Analysis of Centromere-Specific Genes in Yeast
{'Code': '08070100', 'Directorate': {'Abbreviation': 'BIO', 'LongName': 'Direct For Biological Sciences'}, 'Division': {'Abbreviation': 'MCB', 'LongName': 'Div Of Molecular and Cellular Bioscience'}}
{'SignBlockName': 'DeLill Nasser', 'PO_EMAI': None, 'PO_PHON': None}
The long-term goal of this ROW Career Advancement Award is to                   determine how the Kinetochore region of a eucaryotic chromosome                 associates with a spindle fiber to ensure proper chromosome                     segregation.  Eventually, the investigator will investigate the                 role the kinetochore plays in organizing the chromosomes in the                 nucleus during interphase.  This specific project will make use                 of both genetic and biochemical approaches.  Antibodies will be                 prepared and used to determine the cellular location of proteins                for various mutant cells and will facilitate the isolation of                   components with which the proteins interact.  These powerful                    approaches will permit direct investigation of the requirements                 for kinetochore assembly and function in yeast.  This approach,                 combined with classical genetic approaches, make yeast an                       excellent model eucaryotic system for determining the molecular                 mechanisms underlying successful cell division.
{'FirstName': 'Molly', 'LastName': 'Fitzgerald-Hayes', 'PI_MID_INIT': None, 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'Molly Fitzgerald-Hayes', 'EmailAddress': None, 'NSF_ID': '000099917', 'StartDate': '07/01/1988', 'EndDate': None, 'RoleCode': 'Principal Investigator'}
{'Name': 'University of Massachusetts Amherst', 'CityName': 'AMHERST', 'ZipCode': '010039252', 'PhoneNumber': '4135450698', 'StreetAddress': '101 COMMONWEALTH AVE', 'StreetAddress2': None, 'CountryName': 'United States', 'StateName': 'Massachusetts', 'StateCode': 'MA', 'CONGRESSDISTRICT': '02', 'CONGRESS_DISTRICT_ORG': 'MA02', 'ORG_UEI_NUM': 'VGJHK59NMPK9', 'ORG_LGL_BUS_NAME': 'UNIVERSITY OF MASSACHUSETTS', 'ORG_PRNT_UEI_NUM': 'VGJHK59NMPK9'}
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[{'Code': '9120', 'Text': 'CROSS-DIRECTORATE PROGRAMS'}, {'Code': '9145', 'Text': 'SPECIAL PROGRAMS-RESERVE'}]
{'url': 'https://www.nsf.gov/awardsearch/download?DownloadFileName=1988&All=true', 'xml': '8809121.xml'}