Major Shared Equipment for Protein Design and               Characterization
{'Code': '08000000', 'Directorate': {'Abbreviation': 'BIO', 'LongName': 'Direct For Biological Sciences'}, 'Division': {'Abbreviation': 'BIO', 'LongName': 'Direct For Biological Sciences'}}
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This Biological Facilities Center proposal requests funds for the               purchase of ancillary protein sequencing equipment, peptide                     synthesis and purification equipment, and equipment for x-ray                   structure determination of native and engineered proteins.  The                 equipment will be shared by the staff of the Institute of                       Molecular Biology, one of the leading centers for the study of                  macromolecular structure and function, and its subsidiary program               in Cell Biology.  The equipment will be used to identify and/or                 study proteins involved in the mechanism and control of DNA                     replication and transcription, the effect of changes in primary                 structure on stability and tertiary protein structure, the                      interaction of subunits within protein complexes and between                    membrane proteins and lipids, the export of proteins by                         eukaryotic cells, and the mechanism of signal transduction in                   bacterial chemotaxis.  This instrumentation will facilitate the                 collaborative research that has resulted in important scientific                contributions in areas such as the stability of proteins,                       protein-DNA interactions, DNA replication and DNA transcription.
[{'FirstName': 'Peter', 'LastName': 'von Hippel', 'PI_MID_INIT': 'H', 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'Peter H von Hippel', 'EmailAddress': 'petevh@molbio.uoregon.edu', 'NSF_ID': '000087368', 'StartDate': '09/15/1987', 'EndDate': None, 'RoleCode': 'Co-Principal Investigator'}, {'FirstName': 'Brian', 'LastName': 'Matthews', 'PI_MID_INIT': 'W', 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'Brian W Matthews', 'EmailAddress': None, 'NSF_ID': '000234579', 'StartDate': '09/15/1987', 'EndDate': None, 'RoleCode': 'Co-Principal Investigator'}, {'FirstName': 'Frederick', 'LastName': 'Dahlquist', 'PI_MID_INIT': 'W', 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'Frederick W Dahlquist', 'EmailAddress': 'dahlquist@chem.ucsb.edu', 'NSF_ID': '000302440', 'StartDate': '09/15/1987', 'EndDate': None, 'RoleCode': 'Co-Principal Investigator'}, {'FirstName': 'Margaret', 'LastName': 'Lindorfer', 'PI_MID_INIT': 'A', 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'Margaret A Lindorfer', 'EmailAddress': None, 'NSF_ID': '000379817', 'StartDate': '09/15/1987', 'EndDate': None, 'RoleCode': 'Principal Investigator'}, {'FirstName': 'Roderick', 'LastName': 'Capaldi', 'PI_MID_INIT': 'A', 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'Roderick A Capaldi', 'EmailAddress': '503-686-4526', 'NSF_ID': '000337453', 'StartDate': '09/15/1987', 'EndDate': None, 'RoleCode': 'Co-Principal Investigator'}]
{'Name': 'University of Oregon Eugene', 'CityName': 'EUGENE', 'ZipCode': '974031905', 'PhoneNumber': '5413465131', 'StreetAddress': '1776 E 13TH AVE', 'StreetAddress2': None, 'CountryName': 'United States', 'StateName': 'Oregon', 'StateCode': 'OR', 'CONGRESSDISTRICT': '04', 'CONGRESS_DISTRICT_ORG': 'OR04', 'ORG_UEI_NUM': 'Z3FGN9MF92U2', 'ORG_LGL_BUS_NAME': 'UNIVERSITY OF OREGON', 'ORG_PRNT_UEI_NUM': 'Z3FGN9MF92U2'}
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[{'Code': '1112', 'Text': 'Genetic Mechanisms'}, {'Code': '1116', 'Text': 'EUKARYOTIC GENETICS'}]
{'url': 'https://www.nsf.gov/awardsearch/download?DownloadFileName=1987&All=true', 'xml': '8714102.xml'}