In bacteria, a similar strategy of employing an inactive zymogen or prezymogen is used. Asparagine endopeptidase is synthesized as an inactive zymogen. Enzymes like pepsin are created in the form of pepsinogen, an inactive zymogen. Plasmin generates active MMP-3 from its zymogen. Factor IX is produced as a zymogen, an inactive precursor. New cell wall material is formed locally by activation of the polysaccharide synthetase zymogen. Initially, caspase-9 is made as an inactive single-chain zymogen. Corin is synthesized as a zymogen that is activated by PCSK6. This type of inactive precursor to an enzyme is known as a zymogen or proenzyme. A zymogen (), also called a proenzyme (), is an inactive precursor of an enzyme. Trypsin is produced as the inactive zymogen trypsinogen in the pancreas. All MMPs are synthesized in the latent form (Zymogen). CPB2 is synthesized by the liver and circulates in the plasma as a plasminogen-bound zymogen. The protein of MMP7 is secreted as zymogen. In pancreatic acinar tissue, these subunits were found in zymogen granules.