Many allergens such as dust or pollen are airborne particles. The inflammation is caused by viruses, bacteria, irritants or allergens. It results from either exposure to allergens (allergic contact dermatitis) or irritants (irritant contact dermatitis). Common allergens include pollen and certain foods. Some of these cross-react to allergens from house dust mites. IgE antibodies bind to antigens of allergens. Neuroimmune interactions also occur when pathogens, allergens, or toxins invade an organism. Asthma is associated with exposure to indoor allergens. Basidiospores are the dominant airborne fungal allergens. These allergens are also linked with asthma. It provides minimal protection against liquids and little or no protection from dust mite allergens. Other significant fungal allergens include aspergillus and alternaria-penicillin families. There is negative skin test to common inhalant allergens and normal serum concentrations of IgE. The eyes may water in response to dry air, dust, or airborne allergens. A very broad range of substances can be allergens to sensitive individuals.