Acquisition of a 600 MHz NMR Spectrometer for Biochemical   Studies.
{'Code': '08000000', 'Directorate': {'Abbreviation': 'BIO', 'LongName': 'Direct For Biological Sciences'}, 'Division': {'Abbreviation': 'BIO', 'LongName': 'Direct For Biological Sciences'}}
{'SignBlockName': 'Machi F. Dilworth', 'PO_EMAI': None, 'PO_PHON': None}
This proposal requests funds to purchase a 600 NMz NMR                          spectrometer to be used for biochemical studies b a primary group               of six investigators and four secondary investigators.  The                     overall objectives of the biochemical studies are to develop,                   refine, and apply high-resolution NMR methods to a number of                    biochemical problems in the areas of enzyme, protein, and peptide               structures and interactions and antibiotic-DNA interactions; to                 learn the structures in solution of several enzymes, regulatory                 proteins, their peptide fragments, and the structural basis of                  their specific interactions with substrates and nucleic acids;                  and to determine at the chemical level the mode of interaction of               bleomycin and its metal complexes with DNA and of intercalating                 agents with defined sequences of RNA.
{'FirstName': 'Albert', 'LastName': 'Mildvan', 'PI_MID_INIT': 'S', 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'Albert S Mildvan', 'EmailAddress': None, 'NSF_ID': '000220182', 'StartDate': '12/15/1987', 'EndDate': None, 'RoleCode': 'Principal Investigator'}
{'Name': 'Johns Hopkins University', 'CityName': 'BALTIMORE', 'ZipCode': '212182608', 'PhoneNumber': '4439971898', 'StreetAddress': '3400 N CHARLES ST', 'StreetAddress2': None, 'CountryName': 'United States', 'StateName': 'Maryland', 'StateCode': 'MD', 'CONGRESSDISTRICT': '07', 'CONGRESS_DISTRICT_ORG': 'MD07', 'ORG_UEI_NUM': 'FTMTDMBR29C7', 'ORG_LGL_BUS_NAME': 'THE JOHNS HOPKINS UNIVERSITY', 'ORG_PRNT_UEI_NUM': None}
{'Name': 'Johns Hopkins University School of Medicine', 'CityName': 'Baltimore', 'StateCode': 'MD', 'ZipCode': '21218', 'StreetAddress': 'Homewood Divisions, Room 113', 'CountryCode': 'US', 'CountryName': 'United States', 'StateName': 'Maryland', 'CountryFlag': '1', 'CONGRESSDISTRICT': '07', 'CONGRESS_DISTRICT_PERF': 'MD07'}
{'Code': '1108', 'Text': 'INSTRUMENTAT & INSTRUMENT DEVP'}
{'url': 'https://www.nsf.gov/awardsearch/download?DownloadFileName=1986&All=true', 'xml': '8612318.xml'}