Being Human has provided funding to treat children with congenital heart defects and craniofacial deformities. It is characterized by advanced osseous maturation and distinctive craniofacial, skeletal and neurological abnormalities. Orthognathic surgery is often needed after reconstruction of cleft palate or other major craniofacial anomalies. Expansion of craniofacial lesions may lead to progressive facial deformity. Accurate evaluation of craniofacial malformations is usually possible with the ultrasound scan performed during pregnancy. Several characteristic craniofacial abnormalities are often visible in individuals with FAS. Some of these craniofacial syndromes are genetic, others are from unknown causes. People who have social phobia are particularly prone to idiopathic craniofacial erythema. Training in craniofacial surgery requires completion of a Craniofacial surgery fellowship. There are a few syndromes like the Freeman-Sheldon and Gordon syndrome, which have craniofacial involvement. SHH plays a very important role in organogenesis and most importantly craniofacial development. This complex operation marked the beginnings of the speciality of craniofacial surgery. There is no specific board for craniofacial surgery. A significant majority of craniofacial changes occur during adolescence. About 150 genes are associated with craniofacial conditions presenting with malocclusions.