Instruct: Given a question, retrieve documents that can help answer the question.
Query: Who built the Topkapi palace?
After the conquest of Istanbul by Mehmed the Conqueror at 1453, construction of the Topkapı Palace was started in the year 1460 and completed in 1478. The palace was built upon a 700,000 square meter area on an Eastern Roman Acropolis located on the Istanbul Peninsula between the Sea of Marmara, Bosphorus and the Golden Horn. Topkapı Palace was the administrative, educational, and art center of the Empire for nearly four hundred years from Mehmed the Conqueror until Sultan Abdulmecid who was the thirty-first Sultan. Although Topkapi Palace was abandoned by the Ottoman Dynasty by moving to the Dolmabahçe Palace in the middle of the 19th century, Topkapı Palace retained its importance.
The cross on top of the dome has been replaced by the conquering Ottomans with the symbol of Islam, the crescent moon.
After the Ottoman conquest of Constantinople in 1453 by Mehmed II, the church was enclosed inside the walls of the Topkapi palace. The Janissaries used the church as an arsenal until 1826. It was also used as a warehouse for military equipment and repository for trophies of arms and military regalia taken by the Turks. During the reign of Sultan Ahmet III (1703–1730) it was converted into the National Military Museum in 1726.
The post of the Kizlar Agha was created in the reign of Murad III (ruled 1574–1595) in 1574, with the Ethiopian Mehmed Agha as its first occupant. Until then, the Ottoman palace had been dominated by the white eunuchs, chiefly drawn from the Christian populations of the Balkans or the Caucasus. The 16th century, however, saw a rapid rise of the population of the Topkapi Palace, including among eunuchs, whose numbers rose from 40 under Selim (r. 1512–1520) to over a thousand under Murad III. While black eunuchs had served alongside white eunuchs in the palace, by 1592, for reasons that are unclear, both a separation of roles as well as the ascendancy of the black eunuchs over the white ones had become established: white eunuchs were restricted to the supervision of the male pages ("içoğlan"), while black eunuchs took over the far more prestigious supervision of the private apartments of the Sultan and the palace women ("harem"). Consequently, the Chief Black Eunuch quickly eclipsed the "Chief White Eunuch" or Kapi Agha ("kapı ağası", "Agha of the Gate"), who had hitherto been the head of the palace personnel, and rose to become, in the words of the Orientalist C. E. Bosworth, "in practice the principal officer of the whole palace". At the height of the post's power in the 17th and 18th centuries, the Kizlar Agha was a vizier of the first rank ("with three horsetails") and came third in the state hierarchy, next only to the Empire's chief minister, the Grand Vizier, and the chief religious authority, the Sheikh ul-Islam.
Elizabeth Lipp (Melina Mercouri) visits Istanbul, where she sees a traveling fair featuring replicas of treasures from the Topkapı Palace. Next she cases the Topkapi, fascinated by the emerald-encrusted dagger of Sultan Mahmud I. Leaving Turkey, she recruits her ex-lover, Swiss master-criminal Walter Harper (Maximilian Schell), to plan a theft of the dagger. They engage Cedric Page (Robert Morley), master of all things mechanical; Giulio, "The Human Fly" (Gilles Ségal), a mute acrobat; and the burly Hans (Jess Hahn), who will provide the muscle needed for the job.
Constantinople (; ) was the capital city of the Roman/Byzantine Empire (330–1204 and 1261–1453), and also of the brief Crusader state known as the Latin Empire (1204–1261), until finally falling to the Ottoman Empire (1453–1923). It was reinaugurated in 324 from ancient Byzantium as the new capital of the Roman Empire by Emperor Constantine the Great, after whom it was named, and dedicated on 11 May 330. The city was located in what is now the European side and the core of modern Istanbul.
