It is an example of dystrophic calcification. Research has discovered dystrophic (defective development) human microglia. Alopecia, dental anomalies, and dystrophic nails are observed. Mutations in this gene are associated with all forms of dystrophic epidermolysis bullosa. Dystrophic calcinosis cutis has also been reported. Osteodystrophy is any dystrophic growth of the bone. The mineralized portion may be bone, cementum-like, or dystrophic calcifications. Now accepted that majority of cases develop from dystrophic calcification of cyst contents. The main themes are the extreme weakness, slowness, gauntness, and emaciation of a dystrophic patient. The bacteria are found in high numbers and have great growth potentials despite dystrophic conditions. The most common type of calcinosis is dystrophic calcification. In LOAD brains, GAB2 is overexpressed in neurons, tangle-bearing neurons, and dystrophic neuritis. Experiments in alpha-sarcoglycan deficient dystrophic mice have shown that mesoangioblast transplantation can restore muscle function. Dystrophic lakes have a high level of dissolved organic carbon. In 1976, Friedrich defines LS as a dystrophic, not atrophic condition; "et atrophicus" dropped.