A GDP/GTP exchange factor (GEF) catalyzes the conversion from GDP-bound to GTP-bound forms, and GTP hydrolysis to GDP is catalyzed by a GTPase-activating protein (GAP).
A GDP/GTP exchange factor (GEF) catalyzes the conversion from GDP-bound to GTP-bound forms. The inherent GTP hydrolysis of Rabs can be enhancece by a GTPase-activating protein (GAP).