They are a 16-membered macrocyclic lactone derivatives with potent anthelmintic and insecticidal properties. Bithionol is an antibacterial, anthelmintic, and algaecide. They have several different effects like increasing appetite, tonic, diuretic, febrifugal, anthelmintic and anti-leukemic. There are several classes of anthelmintic drugs used to control gastrointestinal nematodes in livestock. Abamectin is a widely used insecticide and anthelmintic. It is described in the Pharmacopoeia of India as an astringent tonic, anthelmintic, and antiperiodic. In fact, large number of piperazine compounds have an anthelmintic action. Sap is used to treat scabies and anthelmintic (tapeworm). Given the importance of effective parasite control, there is heightened concern over reduced anthelmintic efficacy. It is also used as an anthelmintic (to expel parasitic worms). Gentian is a sialagogue, hepatic, cholagogue, anthelmintic, and emmenagogue. Also, fenbendazole itself is an active metabolite of another anthelmintic drug, febantel. Targeting these receptors has been the therapeutic goal of anthelmintic therapy using avermectins. Side effects of anthelmintic drug treatment may include nausea, abdominal pain, headaches or dizziness. It is active against worms (anthelmintic) and mites (miticide).