Due to the emergence of pyrimethamine-resistant strains of "P. falciparum", pyrimethamine alone is seldom used now, but in combination with a long-acting sulfonamide such as sulfadiazine, it is widely used, though resistance to this combination is increasing.
Due to the emergence of pyrimethamine-resistant strains of "P. falciparum", pyrimethamine alone is seldom used now. In combination with a long-acting sulfonamide such as sulfadiazine, it is widely used, suchas in Fansidar though resistance to this combination is increasing.