Other potential methods based on tissue-targeted heating include cauterization, electrosurgery, and harmonic scalpel. Treatment options include 5-fluorouracil, imiquimod, scalpel vermillionectomy, chemical peel, electrosurgery, and carbon dioxide laser vaporization. Concerns have also been raised regarding the toxicity of surgical smoke produced by electrosurgery. Both cryosurgery and electrosurgery are effective choices for small areas of actinic cheilitis. "Surgical diathermy" is usually better known as "electrosurgery". He is recognized as the founder of electrosurgery of the bladder.