Structure-Function Relationships in Biological System
{'Code': '08070400', 'Directorate': {'Abbreviation': 'BIO', 'LongName': 'Direct For Biological Sciences'}, 'Division': {'Abbreviation': 'MCB', 'LongName': 'Div Of Molecular and Cellular Bioscience'}}
{'SignBlockName': 'Kamal Shukla', 'PO_EMAI': None, 'PO_PHON': None}
Dr. Ho continues to study the molecular basis of transport                      processes in cell membranes by characterizing the molecular                     structures of and intermolecular interactions between individual                membrane-associated components.  The active transport of L-                     glutamine in membrane vesicles of E. Coli will be used as a model               for investigating the essential processes in active transport,                  namely recognition, translocation, recovery and energy coupling.                Techniques to be used include molecular genetics, X-ray                         crystallography and NMR.                                                                                                                                        Cell membranes are the site of a large number of biological                     processes. Thus, knowledge of their molecular biology is one of                 the most important and active areas of research at the present                  time.  An understanding of the molecular organization and dynamic               interactions of the protein and lipid components of membranes is                essential for a detailed description of a wide variety of normal                and pathological cellular processes.
{'FirstName': 'Chien', 'LastName': 'Ho', 'PI_MID_INIT': None, 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'Chien Ho', 'EmailAddress': 'chienho@andrew.cmu.edu', 'NSF_ID': '000211183', 'StartDate': '05/01/1989', 'EndDate': None, 'RoleCode': 'Principal Investigator'}
{'Name': 'Carnegie-Mellon University', 'CityName': 'PITTSBURGH', 'ZipCode': '152133815', 'PhoneNumber': '4122688746', 'StreetAddress': '5000 FORBES AVE', 'StreetAddress2': None, 'CountryName': 'United States', 'StateName': 'Pennsylvania', 'StateCode': 'PA', 'CONGRESSDISTRICT': '18', 'CONGRESS_DISTRICT_ORG': 'PA18', 'ORG_UEI_NUM': 'U3NKNFLNQ613', 'ORG_LGL_BUS_NAME': 'CARNEGIE MELLON UNIVERSITY', 'ORG_PRNT_UEI_NUM': 'U3NKNFLNQ613'}
{'Name': 'Carnegie-Mellon University', 'CityName': 'PITTSBURGH', 'StateCode': 'PA', 'ZipCode': '152133815', 'StreetAddress': '5000 FORBES AVE', 'CountryCode': 'US', 'CountryName': 'United States', 'StateName': 'Pennsylvania', 'CountryFlag': '1', 'CONGRESSDISTRICT': '18', 'CONGRESS_DISTRICT_PERF': 'PA18'}
{'Code': '1164', 'Text': 'MOLECULAR BIOPHYSICS'}
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