These divide and differentiate into spermatocytes, which undergo meiosis to form spermatids. The spermatocytes divide by meiosis to form spermatids. DAZ pushes ESCs in to germ cells with molecular features of being spermatids. Spermatidogenesis is the creation of spermatids from secondary spermatocytes. I, and eventually 4 spermatids after meiosis II. This protein is localized to the nucleus of late spermatids where histone hyperacetylation takes place. CREM acts as a transcription factor essential for the differentiation of spermatids into mature spermatozoa. Alternatively, they go on to differentiate into spermatocytes, spermatids and finally spermatozoa. Mouse stem cells were grown into cells resembling spermatids in 2016. Spermatidogenesis is the creation of spermatids from secondary spermatocytes during spermatogenesis. Then each spermatocyte gives rise to four spermatids through meiosis. The spermatocytes then undergo meiosis, reducing their chromosome number by half, which produces spermatids. Secondary spermatocytes produced earlier rapidly enter meiosis II and divide to produce haploid spermatids. The two secondary spermatocytes undergo the second meiotic division to form four haploid spermatids. The spermatogenous cells give rise to spermatids via mitotic cell division.