This gene encodes a protein located on a cytoplasmic membrane surface of intercellular tight junctions. This reorganization creates intercellular gaps in endothelial cells. Important molecules in these intercellular connections include N-cadherin, fibronectin, connexin and various integrins. These processes result in the release of intercellular signaling vesicles. The host plant exerts a control over the intercellular hyphal proliferation and arbuscule formation. Haustoria arise from intercellular hyphae, appressoria, or external hyphae. These proteins have functions in intra- and intercellular movement in host plants. Eukaryotic cells also produce M-CSF in order to combat intercellular viral infection. The cells interdigitate with each other, and project microvilli into the intercellular space. Exertional rhabdomyolysis results from damage to the intercellular proteins inside the sarcolemma. Underneath them, porous tissue creates a number of large intercellular spaces between cells. Meristematic cells are packed closely together without intercellular spaces. Interstitial matrix is present between various animal cells (i.e., in the intercellular spaces). Plants can also dehydrate their cells by moving water into intercellular spaces. The entrance of these host cells will differ between intercellular parasites.