U.S.-Japan Cooperative Research: Micromanipulation Study of Mechanisms Controlling Motility in Sperm Flagella
{'Code': '01090000', 'Directorate': {'Abbreviation': 'O/D', 'LongName': 'Office Of The Director'}, 'Division': {'Abbreviation': 'OISE', 'LongName': 'Office Of Internatl Science &Engineering'}}
{'SignBlockName': 'Charles Wallace', 'PO_EMAI': None, 'PO_PHON': None}
This award will enable collaborative research between Drs. Ian R.               Gibbons, Barbara H. Gibbons and Dan Eshel of the University of                  Hawaii and Drs. Keiichi Takahashi and Chikako Shingyoji of the                  University of Tokyo, Japan.  They will examine the mechanisms which             regulate the sliding of sperm flagellar microtubules and thereby                produce bending movements.  The investigators propose to use sea                urchin spermatozoa for their studies.  Individual spermatozoa will              be held by suction at the tip of a specially shaped micropipette                and the effects of pipette movements on flagellar waveform will be              analyzed.  Transducers for studying rapid mechanical transients and             software for computer controlled movement of the micropipette will              be developed.                                                                                                                                                   The investigators will be developing a new and potentially powerful             way to analyze the still poorly understood mechanism of ciliary                 motility.  The complementary strengths of the two laboratories will             provide necessary expertise in a wide range of techniques,                      including micromanipulation, protein modification, video                        microscopy, hydrodynamic analysis, and real-time computer                       programming.
{'FirstName': 'Ian', 'LastName': 'Gibbons', 'PI_MID_INIT': 'R', 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'Ian R Gibbons', 'EmailAddress': None, 'NSF_ID': '000225742', 'StartDate': '04/01/1988', 'EndDate': None, 'RoleCode': 'Principal Investigator'}
{'Name': 'University of Hawaii', 'CityName': 'HONOLULU', 'ZipCode': '968222247', 'PhoneNumber': '8089567800', 'StreetAddress': '2425 CAMPUS RD SINCLAIR RM 1', 'StreetAddress2': None, 'CountryName': 'United States', 'StateName': 'Hawaii', 'StateCode': 'HI', 'CONGRESSDISTRICT': '01', 'CONGRESS_DISTRICT_ORG': 'HI01', 'ORG_UEI_NUM': 'NSCKLFSSABF2', 'ORG_LGL_BUS_NAME': 'UNIVERSITY OF HAWAII', 'ORG_PRNT_UEI_NUM': None}
{'Name': None, 'CityName': None, 'StateCode': None, 'ZipCode': None, 'StreetAddress': None, 'CountryCode': None, 'CountryName': None, 'StateName': None, 'CountryFlag': None, 'CONGRESSDISTRICT': None, 'CONGRESS_DISTRICT_PERF': '""'}
{'Code': '5921', 'Text': 'JAPAN'}
{'url': 'https://www.nsf.gov/awardsearch/download?DownloadFileName=1987&All=true', 'xml': '8716302.xml'}