In atherosclerotic lesions, macrophages that express scavenger receptors on their plasma membrane aggressively uptake the oxidized LDL deposited in the blood vessel wall inside and develop into foam cells, likewise they secrete various inflammatory cytokines and accelerate the development of atherosclerosis.
In atherosclerotic lesions, macrophages that express scavenger receptors on their plasma membrane take up the oxidized LDL deposited in the blood vessel wall aggressively, and develop into foam cells. Likewise they secrete various inflammatory cytokines and accelerate the development of atherosclerosis.