Then they penetrate the mucosa and submucosa and enter venules or lymphatics. The meningeal lymphatics also carry immune cells. The enriched lymph originating in the lymphatics of the small intestine is called chyle. These channels are the lymphatic channels, or simply "lymphatics". Rupture of the lymphatics causes protein loss into the intestines. The ovary also contains blood vessels and lymphatics. The serosa contains blood vessels and lymphatics. It also transmits nerves and lymphatics. Mesenteries provide a pathway for vessels, nerves, and lymphatics to the organs. SSRs are found with high density in numerous malignancies, including CNS, breast, lung, and lymphatics. Thyroid cancer can spread directly, via lymphatics or blood. The most common cause of lymphangiectasia was congenital malformation of the lymphatics. Within days to weeks after initial infection, "Treponema pallidum" disseminates via blood and lymphatics. The general structure of lymphatics is based on that of blood vessels. However, little is known about a role of abnormal lymphatics and VEGF-D in LAM pathogenesis.