Oftentimes with reduplication and triplication produce consonant clusters. The gene mutation is an 85-kb tandem triplication, occurring naturally. These stations recently underwent extensive renovations, including line triplication. Other variations such as duplication, triplication, absence, and fenestration are much less common. A triplication of the little finger is very rare. Further triplication north of Beenleigh has also been proposed. The Pingelapese language uses reduplication and triplication. Down syndrome (DS) is caused by a triplication of chromosome 21. ABC1 exporters evolved by intragenic triplication of a 2 TMS precursor (TMS = transmembrane segment. Few languages employ triplication in their language. Reduplication and triplication are not to be confused with tense however. Triplication shows that the action is "still" happening. Triplication is the term for this phenomenon of copying two times.