The questionnaires were selected based on their use in psychobiological research. From 1949 to 1954, he was director of research at Creedmoor Institute for Psychobiological Studies. He insisted that patients could best be understood through consideration of their "psychobiological" life situations. Models based on psychobiological theories of personality have each incorporated a factor similar to agreeableness. Media naturalness theory is also known as the psychobiological model. Such examples illustrate the extent to which the psychobiological drive to belong is entrenched. State anger (S-Anger) is a psychobiological state or condition.