Protein Transport by Ligand Gradients
{'Code': '07020000', 'Directorate': {'Abbreviation': 'ENG', 'LongName': 'Directorate For Engineering'}, 'Division': {'Abbreviation': 'CBET', 'LongName': 'Div Of Chem, Bioeng, Env, & Transp Sys'}}
{'SignBlockName': 'Fred G. Heineken', 'PO_EMAI': None, 'PO_PHON': None}
The research deals with protein separations by a new phenomenon,                "ligand-induced transport."  The protein diffusion across a                     porous membrane is enhanced by the concentration gradient of a                  ligand to which the protein binds.  The high but different fluxes of            different proteins provide the basis for an efficient separation                process.  In this research six enzymes will be studied, each with two-          three ligands.  The fluxes will be measured by a new fluorescence               spectroscopy technique.                                                         The expected results of the research are twofold:  (a) to provide a             fundamental understanding of protein/ligand interactions; and (b)               possibly leads to a new, efficient technique for separation and                 purification of proteins.
[{'FirstName': 'John', 'LastName': 'Anderson', 'PI_MID_INIT': 'L', 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'John L Anderson', 'EmailAddress': 'johna@andrew.cmu.edu', 'NSF_ID': '000238193', 'StartDate': '02/01/1988', 'EndDate': None, 'RoleCode': 'Principal Investigator'}, {'FirstName': 'Michael', 'LastName': 'Domach', 'PI_MID_INIT': 'M', 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'Michael M Domach', 'EmailAddress': 'md0q@andrew.cmu.edu', 'NSF_ID': '000100579', 'StartDate': '02/01/1988', 'EndDate': None, 'RoleCode': 'Co-Principal Investigator'}]
{'Name': 'Carnegie-Mellon University', 'CityName': 'PITTSBURGH', 'ZipCode': '152133815', 'PhoneNumber': '4122688746', 'StreetAddress': '5000 FORBES AVE', 'StreetAddress2': None, 'CountryName': 'United States', 'StateName': 'Pennsylvania', 'StateCode': 'PA', 'CONGRESSDISTRICT': '12', 'CONGRESS_DISTRICT_ORG': 'PA12', 'ORG_UEI_NUM': 'U3NKNFLNQ613', 'ORG_LGL_BUS_NAME': 'CARNEGIE MELLON UNIVERSITY', 'ORG_PRNT_UEI_NUM': 'U3NKNFLNQ613'}
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[{'Code': '1402', 'Text': 'BIOCHEMICAL & BIOMASS ENG'}, {'Code': '1417', 'Text': 'Interfacial Engineering Progra'}]
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