Instruct: Given a question, retrieve documents that answer the question.
Query: When was ultrasound first used in medicine?
A contrast medium for medical ultrasonography is a formulation of encapsulated gaseous microbubbles to increase echogenicity of blood, discovered by Dr Raymond Gramiak in 1968 and named contrast-enhanced ultrasound. This contrast medical imaging modality is clinically used throughout the world, in particular for echocardiography in the United States and for ultrasound radiology in Europe and Asia.
The earliest study of endocrinology began in China. The Chinese were isolating sex and pituitary hormones from human urine and using them for medicinal purposes by 200 BCE. They used many complex methods, such as sublimation of steroid hormones. Another method specified by Chinese texts—the earliest dating to 1110—specified the use of saponin (from the beans of "Gleditsia sinensis") to extract hormones, but gypsum (containing calcium sulfate) was also known to have been used.
The use of music to soothe grief has been used since the time of David and King Saul. In I Samuel, David plays the Lyre in order to make King Saul feel relieved and better. It has since been used all over the world for treatment of various issues, though the first recorded use of official "music therapy" was in 1789 - an article titled "Music Physically Considered" by an unknown author was found in "Columbian Magazine". The creation and expansion of music therapy as a treatment modality thrived in the early to mid 1900's and while a number of organizations were created, none survived for long. It wasn't until 1950 that the National Association for Music Therapy was founded in New York that clinical training and certification requirements were created. In 1971, the American Association for Music Therapy was created, though at that time called the Urban Federation of Music Therapists. The Certification Board for Music Therapists was created in 1983 which strengthened the practice of music therapy and the trust that it was given. In 1998, the American Music Therapy Association was formed out of a merger between National and American Associations and is now the single largest music therapy organization in the world (American music therapy, 1998–2011). More about the history along with general information and application of music therapy can be found on the American Music Therapy Association website.
The Canadian inventor Reginald Fessenden was the first to conceive of using reflected seismic waves to infer geology. His work was initially on the propagation of acoustic waves in water, motivated by the sinking of the Titanic by an iceberg in 1912. He also worked on methods of detecting submarines during World War I. He applied for the first patent on a seismic exploration method in 1914, which was issued in 1917. Due to the war, he was unable to follow up on the idea. John Clarence Karcher discovered seismic reflections independently while working for the United States Bureau of Standards (now the National Institute of Standards and Technology) on methods of sound ranging to detect artillery. In discussion with colleagues, the idea developed that these reflections could aid in exploration for petroleum. With several others, many affiliated with the University of Oklahoma, Karcher helped to form the Geological Engineering Company, incorporated in Oklahoma in April, 1920. The first field tests were conducted near Oklahoma City, Oklahoma in 1921.
Germany has a long heritage of using electromagnetic waves for detecting objects. In 1888, Heinrich Hertz, who first demonstrated the existence of these waves, also noted that they, like light, were reflected by metal surfaces. In 1904, Christian Hülsmeyer obtained German and foreign patents for an apparatus, the "Telemobilskop", using a "spark gap transmitter" that could detect ships and prevent collisions; this is often cited as the first radar, but, without directly providing range, it does not qualify for this classification. With the advent of the radio tube and electronics, other detection-only systems were developed, but all used continuous waves and could not measure distance.
In 1933, physicist Rudolf Kühnhold, Scientific Director at the "Kriegsmarine" (German Navy) "Nachrichtenmittel-Versuchsanstalt" (NVA—Experimental Institute of Communication Systems) in Kiel, initiated experiments in the microwave region to measure the distance to a target. For the transmitter, he obtained assistance from two radio amateur operators, Paul-Günther Erbslöh and Hans-Karl Freiherr von Willisen. In January 1934, they formed at Berlin-Oberschöneweide the company "Gesellschaft für Elektroakustische und Mechanische Apparate" (GEMA) for this work.
The first use of an external defibrillator on a human was in 1947 by Claude Beck. The portable version of the defibrillator was invented in the mid-1960s by Frank Pantridge in Belfast, Northern Ireland, a pioneer in emergency medical treatment.
