Development of Separation and Purification Processes:       Chromatographic Scale-Up
{'Code': '07020000', 'Directorate': {'Abbreviation': 'ENG', 'LongName': 'Directorate For Engineering'}, 'Division': {'Abbreviation': 'CBET', 'LongName': 'Div Of Chem, Bioeng, Env, & Transp Sys'}}
{'SignBlockName': 'Fred G. Heineken', 'PO_EMAI': None, 'PO_PHON': None}
Production of high volume biologically active compounds imortant in             animal health, food processing, and human health require large                  bioractor ovolumes.  Consequently, scale-up of downstream processing            steps become an increasingly important factor.  Examples include                insulin, human and animal growth hormones, and selected classes of              antibiotics.  Key areas in bioseparations include adsorptive and                chromatiographic separations and these form the focus of this research.         Fundamental data bases and scale-up protocols for adsorptive and                chromatographic purification of fermentation-derived molecules are              generally lacking relative to other bioseparation processes.  The goal          of this research program is to expand the knowledge base of process             chromatography and adsorption to promote its use on a large scale.
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{'Code': '1491', 'Text': 'Cellular & Biochem Engineering'}
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