It is a common cause of otherwise unexplained gastrointestinal bleeding and anemia. Maternal mortality caused by severe bleeding and infections are mostly after childbirth. It causes irritation, blistering, bleeding and discomfort. Symptoms other than bleeding are not common. Later, symptoms may include feeling tired, shortness of breath, easy bleeding, or frequent infections. Heavy menstrual bleeding, occurring monthly, can result in anemia. They are not associated with upper gastrointestinal bleeding and kidney toxicity. People with prior history of ulcer disease or GI bleeding require special precaution. This may be due to medications, dehydration, significant bleeding or infection. Hemosiderin often forms after bleeding (haemorrhage). Hematochezia can be due to upper gastrointestinal bleeding. This is important for patients who have systemic cause for bleeding. They are at risk of trauma with subsequent excessive bleeding, thrombosis or calcification (2). At the time, Merck was interested in developing substances that stopped abnormal bleeding. Victoria then notices that Sonne is bleeding profusely from his wound and calls an ambulance.