Proximal diabetic neuropathy is most commonly seen people with type 2 diabetics. Brittle diabetes occurs no more frequently than in 1% to 2% of diabetics. Early studies in diabetics improved plasma glucose levels. It is common in diabetics who use conventional insulin injection treatment. Glucose testing strips designed for human diabetics are inexpensive and available at most pharmacies. The normal counter regulatory responses to hypoglycemia are impaired in type 1 diabetics. In 1949 purified insulin was shown to regenerate fat in diabetics with Lipoatrophy. This property makes them popular sweeteners among diabetics and people on low-carbohydrate diets. By the 1830s, Western doctors were recommending wheat gluten in diets for diabetics. BNP may be a reliable predictor of cardiovascular mortality in diabetics. The South has a higher percentage of obese people and diabetics. Vitamin D insufficiency is common in diabetics. Fructose is also used as a sweetener for use by diabetics. Peripheral artery disease affects one in three diabetics over the age of 50. It is more likely to occur in diabetics, alcoholics, or those who are immunocompromised.