Several techniques exist for the creation of apomorphine from morphine. His condition improved when he began injections of apomorphine. Non-ergoline agonists are pramipexole, ropinirole, rotigotine, piribedil and apomorphine. It is structurally related to apomorphine. The patients were subjected to apomorphine injections and electric shocks. These include apomorphine, pergolide, rotigotine, and terguride. There are a number of stability concerns with apomorphine such as oxidation and racemization. Reduction of beta-amyloid levels is a common target of compounds (such as apomorphine) under investigation. An animal who undergoes severe respiratory depression due to apomorphine can be treated with naloxone. The priaprism is caused by apomorphine increasing arterial blood supply to the penis. A veterinarian may use an emetic such as apomorphine to cause the dog to vomit. When an episode sets in, the apomorphine is injected subcutaneously, and signs subside. Apomorphine was one of the earliest used pharmacotherapies for alcoholism. Apomorphine has a catechol structure similar to that of dopamine. Apomorphine may be used however its use is supported by little evidence.