Segmental Integration of Spinal Cord Descending 5HT and NE  Neuron Function
{'Code': '08090200', 'Directorate': {'Abbreviation': 'BIO', 'LongName': 'Direct For Biological Sciences'}, 'Division': {'Abbreviation': 'IOS', 'LongName': 'Division Of Integrative Organismal Systems'}}
{'SignBlockName': 'Christopher Comer', 'PO_EMAI': None, 'PO_PHON': None}
The spinal cord of mammals is an extremely complex structure               and serves a variety of important functions for controlling                     sensory input and motor output for the behaving animal.  There                  are numerous neurotransmitters and modulators within the spinal                 cord of mammals and the knowledge of their interactions is                      crucial to our understanding of how the spinal cord works.  Dr.                 David Jones is studying the interaction between two spinal                      (monoaminergic) transmitter systems, namely the norepinephrine                  and serotonergic systems.  His major hypothesis is that the                     norepinephrine and serotonin systems coregulate each other in                   spinal cord providing for integration between normal circuitry of               descending monoaminergic systems.  The approach he uses to                      investigate the pharmacology of these systems is the spinal slice               technique.  This work is important since it should add to our                   building body of knowledge of spinal motor circuits and how they                are regulated by combinations of neurotransmitters.
{'FirstName': 'David', 'LastName': 'Jones', 'PI_MID_INIT': 'J', 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'David J Jones', 'EmailAddress': None, 'NSF_ID': '000366118', 'StartDate': '08/01/1989', 'EndDate': None, 'RoleCode': 'Principal Investigator'}
{'Name': 'University of Texas Health Science Center San Antonio', 'CityName': 'SAN ANTONIO', 'ZipCode': '782293901', 'PhoneNumber': '2105672340', 'StreetAddress': '7703 FLOYD CURL DR', 'StreetAddress2': None, 'CountryName': 'United States', 'StateName': 'Texas', 'StateCode': 'TX', 'CONGRESSDISTRICT': '20', 'CONGRESS_DISTRICT_ORG': 'TX20', 'ORG_UEI_NUM': 'C3KXNLTAAY98', 'ORG_LGL_BUS_NAME': 'THE UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO', 'ORG_PRNT_UEI_NUM': None}
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{'Code': '119100', 'Text': 'BEHAVIORAL NEUROSCIENCE'}
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