Sinus infections are treated by prolonged courses of antibiotics. Doxycycline, like other tetracycline antibiotics, is bacteriostatic. Tuberculous meningitis requires prolonged treatment with antibiotics. Treatment is by removing the pus, antibiotics, sufficient fluids, and pain medication. Carbapenems are contraindicated in patients with prior allergic reactions to beta lactam antibiotics. For some infections it is used in addition to other antibiotics. It consists of treatment with intravenous antibiotics and fluids. Some organisms produce peptides as antibiotics, such as microcins. Certain antibiotics (such as rifaximin) and probiotics are other potential options. In the case of an immunocompromised patient antibiotics should be prescribed. Many antibiotics, particularly the macrolide antibiotics, are ionophores. The disease is treatable with antibiotics, which prevent most complications. However, there are certain general causes for concern with topical administration of antibiotics. It is one of the most commonly prescribed antibiotics in children. Steroids may speed recovery in those on antibiotics.