Isolation and Characterization of the Blue-Green            Photoreceptor of H Halobium
{'Code': '08070400', 'Directorate': {'Abbreviation': 'BIO', 'LongName': 'Direct For Biological Sciences'}, 'Division': {'Abbreviation': 'MCB', 'LongName': 'Div Of Molecular and Cellular Bioscience'}}
{'SignBlockName': 'Marcia Steinberg', 'PO_EMAI': None, 'PO_PHON': None}
The phototactic archaeobacterium H. halobium contains the                  light-driven proton and chloride pumps bacteriorhodopsin and                    halorhodopsin.  It has been found that mutants deficient in                     both rhodopsins are still phototactic, and that the light                       signal receptors are actually two retinal pigments, the sensory                 rhodopsins (sR's) I and II.  They constitute a primitive color                  discrimination system based on pigments chemically similar to                   the light and color sensing pigments of animals.                                     The goal of this proposal is to isolate, purify and                        characterize the recently identified sR-II receptor, and                        compare its function and properties with those of the sensory                   pigments of higher organisms.  The results should yield new                     insights on the principles which underlie the design of                         membrane proteins for energy and sensory transduction and their                 evolutionary development.
{'FirstName': 'Roberto', 'LastName': 'Bogomolni', 'PI_MID_INIT': 'A', 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'Roberto A Bogomolni', 'EmailAddress': 'bogo@chemistry.ucsc.edu', 'NSF_ID': '000438621', 'StartDate': '07/01/1988', 'EndDate': None, 'RoleCode': 'Principal Investigator'}
{'Name': 'University of California-Santa Cruz', 'CityName': 'SANTA CRUZ', 'ZipCode': '950641077', 'PhoneNumber': '8314595278', 'StreetAddress': '1156 HIGH ST', 'StreetAddress2': None, 'CountryName': 'United States', 'StateName': 'California', 'StateCode': 'CA', 'CONGRESSDISTRICT': '19', 'CONGRESS_DISTRICT_ORG': 'CA19', 'ORG_UEI_NUM': 'VXUFPE4MCZH5', 'ORG_LGL_BUS_NAME': 'UNIVERSITY OF CALIFORNIA SANTA CRUZ', 'ORG_PRNT_UEI_NUM': None}
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[{'Code': '114400', 'Text': 'Molecular Biophysics'}, {'Code': '912000', 'Text': 'CROSS-DIRECTORATE PROGRAMS'}]
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