Inhibitors and inducers of cytochrome P450 enzymes may interact with various antiandrogens. Inhibitors and inducers of cytochrome P450 enzymes may interact with CEEs. Inhibitors and inducers of the cytochrome P450 enzyme CYP3A4 may interact with CPA. Conversely, CYP3A4 inducers decrease alectinib concentrations and increase M4 concentrations. No relevant interactions with enzyme inhibitors and inducers are expected. These highly reactive compounds are potent inducers of Phase II enzymes in vitro. The enzyme inducers phenobarbital and phenytoin have been found to lower its blood plasma concentrations. Following is a table of selected substrates, inducers and inhibitors of CYP3A4. Following is a table of selected substrates, inducers and inhibitors of CYP2D6. Patients should also not consume CYP3A inhibitors or inducers while taking palbociclib. Following is a table of selected substrates, inducers and inhibitors of CYP2B6. Following is a table of selected substrates, inducers and inhibitors of 2C8. Following is a table of selected substrates, inducers and inhibitors of CYP1A2. Following is a table of selected substrates, inducers and inhibitors of CYP2C9. The following is a table of selected substrates, inducers and inhibitors of CYP2C19.