It is caused by a hereditary deficiency of the enzyme glucocerebrosidase (also known as acid β-glucosidase), leading to an accumulation of its substrate, the fatty substance glucocerebroside (also known as glucosylceramide).
It is caused by a hereditary deficiency of the enzyme glucocerebrosidase (also known as acid β-glucosidase). A hereditary deficiency of the enzyme glucocerebrosidase (also known as acid β-glucosidase) is leading to an accumulation of its substrate (also known as glucosylceramide). Its substrate is the fatty substance glucocerebroside.