Instruct: Given a question, retrieve relevant passages that can help answer the question.
Query: How long is the large intestine in humans?
The large intestine also called the colon, consists of the cecum, rectum, and anal canal. It also includes the appendix, which is attached to the cecum. The colon is further divided into:
The main function of the large intestine is to absorb water.
The area of the large intestinal mucosa of an adult human is about 2 m.
The jejunum lies between the duodenum and the ileum and is considered to start at the suspensory muscle of the duodenum, a location called the duodenojejunal flexure. The division between the jejunum and ileum is not anatomically distinct due to the fact that in adult humans, the small intestine is usually 6-7m long, about two-fifths of which (2.5 m) is the jejunum.
In the human body at birth, there are over 270 bones, but many of these fuse together during development, leaving a total of 206 separate bones in the adult, not counting numerous small sesamoid bones. The largest bone in the body is the femur or thigh-bone, and the smallest is the stapes in the middle ear.
The pylorus, the lowest section of the stomach which attaches to the duodenum via the pyloric canal, contains countless glands which secrete digestive enzymes including gastrin. After an hour or two, a thick semi-liquid called chyme is produced. When the pyloric sphincter, or valve opens, chyme enters the duodenum where it mixes further with digestive enzymes from the pancreas, and then passes through the small intestine, where digestion continues. When the chyme is fully digested, it is absorbed into the blood. 95% of absorption of nutrients occurs in the small intestine. Water and minerals are reabsorbed back into the blood in the colon of the large intestine, where the environment is slightly acidic. Some vitamins, such as biotin and vitamin K produced by bacteria in the gut flora of the colon are also absorbed.
Unlike kangaroos and eucalyptus-eating possums, koalas are hindgut fermenters, and their digestive retention can last for up to 100 hours in the wild, or up to 200 hours in captivity. This is made possible by the extraordinary length of their caecum— long and in diameter—the largest proportionally of any animal. Koalas can select which food particles to retain for longer fermentation and which to pass through. Large particles typically pass through more quickly, as they would take more time to digest. While the hindgut is proportionally larger in the koala than in other herbivores, only 10% of the animal's energy is obtained from fermentation. Since the koala gains a low amount of energy from its diet, its metabolic rate is half that of a typical mammal, although this can vary between seasons and sexes. The koala conserves water by passing relatively dry faecal pellets high in undigested fibre, and by storing water in the caecum.
Constipation is the most common chronic gastrointestinal disorder in adults. Depending on the definition employed, it occurs in 2% to 20% of the population. It is more common in women, the elderly and children. Specifically constipation with no known cause affects females more often affected than males. The reasons it occurs more frequently in the elderly is felt to be due to an increasing number of health problems as humans age and decreased physical activity.Since ancient times different societies have published medical opinions about how health care providers should respond to constipation in patients. In various times and places, doctors have made claims that constipation has all sorts of medical or social causes. Doctors in history have treated constipation in reasonable and unreasonable ways, including use of a spatula mundani.
Most food digestion takes place in the small intestine. Segmentation contractions act to mix and move the chyme more slowly in the small intestine allowing more time for absorption (and these continue in the large intestine). In the duodenum, pancreatic lipase is secreted together with a co-enzyme, colipase to further digest the fat content of the chyme. From this breakdown, smaller particles of emulsified fats called chylomicrons are produced. There are also digestive cells called enterocytes lining the intestines (the majority being in the small intestine). They are unusual cells in that they have villi on their surface which in turn have innumerable microvilli on their surface. All these villi make for a greater surface area, not only for the absorption of chyme but also for its further digestion by large numbers of digestive enzymes present on the microvilli.
Yellow-footed tortoises are a large species – fifth-largest overall and third-largest mainland species, after the Aldabra giant tortoise ("Aldabrachelys gigantea"), Galapagos giant tortoise ("Chelonoidis nigra"), African spurred tortoise, and Asian forest tortoise. Typical sizes average 40 cm (15.75 in), but much larger specimens are common. The largest know specimen is a female that was 94 cm (37 in) long. They closely resemble the red-footed tortoise, and can sometimes be difficult to tell apart, especially as a preserved specimen, which led to quite a bit of confusion over the names and ranges.
In the small intestine, the pH becomes crucial; it needs to be finely balanced in order to activate digestive enzymes. The chyme is very acidic, with a low pH, having been released from the stomach and needs to be made much more alkaline. This is achieved in the duodenum by the addition of bile from the gall bladder combined with the bicarbonate secretions from the pancreatic duct and also from secretions of bicarbonate-rich mucus from duodenal glands known as Brunner's glands. The chyme arrives in the intestines having been released from the stomach through the opening of the pyloric sphincter. The resulting alkaline fluid mix neutralises the gastric acid which would damage the lining of the intestine. The mucus component lubricates the walls of the intestine.
