Anti-infective agents include antibiotics, antibacterials, antifungals, antivirals and antiprotozoals. Treatment options include antifungal shampoo, systemic antifungals, or both. Specific medications used to treat infections include antibiotics, antivirals, antifungals, antiprotozoals, and antihelminthics. Systemic therapy with oral antifungals including itraconazole, fluconazole, ketoconazole, and terbinafine is effective. Azole antifungals, such as ketoconazole, may inhibit the metabolism of clonazepam. Imidazoles belong to the class of azole antifungals, which includes ketoconazole, miconazole, and clotrimazole. Ketoconazole was introduced as the prototypical medication of the imidazole group of antifungals. These cuticular cultures are both antibiotics and antifungals. Like many other antifungals and antibiotics, nystatin is of bacterial origin. Depending on the causal agents, antivirals or antifungals can be added. The dose for daclatasvir should be lowered when taking with antifungals, such as ketoconazole. Systemic antifungals are administered orally or intravenously. Examples of non-azole systemic antifungals include griseofulvin and terbinafine. Isoquinolines are used in the manufacture of dyes, paints, insecticides and antifungals. Of the clinically employed azole antifungals, only a handful are used systemically.