Hydrophobic Peptide-Lipid Bilayer Interactions
{'Code': '08070400', 'Directorate': {'Abbreviation': 'BIO', 'LongName': 'Direct For Biological Sciences'}, 'Division': {'Abbreviation': 'MCB', 'LongName': 'Div Of Molecular and Cellular Bioscience'}}
{'SignBlockName': 'Arthur Kowalsky', 'PO_EMAI': None, 'PO_PHON': None}
The basic plan of this project is to assemble a complete set                    of thermodynamic and structural data for a well defined set                     of peptides in order to explore specific questions concerning                   the nature of protein/bilayer interactions.  This project is                    expected to lead to a refined view of such interactions and                     to provide information about hydrophobicity scales and their                    application in the assessment of membrane protein structure.                                                                                                    The generally accepted image of membranes is that of a quasi                    two-dimensional solution of hydrophobic protein "solutes"                       partitioned into a lipid bilayer "solvent".  It is important                    to develop a quantitative understanding of the bilayer as a                     solvent for hydrophobic molecules with the goal of describing                   not only interactions of hydrophobic peptides with bilayers                     but eventually the interactions of protein with membranes.***//
[{'FirstName': 'Stephen', 'LastName': 'White', 'PI_MID_INIT': 'H', 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'Stephen H White', 'EmailAddress': 'shwhite@uci.edu', 'NSF_ID': '000415301', 'StartDate': '08/01/1988', 'EndDate': None, 'RoleCode': 'Principal Investigator'}, {'FirstName': 'Russell', 'LastName': 'Jacobs', 'PI_MID_INIT': None, 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'Russell Jacobs', 'EmailAddress': 'rjacobs@caltech.edu', 'NSF_ID': '000366307', 'StartDate': '08/01/1988', 'EndDate': None, 'RoleCode': 'Co-Principal Investigator'}]
{'Name': 'University of California-Irvine', 'CityName': 'IRVINE', 'ZipCode': '926970001', 'PhoneNumber': '9498247295', 'StreetAddress': '160 ALDRICH HALL', 'StreetAddress2': None, 'CountryName': 'United States', 'StateName': 'California', 'StateCode': 'CA', 'CONGRESSDISTRICT': '47', 'CONGRESS_DISTRICT_ORG': 'CA47', 'ORG_UEI_NUM': 'MJC5FCYQTPE6', 'ORG_LGL_BUS_NAME': 'UNIVERSITY OF CALIFORNIA IRVINE', 'ORG_PRNT_UEI_NUM': 'MJC5FCYQTPE6'}
{'Name': None, 'CityName': None, 'StateCode': None, 'ZipCode': None, 'StreetAddress': None, 'CountryCode': None, 'CountryName': None, 'StateName': None, 'CountryFlag': None, 'CONGRESSDISTRICT': None, 'CONGRESS_DISTRICT_PERF': '""'}
{'Code': '114400', 'Text': 'Molecular Biophysics'}
{'url': 'https://www.nsf.gov/awardsearch/download?DownloadFileName=1988&All=true', 'xml': '8807431.xml'}