The digestive tract begins slightly behind the head, the mouth lying on the underside a little way from the frontmost point of the body. Here, prey can be mechanically dismembered by the mandibles with their covering of fine toothlets. Two salivary glands discharge via a common conductor into the subsequent "throat", which makes up the first part of the front intestine. The saliva that they produce contains mucus and hydrolytic enzymes, which initiate in and outside the mouth digestion. Historically, the salivary glands probably evolved from the waste-elimination organs known as nephridia, which are found homologously in the other body segments. The throat itself is very muscular, serving to absorb the partially liquified food and to pump it, via the oesophagus, which forms the rear part of the front intestine, into the central intestine. Unlike the front intestine, this is not lined with a cuticula but instead consists only of a single layer of epithelial tissue, which does not exhibit conspicuous indentation as is found in other animals. On entering the central intestine, food particles are coated with a mucus-based peritrophic membrane, which serves to protect the lining of the intestine from damage by sharp-edged particles. The intestinal epithelium secretes further digestive enzymes and absorbs the released nutrients, although the majority of digestion has already taken place externally or in the mouth. Indigestible remnants arrive in the rear intestine, or rectum, which is once again lined with a cuticula and which opens at the anus, located on the underside near to the rear end.
In human anatomy, the greater pancreatic artery (great pancreatic artery or arteria pancreatica magna), is the largest artery that supplies the pancreas. It arises from the splenic artery.
Fecal incontinence (FI), also known as anal incontinence, or in some forms encopresis, is a lack of control over defecation, leading to involuntary loss of bowel contents—including flatus (gas), liquid stool elements and mucus, or solid feces. FI is a sign or a symptom, not a diagnosis. Incontinence can result from different causes and might occur with either constipation or diarrhea. Continence is maintained by several interrelated factors, including the anal sampling mechanism, and usually there is more than one deficiency of these mechanisms for incontinence to develop. The most common causes are thought to be immediate or delayed damage from childbirth, complications from prior anorectal surgery (especially involving the anal sphincters or hemorrhoidal vascular cushions), altered bowel habits (e.g., caused by irritable bowel syndrome, Crohn's disease, ulcerative colitis, food intolerance, or constipation with overflow incontinence), and receptive anal sex. An estimated 2.2% of community dwelling adults are affected.
There were larger dinosaurs, but knowledge of them is based entirely on a small number of fragmentary fossils. Most of the largest herbivorous specimens on record were discovered in the 1970s or later, and include the massive titanosaur "Argentinosaurus huinculensis", which is the largest dinosaur known from uncontroversial evidence, estimated to have been and long. Some of the longest sauropods were those with exceptionally long, whip-like tails, such as the "Diplodocus hallorum" (formerly "Seismosaurus") and the 33- to 35-metre-long (108–115 ft) "Supersaurus". The tallest was the "Brachiosaurus".
This may occur when there is a large mass of feces in the rectum (fecal loading), which may become hardened (fecal impaction). Liquid stool elements are able to pass around the obstruction, leading to incontinence. Megarectum (enlarged rectal volume) and rectal hyposensitivity are associated with overflow incontinence. Hospitalized patients and care home residents may develop FI via this mechanism, possibly a result of lack of mobility, reduced alertness, constipating effect of medication and/or dehydration.
The brain of the domesticated cat is about long, and weighs . If a typical cat is taken to be long with a weight of , then the brain would be at 0.91% of its total body mass, compared to 2.33% of total body mass in the average human. Within the encephalization quotient proposed by Jerison in 1973, values above 1 are classified big brained, while values lower than 1 are small brained. The domestic cat is attributed a value of between 1–1.71 relative to human value that is 7.44–7.8. The largest brains in the Felidae family are those of the tigers in Java and Bali, of which the largest relative brain size within the "panthera" is the "tigris". It is debated whether there exists a causal relationship between brain size and intelligence in vertebrates. Correlations have been shown between these factors in a number of experiments. However, correlation does not imply causation. Most experiments involving the relevance of brain size to intelligence hinge on the assumption that complex behavior requires a complex (and therefore intelligent) brain; however, this connection has not been consistently demonstrated.
