But the role of the counsellor differs from the role of the mediator. He also serves as an impartial adviser to the boss and mediator in internal disputes. A papal representative was present to act as mediator. The criteria for mediator competence is under dispute. Activated macrophages and monocytes secrete HMGB1 as a cytokine mediator of Inflammation. It is also referred to as a bioactive lipid mediator. This involves the identification of mediator and moderator variables. He proposed that Germany would act as a mediator. Jesus is the mediator of the New Covenant. Interleukin 1 is suspected to be a cytokine mediator that promotes hair loss. After this, he was especially known for acting as a mediator between conflicting parties. It has been shown to be a critical mediator of the colonic inflammatory response. Social-cognitive models of health behavior change cast self-efficacy as predictor, mediator, or moderator. Instead, the Facilitative mediator facilitates the conversation. Once subscribed by both parties and the Mediator, the agreement is official.