Analysis of the Staphylococcus Aureus Chromosome
{'Code': '08070100', 'Directorate': {'Abbreviation': 'BIO', 'LongName': 'Direct For Biological Sciences'}, 'Division': {'Abbreviation': 'MCB', 'LongName': 'Div Of Molecular and Cellular Bioscience'}}
{'SignBlockName': 'Philip Harriman', 'PO_EMAI': None, 'PO_PHON': None}
The major long-term objective of the research of this                           laboratory is to define the chromosome of Staphylococcus                        aureus, and thus gain a better understanding of the manner                      whereby extrachromosomal elements contribute to its                             characteristics, and the degree of diversity that exits                         within the genus Staphylococcus.  The specific aims of this                     proposed research are to (l) complete the genetic continuity                    of the chromosome of lytic group III S. aureus, and to                          continue to map additional markers of this lytic group, (2)                     initiate the development of chromosome maps in lytic groups I                   and II of S. aureus (3) develop the pulse field gradient gel                    electrophoresis technique for use with S. aureus to study the                   genomic organization of the chromosome in different lytic                       groups, and to identify the approximate chromosomal location                    of new markers on the chromosome, (4) identify the                              chromosomal loci responsible for the recombination-deficient                    phenotype in lytic group I and III, and (5) identify the                        nature and location of the genetic deteminants of restriction                   and modification.
{'FirstName': 'Peter', 'LastName': 'Pattee', 'PI_MID_INIT': 'A', 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'Peter A Pattee', 'EmailAddress': None, 'NSF_ID': '000087763', 'StartDate': '07/01/1987', 'EndDate': None, 'RoleCode': 'Principal Investigator'}
{'Name': 'Iowa State University', 'CityName': 'AMES', 'ZipCode': '500112103', 'PhoneNumber': '5152945225', 'StreetAddress': '1350 BEARDSHEAR HALL', 'StreetAddress2': '515 MORRILL ROAD', 'CountryName': 'United States', 'StateName': 'Iowa', 'StateCode': 'IA', 'CONGRESSDISTRICT': '04', 'CONGRESS_DISTRICT_ORG': 'IA04', 'ORG_UEI_NUM': 'DQDBM7FGJPC5', 'ORG_LGL_BUS_NAME': 'IOWA STATE UNIVERSITY OF SCIENCE AND TECHNOLOGY', 'ORG_PRNT_UEI_NUM': None}
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[{'Code': '1112', 'Text': 'Genetic Mechanisms'}, {'Code': '9120', 'Text': 'CROSS-DIRECTORATE PROGRAMS'}]
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