dr.                          Berliner will characterize, assign and map specific cation                      binding and other regions on the  a-lactalbumin molecule in                     solution.  Kinetic experiments will also be employed to test                    the efficacy of modified calcium binding loop derivatives in                    lactose biosynthesis.
{'FirstName': 'Lawrence', 'LastName': 'Berliner', 'EmailAddress': 'berliner@du.edu', 'StartDate': '11/01/1987', 'EndDate': None, 'RoleCode': 'Principal Investigator'}
{'Name': 'Ohio State University', 'CityName': 'Columbus', 'ZipCode': '432101016', 'PhoneNumber': '6146888735', 'StreetAddress': 'Office of Sponsored Programs', 'CountryName': 'United States', 'StateName': 'Ohio', 'StateCode': 'OH'}
[{'Code': '1144', 'Text': 'Molecular Biophysics'}, {'Code': '9120', 'Text': 'CROSS-DIRECTORATE PROGRAMS'}]
{'url': 'https://www.nsf.gov/awardsearch/download?DownloadFileName=1987&All=true', 'xml': '8703794.xml'}