Infection usually occurs as tinea capitis with suppuration and kerion formation. Prophylactic treatment consists in prevention of suppuration. There is no suppuration and sinus formation. These ulcers start with callosity under which suppuration takes place. There may or may not be associated with pus & suppuration. For non-resolving suppuration, surgical excision may be required. It is used medicinally to treat suppuration, common colds, and lithiasis. Hemorrhage, suppuration and necrosis are therefore the initial conditions leading to the xanthogranulomatous response. If suppuration occurs, it may need needle aspiration. The teeth often appeared sound and suppuration was not present. Often, these painful interventions resulted in suppuration of the eyes and blindness of the victims. It typically involves the bulbar conjunctivae, is not accompanied by suppuration, and is not painful. The insert song, "Suppuration -core-" (also sung by Kotoko), was used in episode five. Ischiorectal abscess is formed when suppuration transverses the external anal sphincter into the ischiorectal space. Chronic suppuration; vulvar abscesses have been reported in approximately 17% of the patients.