Presidential Young Investigator Award:  Construction and    Characterization of Fusion Proteins
{'Code': '07020000', 'Directorate': {'Abbreviation': 'ENG', 'LongName': 'Directorate For Engineering'}, 'Division': {'Abbreviation': 'CBET', 'LongName': 'Div Of Chem, Bioeng, Env, & Transp Sys'}}
{'SignBlockName': 'Fred G. Heineken', 'PO_EMAI': None, 'PO_PHON': None}
Narrative: This award supports a Presidential Young Investigator                (PYI) to study a variety of Biochemical Engineering problems.  A                major thrust will be made to develop genetically engineered proteins            with improved physical and catalytic characteristics.                                                                                                           Enhanced thermostability of industrially important enzymes will be              generated using in vitro techniques, such as site specific                      mutagenesis and by chemical mutagenesis followed by cloning into                thermophilic bacterium and selection of mutants that synthesize                 temperature tolerant derivatives of the original protein.  Also,                economical protein recovery schemes will be sought through the                  construction of gene fusions of the target gene to synthetic                    oligonucleotides coding for sequences that confer properties which              can be exploited for efficient recovery of bioproducts.                                                                                                         Studies will also be performed in optimizing the production of                  recombinant proteins.  This effort should result in new applications            and greater impact of recombinant DNA in chemical processing.
{'FirstName': 'George', 'LastName': 'Georgiou', 'PI_MID_INIT': None, 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'George Georgiou', 'EmailAddress': 'ggmjd@mail.utexas.edu', 'NSF_ID': '000188352', 'StartDate': '07/01/1987', 'EndDate': None, 'RoleCode': 'Principal Investigator'}
{'Name': 'University of Texas at Austin', 'CityName': 'AUSTIN', 'ZipCode': '787121139', 'PhoneNumber': '5124716424', 'StreetAddress': '110 INNER CAMPUS DR', 'StreetAddress2': None, 'CountryName': 'United States', 'StateName': 'Texas', 'StateCode': 'TX', 'CONGRESSDISTRICT': '25', 'CONGRESS_DISTRICT_ORG': 'TX25', 'ORG_UEI_NUM': 'V6AFQPN18437', 'ORG_LGL_BUS_NAME': 'UNIVERSITY OF TEXAS AT AUSTIN', 'ORG_PRNT_UEI_NUM': None}
{'Name': None, 'CityName': None, 'StateCode': None, 'ZipCode': None, 'StreetAddress': None, 'CountryCode': None, 'CountryName': None, 'StateName': None, 'CountryFlag': None, 'CONGRESSDISTRICT': None, 'CONGRESS_DISTRICT_PERF': '""'}
{'Code': '140200', 'Text': 'BIOCHEMICAL & BIOMASS ENG'}
{'url': 'https://www.nsf.gov/awardsearch/download?DownloadFileName=1986&All=true', 'xml': '8657471.xml'}