Sieving of Gels During Electrophoresis
{'Code': '08070400', 'Directorate': {'Abbreviation': 'BIO', 'LongName': 'Direct For Biological Sciences'}, 'Division': {'Abbreviation': 'MCB', 'LongName': 'Div Of Molecular and Cellular Bioscience'}}
{'SignBlockName': 'Arthur Kowalsky', 'PO_EMAI': None, 'PO_PHON': None}
Gel electrophoresis has been used to fractionate macromolecules for             studies in all fields of biochemistry.  However, the sieving of gels            during electrophoresis is not understood physically.  Sieving can be            used to determine the size of spheres and, in some cases, the molecular         weight of random coils.                                                                                                                                         Drs. Serwer and Griess propose to:  (a) obtain and use data for the             testing of previously proposed hypotheses that quantitatively describe          the sieving of gels and (b) determine the effect of a particles's shape         on its sieving during gel electrophoresis.  These objectives are                components of a research program for understanding the assembly and             purposeful motion of macromolecules, using bacteriophages as model              systems.  It is anticipated that achieving these objectives will also           serve as a foundation for utilization of gel electrophoresis in several         areas of biochemistry, microbiology, colloid chemistry and cellular             biology.
[{'FirstName': 'Gary', 'LastName': 'Griess', 'PI_MID_INIT': 'A', 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'Gary A Griess', 'EmailAddress': 'Griess@uthscsa.edu', 'NSF_ID': '000403542', 'StartDate': '08/01/1987', 'EndDate': None, 'RoleCode': 'Co-Principal Investigator'}, {'FirstName': 'Philip', 'LastName': 'Serwer', 'PI_MID_INIT': None, 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'Philip Serwer', 'EmailAddress': 'Serwer@uthscsa.edu', 'NSF_ID': '000147896', 'StartDate': '08/01/1987', 'EndDate': None, 'RoleCode': 'Principal Investigator'}]
{'Name': 'University of Texas Health Science Center San Antonio', 'CityName': 'SAN ANTONIO', 'ZipCode': '782293901', 'PhoneNumber': '2105672340', 'StreetAddress': '7703 FLOYD CURL DR', 'StreetAddress2': None, 'CountryName': 'United States', 'StateName': 'Texas', 'StateCode': 'TX', 'CONGRESSDISTRICT': '20', 'CONGRESS_DISTRICT_ORG': 'TX20', 'ORG_UEI_NUM': 'C3KXNLTAAY98', 'ORG_LGL_BUS_NAME': 'THE UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO', 'ORG_PRNT_UEI_NUM': None}
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{'Code': '114400', 'Text': 'Molecular Biophysics'}
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