Most cultivated plants are produced by vegetative propagation. It occurs through vegetative reproductive spores, the conidia. Organs of plants can be divided into vegetative and reproductive. The result is that no separate vegetative and flowering lighting environment are needed. Plants have a number of mechanisms for asexual or vegetative reproduction. Fig plants can be propagated by seed or by vegetative methods. Cultivars have accomplished this desired plant through natural mutations resulting from vegetative multiplication. Both vegetative (asexual) and seed reproduction occur. Some plants were able to be propagated by vegetative cloning. Critically, "it is ingestion of toxin rather than spores or vegetative bacteria" that causes botulism. One spore forms per one vegetative bacterium. These can further develop into either vegetative or reproductive structures. Seeds from hybrids give rise to variable offspring, which may spread through vegetative propagation. Level 5 is comatose or persistent vegetative state. Patients in coma, vegetative, or minimally conscious state pose ethical challenges.