It is known as a norepinephrine dopamine disinhibitor (NDDI) because of its 5-HT 2C antagonistic properties of inhibiting 5HT, thereby disinhibiting DA and NE release by enhancing the activity of frontocortical dopaminergic and adrenergic pathways.
It is known as a norepinephrine dopamine disinhibitor (NDDI) due to its antagonism of the5-HT 2C Activation of 5ht2c receptors by Serotonin inhibit Dopamine and Norepinephrine release. Antagonism of 5ht2c results in an enhancement of DA and NE release and activity of frontocortical dopaminergic and adrenergic pathways.