Careful use of pain medication such as morphine or fentanyl can be used for analgesia. For example, naloxone is the antidote for opiates such as heroin or morphine. Opioids have pharmacologic actions resembling morphine and other components of opium. Its abuse liability is similar to morphine and less than oxycodone. Most of the licit morphine produced is used to make codeine by methylation. Hydromorphone is used as alternative to morphine. Freud also recommended cocaine as a cure for morphine addiction. The official cause of death was an overdose of morphine and alcohol. Pure morphine and heroin are both fine powders. He later started to consume painkillers, including morphine, and alcohol to help ease the pain. In 1879 cocaine began to be used to treat morphine addiction. Subcutaneous injections are highly effective in administering medications such as insulin, morphine, diacetylmorphine and goserelin. After the fight, Rutten tested positive for hydrocodone, morphine, and diphenhydramine. Diamorphine is produced from acetylation of morphine derived from natural opium sources. This is the reason that drugs such as morphine affect consciousness.