Cardiac muscle is slightly different from skeletal muscle. Striated muscle is further classified as either skeletal or cardiac muscle. Taurine is necessary for normal skeletal muscle functioning. The muscular system is an organ system consisting of skeletal, smooth and cardiac muscles. Cardiomyocytes show striations similar to those on skeletal muscle cells. They bind to calcium channels in cardiac and skeletal muscle, blocking nerve transmission. Satellite cells are crucial for skeletal muscle adaptation to exercise. High rates of carpal tunnel syndrome and other muscular and skeletal disorders are reported. High intensity exercise has been shown to result in reduced DNA methylation in skeletal muscle. It results in a generalised increase in skeletal muscle tone. Research on skeletal muscle properties uses many techniques. DTI also has applications in the characterization of skeletal and cardiac muscle. Loss of these neurons prevents the sending of signals between the brain and skeletal muscles. Patients tend to demonstrate a unique pattern of skeletal abnormalities. They are expressed in skeletal and cardiac myocytes.