Subthreshold panic disorder sufferers were found to significantly benefit from use of CBT. With this hopefully more pain management will be available including techniques for arthritis sufferers. Anxiety or excitement can exacerbate the condition for many sufferers. Helium is sometimes used to improve the ease of breathing of asthma sufferers. Not all ICP sufferers have all of the above symptoms. Benzoate was shown in a study to cause hypersensitivity in some asthma sufferers. Lickint showed that lung cancer sufferers were likely to be smokers. He says that he and his children are asthma sufferers. Olsen has also been an advocate for migraine sufferers since 1998. Physical therapy provides some relief for sufferers of neck, back, or shoulder pain. He notes that most of the sufferers became delirious before they succumbed to the disease. It can be extremely painful in some sufferers. In 1963 the area was seen as "famous for its climate beneficial to asthma sufferers". In pursuit of added relief sufferers can inadvertently cause tissue damage or death, i.e. necrosis. DNase enzymes can be inhaled using a nebuliser by cystic fibrosis sufferers.