PYI:  Ecology and Genetics of Microbial Evolution
{'Code': '08010207', 'Directorate': {'Abbreviation': 'BIO', 'LongName': 'Direct For Biological Sciences'}, 'Division': {'Abbreviation': 'DEB', 'LongName': 'Division Of Environmental Biology'}}
{'SignBlockName': 'Gregory J. McCants', 'PO_EMAI': None, 'PO_PHON': None}
Funding from the prestigious five-year Presidential Young                       Investigator award will be used to support research on the                      population biology of bacteria and their plasmids.  Their large                 populations and short generations permit an experimental, not                   merely correlative, approach to the study of evolutionary                       processes.  Research efforts will fall into four major areas:                   genetic basis of fitness in evolving populations of Escherichia                 coli, fitness consequences associated with alternative modes of                 regulation of tetracycline resistance genes in E. coli,                         evolution and genetics of an association between E. coli and                    plasmid pACYC184, and effects of recombinant functions                          (particularly chlorobenzoate degradation) on plasmid stability                  and host fitness in Pseudomonas species.  Precise measurements                  of the effects of particular genetic variants, both chromosomal                 and extrachromosomal, on bacterial net growth, or relative                      fitness, are required for these projects.
{'FirstName': 'Richard', 'LastName': 'Lenski', 'PI_MID_INIT': 'E', 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'Richard E Lenski', 'EmailAddress': 'lenski@msu.edu', 'NSF_ID': '000250057', 'StartDate': '07/15/1988', 'EndDate': None, 'RoleCode': 'Principal Investigator'}
{'Name': 'University of California-Irvine', 'CityName': 'IRVINE', 'ZipCode': '926970001', 'PhoneNumber': '9498247295', 'StreetAddress': '160 ALDRICH HALL', 'StreetAddress2': None, 'CountryName': 'United States', 'StateName': 'California', 'StateCode': 'CA', 'CONGRESSDISTRICT': '47', 'CONGRESS_DISTRICT_ORG': 'CA47', 'ORG_UEI_NUM': 'MJC5FCYQTPE6', 'ORG_LGL_BUS_NAME': 'UNIVERSITY OF CALIFORNIA IRVINE', 'ORG_PRNT_UEI_NUM': 'MJC5FCYQTPE6'}
{'Name': None, 'CityName': None, 'StateCode': None, 'ZipCode': None, 'StreetAddress': None, 'CountryCode': None, 'CountryName': None, 'StateName': None, 'CountryFlag': None, 'CONGRESSDISTRICT': None, 'CONGRESS_DISTRICT_PERF': '""'}
{'Code': '914500', 'Text': 'SPECIAL PROGRAMS-RESERVE'}
{'url': 'https://www.nsf.gov/awardsearch/download?DownloadFileName=1988&All=true', 'xml': '8858820.xml'}