Neural Signalling of Salt Intake
{'Code': '08090200', 'Directorate': {'Abbreviation': 'BIO', 'LongName': 'Direct For Biological Sciences'}, 'Division': {'Abbreviation': 'IOS', 'LongName': 'Division Of Integrative Organismal Systems'}}
{'SignBlockName': 'Christopher Comer', 'PO_EMAI': None, 'PO_PHON': None}
Salt or osmo-sensors play a major role in the neural and                   neuroendocrine regulation of salt-water balance in the human                    body.  However, there is no agreement on their precise location                 in the brain or periphery, their morphological features are                     unknown, their mode of activation incompletely understood, and                  their neural integration virtually unexplored.  Dr. Alex                        Baertschi has developed an animal model system to study these                   issues.  He will first determine the physiological significance                 of a splanchnic salt-input sensitive mechanism by comparing the                 effects of systemic and gastric saline infusions on plasma                      arginine vasopressin.  Next he will determine sensory mechanisms                and peripheral neural pathways for salt-input detection.                        Finally, he will determine the central route of splanchnic salt-                input sensitive afferents to the magnocellular hypothalamic                     vasopressinergic nuclei.  This work is important as we try to                   understand how the nervous system codes for and integrates                      information concerning salt intake.  This work is relevant to                   eating behaviors both normal and abnormal and may give us a more                defined knowledge regarding salt sensors in the human body.
{'FirstName': 'Alex', 'LastName': 'Baertschi', 'PI_MID_INIT': 'J', 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'Alex J Baertschi', 'EmailAddress': None, 'NSF_ID': '000242226', 'StartDate': '03/01/1989', 'EndDate': None, 'RoleCode': 'Principal Investigator'}
{'Name': 'University of Virginia Main Campus', 'CityName': 'CHARLOTTESVILLE', 'ZipCode': '229034833', 'PhoneNumber': '4349244270', 'StreetAddress': '1001 EMMET ST N', 'StreetAddress2': None, 'CountryName': 'United States', 'StateName': 'Virginia', 'StateCode': 'VA', 'CONGRESSDISTRICT': '05', 'CONGRESS_DISTRICT_ORG': 'VA05', 'ORG_UEI_NUM': 'JJG6HU8PA4S5', 'ORG_LGL_BUS_NAME': 'RECTOR & VISITORS OF THE UNIVERSITY OF VIRGINIA', 'ORG_PRNT_UEI_NUM': None}
{'Name': 'University of Virginia School of Medicine', 'CityName': 'Charlottesville', 'StateCode': 'VA', 'ZipCode': '22908', 'StreetAddress': None, 'CountryCode': 'US', 'CountryName': 'United States', 'StateName': 'Virginia', 'CountryFlag': '1', 'CONGRESSDISTRICT': '05', 'CONGRESS_DISTRICT_PERF': 'VA05'}
{'Code': '1191', 'Text': 'BEHAVIORAL NEUROSCIENCE'}
{'url': 'https://www.nsf.gov/awardsearch/download?DownloadFileName=1988&All=true', 'xml': '8819877.xml'}