Instruct: Given a question, retrieve relevant passages that answer the question.
Query: Can a needlestick injury be fatal?
Needlestick injuries are among the top three injuries that occur among material-recovery facility workers who sort through trash to remove recyclable items from the community-collected garbage. Housekeeping and janitorial workers in public sites, including hotels, airports, indoor and outdoor recreational venues, theaters, retails stores, and schools are at daily risk of exposure to contaminated syringes. Needlestick injuries that occur in children from discarded needles in community settings, such as parks and playgrounds, are especially concerning. Not only for families but also for the entire community. While the exact number of needlestick injuries in children in the US is unknown, even one injury in a child is enough to cause public alarm. Studies in Canada have reported 274 injuries from needlesticks in children with the majority being boys (64.2%) and occurring from needles discarded in streets and/or parks (53.3%).
Early on in his time in Ambridge, Neil suffered from Leptospirosis, a disease contracted through rats. Hewlett recalls Neil was in hospital and "very close to losing his life". "Like all good dramas, we carried it through to the point –is he going to live, is he going to die? I lived – thank you (laughs), so that was quite interesting to play."
Faculty provides care for thousands suffering from mild to traumatic brain injuries. The concussion clinic at Medstar NRH focuses primarily on this form of brain injury and is regarded as one of the best in the country according to U.S. News & World Report. 75 percent of all traumatic brain injuries that occur are concussions. Traumatic brain injuries contribute to a third of all deaths in the United States with over 1.5 million brain injuries occurring each year. During their stay, patients are also educated on precautions they can take to prevent a future incidence.
Self-poisoning with agricultural pesticides represents a major hidden public health problem accounting for approximately one-third of all suicides worldwide. It is one of the most common forms of self-injury in the Global South. The World Health Organization estimates that 300,000 people die from self-harm each year in the Asia-Pacific region alone. Most cases of intentional pesticide poisoning appear to be impulsive acts undertaken during stressful events, and the availability of pesticides strongly influences the incidence of self poisoning. Pesticides are the agents most frequently used by farmers and students in India to commit suicide.
The botulinum toxin can cause a severe flaccid paralytic disease in humans and other animals and is the most potent toxin known to mankind, natural or synthetic, with a lethal dose of 1.3–2.1 ng/kg in humans.
, medical authorities concluded that 1,140 people who worked, lived, or studied in Lower Manhattan at the time of the attack have been diagnosed with cancer as a result of "exposure to toxins at Ground Zero". It has been reported that over 1,400 9/11 rescue workers who responded to the scene in the days and months after the attacks have since died. At least 11 pregnancies were lost as a result of 9/11.
"Most estimates concerning the extent of acute pesticide poisoning have been based on data from hospital admissions which would include only the more serious cases. The latest estimate by a WHO task group indicates that there may be 1 million serious unintentional poisonings each year and in addition 2 million people hospitalized for suicide attempts with pesticides. This necessarily reflects only a fraction of the real problem. On the basis of a survey of self-reported minor poisoning carried out in the Asian region, it is estimated that there could be as many as 25 million agricultural workers in the developing world suffering an episode of poisoning each year." In Canada in 2007 more than 6000 cases of acute pesticide poisoning occurred.
The third needle type consists of circular needles, which are long, flexible double-pointed needles. The two tapered ends (typically long) are rigid and straight, allowing for easy knitting; however, the two ends are connected by a flexible strand (usually nylon) that allows the two ends to be brought together. Circular needles are typically 24-60 inches long, and are usually used singly or in pairs; again, the width of the knitted piece may be significantly longer than the length of the circular needle. Special kits are available that allow circular needles of various lengths and diameters to be made as needed; rigid ends of various diameters may be screwed into strands of various lengths. The ability to work from either end of one needle is convenient in several types of knitting, such as slip-stitch versions of double knitting. Circular needles may be used for flat or circular knitting.
There are four basic types of knitting needles (also called "knitting pins"). The first and most common type consists of two slender, straight sticks tapered to a point at one end, and with a knob at the other end to prevent stitches from slipping off. Such needles are usually 10-16 inches long but, due to the compressibility of knitted fabrics, may be used to knit pieces significantly wider. The most important property of needles is their diameter, which ranges from below 2 mm to 25 mm (roughly 1 inch). The diameter affects the size of stitches, which affects the gauge of the knitting and the elasticity of the fabric. Thus, a simple way to change gauge is to use different needles, which is the basis of uneven knitting. Although knitting needle diameter is often measured in millimeters, there are several different size systems, particularly those specific to the United States, the United Kingdom and Japan; a conversion table is given in the knitting needle article. Such knitting needles may be made out of any materials, but the most common materials are metals, wood, bamboo, and plastic. Different materials have different frictions and grip the yarn differently; slick needles such as metallic needles are useful for swift knitting, whereas rougher needles such as bamboo are less prone to dropping stitches. The knitting of new stitches occurs only at the tapered ends, and needles with lighted tips have been sold to allow knitters to knit in the dark.
