The dUTPase deficiency prevents the breakdown of dUTP, a nucleotide that normally replaces dTTP in RNA, resulting in an abundance of dUTP; the uracil deglycosidase deficiency prevents the removal of uracil from newly-synthesized DNA.
The dUTPase deficiency prevents the breakdown of dUTP. DUTP is a nucleotide. This nucleotide normally replaces dTTP in RNA. This nucleotide normally is resulting in an abundance of dUTP. The uracil deglycosidase deficiency prevents the removal of uracil from newly-synthesized DNA.