Molecular Dynamics in the Mitochondrial Inner Membrane
{'Code': '08070400', 'Directorate': {'Abbreviation': 'BIO', 'LongName': 'Direct For Biological Sciences'}, 'Division': {'Abbreviation': 'MCB', 'LongName': 'Div Of Molecular and Cellular Bioscience'}}
{'SignBlockName': 'Kamal Shukla', 'PO_EMAI': None, 'PO_PHON': None}
Dr. Hackenbrock plans to expand his biophysical studies on                      the relationship between diffusion-based collisional                            interactions and electron transport activities of the redox                     components in the inner membrane of the mitochondrion.                          Results reveal that diffusion-based collisions between all                      redox partners occur with frequencies sufficient to account                     for the maximum rate of their electron transfers.  Dr.                          Hackenbrock intends to investigate the role of diffusion of                     the redox components in the control of the rate of maximum                      and coupled electron transport.  A combination of highly                        technical biophysical approaches will be used including,                        fluorescence recovery after photobleaching, fluorescence                        polarization, resonance energy transfer, total internal                         reflection fluorescence and digitized video and nanovid                         microscopy.                                                                                                                                                     The transfer of electrons in membranes is preceded by random,                   diffusion-based collisions between all redox partners in a                      highly fluid membrane environment.  All redox components are                    highly mobile diffusants and suggest that such diffusion is                     rate limiting for maximum electron transport.***//
{'FirstName': 'Charles', 'LastName': 'Hackenbrock', 'PI_MID_INIT': 'R', 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'Charles R Hackenbrock', 'EmailAddress': None, 'NSF_ID': '000151176', 'StartDate': '10/15/1993', 'EndDate': None, 'RoleCode': 'Principal Investigator'}
{'Name': 'University of North Carolina at Chapel Hill', 'CityName': 'CHAPEL HILL', 'ZipCode': '275995023', 'PhoneNumber': '9199663411', 'StreetAddress': '104 AIRPORT DR STE 2200', 'StreetAddress2': None, 'CountryName': 'United States', 'StateName': 'North Carolina', 'StateCode': 'NC', 'CONGRESSDISTRICT': '04', 'CONGRESS_DISTRICT_ORG': 'NC04', 'ORG_UEI_NUM': 'D3LHU66KBLD5', 'ORG_LGL_BUS_NAME': 'UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL', 'ORG_PRNT_UEI_NUM': 'N8DMK1K4C2K5'}
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{'Code': '1164', 'Text': 'MOLECULAR BIOPHYSICS'}
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