Migraine and migraine with aura are common comorbidities. Cluster headache may be misdiagnosed as migraine or sinusitis. Trial three enrolled patients with a history of chronic migraine headaches. It may occur as an isolated symptom without headache in acephalgic migraine. Valproate is also used to prevent migraine headaches. Neuroimaging is not indicated for patients with stable headaches which are diagnosed as migraine. It is also found in clinical depression, derealization, brain tumor, and migraine headaches. Verapamil is used for controlling ventricular rate in supraventricular tachycardia and migraine headache prevention. Sumatriptan is effective for ending or relieving the intensity of migraine and cluster headaches. Minute amounts have been reported to stop cluster and migraine headaches. Similar effects can sometimes occur during epilepsy or migraine auras. Spinal manipulation for treating an ongoing migraine headache is not supported by evidence. Some research has pointed to the link between astigmatism and higher prevalence of migraine headaches. Symptoms such as difficulty breathing, migraine, or stomach heat sensation may indicate an intolerance.