When a drug fails at this stage, the financial losses can be catastrophic, but using the traditional model of pre-clinical development it is difficult to predict side effects that occur at a low frequency, side effects which can cause the trial to fail.
The financial losses can be catastrophic. A drug fails at this stage. It is using the traditional model of pre-clinical development. It is difficult to predict side effects. These side effects occur at a low frequency. A low frequency is side effects. These side effects can cause the trial to fail.