A Hollow Fiber Bioreactor for the Production of Monoclonal  Antibodies
{'Code': '07020000', 'Directorate': {'Abbreviation': 'ENG', 'LongName': 'Directorate For Engineering'}, 'Division': {'Abbreviation': 'CBET', 'LongName': 'Div Of Chem, Bioeng, Env, & Transp Sys'}}
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A radial flow hollow fiber mammalian cell culture system is to be used          for continuous culture of non-anchorage dependent murine hybridoma.             Continuous production of monoclonal antibodies is being investigated.           Hybridoma cell lines PM-81 and AML-2-23 are used for mass culture and           monoclonal antibodies production studies.  The project also evaluates           the feasibility of ;itin situ;ro membrane separation of antibodies, and         investigates the long-term stability of the culture and antibodies              production.  Analysis is complemented by mathematical models which              incorporate hydrodynamics, membrane transport, and transient behavior           of culture systems.
{'FirstName': 'Pao', 'LastName': 'Chau', 'PI_MID_INIT': 'C', 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'Pao C Chau', 'EmailAddress': 'pcchau@iacs5.ucsd.edu', 'NSF_ID': '000238439', 'StartDate': '10/01/1985', 'EndDate': None, 'RoleCode': 'Principal Investigator'}
{'Name': 'University of California-San Diego', 'CityName': 'LA JOLLA', 'ZipCode': '920930021', 'PhoneNumber': '8585344896', 'StreetAddress': '9500 GILMAN DR', 'StreetAddress2': None, 'CountryName': 'United States', 'StateName': 'California', 'StateCode': 'CA', 'CONGRESSDISTRICT': '50', 'CONGRESS_DISTRICT_ORG': 'CA50', 'ORG_UEI_NUM': 'UYTTZT6G9DT1', 'ORG_LGL_BUS_NAME': 'UNIVERSITY OF CALIFORNIA, SAN DIEGO', 'ORG_PRNT_UEI_NUM': None}
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[{'Code': '1402', 'Text': 'BIOCHEMICAL & BIOMASS ENG'}, {'Code': '1417', 'Text': 'Interfacial Engineering Progra'}]
{'url': 'https://www.nsf.gov/awardsearch/download?DownloadFileName=1985&All=true', 'xml': '8512318.xml'}