Markers of Cellular Differentiation in Mammalian CNS
{'Code': '08090200', 'Directorate': {'Abbreviation': 'BIO', 'LongName': 'Direct For Biological Sciences'}, 'Division': {'Abbreviation': 'IOS', 'LongName': 'Division Of Integrative Organismal Systems'}}
{'SignBlockName': 'Steven C. McLoon', 'PO_EMAI': None, 'PO_PHON': None}
The general goal of the project is to study neuronal                            differentiation in the mammalian nervous system by generating                   markers for molecules expressed by neurons early in their                       development.  These markers will then be used to follow the                     expression of early-expressed molecules in vivo and in vitro.                   The study has two main objectives:  1)  To identify antigens                    expressed by early postmitotic neurons.  2)  To examine the                     developmental regulation of the expression of identified                        molecules.                                                                                                                                                      These experiments are designed to generate reagents with which to               identify specific cell classes and developmentally significant                  changes in neurons.  Such reagents could then be used to follow                 normal and abnormal neural development and to test hypotheses of                developmental mechanisms.  The long term goal of these                          experiments is to obtain a molecular description of developmental               events which could be used to assay the effects of teratogenic or               genetic insult on neural development.
{'FirstName': 'Susan', 'LastName': 'Hockfield', 'PI_MID_INIT': None, 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'Susan Hockfield', 'EmailAddress': 'susan.hockfield@yale.edu', 'NSF_ID': '000171867', 'StartDate': '08/01/1988', 'EndDate': None, 'RoleCode': 'Principal Investigator'}
{'Name': 'Yale University', 'CityName': 'NEW HAVEN', 'ZipCode': '065113572', 'PhoneNumber': '2037854689', 'StreetAddress': '150 MUNSON ST', 'StreetAddress2': None, 'CountryName': 'United States', 'StateName': 'Connecticut', 'StateCode': 'CT', 'CONGRESSDISTRICT': '03', 'CONGRESS_DISTRICT_ORG': 'CT03', 'ORG_UEI_NUM': 'FL6GV84CKN57', 'ORG_LGL_BUS_NAME': 'YALE UNIV', 'ORG_PRNT_UEI_NUM': 'FL6GV84CKN57'}
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[{'Code': '1190', 'Text': 'DEVELOPMENTAL NEUROSCIENCE'}, {'Code': '9120', 'Text': 'CROSS-DIRECTORATE PROGRAMS'}]
{'url': 'https://www.nsf.gov/awardsearch/download?DownloadFileName=1988&All=true', 'xml': '8812163.xml'}