RxFiles, 2010; p.78 Pregabalin binds to the α 2 δ subunit of voltage-gated calcium channels (VGCCs) and modulates calcium influx at the nerve terminals, which may account for its therapeutic effect on neuropathic pain, anxiety, and seizures.
RxFiles, 2010; p.78 Pregabalin is classified as an anticonvulsant and binds to the α 2 δ subunit of voltage-gated calcium channels (VGCCs) which modulates calcium influx at nerve terminals. This may account for its therapeutic effect on neuropathic pain, anxiety, and seizures.