It is less sedating than older antihistamines. Recreational users of carisoprodol usually seek its potentially heavy sedating, relaxant, and anxiolytic effects. Consequently, unlike the H-antihistamines which are sedating, H-antihistamines have stimulant and cognition-modulating effects. Noscapine can increase the effects of centrally sedating substances such as alcohol and hypnotics. Like most other antipsychotics, ziprasidone is sedating due primarily to serotonin and dopamine blockade. Like all first generation antihistamines, it is sedating. The most common side-effects of benzodiazepines are related to their sedating and muscle-relaxing action. Cetirizine, although less sedating, is non-dialyzable and possesses similar anti-histaminergic properties. It is more effective than metoclopramide, and less sedating than cyclizine or droperidol. Olanzapine, another sedating second-generation antipsychotic, has also been abused for similar reasons. Instead of sedating some patients, midazolam can make them violent. Dry mouth and sedating effects are due to alpha-2 agonism. It tends to be slightly activating/stimulating rather than sedating, unlike most others TCAs. The effects of other sedating drugs and alcohol, as well as antihypertensives, can be increased. It may also be used for sedating people who are agitated or anxious.