Mechanisms of Bacterial Toxin-Plant Membrane Interactions
{'Code': '08070400', 'Directorate': {'Abbreviation': 'BIO', 'LongName': 'Direct For Biological Sciences'}, 'Division': {'Abbreviation': 'MCB', 'LongName': 'Div Of Molecular and Cellular Bioscience'}}
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Mechanisms of Bacterial Toxin Plant Membrane Interactions:                           Studies on the mode of action of the Pseudomonas syringae pv               syringae phytotoxin, syringomycin, on plant cell membranes are                  proposed.  Previous studies have shown that syringomycin has a                  primary effect on the plasma membrane of susceptible cells.                     Experiments are described for determining the role of protein                   phosphorylation in the syringomycin stimulation of the plant                    plasma membrane H+-ATPase, for determining if plasma membrane                   phosphatidylinositol turnover is involved in toxin action, and                  for identifying the syringomycin molecular binding site.                                                                                                             This project is significant because it will elucidate how a                ubiquitous and important bacterial phytotoxin causes plant                      disease and also because it will provide basic information about                the function, structure and regulation of the plant cell plasma                 membrane.
{'FirstName': 'Jon', 'LastName': 'Takemoto', 'PI_MID_INIT': 'Y', 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'Jon Y Takemoto', 'EmailAddress': 'jon@biology.usu.edu', 'NSF_ID': '000451076', 'StartDate': '07/01/1987', 'EndDate': None, 'RoleCode': 'Principal Investigator'}
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[{'Code': '1142', 'Text': 'CELLULAR BIOCHEMISTRY'}, {'Code': '1144', 'Text': 'Molecular Biophysics'}]
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