Opals are composed of complicated crystalline aggregates of partially hydrated silicon dioxide. This results in protein aggregates, which then form dense plaque fibers. Platelets modulate neutrophils by forming platelet-leukocyte aggregates (PLAs). The heavy aggregates of mucin determine a cystic structure. Cherts are subject to problems when used as concrete aggregates. Initially, the proIAPP aggregates within secretory vesicles inside the cell. There are two main types of emulsions with different affinity for aggregates, cationic and anionic. It is sometimes mixed with lightweight aggregates, such as perlite or vermiculite. Without efficient autophagy, neurons gather ubiquitinated protein aggregates and degrade. This typically occurs in the area overlying lymphoid aggregates. Bacteria are largely responsible for the remineralisation and fragmentation of aggregates. The poly G tails form intermolecular tetrads that result in high molecular weight aggregates. Temporary tables can also be updatable for computation of complex aggregates. Larger numbers and sizes of such highly oxidized aggregates are associated with aging. Many neurodegenerative diseases show unusual protein aggregates.