Proguanil cannot be taken by people with severe renal impairment, pregnant women, or women who are breastfeeding children less than 5 kg. There have been reports of increased levels of liver enzymes, which may remain high up to 4 weeks after completion of treatment.
Proguanil cannot be taken by people with severe renal impairment, pregnant women, or women who are breastfeeding children less than 5 kg. There have been reports of increased levels of liver enzymes and hepatitis with this medication. If there are elevations of these enzymes, these may remain high up to 4 weeks after completion of treatment.