It is most often seeen in the course of an active infection, during which the bone marrow is thought to increase production to such an extent that immature forms begin to escape into the systemic circulation.
It is most often seen in the course of an active infection and during other severe illnesses such as hypoxia and shock. In these conditions, the bone marrow is thought to increase production to such an extent that immature forms begin to escape into the systemic circulation.