Side effects include decreased libido and ejaculatory or erectile dysfunction. Isotretinoin is also associated with sexual side effects, namely erectile dysfunction and reduced libido. The lack of sexual desire in men is because of loss of libido, low testosterone. With the increased levels of testosterone, sexual activity, libido and overall wellbeing should improve. Testosterone is one of the hormones controlling libido in human beings. Decreased libido and erection problems are a common side effect. They may not recognize a gradual loss of sexual function or libido. Less common adverse effects include vomiting, anxiety, hypertonia, cystitis, and increased libido. Androgen levels have been implicated in the regulation of human aggression and libido. Other users try enrolling in psychotherapy to solve depression-related issues of libido. Medication for libido reduction could be used if deemed necessary. This combination increases libido and performance simultaneously. Estrogens are involved in libido (sex drive) in both women and men. These are typically instinctual, such as hunger, thirst, and the drive for sex, or libido. Karen begins developing superpowers and an increased libido.