Modeling and Control of the Crystallization Kinetics of     Organic Electrolytes
{'Code': '07020000', 'Directorate': {'Abbreviation': 'ENG', 'LongName': 'Directorate For Engineering'}, 'Division': {'Abbreviation': 'CBET', 'LongName': 'Div Of Chem, Bioeng, Env, & Transp Sys'}}
{'SignBlockName': 'Charles Alexander Garris, Jr.', 'PO_EMAI': None, 'PO_PHON': None}
The proposed research relates to development of principles for                                                                                                  engineering the crystallization product of organic electrolyte                                                                                                  solutions.  Models to describe adequately the nucleation and                                                                                                    growth rates and to elucidate precipitation mechanisms of                       organic electrolytes have been proposed for experimental                        verification.  Emphasis will be placed on developing                            heuristics for predicting the inclusion of the additives in                                                                                                     the precipitate and the role of included additives on the                       properties of the precipitate crystals.                                                                                                                         The significance of this research is its relation to the                        design of solids with carefully engineered physicochemical and                                                                                                  biological properties.  These properties can dramatically                       affect the biological activity of pharmaceutical products.  It                                                                                                  is expected that the goals of the project will be accomplished                                                                                                  by studying the precipitation kinetics of a monoprotic acid                                                                                                     (diphenylhydantoin) and an amino acid (glutamic acid).  The                                                                                                     influence of other amino acids and other structurally related                                                                                                   additives will be studied from both a structural and a kinetic                                                                                                  points of view.
{'FirstName': 'Nair', 'LastName': 'Rodriguez-Hornedo', 'PI_MID_INIT': None, 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'Nair Rodriguez-Hornedo', 'EmailAddress': 'nrh@umich.edu', 'NSF_ID': '000479136', 'StartDate': '10/01/1989', 'EndDate': None, 'RoleCode': 'Principal Investigator'}
{'Name': 'Regents of the University of Michigan - Ann Arbor', 'CityName': 'ANN ARBOR', 'ZipCode': '481091079', 'PhoneNumber': '7347636438', 'StreetAddress': '1109 GEDDES AVE, SUITE 3300', 'StreetAddress2': None, 'CountryName': 'United States', 'StateName': 'Michigan', 'StateCode': 'MI', 'CONGRESSDISTRICT': '06', 'CONGRESS_DISTRICT_ORG': 'MI06', 'ORG_UEI_NUM': 'GNJ7BBP73WE9', 'ORG_LGL_BUS_NAME': 'REGENTS OF THE UNIVERSITY OF MICHIGAN', 'ORG_PRNT_UEI_NUM': None}
{'Name': None, 'CityName': None, 'StateCode': None, 'ZipCode': None, 'StreetAddress': None, 'CountryCode': None, 'CountryName': None, 'StateName': None, 'CountryFlag': None, 'CONGRESSDISTRICT': None, 'CONGRESS_DISTRICT_PERF': '""'}
{'Code': '1417', 'Text': 'Interfacial Engineering Progra'}
{'url': 'https://www.nsf.gov/awardsearch/download?DownloadFileName=1988&All=true', 'xml': '8818627.xml'}