U.S.-Japan Cooperative Research: Structure-Function         Relationships in the F1-ATPase
{'Code': '01090000', 'Directorate': {'Abbreviation': 'O/D', 'LongName': 'Office Of The Director'}, 'Division': {'Abbreviation': 'OISE', 'LongName': 'Office Of Internatl Science &Engineering'}}
{'SignBlockName': 'Charles Wallace', 'PO_EMAI': None, 'PO_PHON': None}
This award will enable Professor William Allison of the University              of California, San Diego to collaborate with Dr. Masasuke Yoshida               of the Tokyo Institute of Technology, Japan.  The research will be              aimed at defining the functional roles of amino acid side chains                that have been implicated to be essential for the activity of                   mitochondrial and bacterial F1-ATPase, a complex, but important                 component of energy transducing membranes.  The focus will be on                the functional role of two tyrosine residues in the F1-ATPase from              bovine heart mitochondria.  The study will employ the techniques of             chemical modification and site-directed mutagenesis.                                                                                                            Use of the in vitro mutagenesis approach, in combination with                   chemical modification techniques, will provide important                        information on the structure-function relationship in the                       F1-ATPases.  Dr. Allison has pioneered the use of chemical                      modification techniques for the study of ATP synthase and                       Dr. Yoshida is an expert on the technique of site-directed                      mutagenesis.
{'FirstName': 'William', 'LastName': 'Allison', 'PI_MID_INIT': 'S', 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'William S Allison', 'EmailAddress': None, 'NSF_ID': '000106624', 'StartDate': '03/15/1988', 'EndDate': None, 'RoleCode': 'Principal Investigator'}
{'Name': 'University of California-San Diego', 'CityName': 'LA JOLLA', 'ZipCode': '920930021', 'PhoneNumber': '8585344896', 'StreetAddress': '9500 GILMAN DR', 'StreetAddress2': None, 'CountryName': 'United States', 'StateName': 'California', 'StateCode': 'CA', 'CONGRESSDISTRICT': '50', 'CONGRESS_DISTRICT_ORG': 'CA50', 'ORG_UEI_NUM': 'UYTTZT6G9DT1', 'ORG_LGL_BUS_NAME': 'UNIVERSITY OF CALIFORNIA, SAN DIEGO', 'ORG_PRNT_UEI_NUM': None}
{'Name': None, 'CityName': None, 'StateCode': None, 'ZipCode': None, 'StreetAddress': None, 'CountryCode': None, 'CountryName': None, 'StateName': None, 'CountryFlag': None, 'CONGRESSDISTRICT': None, 'CONGRESS_DISTRICT_PERF': '""'}
{'Code': '5921', 'Text': 'JAPAN'}
{'url': 'https://www.nsf.gov/awardsearch/download?DownloadFileName=1987&All=true', 'xml': '8716615.xml'}