ROW:  Invertebrate/Sulfur Bacteria Symbioses:  Mechanistic  Analysis of Chemoautotrophy Using Isolated Bacteriocytes
{'Code': '06040301', 'Directorate': {'Abbreviation': 'GEO', 'LongName': 'Directorate For Geosciences'}, 'Division': {'Abbreviation': 'OCE', 'LongName': 'Division Of Ocean Sciences'}}
{'SignBlockName': 'Phillip R. Taylor', 'PO_EMAI': None, 'PO_PHON': None}
This research investigates the metabolic interplay between an                   invertebrate host and its symbiotic, sulfur-oxidizing bacteria                  by studying (1) the role of sulfur compounds in maintaining the                 functional symbiosis, (2) the internal defense mechanisms used                  for detoxifying sulfide, and (3) the role of sulfur compounds                   in supporting ATP synthesis, carbon fixation, and cellular                      metabolic rate.  The bivalve host Lucinia floridana harbors                     high densities of chemoautotrophic bacteria in its gill                         tissues, and furthermore, the bacteria are invariably housed in                 one specific typed of eucaryotic cell, the bacteriocyte.  The                   use of isolated bacteriocytes figures prominently in the                        experimental approach, because this cell type represents the                    simplest level of organization at which the symbiosis is                        defined.  Studies of sulfide detoxification will be conducted                   at three levels of biological organization: tissue, isolated                    cells, and isolated organelles.  This multi-level approach                      should allow accurate resolution of the functional                              contributions to chemical defense of all individual components                  and then to integrated these separate mechanisms into a unified                 model for sulfide detoxification in this organism.
[{'FirstName': 'Steven', 'LastName': 'Hand', 'PI_MID_INIT': 'C', 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'Steven C Hand', 'EmailAddress': 'shand@LSU.edu', 'NSF_ID': '000353580', 'StartDate': '07/01/1989', 'EndDate': None, 'RoleCode': 'Co-Principal Investigator'}, {'FirstName': 'Amy', 'LastName': 'Anderson', 'PI_MID_INIT': 'E', 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'Amy E Anderson', 'EmailAddress': 'andersoa@CGRB.ORST.edu', 'NSF_ID': '000456311', 'StartDate': '07/01/1989', 'EndDate': None, 'RoleCode': 'Principal Investigator'}]
{'Name': 'University of Colorado at Boulder', 'CityName': 'Boulder', 'ZipCode': '803090001', 'PhoneNumber': '3034926221', 'StreetAddress': '3100 MARINE ST', 'StreetAddress2': 'STE 481 572 UCB', 'CountryName': 'United States', 'StateName': 'Colorado', 'StateCode': 'CO', 'CONGRESSDISTRICT': '02', 'CONGRESS_DISTRICT_ORG': 'CO02', 'ORG_UEI_NUM': 'SPVKK1RC2MZ3', 'ORG_LGL_BUS_NAME': 'THE REGENTS OF THE UNIVERSITY OF COLORADO', 'ORG_PRNT_UEI_NUM': None}
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[{'Code': '1650', 'Text': 'BIOLOGICAL OCEANOGRAPHY'}, {'Code': '3523', 'Text': None}, {'Code': '9120', 'Text': 'CROSS-DIRECTORATE PROGRAMS'}]
{'url': 'https://www.nsf.gov/awardsearch/download?DownloadFileName=1989&All=true', 'xml': '8900107.xml'}