The two antigens are antigen A and antigen B. IgE antibodies bind to antigens of allergens. Monoclonal antibodies are directed towards exactly defined antigens. Both IgM and IgG antibodies bind strongly with their complementary antigens. This allows the detection of antibodies to mitosis-specific antigens, such as centromere antibodies. Therefore, every B cell produces antibodies that bind specifically to different antigens. A simplified strategy is often employed to purify antibodies generated against peptide antigens. Molecular mimicry occurs when epitopes are shared between host antigens and "Streptococcus" antigens. GS-ANA are antibodies directed to granulocyte specific nuclear antigens. This results in different autoimmune diseases depending on the type of antigens and antibodies involved. The D antigen is the most immunogenic of all the non-ABO antigens. Thus, T cells help B cells make antibodies to the same foreign antigens. The predominant subclass of antibodies that acts against the antigens is IgG4. Immunogens are those antigens, termed immunogenic, capable of inducing an immune response. Immunoassays employ a variety of different labels to allow for detection of antibodies and antigens.