Chronic hepatitis C is a major cause of liver cirrhosis and hepatocellular carcinoma. Those who develop cirrhosis or liver cancer may require a liver transplant. Excessive consumption of alcohol can cause liver cirrhosis and alcoholism. NASH can then lead to complications such as cirrhosis and hepatocellular carcinoma. Glycerol metabolization is reduced in both cirrhosis and fatty liver disease. Ultrasound surveillance for hepatocellular carcinoma is recommended in those with accompanying cirrhosis. Prolonged use leads to cirrhosis and liver failure. Biopsies of patients given the treatment show reductions in liver damage and cirrhosis. More than 40% of people with cirrhosis develop hepatic encephalopathy. He also had progressive liver cirrhosis and existing ascites. Rates of liver cirrhosis, alcoholic psychosis, and infant mortality also declined. Hepatocellular carcinoma is a primary liver cancer that is more common in people with cirrhosis. People with ascites due to cirrhosis are at risk of spontaneous bacterial peritonitis. Specifically, it is effective as secondary prevention of hepatic encephalopathy in people with cirrhosis. This can lead to scarring (fibrosis) and cirrhosis.