The Big Five are characterized as openness, conscientiousness, extraversion, agreeableness, and neuroticism. The introvertive anhedonia factor has been linked to high neuroticism and low extraversion. Phlegmatic people are low in neuroticism and low in extraversion. Absorption is unrelated to extraversion or neuroticism. Similarly, interactions between extraversion, neuroticism, and conscientiousness have demonstrated significant impacts on subjective-well being. Neuroticism and extraversion are the two most widely studied traits. Melancholic people are high in neuroticism and low in extraversion (or more introverted). Sanguine people are low in neuroticism (or more emotionally stable) and high in extraversion. Neuroticism, Openness to Experience, and Extroversion. In general, women tend to score higher on neuroticism and agreeableness. Negative affectivity is related strongly to the personality trait of neuroticism. ASMR intensity is correlated with the openness-to-experience and neuroticism traits. Risk factors for mental illness include a propensity for high neuroticism or "emotional instability". It also commonly occurs with personality traits such as neuroticism. In particular, one theory focuses on the personality trait neuroticism.