By the end of the series, Rei's brother had died but she had become insane and Miko points out that it is impossible to let her know that her brother is dead.
Rei's brother had died. This was by the end of the series. She had become insane. This was by the end of the series. It is impossible to let her know that her brother is dead. Miko points out this. This is by the end of the series.