Differences occur firstly on whether the act has any spiritual significance. Rain holds an important religious significance in many cultures. The cultural significance of sawfish varies significantly. There is also evidence of damage to the heart of unclear significance. Water has specific symbolic significance for Christians. There is also a difference between statistical significance and practical significance. Opinions differ as to the significance of the word . There were no findings of misconduct of any significance found. The Macedonian period also included events of momentous religious significance. Other countries selected a date with historical significance. It is a broadcast market with historical significance. There are different opinions on the significance of these principles. It defines this as matters of "national environmental significance". These sites were designated as being of national historic significance. Confidence intervals are closely related to statistical significance testing.