Hunger and Satiety Produced by Simple Sugar
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{'SignBlockName': 'Kathie L. Olsen', 'PO_EMAI': None, 'PO_PHON': None}
Most current theories of hunger predict that glucose should be                  satiating.  None would predict that glucose or other simple                     sugars could act as hunger or appetite stimulants, yet the                      hunger- and appetite-producing effects of simple sugars have been               demonstrated experimentally.  For example, Dr. Geiselman has                    shown that, when glucose was slowly infused into the duodenum,                  rabbits decreased their subsequent food intake, as would be                     expected.  However, when glucose was rapidly infused into the                   duodenum, the rabbits nearly doubled their food intake.                                                                                                         Dr. Geiselman's research is attempting to determine why glucose                 sometimes is satiating and at other times acts to produce hunger.               She will carry out experiments designed to determine the hormonal               and metabolic mechanisms that produce satiety in response to slow               infusions of glucose into the duodenum and hunger in response to                fast infusions of glucose into the duodenum.                                                                                                                    Dr. Geiselman's research will provide insight into the basic                    physiological mechanisms that control food intake and, more                     specifically, that relate sugar intake to hunger motivation.  Dr.               Geiselman hypothesizes:  (1) that glucose is satiating when it is               followed by a moderate rise in insulin level that is insufficient               to produce hypoglycemia, (2) that glucose stimulates further                    hunger when it is followed by a great elevation in insulin level                that is sufficient to produce hypoglycemia, and (3) that the                    hunger-stimulating effect of glucose occurs when glucose is                     readily converted to fat.
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[{'Code': '1160', 'Text': 'IBN ANIMAL BEHAVIOR'}, {'Code': '1193', 'Text': 'NEUROENDOCRINOLOGY'}]
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