A Systematic Study of Affinity Partitioning Systems
{'Code': '07020000', 'Directorate': {'Abbreviation': 'ENG', 'LongName': 'Directorate For Engineering'}, 'Division': {'Abbreviation': 'CBET', 'LongName': 'Div Of Chem, Bioeng, Env, & Transp Sys'}}
{'SignBlockName': 'Jeffrey Foltz', 'PO_EMAI': 'jfoltz@nsf.gov', 'PO_PHON': '7032924231'}
A thermodynamic model for equilibrium affinity partitioning will                be developed and tested experimentally.  Critical experiments                   have been carefully devised to test the model for the first time                in the ideal case with 1:1 binding interaction and minimal charge               effect present.  The evaluated model will facilitate study of the               interdependence of charge and affinity effects and allow                        determination of the effective number of binding sites in more                  general cases.                                                                                                                                                  A secondary objective of this project is to optimize the                        isolation of industrially important antibiotics using the                       proposed model.  The result of the research could lead to a                     simple model which could be used for the development of new                     affinity partitioning processes for large scale separation and                  purification of biomolecules.
{'FirstName': 'William', 'LastName': 'Clark', 'PI_MID_INIT': 'M', 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'William M Clark', 'EmailAddress': 'wmclark@wpi.edu', 'NSF_ID': '000257307', 'StartDate': '03/01/1988', 'EndDate': None, 'RoleCode': 'Principal Investigator'}
{'Name': 'Worcester Polytechnic Institute', 'CityName': 'WORCESTER', 'ZipCode': '016092247', 'PhoneNumber': '5088315000', 'StreetAddress': '100 INSTITUTE RD', 'StreetAddress2': None, 'CountryName': 'United States', 'StateName': 'Massachusetts', 'StateCode': 'MA', 'CONGRESSDISTRICT': '02', 'CONGRESS_DISTRICT_ORG': 'MA02', 'ORG_UEI_NUM': 'HJNQME41NBU4', 'ORG_LGL_BUS_NAME': 'WORCESTER POLYTECHNIC INSTITUTE', 'ORG_PRNT_UEI_NUM': None}
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{'Code': '1417', 'Text': 'Interfacial Engineering Progra'}
{'url': 'https://www.nsf.gov/awardsearch/download?DownloadFileName=1987&All=true', 'xml': '8722741.xml'}