U.S.-Venezuela Cooperative Science:  Anaplasma Marginale    Proteins and Attachment to Bovine Red Cell Ligands
{'Code': '01090000', 'Directorate': {'Abbreviation': 'O/D', 'LongName': 'Office Of The Director'}, 'Division': {'Abbreviation': 'OISE', 'LongName': 'Office Of Internatl Science &Engineering'}}
{'SignBlockName': 'Harold Stolberg', 'PO_EMAI': None, 'PO_PHON': None}
This award will support collaborative research between                          Prof. Roger Laine and Prof. Marta Ysern-Caldenty of the Universidad             Simon Bolivar in Caracas, Venezuela.  The objective of the research             is to study the cell surface proteins of Anaplasma marginale, a                 micro-organism that binds to bovine red cells with an end result                similar to the invasion of red cells by malarial protozoans.  The               investigators plan to study the molecular entities that interact at             the cell surfaces of these micro-organisms with bovine erythrocytes,            to form a recognition and binding pair.  Preliminary evidence                   indicates that this binding pair consists of a complex carbohydrate             in the blood cell and a binding protein on the Anaplasma.  This work            will serve to further elucidate the mechanisms behind these binding             interactions.                                                                                                                                                   The Venezuelan side will contribute expertise in the biological                 system under study while the U.S. side brings to bear their                     experience with chemical structural analysis.  Because Anaplasma                marginale has a similar relation to bovine red blood cells as malaria           does to human red cells, the techniques used and knowledge gained in            surface chemistry studies using bovine red blood cells should prove             beneficial to research in both areas.
{'FirstName': 'Roger', 'LastName': 'Laine', 'PI_MID_INIT': 'A', 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'Roger A Laine', 'EmailAddress': 'rlaine@lsu.edu', 'NSF_ID': '000384358', 'StartDate': '03/01/1988', 'EndDate': None, 'RoleCode': 'Principal Investigator'}
{'Name': 'Louisiana State University', 'CityName': 'BATON ROUGE', 'ZipCode': '708030001', 'PhoneNumber': '2255782760', 'StreetAddress': '202 HIMES HALL', 'StreetAddress2': None, 'CountryName': 'United States', 'StateName': 'Louisiana', 'StateCode': 'LA', 'CONGRESSDISTRICT': '06', 'CONGRESS_DISTRICT_ORG': 'LA06', 'ORG_UEI_NUM': 'ECQEYCHRNKJ4', 'ORG_LGL_BUS_NAME': 'LOUISIANA STATE UNIVERSITY', 'ORG_PRNT_UEI_NUM': None}
{'Name': None, 'CityName': None, 'StateCode': None, 'ZipCode': None, 'StreetAddress': None, 'CountryCode': None, 'CountryName': None, 'StateName': None, 'CountryFlag': None, 'CONGRESSDISTRICT': None, 'CONGRESS_DISTRICT_PERF': '""'}
{'Code': '5945', 'Text': 'VENEZUELA'}
{'url': 'https://www.nsf.gov/awardsearch/download?DownloadFileName=1987&All=true', 'xml': '8715765.xml'}