Instruct: Given a question, retrieve passages that answer the question.
Query: Who is the founder of modern anatomy?
Andreas Vesalius (; 31 December 1514 – 15 October 1564) was a 16th-century Flemish anatomist, physician, and author of one of the most influential books on human anatomy, "De humani corporis fabrica" ("On the Fabric of the Human Body"). Vesalius is often referred to as the founder of modern human anatomy. He was born in Brussels, which was then part of the Habsburg Netherlands. He was professor at the University of Padua and later became Imperial physician at the court of Emperor Charles V.
The history of biochemistry can be said to have started with the ancient Greeks who were interested in the composition and processes of life, although biochemistry as a specific scientific discipline has its beginning around the early 19th century. Some argued that the beginning of biochemistry may have been the discovery of the first enzyme, diastase (today called amylase), in 1833 by Anselme Payen, while others considered Eduard Buchner's first demonstration of a complex biochemical process alcoholic fermentation in cell-free extracts to be the birth of biochemistry. Some might also point to the influential work of Justus von Liebig from 1842, "Animal chemistry, or, Organic chemistry in its applications to physiology and pathology", which presented a chemical theory of metabolism, or even earlier to the 18th century studies on fermentation and respiration by Antoine Lavoisier.
Human dissections were carried out by the Greek physicians Herophilus of Chalcedon and Erasistratus of Chios in the early part of the third century BC. During this period, the first exploration into full human anatomy was performed rather than a base knowledge gained from 'problem-solution' delving. While there was a deep taboo in Greek culture concerning human dissection, there was at the time a strong push by the Ptolemaic government to build Alexandria into a hub of scientific study. For a time, Roman law forbade dissection and autopsy of the human body, so physicians had to use other cadavers. Galen, for example, dissected the Barbary macaque and other primates, assuming their anatomy was basically the same as that of humans.
In 1820, Justinus Kerner, a small-town German medical officer and romantic poet, gave the first complete description of clinical botulism based on extensive clinical observations of so-called “sausage poisoning”. Following experiments on animals and on himself, he concluded that the toxin acts by interrupting signal transmission in the somatic and autonomic motor systems, without affecting sensory signals or mental functions. He observed that the toxin develops under anaerobic conditions, and can be lethal in minute doses. His prescience in suggesting that the toxin might be used therapeutically earned him recognition as the pioneer of modern botulinum toxin therapy.
The supply of printed anatomy books from Italy and France led to an increased demand for human cadavers for dissections. Since few bodies were voluntarily donated for dissection, royal charters were established which allowed prominent universities to use the bodies of hung criminals for dissections. However, there was still a shortage of bodies that could not accommodate for the high demand of bodies. Until the middle of the 18th century, there was a quota of ten cadavers for each the Royal College of Physicians and the Company of Barber Surgeons, the only two groups permitted to perform dissections. During the first half of the 18th century, William Cheselden challenged the Company of Barber Surgeon’s exclusive rights on dissections. He was the first to hold regular anatomy lectures and demonstrations. He also wrote "The Anatomy of the Humane Body," a student handbook of anatomy. In 1752, the rapid growth of medical schools in England and the pressing demand for cadavers led to the passage of the Murder Act. This allowed medical schools in England to legally dissect bodies of executed murderers for anatomical education and research and also aimed to prevent murder. To further increase the supply of cadavers, the government increased the number of crimes in which hanging was a punishment. Although the number of cadavers increased, it was still not enough to meet the demand of anatomical and medical training.
Following the footsteps of the Enlightenment rationalism and experimentalism, Germany began to see the rise of agricultural experiment stations, indicating the beginnings of an attempt to merge traditional agronomy with analytical chemistry. In 1840, Justus von Liebig, an influential German chemist and professor at the University of Giessen, published his book "Organic Chemistry in its Application to Agriculture and Physiology". Liebig theorized that nitrogen and trace minerals from soil erosion were essential to plant nutrition, and, from this analytical chemistry perspective, simplified agriculture to a series of chemical reactions. While Liebig’s work inspired a generation of analytical agricultural chemists interested in fundamental questions of plant nutrition, founders of early German agricultural experiment stations did not solely seek to pursue questions of soil chemistry, but rather sought to bridge the gap between the two fields of agriculture and chemistry.
Marie Jean Pierre Flourens (13 April 1794 – 6 December 1867), father of Gustave Flourens, was a French physiologist, the founder of experimental brain science and a pioneer in anesthesia. Through the study of ablations on animals, he was the first to prove that the mind was located in the brain, not the heart.
