Structure-Function Studies of L-3-Hydorxyacyl Coenzyme A    Dehydrogenase, Fumarase and Cytoplasmic Malate Dehydrogenase
{'Code': '08070400', 'Directorate': {'Abbreviation': 'BIO', 'LongName': 'Direct For Biological Sciences'}, 'Division': {'Abbreviation': 'MCB', 'LongName': 'Div Of Molecular and Cellular Bioscience'}}
{'SignBlockName': 'Arthur Kowalsky', 'PO_EMAI': None, 'PO_PHON': None}
For the understanding of the biochemical phenomena of enzyme                    activity data at the molecular level is one of the most vital                   needs.  Dr. Banaszak is performing an X-ray crystallographic                    study of L-3 hydroxyacyl CoA Dehydrogenase (BHDH),                              cytoplasmic malate dehydrogenase (sMDH) and fumarase.                           Although these structural studies are at different stages,                      the long range objectives in each case are similar.                             Structural investigations of the type proposed are                              fundamental to understanding the mechanism of catalytic                         activity these enzymes which carry out essential steps in a                     number of fundamental biochemical pathways.
{'FirstName': 'Leonard', 'LastName': 'Banaszak', 'PI_MID_INIT': 'J', 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'Leonard J Banaszak', 'EmailAddress': 'len_b@dcmir.med.umn.edu', 'NSF_ID': '000340543', 'StartDate': '12/01/1987', 'EndDate': None, 'RoleCode': 'Principal Investigator'}
{'Name': 'Washington University School of Medicine', 'CityName': 'SAINT LOUIS', 'ZipCode': '63110', 'PhoneNumber': '3147474134', 'StreetAddress': 'ONE BROOKINGS DR', 'StreetAddress2': None, 'CountryName': 'United States', 'StateName': 'Missouri', 'StateCode': 'MO', 'CONGRESSDISTRICT': '01', 'CONGRESS_DISTRICT_ORG': 'MO01', 'ORG_UEI_NUM': 'L6NFUM28LQM5', 'ORG_LGL_BUS_NAME': 'WASHINGTON UNIVERSITY, THE', 'ORG_PRNT_UEI_NUM': None}
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[{'Code': '1144', 'Text': 'Molecular Biophysics'}, {'Code': '9145', 'Text': 'SPECIAL PROGRAMS-RESERVE'}]
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