Investigation of Growth in Mixed Substrate Bacterial        Cultures
{'Code': '07020000', 'Directorate': {'Abbreviation': 'ENG', 'LongName': 'Directorate For Engineering'}, 'Division': {'Abbreviation': 'CBET', 'LongName': 'Div Of Chem, Bioeng, Env, & Transp Sys'}}
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This effort will attempt to develop mathematical models to describe the         kinetics in bioreactors in which the nutrient media comprises mixed             substrates.  Previous studies have shown that certain                           substrate-mixtures lead to a sequential utilization of substrates in            some order of preference, while others provide for joint (or                    simultaneous) utilization.  In sequential utilization, the preferred            substrate is the one which supports the highest growth rate.  When this         nutrient is exhausted, there follows a period of new growth during              which a new set of enzymes needed for the utilization of the second             nutrient is produced.  This is followed by growth on the second                 nutrient.  In simultaneous utilization the growth rate is some                  intermediate value between the slowest and fastest possible for the             individual nutrient.  The mathematical models will establish an                 optimality condition to describe these phenomena and these models will          be tested using mixed substrates in batch and continuous systems.
{'FirstName': 'Doraiswami', 'LastName': 'Ramkrishna', 'PI_MID_INIT': None, 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'Doraiswami Ramkrishna', 'EmailAddress': 'ramkrish@ecn.purdue.edu', 'NSF_ID': '000384443', 'StartDate': '08/15/1986', 'EndDate': None, 'RoleCode': 'Principal Investigator'}
{'Name': 'Purdue University', 'CityName': 'WEST LAFAYETTE', 'ZipCode': '479061332', 'PhoneNumber': '7654941055', 'StreetAddress': '2550 NORTHWESTERN AVE # 1100', 'StreetAddress2': None, 'CountryName': 'United States', 'StateName': 'Indiana', 'StateCode': 'IN', 'CONGRESSDISTRICT': '04', 'CONGRESS_DISTRICT_ORG': 'IN04', 'ORG_UEI_NUM': 'YRXVL4JYCEF5', 'ORG_LGL_BUS_NAME': 'PURDUE UNIVERSITY', 'ORG_PRNT_UEI_NUM': 'YRXVL4JYCEF5'}
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[{'Code': '1402', 'Text': 'BIOCHEMICAL & BIOMASS ENG'}, {'Code': '9120', 'Text': 'CROSS-DIRECTORATE PROGRAMS'}]
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