PFK1 is activated by high concentration of AMP, but the most potent activator is fructose 2,6-bisphosphate, which is also produced from fructose-6-phosphate by PFK2.
PFK1 is activated by high concentration of AMP. The most potent activator is fructose 2,6-bisphosphate-6-phosphate by PFK2. Bisphosphate is also produced from fructose.