Synthetic and Postsynthetic Changes in Histones of Alfalfa  in Adaptation to Salt Tolerance
{'Code': '08070600', 'Directorate': {'Abbreviation': 'BIO', 'LongName': 'Direct For Biological Sciences'}, 'Division': {'Abbreviation': 'MCB', 'LongName': 'Div Of Molecular and Cellular Bioscience'}}
{'SignBlockName': 'Maryanna P. Henkart', 'PO_EMAI': None, 'PO_PHON': None}
This is a proposal to characterize a protein, histone from                 nuclear chromatin of the alfalfa plant.  Because the structure                  and function of chromatin is highly dependant on the                            intracellular environment, plant chromatin may be significantly                 affected by salts in plants grown under saline conditions.                      Alfalfa contains multiple histone variants and high levels of                   histone acetylation, depending on growth conditions.  Cellular,                 biochemical and molecular techniques will be used to characterize               the histones.  These studies, which have been few in plants, will               significantly increase our knowledge of plant histone variants                  and postsynthetic modifications.  A good characterization of                    histones should contribute to our understanding of the proteins'                role in providing dynamic balance for a stable packaging of DNA,                for interaction sites with regulatory components and for the                    localized and selective unpacking of gene sequences for                         transcription.
{'FirstName': 'Jakob', 'LastName': 'Waterborg', 'PI_MID_INIT': 'H', 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'Jakob H Waterborg', 'EmailAddress': 'WaterborgJ@umkc.edu', 'NSF_ID': '000467091', 'StartDate': '05/01/1988', 'EndDate': None, 'RoleCode': 'Principal Investigator'}
{'Name': 'Board of Regents, NSHE, obo University of Nevada, Reno', 'CityName': 'RENO', 'ZipCode': '895570001', 'PhoneNumber': '7757844040', 'StreetAddress': '1664 N VIRGINIA ST # 285', 'StreetAddress2': None, 'CountryName': 'United States', 'StateName': 'Nevada', 'StateCode': 'NV', 'CONGRESSDISTRICT': '02', 'CONGRESS_DISTRICT_ORG': 'NV02', 'ORG_UEI_NUM': 'WLDGTNCFFJZ3', 'ORG_LGL_BUS_NAME': 'BOARD OF REGENTS OF THE NEVADA SYSTEM OF HIGHER ED', 'ORG_PRNT_UEI_NUM': 'WLDGTNCFFJZ3'}
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{'Code': '1114', 'Text': 'Cellular Dynamics and Function'}
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