It thrived until the arrival of the Spanish in the 16th century (who called it Cuenca), after which the effects of European diseases and conquest, and assimilation by large native tribes, lead to abandonment of the settlement.
It thrived until the arrival of the Spanish in 1567, who established a fort there and called the settlement Cuenca. Effects of European diseases and conquest, and assimilation by large native tribes, lead to native abandonment of the settlement.