Silent Information Regulator (SIR) proteins are proteins conserved from yeast to humans that are involved in organizing heterochromatin at telomeres, rDNA and at silent loci including, in yeast, the hidden mating type loci.
Silent Information Regulator (SIR) proteins are proteins. These proteins are conserved from yeast to humans and at silent loci including the hidden mating type loci. This was in yeast. These humans are involved in organizing heterochromatin at telomeres. Telomeres are rdna.