Dyanmics and Stability of Membrane Systems (REU Supplement)
{'Code': '07020000', 'Directorate': {'Abbreviation': 'ENG', 'LongName': 'Directorate For Engineering'}, 'Division': {'Abbreviation': 'CBET', 'LongName': 'Div Of Chem, Bioeng, Env, & Transp Sys'}}
{'SignBlockName': 'Robert M. Wellek', 'PO_EMAI': None, 'PO_PHON': None}
This project is an interrelated theoretical and experimental work on            the kinetics of adhesion and fusion of cell-size vesicles, based on             physical chemistry and hydrodynamics of thin films.  The study focuses          on the similarity between the kinetics of aggregation and coalescence           of bubbles and drops in colloid systems and the kinetics of adhesion,           instability, and fusion in membrane systems, where the specific                 mechanical and permeability properties of membranes are taken into              account.  The rate of mutual approach of deformable permeable                   membranes, the stability of films between interacting membranes, the            rate of expansion of membrane contact during adhesion, and the rate of          shape relaxation after membrane fusion are evaluated theoretically.             From these results, the total times of vesicle adhesion and fusion are          calculated as a function of the membrane tension, membrane                      permeability, intermembrane forces and liquid film viscosity.  The              times of adhesion and fusion of cell-size phospholipid vesicles, held           by micropipettes, are measured as a function of the vesicle membrane            tensions and the concentration of ions in the water solutions where the         vesicles are placed.  The theoretically calculated times of adhesion            and fusion are compared with the experimentally measured values for             phosphatidylcholine and phosphatidylserine vesicles.
{'FirstName': 'Rakesh', 'LastName': 'Jain', 'PI_MID_INIT': 'K', 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'Rakesh K Jain', 'EmailAddress': None, 'NSF_ID': '000237802', 'StartDate': '01/15/1985', 'EndDate': None, 'RoleCode': 'Principal Investigator'}
{'Name': 'Carnegie-Mellon University', 'CityName': 'PITTSBURGH', 'ZipCode': '152133815', 'PhoneNumber': '4122688746', 'StreetAddress': '5000 FORBES AVE', 'StreetAddress2': None, 'CountryName': 'United States', 'StateName': 'Pennsylvania', 'StateCode': 'PA', 'CONGRESSDISTRICT': '18', 'CONGRESS_DISTRICT_ORG': 'PA18', 'ORG_UEI_NUM': 'U3NKNFLNQ613', 'ORG_LGL_BUS_NAME': 'CARNEGIE MELLON UNIVERSITY', 'ORG_PRNT_UEI_NUM': 'U3NKNFLNQ613'}
{'Name': None, 'CityName': None, 'StateCode': None, 'ZipCode': None, 'StreetAddress': None, 'CountryCode': None, 'CountryName': None, 'StateName': None, 'CountryFlag': None, 'CONGRESSDISTRICT': None, 'CONGRESS_DISTRICT_PERF': '""'}
{'Code': '1414', 'Text': 'INTERFAC PROCESSES & THERMODYN'}
{'url': 'https://www.nsf.gov/awardsearch/download?DownloadFileName=1984&All=true', 'xml': '8413990.xml'}