Immunogenetic Studies of a Marsupial (Monodelphis Domestica)
{'Code': '08060200', 'Directorate': {'Abbreviation': 'BIO', 'LongName': 'Direct For Biological Sciences'}, 'Division': {'Abbreviation': 'DCB', 'LongName': 'Division of Cellular Biosciences'}}
{'SignBlockName': 'Maryanna P. Henkart', 'PO_EMAI': None, 'PO_PHON': None}
In the coming year, this research will concentrate on completing           several of the projects begun under previous support. The Class I               membrane antigens of the Major Histocompatibility Complex of the                marsupial Monodelphis domestica will be isolated and characterized              using the Western blot procedure.  Studies of the baseline immune               responses will be completed and attempts to tolerize newborns to                particulate and soluble antigens will be continued.  Further data on            the response of lymphocytes to mitogens and the behavior of                     Monodelphis lymphocytes in mixed lymphocyte cultures will be                    obtained.  Studies will be continued of the development of alpha-               fetoprotein in animals of various stages, and antisera against alpha-           fetoprotein will be produced.  Finally, studies will be continued of            the genetic control of the enzyme polymorphisms and blood groups                already defined.                                                                     The major objective of this project is to study the                        immunogenetic and biochemical genetic systems of a marsupial. Another           objective is to involve bright undergraduate students in basic                  research in an established and active research laboratory.
{'FirstName': 'William', 'LastName': 'Stone', 'PI_MID_INIT': 'H', 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'William H Stone', 'EmailAddress': None, 'PI_PHON': None, 'NSF_ID': '000105836', 'StartDate': '01/01/1988', 'EndDate': None, 'RoleCode': 'Principal Investigator'}
{'Name': 'Trinity University', 'CityName': 'SAN ANTONIO', 'ZipCode': '782124674', 'PhoneNumber': '2109997246', 'StreetAddress': '1 TRINITY PL', 'StreetAddress2': None, 'CountryName': 'United States', 'StateName': 'Texas', 'StateCode': 'TX', 'CONGRESSDISTRICT': '21', 'CONGRESS_DISTRICT_ORG': 'TX21', 'ORG_UEI_NUM': 'U4SCDG6B6NM8', 'ORG_LGL_BUS_NAME': 'TRINITY UNIVERSITY', 'ORG_PRNT_UEI_NUM': None}
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{'Code': '9120', 'Text': 'CROSS-DIRECTORATE PROGRAMS'}
{'url': 'https://www.nsf.gov/awardsearch/download?DownloadFileName=1987&All=true', 'xml': '8709860.xml'}