In 1857, Édouard-Léon Scott de Martinville invented the phonautograph, the first device that could record sound waves as they passed through the air. It was intended only for visual study of the recording and could not play back the sound. The recording medium was a sheet of soot-coated paper wrapped around a rotating cylinder carried on a threaded rod. A stylus, attached to a diaphragm through a series of levers, traced a line through the soot, creating a graphic record of the motions of the diaphragm as it was minutely propelled back and forth by the audio-frequency variations in air pressure.
Wang's laboratory was the first to report functional photoacoustic tomography, 3D photoacoustic microscopy (PAM), photoacoustic endoscopy, photoacoustic reporter gene imaging, the photoacoustic Doppler effect, the universal photoacoustic reconstruction algorithm, microwave-induced thermoacoustic tomography, ultrasound-modulated optical tomography, time-reversed ultrasonically encoded (TRUE) optical focusing, nonlinear photoacoustic wavefront shaping (PAWS), compressed ultrafast photography (10 trillion frames/s), Mueller-matrix optical coherence tomography, and optical coherence computed tomography. Wang was the recipient of several award, including NIH's FIRST, NSF's CAREER, NIH Director's Pioneer, and NIH Director's Transformative Research awards. WangWang was conferred with an honorary doctorate from the Lund University, Sweden. Wang also received the OSA C.E.K. Mees Medal "for seminal contributions to photoacoustic tomography and Monte Carlo modeling of photon transport in biological tissues and for leadership in the international biophotonics community". Prof. Wang has been conferred upon by an honorary doctorate degree by Lund University located in Sweden for his contributions towards the field of Biomedical Imaging.
From the first scientific investigations of the pendulum around 1602 by Galileo Galilei, the regular motion of pendulums was used for timekeeping, and was the world's most accurate timekeeping technology until the 1930s. The pendulum clock invented by Christian Huygens in 1658 became the world's standard timekeeper, used in homes and offices for 270 years, and achieved accuracy of about one second per year before it was superseded as a time standard by the quartz clock in the 1930s. Pendulums are also used in scientific instruments such as accelerometers and seismometers. Historically they were used as gravimeters to measure the acceleration of gravity in geophysical surveys, and even as a standard of length. The word "pendulum" is new Latin, from the Latin "pendulus", meaning 'hanging'.
The term medical ethics first dates back to 1803, when English author and physician Thomas Percival published a document describing the requirements and expectations of medical professionals within medical facilities. The Code of Ethics was then adapted in 1847, relying heavily on Percival's words. Over the years in 1903, 1912, and 1947, revisions have been made to the original document. The practice of Medical Ethics is widely accepted and practiced throughout the world.
John Edmond Buster (born July 18, 1941) working at the University of California at Los Angeles School of Medicine, directed the research team that performed history's first embryo transfer from one woman to another resulting in a live birth. It was performed at the Harbor-UCLA Medical Center, reported in July 1983, and culminated in the announcement of the first human birth February 3, 1984. In the procedure, an embryo that was just beginning to develop was transferred from the woman in whom it had been conceived by artificial insemination to another woman who gave birth to the infant 38 weeks later. The sperm used in the artificial insemination came from the husband of the woman who bore the baby.
The discovery of insulin at the University of Toronto in 1921 is considered among the most significant events in the history of medicine. The stem cell was discovered at the university in 1963, forming the basis for bone marrow transplantation and all subsequent research on adult and embryonic stem cells. This was the first of many findings at Toronto relating to stem cells, including the identification of pancreatic and retinal stem cells. The cancer stem cell was first identified in 1997 by Toronto researchers, who have since found stem cell associations in leukemia, brain tumors and colorectal cancer. Medical inventions developed at Toronto include the glycaemic index, the infant cereal Pablum, the use of protective hypothermia in open heart surgery and the first artificial cardiac pacemaker. The first successful single-lung transplant was performed at Toronto in 1981, followed by the first nerve transplant in 1988, and the first double-lung transplant in 1989. Researchers identified the maturation promoting factor that regulates cell division, and discovered the T-cell receptor, which triggers responses of the immune system. The university is credited with isolating the genes that cause Fanconi anemia, cystic fibrosis and early-onset Alzheimer's disease, among numerous other diseases. Between 1914 and 1972, the university operated the Connaught Medical Research Laboratories, now part of the pharmaceutical corporation Sanofi-Aventis. Among the research conducted at the laboratory was the development of gel electrophoresis.
