In extremely rare cases, repeated improper topical application of hydroquinone has been associated with exogenous ochronosis and most hydroquinone preparations contain the preservative sodium metabisulfite, which has been linked to rare cases of allergic reactions including anaphylaxis and severe asthma exacerbations in susceptible people.
Repeated improper topical application of hydroquinone has been associated with exogenous ochronosis including anaphylaxis in susceptible people. This was in extremely rare cases. Repeated improper topical application of hydroquinone has been associated with exogenous ochronosis including severe asthma exacerbations in susceptible people. This was in extremely rare cases. Most hydroquinone preparations contain the preservative sodium metabisulfite. This is in extremely rare cases. The preservative sodium metabisulfite has been linked to rare cases of allergic reactions including anaphylaxis in susceptible people. The preservative sodium metabisulfite has been linked to rare cases of allergic reactions including severe asthma exacerbations in susceptible people.