Development of Methods in Fiber Diffraction Analysis of     Macromolecules
{'Code': '08000000', 'Directorate': {'Abbreviation': 'BIO', 'LongName': 'Direct For Biological Sciences'}, 'Division': {'Abbreviation': 'BIO', 'LongName': 'Direct For Biological Sciences'}}
{'SignBlockName': 'Machi F. Dilworth', 'PO_EMAI': None, 'PO_PHON': None}
Many macro molecules give rise to diffraction patterns when                     exposed to X-rays.  Previously, these patterns were of use in                   determining molecular structure of molecules which contain small,               repeating portions or else the analysis was limited to very low                 resolution.  Over the lst l5 years, the principal investigator                  has developed methods of X-ray diffraction analysis (called fiber               diffraction analysis) which have determined the molecular                       structure of the Tobacco Mosaic Virus (TMVB) at a resolution of                 2.9 angstroms.  The present proposal is to develop methods to                   extend the techniques utilized in the TMV study to other                        biological systems.  Methodology will be developed using other                  viruses, cytoskeletal filaments and nucleoprotein complexes.
{'FirstName': 'Gerald', 'LastName': 'Stubbs', 'PI_MID_INIT': None, 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'Gerald Stubbs', 'EmailAddress': 'gerald.stubbs@vanderbilt.edu', 'NSF_ID': '000090013', 'StartDate': '02/15/1988', 'EndDate': None, 'RoleCode': 'Principal Investigator'}
{'Name': 'Vanderbilt University', 'CityName': 'NASHVILLE', 'ZipCode': '372032416', 'PhoneNumber': '6153222631', 'StreetAddress': '110 21ST AVE S', 'StreetAddress2': None, 'CountryName': 'United States', 'StateName': 'Tennessee', 'StateCode': 'TN', 'CONGRESSDISTRICT': '05', 'CONGRESS_DISTRICT_ORG': 'TN05', 'ORG_UEI_NUM': 'GTNBNWXJ12D5', 'ORG_LGL_BUS_NAME': 'VANDERBILT UNIVERSITY', 'ORG_PRNT_UEI_NUM': None}
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{'Code': '1108', 'Text': 'INSTRUMENTAT & INSTRUMENT DEVP'}
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