During bladder filling, neurons within the PMC are turned off, but at a critical level of bladder distention, the afferent activity arising from mechanoreceptors in the bladder wall switches the PMC on and enhances its activity.
Neurons within the PMC are turned off. This was during bladder filling. The afferent activity arising from mechanoreceptors in the bladder wall switches the PMC on. This is at a critical level of bladder distention. The afferent activity arising from mechanoreceptors in the bladder wall enhances its activity. This is at a critical level of bladder distention.