Frederick II (1194-1250), the Holy Roman emperor, ruled that any that were studying to be a physician or a surgeon must attend a human dissection, which would be held no less than every five years. Some European countries began legalizing the dissection of executed criminals for educational purposes in the late 13th and early 14th centuries. Mondino de Luzzi carried out the first recorded public dissection around 1315. At this time, autopsies were carried out by a team consisting of a Lector, who lectured, the Sector, who did the dissection, and the Ostensor who pointed to features of interest.
Credit for developing cell theory is usually given to two scientists: Theodor Schwann and Matthias Jakob Schleiden. While Rudolf Virchow contributed to the theory, he is not as credited for his attributions toward it. In 1839, Schleiden suggested that every structural part of a plant was made up of cells or the result of cells. He also suggested that cells were made by a crystallization process either within other cells or from the outside. However, this was not an original idea of Schleiden. He claimed this theory as his own, though Barthelemy Dumortier had stated it years before him. This crystallization process is no longer accepted with modern cell theory. In 1839, Theodor Schwann states that along with plants, animals are composed of cells or the product of cells in their structures. This was a major advancement in the field of biology since little was known about animal structure up to this point compared to plants. From these conclusions about plants and animals, two of the three tenets of cell theory were postulated.
Michigan State University, Kellogg Biological Station: Eminent Ecologist (1992)
Fechner, along with Wilhelm Wundt and Hermann von Helmholtz, is recognized as one of the founders of modern experimental psychology. His clearest contribution was the demonstration that because the mind was susceptible to measurement and mathematical treatment, psychology had the potential to become a quantified science. Theorists such as Immanuel Kant had long stated that this was impossible, and that therefore, a science of psychology was also impossible.
The two men finally in person in 1842. Humboldt died in 1859, sixth months before the first edition of "On the Origin of Species" was published. In letters to his close friend Joseph Dalton Hooker, Darwin reflected that his "whole course of life" was due to having read Humboldt's "Personal Narrative" and conclusively praised Humboldt as the "Greatest scientific traveller who ever lived."
Ernst Heinrich Weber (24 June 1795 – 26 January 1878) was a German physician who is considered one of the founders of experimental psychology. He was an influential and important figure in the areas of physiology and psychology during his lifetime and beyond. His studies on sensation and touch, along with his emphasis on good experimental techniques gave way to new directions and areas of study for future psychologists, physiologists, and anatomists.
Euclid (; – "Eukleídēs", ; fl. 300 BC), sometimes given the name Euclid of Alexandria to distinguish him from Euclides of Megara, was a Greek mathematician, often referred to as the "founder of geometry" or the "father of geometry". He was active in Alexandria during the reign of Ptolemy I (323–283 BC). His "Elements" is one of the most influential works in the history of mathematics, serving as the main textbook for teaching mathematics (especially geometry) from the time of its publication until the late 19th or early 20th century. In the "Elements", Euclid deduced the theorems of what is now called Euclidean geometry from a small set of axioms. Euclid also wrote works on perspective, conic sections, spherical geometry, number theory, and rigor.
Wilhelm Maximilian Wundt (; ; 16 August 1832 – 31 August 1920) was a German physician, physiologist, philosopher, and professor, known today as one of the founding figures of modern psychology. Wundt, who noted psychology as a science apart from philosophy and biology, was the first person ever to call himself a psychologist. He is widely regarded as the "father of experimental psychology". In 1879, Wundt founded the first formal laboratory for psychological research at the University of Leipzig. This marked psychology as an independent field of study. By creating this laboratory he was able to establish psychology as a separate science from other disciplines. He also formed the first academic journal for psychological research, "Philosophische Studien" (from 1881 to 1902), set up to publish the Institute's research.
One of the greatest Persian medics was Avicenna, also known as Ibn Sina, who lived from 980AD to 1037AD. His works included a comprehensive collection and systematisation of the fragmentary and unorganised Greco-Roman medical literature that had been translated Arabic by that time, augmented by notes from his own experiences. One of his books, "Al-Qānūn fī aṭ-Ṭibb" (The Canon of Medicine) has been called the most famous single book in the history of medicine in both East and West. Avicenna excelled in the logical assessment of conditions and comparison of symptoms and took special note of analgesics and their proper use as well as other methods of relieving pain, including massage.