The establishment of Constantinople served as one of Constantine's most lasting accomplishments, shifting Roman power eastward as the city became a center of Greek culture and Christianity. Numerous churches were built across the city, including the Hagia Sophia which was built during the reign of Justinian the Great and remained the world's largest cathedral for a thousand years. Constantine also undertook a major renovation and expansion of the Hippodrome of Constantinople; accommodating tens of thousands of spectators, the hippodrome became central to civic life and, in the 5th and 6th centuries, the epicenter of episodes of unrest, including the Nika riots. Constantinople's location also ensured its existence would stand the test of time; for many centuries, its walls and seafront protected Europe against invaders from the east and the advance of Islam. During most of the Middle Ages, the latter part of the Byzantine era, Constantinople was the largest and wealthiest city on the European continent and at times the largest in the world.
The Taj Mahal (; , meaning "Crown of the Palaces") is an ivory-white marble mausoleum on the south bank of the Yamuna river in the Indian city of Agra. It was commissioned in 1632 by the Mughal emperor, Shah Jahan (reigned from 1628 to 1658), to house the tomb of his favourite wife, Mumtaz Mahal. It also houses the tomb of Shah Jahan, the builder. The tomb is the centerpiece of a complex, which includes a mosque and a guest house, and is set in formal gardens bounded on three sides by a crenellated wall.
Darius I built the greatest palace at Persepolis on the western side of platform. This palace was called the "Apadana". The King of Kings used it for official audiences. The work began in 518 BC, and his son, Xerxes I, completed it 30 years later. The palace had a grand hall in the shape of a square, each side long with seventy-two columns, thirteen of which still stand on the enormous platform. Each column is high with a square Taurus (bull) and plinth. The columns carried the weight of the vast and heavy ceiling. The tops of the columns were made from animal sculptures such as two-headed lions, eagles, human beings and cows (cows were symbols of fertility and abundance in ancient Iran). The columns were joined to each other with the help of oak and cedar beams, which were brought from Lebanon. The walls were covered with a layer of mud and stucco to a depth of 5 cm, which was used for bonding, and then covered with the greenish stucco which is found throughout the palaces.
While there is evidence that the hill was inhabited as far back as the fourth millennium BC, it was Pericles (c. 495 – 429 BC) in the fifth century BC who coordinated the construction of the site's most important present remains including the Parthenon, the Propylaia, the Erechtheion and the Temple of Athena Nike. The Parthenon and the other buildings were damaged seriously during the 1687 siege by the Venetians during the Morean War when gunpowder being stored in the Parthenon was hit by a cannonball and exploded.
In the mid-5th century BC, when the Athenian Acropolis became the seat of the Delian League and Athens was the greatest cultural centre of its time, Pericles initiated an ambitious building project that lasted the entire second half of the century. The most important buildings visible on the Acropolis today — the Parthenon, the Propylaia, the Erechtheion and the temple of Athena Nike — were erected during this period. The Parthenon was built under the general supervision of the artist Phidias, who also had charge of the sculptural decoration. The architects Ictinos and Callicrates began their work in 447 BC, and the building was substantially completed by 432, but work on the decorations continued until at least 431.
The Sacred seal, or "Mühr-ü Şerif" in Turkish, was reported by Tavernier, who said it was kept in a small ebony box in a niche cut in the wall by the foot of a divan in the relic room at Topkapi.
Muhammad was quite good with a bow, and appreciated the benefits of archery in sports and warfare. A recurved bow made of bamboo, and ascribed to Muhammad, is held in the Sacred Relics (Topkapı Palace) in the Chamber of the Sacred Relics in the Topkapi Museum in Istanbul.
Trump World Tower was briefly the tallest all-residential tower in the world, prior to the completion of the 21st Century Tower in Dubai (2003) and the Tower Palace 3 in Seoul (2004). The tallest of the handful of wholly residential towers completed to date by Donald Trump, it cost approximately US$300 million to construct. The penthouse on the top two floors of the structure which totaled 20,000 square feet (1,858 m²) was priced at $58 million; however, after failing to sell for years, it was split into four different units.
