Biological Control of Fungal Plant Pathogens
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{'SignBlockName': 'Ritchie B. Coryell', 'PO_EMAI': None, 'PO_PHON': None}
A strain of Pseudomonas fluorescens has been developed which                    shows inhibition of Pythium ultimum,  Fusarium, Thielaviopsis                   basicola and other pathogenic fungi by producing a novel                        antibiotic, fusaromycin A.  Both P. ultimum and T. basucika                     are important components of the seedling disease complex of                     cotton.  The goal of this proposal is to understand the                         genetic and biochemical basis of this inhibition as a means                     to developing an improved microbial fungicide for this crop.                    The immediate objective is to isolate the genomic regions                       which carry the antibiotic biosynthetic genes by                                complementation with chemical mutants which have lost fungal                    inhibition activity.  This will permit the assessment of the                    level of genetic complexity of the biosynthetic pathway.                                                                                                        The research will open the way to the development of improved                   bacterial fungicides to control soil-borne fungi pathogenic                     to plants.
{'FirstName': 'William', 'LastName': 'Tucker', 'PI_MID_INIT': 'T', 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'William T Tucker', 'EmailAddress': None, 'PI_PHON': None, 'NSF_ID': '000458448', 'StartDate': '01/01/1989', 'EndDate': None, 'RoleCode': 'Principal Investigator'}
{'Name': 'DNA Plant Technologies, Inc.', 'CityName': 'Oakland', 'ZipCode': '946081244', 'PhoneNumber': '5105472395', 'StreetAddress': '6701 San Pablo Avenue', 'StreetAddress2': None, 'CountryName': 'United States', 'StateName': 'California', 'StateCode': 'CA', 'CONGRESSDISTRICT': '13', 'CONGRESS_DISTRICT_ORG': 'CA13', 'ORG_UEI_NUM': None, 'ORG_LGL_BUS_NAME': None, 'ORG_PRNT_UEI_NUM': None}
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{'Code': '5371', 'Text': 'SBIR Phase I'}
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