Human cadavers have been dissected by physicians since at least the 3rd century BC, but throughout history, prevailing religious views on the desecration of corpses often meant that such work was performed in secrecy. The Christian church forbade human dissection until the 14th century, when the first recorded anatomisation of a cadaver took place in Bologna. Until then, anatomical research was limited to the dissection of animals. In Britain, human dissection was proscribed by law until 1506, when King James IV of Scotland gave royal patronage to the Barber-Surgeons of Edinburgh, allowing them to dissect the "bodies of certain executed criminals". England followed in 1540, when Henry VIII gave patronage to the Company of Barber-Surgeons, allowing them access to four executed felons each year (Charles II later increased this to six felons each year). Elizabeth I granted the College of Physicians the right to anatomise four felons annually in 1564.
In 1895 (seventy-five years later), Émile van Ermengem, professor of bacteriology and a student of Robert Koch, correctly described "Clostridium botulinum" as the bacterial source of the toxin. Thirty-four attendees at a funeral were poisoned by eating partially salted ham, an extract of which was found to cause botulism-like paralysis in laboratory animals. Van Ermengem isolated and grew the bacterium, and described its toxin, which was later purified by P Tessmer Snipe and Hermann Sommer.
Cell, developmental, and reproductive biology have been a central part of the MBL's programs since the 1890s. Important discoveries in these fields at the MBL reach back to 1899, when Jacques Loeb demonstrated artificial parthenogenesis in sea urchin eggs; to 1905, when Edwin Grant Conklin first identified egg cytoplasmic regions that are programmed to form certain tissues or organs; to 1916, when Frank Rattray Lillie identified circulating hormones that influence sexual differentiation (Lillie, 1944). In the MBL's first two decades, cytologists Edmund Beecher Wilson, Nettie Stevens and others made connections between the chromosomes and Mendelian heredity, while Wilson's colleague at both the MBL and Columbia University, Thomas Hunt Morgan, launched the field of experimental genetics (Pauly, 2000:158). Keith R. Porter, considered by many to be a founder of modern cell biology due to his pioneering work on the fine structure of cells, including the discovery of microtubules, carried out research at the MBL starting in 1937 and directed the laboratory from 1975-77 (Barlow et al., 1993: 95-115).
The first use of the term "anthropology" in English to refer to a natural science of humanity was apparently in Richard Harvey's 1593 "Philadelphus, a defense of the legend of Brutus in British history", which, includes the passage: "Genealogy or issue which they had, Artes which they studied, Actes which they did. This part of History is named Anthropology."
Russian chemistry professor Dmitri Mendeleev and German chemist Julius Lothar Meyer independently published their periodic tables in 1869 and 1870, respectively. Mendeleev's table was his first published version; that of Meyer was an expanded version of his (Meyer's) table of 1864. They both constructed their tables by listing the elements in rows or columns in order of atomic weight and starting a new row or column when the characteristics of the elements began to repeat.
Walter Pagel comments that Aristotle "perceptibly influenced" the founders of modern zoology, the Swiss Conrad Gessner with his 1551–1558 "Historiae animalium", the Italian Ulisse Aldrovandi (1522–1605), the French Guillaume Rondelet (1507–1566), and the Dutch Volcher Coiter (1534–1576), while his methods of looking at time series and making use of comparative anatomy assisted the Englishman William Harvey in his 1651 work on embryology.
One of the founders of modern otology, Schwartze made a particular study of the anatomy of the ear and improved the methods of paracentesis on the tympanic membrane and of the opening of inflamed apophyses of the middle ear.
Peter Franzevich Lesgaft () (21 September 1837 – 1909) was a Russian teacher, anatomist, physician and social reformer. He was the founder of the modern system of physical education and medical-pedagogical control in physical training, one of founders of theoretical anatomy. Lesgaft National State University of Physical Education, Sport and Health in St. Petersburg is named after him.
Unity and integrity of all organs in human body was the basis of Peter Lesgaft system of the pointed exercises for both physical development and intellectual, moral and aesthetic education.
In Ancient Greece, the "Hippocratic Corpus" described the anatomy of the skeleton and muscles. The 2nd century physician Galen of Pergamum compiled classical knowledge of anatomy into a text that was used throughout the Middle Ages.
In the Renaissance, Andreas Vesalius (1514–1564) pioneered the modern study of human anatomy by dissection, writing the influential book "De humani corporis fabrica". Anatomy advanced further with the invention of the microscope and the study of the cellular structure of tissues and organs. Modern anatomy uses techniques such as magnetic resonance imaging, computed tomography, fluoroscopy and ultrasound imaging to study the body in unprecedented detail.