The Conformation of Nucleic Acids
{'Code': '08070400', 'Directorate': {'Abbreviation': 'BIO', 'LongName': 'Direct For Biological Sciences'}, 'Division': {'Abbreviation': 'MCB', 'LongName': 'Div Of Molecular and Cellular Bioscience'}}
{'SignBlockName': 'Arthur Kowalsky', 'PO_EMAI': None, 'PO_PHON': None}
Dr. Johnson is continuing his work on the determination of the                  secondary structure of biological polymers in solution using                    circular dichroism (CD) spectroscopy.  CD is an excellent                       technique for monitoring the secondary structure of optically                   active biological molecules.  It is very sensitive to the                       orientation of nearest neighbor chromophores and it can be used                 when these molecules are in solution.  It is also planned to                    make extensive use of 2D NMR in the near future.                                                                                                                The focus of this research is to solve structural problems of                   current interest which involve nucleic acids.  A special CD                     spectrometer has been developed on which measurements in the                    vacuum ultraviolet region can be made.  This region is rich in                  information about the structure and conformation of                             macromolecules.  Dr. Johnson will also work on improving the                    theory of CD so that the spectrum of a macromolecule can be                     directly related to its structure and conformation.
{'FirstName': 'W.', 'LastName': 'Johnson', 'PI_MID_INIT': 'C', 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'W. C Johnson', 'EmailAddress': None, 'NSF_ID': '000198252', 'StartDate': '11/01/1988', 'EndDate': None, 'RoleCode': 'Principal Investigator'}
{'Name': 'Oregon State University', 'CityName': 'CORVALLIS', 'ZipCode': '973318655', 'PhoneNumber': '5417374933', 'StreetAddress': '1500 SW JEFFERSON AVE', 'StreetAddress2': None, 'CountryName': 'United States', 'StateName': 'Oregon', 'StateCode': 'OR', 'CONGRESSDISTRICT': '04', 'CONGRESS_DISTRICT_ORG': 'OR04', 'ORG_UEI_NUM': 'MZ4DYXE1SL98', 'ORG_LGL_BUS_NAME': 'OREGON STATE UNIVERSITY', 'ORG_PRNT_UEI_NUM': None}
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{'Code': '1164', 'Text': 'MOLECULAR BIOPHYSICS'}
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