The largest living reptile, a representative of the order Crocodilia, is the saltwater crocodile ("Crocodylus porosus") of Southern Asia and Australia, with adult males being typically long. The largest confirmed saltwater crocodile on record was long, and weighed about . Unconfirmed reports of much larger crocodiles exist, but examinations of incomplete remains have never suggested a length greater than . A living specimen estimated at and has been accepted by the Guinness Book of World Records, but due to the difficulty of trapping and measuring a very large living crocodile, the accuracy of these dimensions has yet to be verified. A specimen caught alive in the Philippines in 2011 (now dead) was found to have measured in length.
Irritable bowel syndrome (IBS) is the most common of the functional gastrointestinal disorders. These are idiopathic disorders that the Rome process has helped to define.
This giant breed matures slowly in both mind and body, taking anywhere from 2 to 3 years. The objective in training this dog is for the owner to build trust through humane methods. As youngsters, they can be quite boisterous and they do require steady and reliable training to develop manners and physical self-control. As with all large, active working dogs, this breed should be well socialized early in life with other dogs and people, and be provided with regular activity and training.
Functional gastrointestinal disorders are very common. Globally, irritable bowel syndrome and functional dyspepsia alone may affect 16–26% of the population.
Tapeworms are endoparasites with numerous adaptations to enhance parasitic nutrition. Tapeworms live in the small intestine of humans, providing an ideal location to access a readily available, rich source of pre-digested nutrients. Since nutrients in the small intestine are plentiful and pre-digested by the host, tapeworms do not require a gut and instead have adaptations to maximise nutrient absorption. Tapeworms have a tegument that they use to absorb nutrients directly from the host small intestine by diffusion. They also have anatomical adaptations in the form of a scolex with hookers and suckers that they use to attach to the host small intestine wall, preventing the tapeworm from being egested following peristalsis. Tapeworms have a flattened body with microtriches to maximise the surface area available for nutrient absorption and they additionally have various transporter molecules. Tapeworms have to compete with the host epithelium for nutrients, so it is essential that they compete more efficiently for nutrients. They also secrete enzymes to enhance host digestive enzymes e.g. pancreatic α-amylase.
"Brontosaurus" was a large, long-necked quadrupedal animal with a long, whip-like tail, and forelimbs that were slightly shorter than its hindlimbs. The largest species, "B. excelsus", weighed up to and measured up to long from head to tail. For comparison, the current largest land animal, the average male African bush elephant is 3.20 m (10.5 ft) tall at the shoulder and has a body mass of 6,000 kg (13,228 lb) or 6.6 short tons.
"Fasciolopsis buski" is commonly called the giant intestinal fluke, because it is an exceptionally large parasitic fluke, and the largest known to parasitise humans. Its size is variable and a mature specimen might be as little as 2 cm long, but the body may grow to a length of 7.5 cm and a width of 2.5 cm. It is a common parasite of humans and pigs and is most prevalent in Southern and Southeastern Asia. It is a member of the family Fasciolidae in the order Plagiorchiida. The Echinostomida are members of the class Trematoda, the flukes. The fluke differs from most species that parasitise large mammals, in that they inhabit the gut rather than the liver as "Fasciola" species do. "Fasciolopsis buski" generally occupies the upper region of the small intestine, but in heavy infestations can also be found in the stomach and lower regions of the intestine. "Fasciolopsis buski" is the cause of the pathological condition fasciolopsiasis.
The human appendix averages 9 cm in length but can range from 2 to 20 cm. The diameter of the appendix is usually between 7 and 8 mm. The longest appendix ever removed was 26 cm long. The appendix is usually located in the lower right quadrant of the abdomen, near the right hip bone. The base of the appendix is located 2 cm beneath the ileocecal valve that separates the large intestine from the small intestine. Its position within the abdomen corresponds to a point on the surface known as McBurney's point.
The bacteria break down some of the fiber for their own nourishment and create acetate, propionate, and butyrate as waste products, which in turn are used by the cell lining of the colon for nourishment. No protein is made available. In humans, perhaps 10% of the undigested carbohydrate thus becomes available, though this may vary with diet; in other animals, including other apes and primates, who have proportionally larger colons, more is made available, thus permitting a higher portion of plant material in the diet. The large intestine produces no digestive enzymes — chemical digestion is completed in the small intestine before the chyme reaches the large intestine. The pH in the colon varies between 5.5 and 7 (slightly acidic to neutral).
The length of the small intestine can vary greatly, from as short as to as long as , also depending on the measuring technique used. The typical length in a living person is 3m-5m. The length depends both on how tall the person is and how the length is measured. Taller people generally have a longer small intestine and measurements are generally longer after death and when the bowel is empty.