Deletion/duplication analysis can be used to detect the 15% of mutations that are submicroscopic deletions. Viruses are submicroscopic parasites that replicate inside host cells. SHFM3 is unique in that it is caused by submicroscopic tandem chromosome duplications of FBXW4/DACTYLIN. Next, proteins undergo a nucleation phase, where submicroscopic sized protein aggregates, or particles, are generated. All the other classes are submicroscopic.