Genetic Regulation of Tissue-Specific Urease Isozymes
{'Code': '08090100', 'Directorate': {'Abbreviation': 'BIO', 'LongName': 'Direct For Biological Sciences'}, 'Division': {'Abbreviation': 'IOS', 'LongName': 'Division Of Integrative Organismal Systems'}}
{'SignBlockName': None, 'PO_EMAI': None, 'PO_PHON': None}
The objective of this proposal is to elucidate the mechanism(s)            underlying the genetic expression of urease in the higher plant,                soybean.  Dr. Polacco will investigate the expression of an embryo-             specific isoenzyme of urease as well as a ubiquitous isoenzyme found in         all tissues but at 1/1000th the level of the embryo-specific urease.            Dr. Polacco will conduct molecular genetic experiments to analyze               mutants defective in the expression of the embryo-specific isoenzyme.           The physical and genetic fine structure maps of the locus that encodes          this isoenzyme will be correlated.  Furthermore, the PI proposes to             isolate mutants in the locus encoding the ubiquitous urease.  Gene              products that encode factors that pleitropically regulate the urease            system will also be genetically defined and characterized.                           This work will provide important information concerning the factors        that regulate tissue-specific gene expression during development.  In           addition, the ability to isolate mutants in the structural loci will            lead to a better understanding of the ureases, their processing and             assembly.
{'FirstName': 'Joseph', 'LastName': 'Polacco', 'PI_MID_INIT': 'C', 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'Joseph C Polacco', 'EmailAddress': 'PolaccoJ@missouri.edu', 'NSF_ID': '000426446', 'StartDate': '09/01/1988', 'EndDate': None, 'RoleCode': 'Principal Investigator'}
{'Name': 'University of Missouri-Columbia', 'CityName': 'COLUMBIA', 'ZipCode': '652113020', 'PhoneNumber': '5738827560', 'StreetAddress': '121 UNIVERSITY HALL', 'StreetAddress2': None, 'CountryName': 'United States', 'StateName': 'Missouri', 'StateCode': 'MO', 'CONGRESSDISTRICT': '04', 'CONGRESS_DISTRICT_ORG': 'MO04', 'ORG_UEI_NUM': 'SZPJL5ZRCLF4', 'ORG_LGL_BUS_NAME': 'UNIVERSITY OF MISSOURI SYSTEM', 'ORG_PRNT_UEI_NUM': None}
{'Name': None, 'CityName': None, 'StateCode': None, 'ZipCode': None, 'StreetAddress': None, 'CountryCode': None, 'CountryName': None, 'StateName': None, 'CountryFlag': None, 'CONGRESSDISTRICT': None, 'CONGRESS_DISTRICT_PERF': '""'}
[{'Code': '1111', 'Text': 'DEVELOPMENTAL SYSTEMS CLUSTER'}, {'Code': '1118', 'Text': 'PLANT FUNGAL & MICROB DEV MECH'}, {'Code': '9145', 'Text': 'SPECIAL PROGRAMS-RESERVE'}]
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