X-Ray Source and Detector for Protein Crystallography
{'Code': '08080102', 'Directorate': {'LongName': 'Direct For Biological Sciences'}, 'Division': {'LongName': 'Div Of Biological Infrastructure'}}
{'SignBlockName': 'Kathie L. Olsen'}
Protein crystallography is playing a central role in the advances               made in biochemical research today.  This application proposes to               set up a state-of-the-art laboratory-based data collection                      facility, consisting of a rotating anode source with a position-                sensitive area detector.  This facility would complement the                    existing facility for macromolecular crystallography at the                     Biomedical Technology Resource at the Cornell High Energy                       Synchrotron Source (MacCHESS).  The current interests and                       projects for which the new data collection facility would be used               cover diverse biochemical areas.  These include structure studies               of physiologically important molecules such as calcium binding                  proteins and hormones, enzymes, such as farnesyl pyrophosphate                  synthetase, which catalyze reactions in the biosynthetic pathways               of some unusual and interesting natural products, FAD-containing                redox enzymes, bacteriophage proteins which regulate gene                       transcription, specifically mutated or chemically modified                      species of RNAse, and in the future, systems involving membrane                 proteins currently under study.
[{'FirstName': 'John', 'LastName': 'Moffat', 'EmailAddress': 'moffat@cars.uchicago.edu', 'StartDate': '05/01/1989', 'EndDate': None, 'RoleCode': 'Co-Principal Investigator'}, {'FirstName': 'Jon', 'LastName': 'Clardy', 'EmailAddress': 'jcc12@cornell.edu', 'StartDate': '05/01/1989', 'EndDate': None, 'RoleCode': 'Co-Principal Investigator'}, {'FirstName': 'Paul', 'LastName': 'Karplus', 'EmailAddress': 'karplusp@science.oregonstate.edu', 'StartDate': '05/01/1989', 'EndDate': None, 'RoleCode': 'Principal Investigator'}]
{'Name': 'Cornell University', 'CityName': 'Ithaca', 'ZipCode': '148502820', 'PhoneNumber': '6072555014', 'StreetAddress': '373 Pine Tree Road', 'CountryName': 'United States', 'StateName': 'New York', 'StateCode': 'NY'}
{'Code': '1108', 'Text': 'INSTRUMENTAT & INSTRUMENT DEVP'}
{'url': 'https://www.nsf.gov/awardsearch/download?DownloadFileName=1988&All=true', 'xml': '8820910.xml'}