Population Genetics of Recombination Modifiers
{'Code': '08010207', 'Directorate': {'Abbreviation': 'BIO', 'LongName': 'Direct For Biological Sciences'}, 'Division': {'Abbreviation': 'DEB', 'LongName': 'Division Of Environmental Biology'}}
{'SignBlockName': 'Joann P. Roskoski', 'PO_EMAI': None, 'PO_PHON': None}
Recombination is a genetic consequence of sexual                        reproduction; it results in chromosomes containing genes from                   both parents.  The goal of this project is to understand how                    natural selection can act on recombination.  The form of genetic                variation for recombination determines how the response to                      selection can occur.  This variation will be studied in a                       population of the fruit fly Drosophila melanogaster.  Genes on                  the X and third chromosomes will be studied to see how they                     influence recombination in the X chromosome.  This will show the                form of the variation for recombination due to both linked and                  unlinked modifier genes, and how they interact.                                         Theoretical analysis will aid the interpretation of the                 experimental results.  Mathematical analysis and simulations will               be done for models of multiple recombination modifiers.  The goal               is to see how the net selection on recombination is related to                  the selective effects from the individual modifiers.
{'FirstName': 'Lisa', 'LastName': 'Brooks', 'PI_MID_INIT': None, 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'Lisa Brooks', 'EmailAddress': 'lbrooks@brownvm.bitnet', 'NSF_ID': '000453036', 'StartDate': '02/01/1988', 'EndDate': None, 'RoleCode': 'Principal Investigator'}
{'Name': 'Brown University', 'CityName': 'PROVIDENCE', 'ZipCode': '029129100', 'PhoneNumber': '4018632777', 'StreetAddress': '1 PROSPECT ST', 'StreetAddress2': None, 'CountryName': 'United States', 'StateName': 'Rhode Island', 'StateCode': 'RI', 'CONGRESSDISTRICT': '01', 'CONGRESS_DISTRICT_ORG': 'RI01', 'ORG_UEI_NUM': 'E3FDXZ6TBHW3', 'ORG_LGL_BUS_NAME': 'BROWN UNIVERSITY', 'ORG_PRNT_UEI_NUM': None}
{'Name': None, 'CityName': None, 'StateCode': None, 'ZipCode': None, 'StreetAddress': None, 'CountryCode': None, 'CountryName': None, 'StateName': None, 'CountryFlag': None, 'CONGRESSDISTRICT': None, 'CONGRESS_DISTRICT_PERF': '""'}
{'Code': '1127', 'Text': 'Evolutionary Processes'}
{'url': 'https://www.nsf.gov/awardsearch/download?DownloadFileName=1987&All=true', 'xml': '8717191.xml'}