Computer for Ultrastructure Research and Molecular Biology
{'Code': '08080102', 'Directorate': {'Abbreviation': 'BIO', 'LongName': 'Direct For Biological Sciences'}, 'Division': {'Abbreviation': 'DBI', 'LongName': 'Div Of Biological Infrastructure'}}
{'SignBlockName': 'Machi F. Dilworth', 'PO_EMAI': None, 'PO_PHON': None}
This group of investigators in structural biology utilize the                   conventional electron microscope and computer tomography in                     association with the high-voltage electron microscope.  The                     computer-based components of these projects rely on the                         availability of raster graphics, large disk space, and memory.                  The funded equipment of this grant consists of DEC and SUN                      computer hardware which will provide high speed computing                       capability. The use of shared instrumentation is appropriate                    because the bulk of existing software developed in-house has been               written with a view towards accommodating a wide range of                       applications, and because a shared facility leads to the most                   efficient use of resources.                                                     Visualization of the cell and its substructural components has                  been and continues to be one of the important goals of modern                   biology.  Electron microscopy provides magnification powerful                   enough to image cellular organelles and macromolecular complexes.               The complex 3-dimensional reconstruction of serial sections is                  performed by computer, providing a picture of these complexes.                  Structures to be investigated by electron microscopy and high                   voltage electron microscopy include ribosomes, membrane channels,               components of the mitotic apparatus, and cilia.
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{'Code': '1108', 'Text': 'INSTRUMENTAT & INSTRUMENT DEVP'}
{'url': 'https://www.nsf.gov/awardsearch/download?DownloadFileName=1987&All=true', 'xml': '8721474.xml'}