A prototypical eight TMS topology apparently arose by intragenic duplication of a four transmembrane segment (TMS) unit, and possibly, a two TMS α-helical hairpin structure was the precursor of the 4 TMS repeat unit.
A prototypical eight TMS topology apparently arose by intragenic duplication of a four transmembrane segment (TMS) unit. A two TMS α-helical hairpin structure was the precursor of the 4 TMS repeat unit. This was possibly.