Assessing and Manipulating Single-Cell Productivity in      Recombinant Cell Populations
{'Code': '07020000', 'Directorate': {'Abbreviation': 'ENG', 'LongName': 'Directorate For Engineering'}, 'Division': {'Abbreviation': 'CBET', 'LongName': 'Div Of Chem, Bioeng, Env, & Transp Sys'}}
{'SignBlockName': 'Fred G. Heineken', 'PO_EMAI': None, 'PO_PHON': None}
This research involves three parallel and conceptually related                  studies to explore the bases for heterogeneity and single-cell                  productivity in recombinant microbial populations.  It also seeks               to develop quantitative understandings of the relationships                     between genetic and environmental parameters and this                           heterogeneity.  The research involves very recent developments in               experimental methodology for rapid single-cell measurements and                 will contribute to further expansion and broader application of                 these extremely efficient and informative measurements.                                                                                                         E. coli and yeast cells will also be studied using a set of                     experimental systems which have been developed recently in the                  biotechnology industry.  Three graduate students will conduct the               proposed experiments and will be in direct collaboration with a                 local biotechnology company.
{'FirstName': 'James', 'LastName': 'Bailey', 'PI_MID_INIT': 'E', 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'James E Bailey', 'EmailAddress': None, 'NSF_ID': '000294982', 'StartDate': '07/01/1988', 'EndDate': None, 'RoleCode': 'Principal Investigator'}
{'Name': 'California Institute of Technology', 'CityName': 'PASADENA', 'ZipCode': '911250001', 'PhoneNumber': '6263956219', 'StreetAddress': '1200 E CALIFORNIA BLVD', 'StreetAddress2': None, 'CountryName': 'United States', 'StateName': 'California', 'StateCode': 'CA', 'CONGRESSDISTRICT': '28', 'CONGRESS_DISTRICT_ORG': 'CA28', 'ORG_UEI_NUM': 'U2JMKHNS5TG4', 'ORG_LGL_BUS_NAME': 'CALIFORNIA INSTITUTE OF TECHNOLOGY', 'ORG_PRNT_UEI_NUM': None}
{'Name': None, 'CityName': None, 'StateCode': None, 'ZipCode': None, 'StreetAddress': None, 'CountryCode': None, 'CountryName': None, 'StateName': None, 'CountryFlag': None, 'CONGRESSDISTRICT': None, 'CONGRESS_DISTRICT_PERF': '""'}
{'Code': '1491', 'Text': 'Cellular & Biochem Engineering'}
{'url': 'https://www.nsf.gov/awardsearch/download?DownloadFileName=1988&All=true', 'xml': '8805636.xml'}