Granulopoiesis consists of 5 stages, in which the myeloblast is the first recognizable cell. This prevents proper differentiation of blood cells, leading to the formation of Myeloblast. The malignant cell in AML is the myeloblast. The first unipotent cell in granulopoiesis is a myeloblast. The first cell that starts to resemble a granulocyte is a myeloblast. In AML, Myeloblast do not mature but grow and multiply with regulation.