On the Effect of Thermo-Chemical Pretreatment on the        Enzymatic Hydrolysis of Insoluble Lignocellulosic Substrates
{'Code': '07020000', 'Directorate': {'Abbreviation': 'ENG', 'LongName': 'Directorate For Engineering'}, 'Division': {'Abbreviation': 'CBET', 'LongName': 'Div Of Chem, Bioeng, Env, & Transp Sys'}}
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Narrative: This proposal targets the important problem of                       converting lignocellulosic substrates to liquid fuel, namely                    ethanol.  In addition, the sugar solution resulting from enzyme                 hydrolysis can be used as a general fermentation substrate.                                                                                                     An attempt will be made to quantify the kinetics of the enzymatic               hydrolysis of thermo-chemically pretreated lignocellulosic                      material.  In particular, the work will relate the physical and                 chemical effects of the "steam-explosion" pretreatment to the                   kinetics of the subsequent hydrolysis of woody biomass.  Area and               pore volume available to enzyme action, degree of polymerization,               crystallinity index, and lignin content and morphological state                 will be measured in order to characterize the substrate.  These                 variables, as well as the enzyme concentration and activity and                 product concentration, are to be followed throughout the                        hydrolysis reaction.                                                                                                                                            Fundamental studies of this kind will help to lay a basis for the               development of new processes for enzymatically converting                       insoluble lignocellulosic substrates to more valuable products,                 and to provide a better understanding of heterogeneous enzyme                   kinetics in general.  The resulting mathematical models will be                 sensitive to process behavior and therefore be valuable in the                  design and development of efficient, economical production of                   useful products via enzymatic hydrolysis of insoluble                           lignocellulosic substrates.
{'FirstName': 'Alvin', 'LastName': 'Converse', 'PI_MID_INIT': 'O', 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'Alvin O Converse', 'EmailAddress': None, 'PI_PHON': None, 'NSF_ID': '000206114', 'StartDate': '07/01/1987', 'EndDate': None, 'RoleCode': 'Principal Investigator'}
{'Name': 'Dartmouth College', 'CityName': 'HANOVER', 'ZipCode': '037552170', 'PhoneNumber': '6036463007', 'StreetAddress': '7 LEBANON ST', 'StreetAddress2': None, 'CountryName': 'United States', 'StateName': 'New Hampshire', 'StateCode': 'NH', 'CONGRESSDISTRICT': '02', 'CONGRESS_DISTRICT_ORG': 'NH02', 'ORG_UEI_NUM': 'EB8ASJBCFER9', 'ORG_LGL_BUS_NAME': 'TRUSTEES OF DARTMOUTH COLLEGE', 'ORG_PRNT_UEI_NUM': 'EB8ASJBCFER9'}
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[{'Code': '1402', 'Text': 'BIOCHEMICAL & BIOMASS ENG'}, {'Code': '9120', 'Text': 'CROSS-DIRECTORATE PROGRAMS'}]
{'url': 'https://www.nsf.gov/awardsearch/download?DownloadFileName=1987&All=true', 'xml': '8701010.xml'}