Inhibited protein synthesis impairs both virus replication and infected host cells. The impairment of either gene for the protein dimer impairs the protein function. There is also evidence that anxiety impairs both the inhibition and the shifting function. Second, anxiety impairs the inhibition function, and third, anxiety impairs the shifting function. Conversely, precluding or reverting endogenous electric current and fields impairs regeneration. The ingestion of oil causes dehydration and impairs the digestive process. Defective collagen fibrillogenesis impairs wound healing. Alcohol abuse can result in brain damage which impairs working memory. Furthermore,suppression of E-cadherin impairs intracellular adhesion. Chlordiazepoxide in laboratory mice studies impairs latent learning. Sin impairs free will, while grace restores it. There is evidence that damage to the lateral pallium impairs spatial memory. Sleep loss seen in shift workers greatly impairs cognitive performance, being awake for 24 hrs. Failure of this enzyme ultimately impairs the operation of ATPases. In effect, ARDS impairs the lungs' ability to exchange oxygen and carbon dioxide.