A knitting needle or knitting pin is a tool in hand-knitting to produce knitted fabrics. They generally have a long shaft and taper at their end, but they are not nearly as sharp as sewing needles. Their purpose is two-fold. The long shaft "holds" the active (unsecured) stitches of the fabric, to prevent them from unravelling, whereas the tapered ends are used to "form new stitches". Most commonly, a new stitch is formed by inserting the tapered end through an active stitch, catching a loop (also called a bight) of fresh yarn and drawing it through the stitch; this secures the initial stitch and forms a new active stitch in its place. In specialized forms of knitting the needle may be passed between active stitches being held on another needle, or indeed between/through inactive stitches that have been knit previously.
Generally, the risks to prosectors are low. Cadavers used for teaching purposes are embalmed before they are encountered by a prosector and students. Embalming fluid usually contains formaldehyde, phenol, Dettol, and glycerine which disinfect and kill pathogens within the cadaver. With exposure to embalming fluid, tissues and bodily fluids, such as blood, become fixed. Prosectors and students working with embalmed cadavers must always wear protective gloves, however this is more for protection against the harsh chemicals used in embalming such as formaldehyde and dettol which can cause moderate to severe skin irritation.
Every year, an estimated 342,900 women die from complications of pregnancy and childbirth, 99% of these deaths occur in developing countries. Worldwide, for every 100,000 live births, about 251 women die. In some industrialized countries such as the U.S, this is 13 deaths for every 100,000 live babies born with American women having a lifetime risk of 1 in 2,100 of dying from childbirth related complications. However, in some countries, such as Afghanistan up to 1,600 women die for every 100,000 live births and women have a 1 in 11 lifetime risk of maternal death.
Of the 120 known indigenous snake species in North America, only 20 are venomous to human beings, all belonging to the families Viperidae and Elapidae. However, in the United States, every state except Maine, Alaska, and Hawaii is home to at least one of 20 venomous snake species. Up to 95% of all snakebite-related deaths in the United States are attributed to the western and eastern diamondback rattlesnakes. Further, the majority of bites in the United States occur in the southwestern part of the country, in part because rattlesnake populations in the eastern states are much lower.
The last cases of smallpox occurred in an outbreak of two cases, one of which was fatal, in Birmingham, UK, in 1978. A medical photographer, Janet Parker, contracted the disease at the University of Birmingham Medical School and died on September 11, 1978. In light of this incident, all known stocks of smallpox were destroyed or transferred to one of two WHO reference laboratories which had BSL-4 facilities—the Centers for Disease Control and Prevention (CDC) in the United States and the State Research Center of Virology and Biotechnology VECTOR in Koltsovo, Russia. Since 1984, these two labs have been the only ones authorized by the WHO to hold stocks of live smallpox virus.
Botulinum toxin is the most acutely lethal toxin that is known. It is produced by the bacterium clostridium botulinum. It acts inside nerve terminals by decreasing the release of acetylcholine, blocking neuromuscular transmission and thereby causing flaccid muscular paralysis. As a result, the muscle is weakened for about 3 to 4 months.
The inland taipan is the most venomous snake in the world. Based on the median lethal dose value in mice, its venom, drop for drop, is by far the most toxic of any snake – much more so than even sea snakes – and it has the most toxic venom of any reptile when tested on human heart cell culture. Unlike most snakes, the inland taipan is a specialist mammal hunter so its venom is specially adapted to kill warm-blooded species. It is estimated that one bite possesses enough lethality to kill at least 100 fully grown men, and, depending on the nature of the bite, it has the potential to kill someone in as little as 30 to 45 minutes if left untreated. It is an extremely fast and agile snake that can strike instantly with extreme accuracy, often striking multiple times in the same attack, and it envenoms in almost every case.
2,974 victims were confirmed to have died in the initial attacks; this includes Sneha Anne Philip, a doctor, who in 2008 was ruled to have died on 9/11. In 2007, the New York City medical examiner's office began to add people who died of illnesses caused by exposure to dust from the site to the official death toll. The first such victim was a woman, a civil rights lawyer, who had died from a chronic lung condition in February 2002. In September 2009, the office added a man who died in October 2008, and in 2011, a male accountant who had died in December 2010. This raises the number of victims at the World Trade Center site to 2,753, and the overall 9/11 death toll to 2,996.
The route west was arduous and fraught with many dangers, but the number of deaths on the trail is not known with any precision; there are only wildly varying estimates. Estimating is difficult because of the common practice of burying people in unmarked graves that were intentionally disguised to avoid their being dug up by animals or Indians. Graves were often put in the middle of a trail and then run over by the livestock to make them difficult to find. Disease was the main killer of trail travelers; cholera killed up to 3 percent of all travelers in the epidemic years from 1849 to 1855.
