HNIW is prepared by first condensing benzylamine with glyoxal under acidic and dehydrating conditions, with four of the resulting benzyl groups removed by hydrogenolysis using palladium on carbon and hydrogen and the resulting secondary amine groups are acetylated in acetic anhydride.
HNIW is prepared by first condensing benzylamine with glyoxal under acidic and dehydrating conditions groups. This was with four of the resulting benzyl. These resulting benzyl groups are removed by hydrogenolysis. These hydrogenolysis are using palladium on carbon and hydrogen. The resulting secondary amine groups are acetylated in acetic anhydride.