Affinity Extraction for Monoclonal Antibody Production
{'Code': '07020000', 'Directorate': {'Abbreviation': 'ENG', 'LongName': 'Directorate For Engineering'}, 'Division': {'Abbreviation': 'CBET', 'LongName': 'Div Of Chem, Bioeng, Env, & Transp Sys'}}
{'SignBlockName': 'Jeffrey Foltz', 'PO_EMAI': 'jfoltz@nsf.gov', 'PO_PHON': '7032924231'}
Encapsulated affinity adsorbents will be developed and will be                  employed in one-step, whole-broth isolation/purification of monoclonal          antiboidies (Mabs).  The capsules consist of hydrogel-membrane wall             and an encapsulated, ligand-bonded polymer adsorbent.  The capsules             are highly selective due to the combined kinetic selectivity of the             membrane and the affinity selectivity of the bonded polymer.  The               capsules are easily retrievable due to their large sizes (0.5 - 1.5             mm).  Process schemes for using the capsules including chromatography           will be studied.                                                                                                                                                The research has the potential to offer new and economic approaches             for binding and separating biological molecules from complex mixtures.
{'FirstName': 'Henry Yee-Neen', 'LastName': 'Wang', 'PI_MID_INIT': None, 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'Henry Yee-Neen Wang', 'EmailAddress': 'hywang@umich.edu', 'NSF_ID': '000309732', 'StartDate': '06/01/1988', 'EndDate': None, 'RoleCode': 'Principal Investigator'}
{'Name': 'Regents of the University of Michigan - Ann Arbor', 'CityName': 'ANN ARBOR', 'ZipCode': '481091079', 'PhoneNumber': '7347636438', 'StreetAddress': '1109 GEDDES AVE, SUITE 3300', 'StreetAddress2': None, 'CountryName': 'United States', 'StateName': 'Michigan', 'StateCode': 'MI', 'CONGRESSDISTRICT': '06', 'CONGRESS_DISTRICT_ORG': 'MI06', 'ORG_UEI_NUM': 'GNJ7BBP73WE9', 'ORG_LGL_BUS_NAME': 'REGENTS OF THE UNIVERSITY OF MICHIGAN', 'ORG_PRNT_UEI_NUM': None}
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[{'Code': '1417', 'Text': 'Interfacial Engineering Progra'}, {'Code': '9120', 'Text': 'CROSS-DIRECTORATE PROGRAMS'}, {'Code': '9145', 'Text': 'SPECIAL PROGRAMS-RESERVE'}]
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