The Greek physician Hippocrates, the founder of scientific medicine, was the first to deal with the anatomy and the pathology of human spine. Galen developed an interest in anatomy from his studies of Herophilus and Erasistratus. The concept of studying disease through the methodical dissection and examination of diseased bodies, organs, and tissues may seem obvious today, but there are few if any recorded examples of true autopsies performed prior to the second millennium. Though the pathology of contagion was understood by Muslim physicians since the time of Avicenna (980–1037) who described it in "The Canon of Medicine" (c. 1020), the first physician known to have made postmortem dissections was the Arabian physician Avenzoar (1091–1161) who proved that the skin disease scabies was caused by a parasite, followed by Ibn al-Nafis (b. 1213) who used dissection to discover pulmonary circulation in 1242. In the 15th century, anatomic dissection was repeatedly used by the Italian physician Antonio Benivieni (1443-1502) to determine cause of death. Antonio Benivieni is also credited with having introduced necropsy to the medical field. Perhaps the most famous early gross pathologist was Giovanni Morgagni (1682-1771). His magnum opus, "De Sedibus et Causis Morborum per Anatomem Indagatis", published in 1761, describes the findings of over 600 partial and complete autopsies, organised anatomically and methodically correlated with the symptoms exhibited by the patients prior to their demise. Although the study of normal anatomy was already well advanced at this date, "De Sedibus" was one of the first treatises specifically devoted to the correlation of diseased anatomy with clinical illness. By the late 1800s, an exhaustive body of literature had been produced on the gross anatomical findings characteristic of known diseases. The extent of gross pathology research in this period can be epitomized by the work of the Viennese pathologist (originally from Hradec Kralove in the Czech Rep.) Carl Rokitansky (1804-1878), who is said to have performed 20,000 autopsies, and supervised an additional 60,000, in his lifetime.
Photoacoustic tomography enables researchers to create three-dimensional images of deep tissue. A laser must be carefully tuned to excite specific bonds so that they "rattle", creating noise that can be detected and mapped by passive acoustic systems.
Modern air conditioning emerged from advances in chemistry during the 19th century, and the first large-scale electrical air conditioning was invented and used in 1902 by US inventor Willis Carrier. The introduction of residential air conditioning in the 1920s helped enable the great migration to the Sun Belt in the United States.
The Johns Hopkins Hospital (JHH) is the teaching hospital and biomedical research facility of the Johns Hopkins School of Medicine, located in Baltimore, Maryland, U.S. It was founded in 1889 using money from a bequest of over $7 million (1873 money, worth 134.7 million dollars in 2016) by city merchant, banker/financier, civic leader and philanthropist Johns Hopkins (1795-1873). Johns Hopkins Hospital and its school of medicine are considered to be the founding institutions of modern American medicine and the birthplace of numerous famous medical traditions including rounds, residents and house staff. Many medical specialties were formed at the hospital including neurosurgery, by Dr. Harvey Cushing; cardiac surgery by Dr. Alfred Blalock; and child psychiatry, by Dr. Leo Kanner.
Type 1 and type 2 diabetes were identified as separate conditions for the first time by the Indian physicians Sushruta and Charaka in 400–500 CE with type 1 associated with youth and type 2 with being overweight. The term "mellitus" or "from honey" was added by the Briton John Rolle in the late 1700s to separate the condition from diabetes insipidus, which is also associated with frequent urination. Effective treatment was not developed until the early part of the 20th century, when Canadians Frederick Banting and Charles Herbert Best isolated and purified insulin in 1921 and 1922. This was followed by the development of the long-acting insulin NPH in the 1940s.
Type 1 and type 2 diabetes were identified as separate conditions for the first time by the Indian physicians Sushruta and Charaka in 400–500 AD with type 1 associated with youth and type 2 with being overweight. The term "mellitus" or "from honey" was added by the Briton John Rolle in the late 1700s to separate the condition from diabetes insipidus which is also associated with frequent urination. Effective treatment was not developed until the early part of the 20th century when the Canadians Frederick Banting and Charles Best discovered insulin in 1921 and 1922. This was followed by the development of the long acting NPH insulin in the 1940s.
