Estrogens can be grouped as steroidal or nonsteroidal. Nonsteroidal antiandrogens have relatively low affinity for the AR compared to steroidal AR ligands. It is a nonsteroidal open-ring analogue of the steroidal estrogen estradiol. AR antagonists are classified into two types, based on chemical structure&colon; steroidal and nonsteroidal. C. They also contain bitter compound called flabelliferrins, which are steroidal saponins. It contains steroidal alkaloids such as cyclobuxine. The subset of saponins that are steroidal have been termed saraponins. The active ingredients are thought to be isosteroidal and steroidal alkaloid compounds. Cyclopamine (11-deoxojervine) is a naturally occurring chemical that belongs in the family of steroidal alkaloids. Withanolides are a group of naturally occurring C28- steroidal lactones. This is in contrast to steroidal antiandrogens like spironolactone and cyproterone acetate. These can include caffeine, stimulants, steroidal drugs and antiparkinsonian drugs. The Easter lily is a rich source of steroidal glycosides. Dr. Pincus began studying hormonal biology and steroidal hormones early in his career. Most antimineralocorticoids, including spironolactone, are steroidal spirolactones.