The dUTPase deficiency prevents the breakdown of dUTP, a nucleotide that normally replaces dTTP in RNA, resulting in an abundance of dUTP; the uracil deglycosidase deficiency prevents the removal of uracil from newly-synthesized DNA.
The dUTPase deficiency prevents the breakdown of dUTP, resulting in a high level of dUTP in the cell. The uracil deglycosidase deficiency prevents the removal of uracil from newly-synthesized DNA.