Analytical Studies of Binding Protein Interactions with     Enzyme-Ligand Conjugates
{'Code': '03090006', 'Directorate': {'Abbreviation': 'MPS', 'LongName': 'Direct For Mathematical & Physical Scien'}, 'Division': {'Abbreviation': 'CHE', 'LongName': 'Division Of Chemistry'}}
{'SignBlockName': 'Henry N. Blount, III', 'PO_EMAI': None, 'PO_PHON': None}
This project is in the general area of Analytical and Surface                   Chemistry and in the subfield of bioanalytical chemistry. The                   studies planned here focus on three related areas of research.                  These three areas include 1) developing analytical procedures                   for selected proteins and herbicides using simple homogeneous                   methodology, 2) the use of hollow dialysis fibers to develop a                  continuous and reversible biomolecule detection scheme, 3)                      fundamental experiments designed to select monoclonal                           anti-ligand antibodies with desirable binding characteristics                   but little or no bridging group recognition.                                                                                                                    The studies planned here are designed to develop assays based                   on the selective interactions of certain proteins. These assays                 should be almost as selective, but much less expensive than                     assays based on the use of antibodies. In addition, this new                    methodology should not require the use of radioactive labels.
{'FirstName': 'Mark', 'LastName': 'Meyerhoff', 'PI_MID_INIT': None, 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'Mark Meyerhoff', 'EmailAddress': 'mmeyerho@umich.edu', 'NSF_ID': '000178832', 'StartDate': '12/15/1988', 'EndDate': None, 'RoleCode': 'Principal Investigator'}
{'Name': 'Regents of the University of Michigan - Ann Arbor', 'CityName': 'ANN ARBOR', 'ZipCode': '481091079', 'PhoneNumber': '7347636438', 'StreetAddress': '1109 GEDDES AVE, SUITE 3300', 'StreetAddress2': None, 'CountryName': 'United States', 'StateName': 'Michigan', 'StateCode': 'MI', 'CONGRESSDISTRICT': '06', 'CONGRESS_DISTRICT_ORG': 'MI06', 'ORG_UEI_NUM': 'GNJ7BBP73WE9', 'ORG_LGL_BUS_NAME': 'REGENTS OF THE UNIVERSITY OF MICHIGAN', 'ORG_PRNT_UEI_NUM': None}
{'Name': None, 'CityName': None, 'StateCode': None, 'ZipCode': None, 'StreetAddress': None, 'CountryCode': None, 'CountryName': None, 'StateName': None, 'CountryFlag': None, 'CONGRESSDISTRICT': None, 'CONGRESS_DISTRICT_PERF': '""'}
{'Code': '1974', 'Text': 'ANALYTICAL SEPARATIONS & MEAS.'}
{'url': 'https://www.nsf.gov/awardsearch/download?DownloadFileName=1988&All=true', 'xml': '8813952.xml'}