Natural selection for genomic imprinting requires genetic variation in a population. More common are mutations, which are changes in the nucleotide sequence of genomic DNA. Many of these changes are mutations, or changes in the nucleotide sequence of genomic DNA. Blast2GO is a bioinformatics platform for functional annotation and analysis of genomic datasets. In their publication, they reported a detailed analysis of the genomic and genetic data. Kozak discovered the sequence through a detailed analysis of DNA genomic sequences. The H locus contains four exons that span more than 8 kb of genomic DNA. Absence of cytosolic SOD causes a dramatic increase in mutagenesis and genomic instability. The mRNA sequence is determined by the sequence of genomic DNA. Capsid components enter the nucleus in order to encapsidate new viral genomic DNA. Much of the analysis of genomic data sets also include identifying correlations. "Functional annotation" consists of attaching biological information to genomic elements. The replisome is responsible for copying the entirety of genomic DNA in each proliferative cell. "Structural annotation" consists of the identification of genomic elements. This is especially useful in identifying sequences to either side of various genomic inserts.