The Old or Grand Bazaar "(Çarshia e Madhe)" in Gjakova is the oldest bazaar in Kosovo, and it served as an Ottoman trading centre and heart of the town economy. It suffered damage during the Kosovo War but has since been renovated. The Hadum Mosque, built in the 16th century, lies by the bazaar, and includes a highly decorated graveyard, where the town notables were buried. Within the mosque complex were the "hamam" which was destroyed in 2008, the "Old library" from 1671, damaged in the Kosovo War, and also a "meytepi" from 1777. The Bazaar is linked to the city centre, just five minutes away via the Islam-Beg Bridge. The bazaar covers an area of about and the length of its main road is 1 km, with about 500 shops situated along it. It is, however, still home to an active mosque, several türbes, and a clocktower.
Pergamon's other notable structure is the great temple of the Egyptian gods Isis and/or Serapis, known today as the "Red Basilica" (or "Kızıl Avlu" in Turkish), about south of the Acropolis at (39 7' 19" N, 27 11' 1" E). It consists of a main building and two round towers within an enormous "temenos" or sacred area. The temple towers flanking the main building had courtyards with pools used for ablutions at each end, flanked by stoas on three sides. The forecourt of the Temple of Isis/Sarapis is still supported by the Pergamon Bridge, the largest bridge substruction of antiquity.
The Winter Palace () was the official residence of the Russian Emperors from 1732 to 1917. Today, the palace and its precincts form the Hermitage Museum. Situated between Palace Embankment and Palace Square, in Saint Petersburg, adjacent to the site of Peter the Great's original Winter Palace, the present and fourth Winter Palace was built and altered almost continuously between the late 1730s and 1837, when it was severely damaged by fire and immediately rebuilt. The storming of the palace in 1917, as depicted in Soviet paintings and Eisenstein's 1927 film "October", became an iconic symbol of the Russian Revolution.
Gjakova is mentioned as a city for the first time in 1662, by the Ottoman Turkish traveler Evliya Çelebi, who described it as a flourishing and attractive town consisting of 2,000 houses, all built of stone with roofs and gardens. 
Public buildings were suited on a broad plain and included two richly adorned Congregational mosques, several prayer-houses, some khans with leaden roofs, a delightful bathhouse, and about 300 shops like nightingale-nests.
The historical monuments in Gjakova, western Kosovo, are divided into three main categories based on their cultural, religious, and social context. In 1574, the Hadum Mosque was built on Jak Vula's property, laying the foundation of the city. The core part of the town was created between the Krena River to the east and Cabrati hill to the west. Around the cornerstone of the town, the Old Bazaar, the center of trade and craftsmanship, was created. By 1900, the bazaar housed around 1,000 businesses. Numerous bridges were built to enable trade caravans to cross the neighboring rivers. With the fast development of trade in the city, several inns were built to host visitors. Because of its ancient origins, and rapid economic development, Gjakova is of historical importance.
The palace is named for the 1704 Battle of Blenheim, and thus ultimately after Blindheim (also known as Blenheim) in Bavaria. It was originally intended to be a reward to John Churchill, 1st Duke of Marlborough for his military triumphs against the French and Bavarians in the War of the Spanish Succession, culminating in the Battle of Blenheim. The land was given as a gift, and construction began in 1705, with some financial support from Queen Anne. The project soon became the subject of political infighting, with the Crown cancelling further financial support in 1712, Marlborough's three-year voluntary exile to the Continent, the fall from influence of his duchy and lasting damage to the reputation of the architect Sir John Vanbrugh.
With King John II's death, in 1495, his cousin, Manuel I, Duke of Beja and Viseu, succeeded King John II as King Manuel I of Portugal. King Manuel I's personal monopoly on the spice trade allowed the King to be a great patron of the arts, constructing numerous palaces, convents, and churches throughout the country. King Manuel I took a great interest in Évora, establishing his court there on various occasions. From 1502 to 1520, King Manuel I ordered a vast series of renovations, constructions, and enlargements. During the Manueline Campaigns, as the works are collectively known as, the palace grew to one of the largest palaces in Iberia. Through architects Martim Lourenço, Álvaro Anes, and António de Lagoa the Manuline Campaign saw the construction of Couto Hall, the Wing of the Infantes, an infirmary, the Royal Gardens and Hunting Grounds, the Royal Library, and the Gallery of Dames, which is the only part of the palace to survive to present day. Alongside expansion of the palace, King Manuel I also renovated the existing parts of the palace, remodeling the Queen's Hall, the servants quarters, and the Rossio of the Palace. In 1519, King Manuel I ordered architect André Pires to turn the plain Hall of Ambassadors into a Manueline Throne Room, which would direct itself towards the Palace Rossio.
