Development of a Synchrotron X-ray Area Detector
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A high performance data collection system for x-ray                             crystallography has been implemented, although it has not reached               a final stage of development.  Current work will involve x-ray                  crystallographic data collection on intact gap junctions, intact                invertebrate muscle, collagen structure and relaxed and rigor                   muscle, topomyosin, lysozyme, TMV protein disk aggregated,                      fibrinogen, polyoma minichromosomes, and incoherent scattering                  from protein crystals.  In addition, the equipment and experience               used in building this tv detector will be used to develop an area               detector for synchrotron radiation, initially for use at                        Brookhaven National Lab's National Syncrotron Light Source                      (NSLS).  The detector system will make possible a substantial                   improvement in the rate of data collection and in the accuracy of               the data.  Consequently, this also extends the range of                         experimental problems in structural biology that can be studied.
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