Insect Neural Development
{'Code': '08090200', 'Directorate': {'Abbreviation': 'BIO', 'LongName': 'Direct For Biological Sciences'}, 'Division': {'Abbreviation': 'IOS', 'LongName': 'Division Of Integrative Organismal Systems'}}
{'SignBlockName': 'Steven C. McLoon', 'PO_EMAI': None, 'PO_PHON': None}
This research will continue to examine axonal pathfinding in the                developing wing of Drosophila by (1) identifying the ionic basis                of the physiological difference by studying the neurons in a                    series of putative channel mutants; (2) by looking for the                      expression of the corresponding genes in the neurons using a                    variety of molecular probes given to us by the labs who have                    cloned the genes; (3) by testing the hypothesis that                            developmentally important hormones form the causal link between                 time of development, physiological behavior and choice of central               pathway by growing the developing wings in vitro and manipulating               the levels of 20-hydroxyecdysone and juvenile hormone.                          (4) Hormone manipulating results in a change in the number of                   cells that bind anti-HRP, the usual agent for identifying nerve                 cells in insects.  In order to assess whether all the cells that                develop under these conditions are neurons, the P.I. will apply                 multiple criteria of neural identity.
{'FirstName': 'John', 'LastName': 'Palka', 'PI_MID_INIT': 'M', 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'John M Palka', 'EmailAddress': 'palka@u.washington.edu', 'NSF_ID': '000112082', 'StartDate': '09/01/1988', 'EndDate': None, 'RoleCode': 'Principal Investigator'}
{'Name': 'University of Washington', 'CityName': 'SEATTLE', 'ZipCode': '981951016', 'PhoneNumber': '2065434043', 'StreetAddress': '4333 BROOKLYN AVE NE', 'StreetAddress2': None, 'CountryName': 'United States', 'StateName': 'Washington', 'StateCode': 'WA', 'CONGRESSDISTRICT': '07', 'CONGRESS_DISTRICT_ORG': 'WA07', 'ORG_UEI_NUM': 'HD1WMN6945W6', 'ORG_LGL_BUS_NAME': 'UNIVERSITY OF WASHINGTON', 'ORG_PRNT_UEI_NUM': None}
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{'Code': '1190', 'Text': 'DEVELOPMENTAL NEUROSCIENCE'}
{'url': 'https://www.nsf.gov/awardsearch/download?DownloadFileName=1988&All=true', 'xml': '8812865.xml'}