Bioreactor Development for the Induction, Proliferation, andUse of Structurally Differentiated Plant Tissue Culture for Secondary Metabolite Production
{'Code': '07020000', 'Directorate': {'LongName': 'Directorate For Engineering'}, 'Division': {'LongName': 'Div Of Chem, Bioeng, Env, & Transp Sys'}}
{'SignBlockName': 'Fred G. Heineken'}
This proposal seeks to test whether secondary metabolite                        production can be increased through:                                                                                                                                - the development of an understanding of the effects of                           immobilization on biochemical and structural differentiation                    in plant cells, and                                                                                                                                           - the study of reactor design and operation for the growth and                    the effective use of organ tissues for the production of                        secondary metabolites.                                                                                                                                    Results from the current project suggest that immobilization can                result in a significant increase in biochemical and structural                  differentiation.  The PIs plan to test the role that mass transfer              gradients, cell matrix interactions, and cellular association play              in such responses.
[{'FirstName': 'Michael', 'LastName': 'Shuler', 'EmailAddress': 'mls50@cornell.edu', 'StartDate': '08/01/1988', 'EndDate': None, 'RoleCode': 'Principal Investigator'}, {'FirstName': 'Elizabeth', 'LastName': 'Earle', 'EmailAddress': 'ede3@cornell.edu', 'StartDate': '08/01/1988', 'EndDate': None, 'RoleCode': 'Co-Principal Investigator'}]
{'Name': 'Cornell University', 'CityName': 'Ithaca', 'ZipCode': '148502820', 'PhoneNumber': '6072555014', 'StreetAddress': '373 Pine Tree Road', 'CountryName': 'United States', 'StateName': 'New York', 'StateCode': 'NY'}
{'Code': '1491', 'Text': 'Cellular & Biochem Engineering'}
{'url': 'https://www.nsf.gov/awardsearch/download?DownloadFileName=1988&All=true', 'xml': '8801492.xml'}