Biochemistry of Enzyme Sorting
{'Code': '08070600', 'Directorate': {'Abbreviation': 'BIO', 'LongName': 'Direct For Biological Sciences'}, 'Division': {'Abbreviation': 'MCB', 'LongName': 'Div Of Molecular and Cellular Bioscience'}}
{'SignBlockName': 'Maryanna P. Henkart', 'PO_EMAI': None, 'PO_PHON': None}
This is a proposal to study the maturation of                       lysosomal enzymes in Dictyostelium discoideum.  Using a sulfation               defective mutant for the project, and an in vitro system                        developed in his lab or sulfation of endogenous lysosomal                       precursors and exogenous lysosomal enzymes, the investigator will               focus on one of the enzymes, N-acetylglucosaminidase.  Since a                  nearly complete cDNA copy of the mRNA has been cloned by the                    investigator, it would be easier to characterize this enzyme.
{'FirstName': 'Arnold', 'LastName': 'Kaplan', 'PI_MID_INIT': None, 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'Arnold Kaplan', 'EmailAddress': None, 'PI_PHON': '5015756356', 'NSF_ID': '000172874', 'StartDate': '01/01/1989', 'EndDate': None, 'RoleCode': 'Principal Investigator'}
{'Name': 'Saint Louis University', 'CityName': 'SAINT LOUIS', 'ZipCode': '631032006', 'PhoneNumber': '3149773925', 'StreetAddress': '221 N GRAND BLVD', 'StreetAddress2': None, 'CountryName': 'United States', 'StateName': 'Missouri', 'StateCode': 'MO', 'CONGRESSDISTRICT': '01', 'CONGRESS_DISTRICT_ORG': 'MO01', 'ORG_UEI_NUM': 'JNBLLTBTLLD8', 'ORG_LGL_BUS_NAME': 'SAINT LOUIS UNIVERSITY', 'ORG_PRNT_UEI_NUM': 'JNBLLTBTLLD8'}
{'Name': 'Saint Louis University School of Medicine', 'CityName': 'St Louis', 'StateCode': 'MO', 'ZipCode': '631032006', 'StreetAddress': '221 North Grand Boulevard', 'CountryCode': 'US', 'CountryName': 'United States', 'StateName': 'Missouri', 'CountryFlag': '1', 'CONGRESSDISTRICT': '01', 'CONGRESS_DISTRICT_PERF': 'MO01'}
{'Code': '1114', 'Text': 'Cellular Dynamics and Function'}
{'url': 'https://www.nsf.gov/awardsearch/download?DownloadFileName=1988&All=true', 'xml': '8800112.xml'}