Another common condition is gastric ulceration, peptic ulcers. Stomach diseases are often chronic conditions and include gastroparesis, gastritis, and peptic ulcers. Peptic ulcers may be treated with omeprazole. Tranexamic acid and antifibrinolytic agents are not useful in treating peptic ulcer disease. "Helicobacter pylori" is one of the major causative factors of peptic ulcer disease. They can have side effects of nausea, dyspepsia, peptic ulcer, and diarrhea. Heartburn or peptic ulcers can develop when these mechanisms fail. Milk-alkali syndrome declined in men after effective treatments for peptic ulcer disease arose. The RUQ may be painful or tender in hepatitis, cholecystitis, and peptic ulcer. Patients with bronchial asthma or a history of peptic ulcer need to be closely monitored. Human immune response toward the bacteria also determines the emergence of peptic ulcer disease. For instance, "Helicobacter pylori" causes 80% of peptic ulcers. Stomach pain is usually the first signal of a peptic ulcer. It is mainly used in the treatment of heartburn and peptic ulcers. This can happen with a sore throat, hemorrhages, diarrhea, and peptic ulcers.