Conformational Transitions in Polypeptides
{'Code': '08070400', 'Directorate': {'Abbreviation': 'BIO', 'LongName': 'Direct For Biological Sciences'}, 'Division': {'Abbreviation': 'MCB', 'LongName': 'Div Of Molecular and Cellular Bioscience'}}
{'SignBlockName': 'Arthur Kowalsky', 'PO_EMAI': None, 'PO_PHON': None}
A combination of theoretical and experimental methods will be                   used to understand how beta sheets are formed in polypeptide                    chains.  The theoretical portion of the research will                           continue the evolution of Dr. Mattice's recently introduced                     theory of the beta sheet to coil transition.  Fluorescence                      methods will also be developed for study of the sheet to coil                   transition.                                                                                                                                                     Although the structures of alpha helix and beta sheets have                     been known for some time, the current understanding of helix                    formation far surpasses the knowledge of the formation of                       beta sheets.  The theoretical work done by Dr. Mattice                          represents a significant advance in understanding the basic                     physical chemistry of protein denaturation and folding.***
{'FirstName': 'Wayne', 'LastName': 'Mattice', 'PI_MID_INIT': 'L', 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'Wayne L Mattice', 'EmailAddress': 'wlm@polymer.uakron.edu', 'NSF_ID': '000390713', 'StartDate': '07/01/1988', 'EndDate': None, 'RoleCode': 'Principal Investigator'}
{'Name': 'University of Akron', 'CityName': 'AKRON', 'ZipCode': '443250001', 'PhoneNumber': '3309722760', 'StreetAddress': '302 BUCHTEL COMMON', 'StreetAddress2': None, 'CountryName': 'United States', 'StateName': 'Ohio', 'StateCode': 'OH', 'CONGRESSDISTRICT': '13', 'CONGRESS_DISTRICT_ORG': 'OH13', 'ORG_UEI_NUM': 'DFNLDECWM8J8', 'ORG_LGL_BUS_NAME': 'THE UNIVERSITY OF AKRON', 'ORG_PRNT_UEI_NUM': 'DFNLDECWM8J8'}
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{'Code': '114400', 'Text': 'Molecular Biophysics'}
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