Heparin is the most widely used intravenous clinical anticoagulant worldwide. The INR is typically used to monitor patients on warfarin or related oral anticoagulant therapy. Beginning warfarin treatment requires an additional a non-oral anticoagulant, often injections of heparin. These medications can include antiplatelet drug, anticoagulant, and fibrinolytics. Hemoptysis may be exacerbated or even caused by overtreatment with anticoagulant drugs such as warfarin. Treatment with anticoagulant and antiplatelet medications in this group appear similar. This can be avoided by using an alternative anticoagulant like sodium citrate or heparin. Both are granulated cells that contain histamine and heparin, an anticoagulant. Clotting abnormalities, such as those caused by anticoagulant medications, should be reversed. Heparin is usually administered in this form as an anticoagulant. It is the target of anticoagulant warfarin. The blood is kept from clotting by an anticoagulant in the saliva. Warfarin is a derivative of dicoumarol, an anticoagulant originally discovered in spoiled sweet clover. Another type of anticoagulant is the direct thrombin inhibitor. Patients with no history of thrombosis and a lupus anticoagulant should probably be observed.