Inhibitors of G6PT1 are the most studied as this subunit holds the greatest promise as a drug target for disease treatment, as it catalyzes the rate limiting step in glucose production through gluconeogenesis or glycogenolysis and thus without its function, these two processes cannot occur.
These two processes cannot occur. This was what inhibitors of G6PT1 are the most studied. As it catalyzes the rate step in glucose production through gluconeogenesis or glycogenolysis and thus without its function. This is what this subunit holds the greatest promise as a drug target for disease treatment. This rate is limiting.