The Faculty of Medicine was one of the original four faculties constituting the University of Freiburg when it was founded in 1457. At first, the faculty consisted of only a single professor and few students. Medical education in the early modern era was mainly marked by theory and the reading of texts from classical and Arabic works that had been translated to Latin. As was common at the time, little emphasis was placed on patient care and bedside teaching in the curriculum and academic medicine shared the health care market with other professions such as barber surgeons, midwives, and lithtomists. During the period of enlightened absolutism, a new interest by the state in philanthropy saw the founding of several secular hospitals, a development which also revolutionized the medical curricula. Clinical classes were introduced and the university's first own clinic was founded in 1751.
The conventional telephone was invented independently by Alexander Bell and Elisha Gray in 1876. Antonio Meucci invented the first device that allowed the electrical transmission of voice over a line in 1849. However Meucci's device was of little practical value because it relied upon the electrophonic effect and thus required users to place the receiver in their mouth to "hear" what was being said. The first commercial telephone services were set-up in 1878 and 1879 on both sides of the Atlantic in the cities of New Haven and London.
The first microphone that enabled proper voice telephony was the (loose-contact) carbon microphone (then called transmitter). This was independently developed around 1878 by David Edward Hughes in England and Emile Berliner and Thomas Edison in the US. Although Edison was awarded the first patent in mid-1877, Hughes had demonstrated his working device in front of many witnesses some years earlier, and most historians credit him with its invention.
From the 1960s commercially available systems were introduced. Soon, other advances in electronics and piezoelectric materials enabled further improvements which meant that ultrasound was quickly adopted for use in medicine due to its rapid, accurate diagnostic capabilities which offered the possibility of prompt treatment. Alongside the improving imaging technology, acoustic Doppler velocimetry and medical ultrasonography color Doppler were developed, which have had a significant impact on many specialties, including radiology, obstetrics, gynecology, angiology and cardiology, and have provided even greater scope for ultrasound investigations. Since 1970, real-time scanners and pulsed Doppler, have enabled the use of ultrasound to study the function of the venous system. The first demonstration of color Doppler was achieved by Geoff Stevenson.
Further progress in the 1970s was made with the arrival of the microchip, and the ensuing exponential increase in processing power has meant the development of fast and powerful systems. These systems involving digital beamforming and greater signal enhancement, have introduced new methods of interpreting and displaying data.
Ultrasound is used in many different fields. Ultrasonic devices are used to detect objects and measure distances. Ultrasound imaging or sonography is often used in medicine. In the nondestructive testing of products and structures, ultrasound is used to detect invisible flaws. Industrially, ultrasound is used for cleaning, mixing, and accelerating chemical processes. Animals such as bats and porpoises use ultrasound for locating prey and obstacles. Scientists are also studying ultrasound using graphene diaphragms as a method of communication.
Ultrasound in Medicine and Biology is a monthly peer-reviewed medical journal published by Elsevier on behalf of the World Federation for Ultrasound in Medicine and Biology. It covers ultrasound technology in clinical diagnostic, interventional and therapeutic applications, including the physics, engineering, and technology of ultrasound in medicine and biology. It was established in 1973. The editor-in-chief is Christy K. Holland (University of Cincinnati) since 2006. The founding editor was Denis N. White, who served from 1973 to 1992 and was succeeded by Peter N. T. Wells.
Sackler began his career practicing medicine, where he specialized in biological psychiatry. In the early 1940s he joined medical advertising agency William Douglas McAdams Inc. From 1949 - 1954, he served as a research director at Creedmoor Institute for Psychobiological Studies. Sackler collaborated on 140 papers based on neuroendocrinology, psychiatry, and experimental medicine. He was the first doctor to use ultrasound for diagnosis, identified histamine as a hormone, and advocated for its use as an alternative to electroconvulsive therapy. He is also credited with helping to racially integrate New York City's first blood banks.