Two toxins, known as the pertussis toxin (or PTx) and adenylate cyclase (CyaA), cause phagocytes to convert too much ATP to cyclic AMP, which can cause disturbances in cellular signaling mechanisms, and prevent phagocytes from correctly responding to an infection.
Two toxins cause phagocytes to convert too much ATP to cyclic AMP and prevent phagocytes from correctly responding to an infection. Two toxins are known as the pertussis toxin (or PTx) and adenylate cyclase (CyaA). Cyclic AMP can cause disturbances in cellular signaling mechanisms.