By his second wife, Elizabeth Carlyle, he had a son John, ancestor of the Sempills of Beltrees, and English Born, married Mary Livingston in March 1565.
By his second wife, Elizabeth Carlyle, he had a son John, ancestor of the Sempills of Beltrees. A son, James Sempill, whose mother was said to be an Englishwoman, married Mary Livingston in March 1565.