The worst of the 20th century influenza pandemics was the 1918 pandemic, where between 20-40 percent of the world’s population became ill between 40-100 million people died. More people died of the so-called Spanish flu (caused by the H1N1 viral strain) pandemic in the single year of 1918 than during all four-years of the Black Death. The pandemic had devastating effects as disease spread along trade and shipping routes and other corridors of human movement until it had circled the globe. InIndia, the mortality rate reached 50 per 1,000 population. Arriving during the closing phase of the World War I, the pandemic impacted mobilized national armies. Half of U.S. soldiers who died in the "Great War," for example, were victims of influenza. It is estimated that almost ¾ of a million Americans died during the pandemic. In part, the death toll during the pandemic was caused by viral pneumonia characterized by extensive bleeding in the lungs resulting in suffocation. Many victims died within 48 hours of the appearance of the first symptom. It was not uncommon for people who appeared to be quite healthy in the morning to have died by sunset. Among those who survived the first several days, however, many died of secondary bacterial pneumonia. It has been argued that countless numbers of those who expired quickly from the disease were co-infected with tuberculosis, which would explain the notable plummet in TB cases after 1918.
Sewing needles have been dated to at least 50,000 years ago (Denisova Cave, Siberia) – and uniquely associated with a human species other than modern humans, i.e. H. Denisova/H. Altai. The oldest possible example is 60,000 years ago, a needlepoint (missing stem and eye) found in Sibudu Cave, South Africa. Other early examples of needles dating from 41,000-15,000 years ago are found in multiple locations, e.g. Slovenia, Russia, China, Spain, and France.
The boomslang's venom is the most potent of all rear-fanged snakes in the world based on LD50. Although its venom may be more potent than some vipers and elapids, it causes fewer fatalities owing to various factors (for example, the fangs' effectiveness is not high compared with many other snakes: the venom dose delivered is low, and boomslangs are generally less aggressive in comparison to other venomous snakes such as cobras and mambas).
Many professions are at risk of needlestick injury including law enforcement, waste collectors, laborers, and agricultural workers. There is no standard system for collecting and tracking needlestick injuries in the community, which makes it difficult to measure the full impact of this problem. Law enforcement workers, like healthcare workers, under-report needlestick injuries. In San Diego, 30% of police reported needle sticks. A study of 1,333 police officers in the Denver Police Department found that only 43.4% reported a needlestick injury they received; 42% of which occurred during their evening shift. Most of the needlestick injuries experienced by these workers occurred in their first 5 years of employment. In New York City, a study found a rate of 38.7 exposures (needlesticks and human bites) per 10,000 police officers.
The psychological effects of occupational needlestick injuries can include health anxiety, anxiety about disclosure or transmission to a sexual partner, trauma-related emotions, and depression. These effects can cause self-destructive behavior or functional impairment in relationships and daily life. This is not mitigated by knowledge about disease transmission or PEP. Though some affected people have worsened anxiety during repeated testing, anxiety and other psychological effects typically abate after testing is complete. A minority of people affected by needlestick injuries may have lasting psychological effects, including post-traumatic stress disorder.
In the United States, approximately half of all needlestick injuries affecting health care workers are not reported, citing the long reporting process and its interference with work as their reason for not reporting an incident. The availability of hotlines, witnesses, and response teams can increase the percentage of reports. Physicians are particularly likely to leave a needlestick unreported, citing worries about loss of respect or a low risk perception. Low risk perception can be caused by poor knowledge about risk, or an incorrect estimate of a particular patient's risk. Surveillance systems to track needlestick injuries include the National Surveillance System for Healthcare Workers (NaSH), a voluntary system in the northeastern United States, and the Exposure Prevention Information Network (EPINet), a recording and tracking system that also gathers data.
A needlestick injury, percutaneous injury, or percutaneous exposure incident or sharps injury is the penetration of the skin by a needle or other sharp object, which has been in contact with blood, tissue or other body fluids before the exposure. Even though the acute physiological effects of a needlestick injury are generally negligible, these injuries can lead to transmission of blood-borne diseases, placing those exposed at increased risk of contracting infectious diseases, such as hepatitis B (HBV), hepatitis C (HCV), and the human immunodeficiency virus (HIV). Among healthcare workers and laboratory personnel worldwide, more than 25 blood-borne viruses have been reported to be caused by needlestick injuries. In addition to needlestick injuries transmission of these viruses can also occur as a result of contamination of the mucous membranes, such as those of the eyes, with blood or body fluids but needlestick injuries make up more than 80% of all percutaneous exposure incidents in the United States. Various other occupations are also at increased risk of needlestick injury, including law enforcement, laborers, tattoo artists, food preparers, and agricultural workers.