Structural Requirements for Protein Membrane Assembly
{'Code': '08070600', 'Directorate': {'Abbreviation': 'BIO', 'LongName': 'Direct For Biological Sciences'}, 'Division': {'Abbreviation': 'MCB', 'LongName': 'Div Of Molecular and Cellular Bioscience'}}
{'SignBlockName': 'Maryanna P. Henkart', 'PO_EMAI': None, 'PO_PHON': None}
This is a proposal to explore in detail leader peptidase, an               integral transmembrane protein, to determine the exact                          requirements for membrane insertion and translocation of the c-                 terminal domain of this enzyme onto the outside of the                          Eescheria coli inner membrane.  Site-directed mutagenesis and                   gene cloning techniques will be used to define and characterize                 the assembly elements within membrane proteins.  The study will                 contribute to a better understanding of protein targeting and                   membrane assembly in cells and ultimately, might the help                       understand molecular basis of many diseases.
{'FirstName': 'Ross', 'LastName': 'Dalbey', 'PI_MID_INIT': 'E', 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'Ross E Dalbey', 'EmailAddress': 'dalbey@chemistry.ohio-state.edu', 'PI_PHON': '6142922384', 'NSF_ID': '000466485', 'StartDate': '06/01/1988', 'EndDate': None, 'RoleCode': 'Principal Investigator'}
{'Name': 'Ohio State University Research Foundation -DO NOT USE', 'CityName': 'Columbus', 'ZipCode': '432101016', 'PhoneNumber': '6146888734', 'StreetAddress': '1960 KENNY RD', 'StreetAddress2': None, 'CountryName': 'United States', 'StateName': 'Ohio', 'StateCode': 'OH', 'CONGRESSDISTRICT': '03', 'CONGRESS_DISTRICT_ORG': 'OH03', 'ORG_UEI_NUM': 'QR7NH79713E5', 'ORG_LGL_BUS_NAME': None, 'ORG_PRNT_UEI_NUM': None}
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{'Code': '1114', 'Text': 'Cellular Dynamics and Function'}
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