Acquisition of a 500 MHz NMR Spectrometer for Structure     Analysis of Biomolecules
{'Code': '08000000', 'Directorate': {'Abbreviation': 'BIO', 'LongName': 'Direct For Biological Sciences'}, 'Division': {'Abbreviation': 'BIO', 'LongName': 'Direct For Biological Sciences'}}
{'SignBlockName': 'Machi F. Dilworth', 'PO_EMAI': None, 'PO_PHON': None}
This proposal requests funds for the purchase of a 500 MHz NMR                  spectrometer plus computer, Skywarrior array processor, digital                 plotter, and laser printer to be used for protein structural                    studies by a group of four primary investigators from the                       Biophysics Research Division of the Institute of Science and                    Technology at the University of Michigan.  The requested NMR will               be used in the development of improved methodology, and the                     techniques will be applied to small proteins.  Particular                       emphasis will be given to small proteins that do not crystallize                and to proteins with indications of differences between crystal                 and solution structure.  Additionally the effects of site-                      directed mutagenesis on conformation, dynamics, stability, and                  folding of proteins will be investigated.  Dr. Wagner's                         accomplishments in the field of 2-D NMR applied to problems of                  protein structure-function are extremely impressive; he is one of               the world leaders in the area.
{'FirstName': 'Gerhard', 'LastName': 'Wagner', 'PI_MID_INIT': None, 'PI_SUFX_NAME': None, 'PI_FULL_NAME': 'Gerhard Wagner', 'EmailAddress': 'gerhard_wagner@hms.harvard.edu', 'NSF_ID': '000326872', 'StartDate': '11/15/1987', 'EndDate': None, 'RoleCode': 'Principal Investigator'}
{'Name': 'Regents of the University of Michigan - Ann Arbor', 'CityName': 'ANN ARBOR', 'ZipCode': '481091079', 'PhoneNumber': '7347636438', 'StreetAddress': '1109 GEDDES AVE, SUITE 3300', 'StreetAddress2': None, 'CountryName': 'United States', 'StateName': 'Michigan', 'StateCode': 'MI', 'CONGRESSDISTRICT': '06', 'CONGRESS_DISTRICT_ORG': 'MI06', 'ORG_UEI_NUM': 'GNJ7BBP73WE9', 'ORG_LGL_BUS_NAME': 'REGENTS OF THE UNIVERSITY OF MICHIGAN', 'ORG_PRNT_UEI_NUM': None}
{'Name': None, 'CityName': None, 'StateCode': None, 'ZipCode': None, 'StreetAddress': None, 'CountryCode': None, 'CountryName': None, 'StateName': None, 'CountryFlag': None, 'CONGRESSDISTRICT': None, 'CONGRESS_DISTRICT_PERF': '""'}
{'Code': '1108', 'Text': 'INSTRUMENTAT & INSTRUMENT DEVP'}
{'url': 'https://www.nsf.gov/awardsearch/download?DownloadFileName=1986&All=true', 'xml': '8615223.xml'}