Mediation of Calcium Homeostasis During Embryogenesis
{'Code': '08090300', 'Directorate': {'Abbreviation': 'BIO', 'LongName': 'Direct For Biological Sciences'}, 'Division': {'Abbreviation': 'IOS', 'LongName': 'Division Of Integrative Organismal Systems'}}
{'SignBlockName': 'Sharon Emerson'}
Dr. Packard plans to assess the relationship between transport of               calcium across the chrioallantoic membrane of chicken and other bird            eggs and maintenance of calcium homeostasis during embryogenesis.  The          research will examine the effect of perturbation of calcium transport           on calcium metabolism of intact chicken embryos during normal                   incubation.  Experiments address the role of carbonic anhydrase in              calcium metabolism, the effect of inhibition of carbonic anhydrase              activity on action of the hormonal form of vitamin D, the ability of            this hormone to increase transport of calcium to embryos, and the               importance of vitamin K to maintenance of calcium homeostasis.  The             plan is to identify those components of the transport system that are           most critical to normal function and those aspects of calcium                   metabolism that are most sensitive to perturbation, and will provide new        information on the mechanisms involved in regulation of calcium                 metabolism.  Results will enable integration of the data on the                 biochemistry of calcium metabolism during embryogenesis.  These studies         will provide comparative information on calcium metabolism in chicken           embryos and embryos of another species that produces precocial young            (Canada geese) as well as a species that produces altricial young               (yellowheaded blackbirds).
{'FirstName': 'Mary', 'LastName': 'Packard', 'EmailAddress': 'kpackard@lamar.colostate.edu', 'StartDate': '07/09/1993', 'EndDate': None, 'RoleCode': 'Principal Investigator'}
{'Name': 'Colorado State University', 'CityName': 'Fort Collins', 'ZipCode': '805232002', 'PhoneNumber': '9704916355', 'StreetAddress': '601 S Howes St', 'CountryName': 'United States', 'StateName': 'Colorado', 'StateCode': 'CO'}
[{'Code': '1141', 'Text': 'PHYSIOLOG & STRUCTURAL SYS'}, {'Code': '1148', 'Text': 'ECOLOGICAL & EVOLUTIONARY PHYS'}]
{'url': 'https://www.nsf.gov/awardsearch/download?DownloadFileName=1987&All=true', 'xml': '8718191.xml'}