Constantinople became established in the ecclesiastical hierarchy at the Council of Constantinople in 381. Second only to Rome, the legendary origins of the Patriarchate of Constantinople go back to St. Andrew, Metrophanes and Alexander of Constantinople. Constantinople's primacy over the Patriarchates of Alexandria and Antioch was reaffirmed at the Council of Chalcedon in 481, after which the papacy in Rome supported Constantinople in its dispute with Alexandria over monophysitism. Later, when Rome sought to assert its primacy over Byzantium, the Eastern Orthodox church developed the doctrine of pentarchy as a response.
According to an identifying document at the Hagia Sophia in Istanbul, Moses's staff would supposedly be on display today at the Topkapı Palace, Istanbul, Turkey. The Topkapi Palace holds other reputedly holy relics, most notably those attributed to the Islamic prophet, Muhammad. (Such as his bow, his sword, his footprint, and even a tooth.) Topkapı Palace was officially designated a museum in 1924, and the holy relics were placed on public view on 31 August 1962. It is said that Sultan Selim I (1512–1520) brought the holy relics to Topkapi Palace after conquering Egypt in 1517.
The second room houses the Topkapı Dagger. The golden hilt is ornamented with three large emeralds, topped by a golden watch with an emerald lid. The golden scabbard is covered with diamonds and enamel. In 1747, the Sultan Mahmud I had this dagger made for Nader Shah of Persia, but the Shah was assassinated in connection with a revolt before the emissary had left the Ottoman Empire's boundaries. This dagger gained more fame as the object of the heist depicted of the film "Topkapi". In the middle of the second room stands the walnut throne of Ahmed I, inlaid with nacre and tortoise shell, built by Sedekhar Mehmed Agha. Below the baldachin hangs a golden pendant with a large emerald. The next displays show the ostentatious aigrettes of the sultans and their horses, studded with diamonds, emeralds and rubies. A jade bowl, shaped like a vessel, was a present of Czar Nicholas II of Russia.
Following the end of the Ottoman Empire in 1923, Topkapı was transformed into a museum by a government decree dated April 3, 1924. The Topkapı Palace Museum is administered by the Ministry of Culture and Tourism. The palace complex has hundreds of rooms and chambers, but only the most important are accessible to the public today, including the Ottoman imperial harem and the treasury, called "hazine" where the Spoonmaker's Diamond and Topkapi Dagger are on display. The museum collection also includes Ottoman clothing, weapons, armor, miniatures, religious relics, and illuminated manuscripts like the Topkapi manuscript. The complex is guarded by officials of the ministry as well as armed guards of the Turkish military. Topkapı Palace is part the Historic Areas of Istanbul, a group of sites in Istanbul that were added to the UNESCO World Heritage Site in 1985.
The enzyme belongs to the group of oxidoreductases according to the EC classification and is dependent on FAD as cofactor, thus it was classified as an external flavoprotein monooxygenase (designated as type E). It forms a two-component system with a reductase (StyB, StyA2B). The reductase utilizes solely NADH to reduce the FAD, which is then transferred to the styrene monooxygenase (StyA, StyA1). Two types of that enzyme are described so far: StyA/StyB (designated E1), first described from "Pseudomonas" species, and StyA1/StyA2B (designated E2), first described from Actinobacteria. The E1-type is more abundant in nature and comprises a single monooxygenase (StyA) supported by a single reductase (StyB), whereas the E2-type has a major monooxygenase (StyA1) which is supported by fusion protein of a monooxygenase and reductase (StyA2B). The latter one is the source of reduced FAD for the monooxygenase subunits and has some side activity as a monooxygenase. So far all styrene monooxygenases perform enantioselective epoxidations of styrene and chemically analogous compounds, which makes them interesting for biotechnological applications.