Her childlessness would be the greatest source of unhappiness in her life. Increased taxes on childlessness and on unmarried persons were enforced. Being unmarried is one of the strongest predictors of childlessness. He and his wife Anne were deeply grieved by their childlessness. Medical interventions may be available to some individuals or couples to treat involuntary childlessness. The Great Depression also impoverished these generations, for whom voluntary childlessness was almost absent. The family fell into the grief of childlessness. The first three categories are often grouped under the label "involuntary childlessness". To punish this crime Amyntor called upon the Erinyes to curse Phoenix with childlessness. Amyntor, discovering this, called upon the Erinyes to curse him with childlessness. Among the elderly, childlessness can be a cause for social isolation. Social causes of childlessness have now completely disappeared for women in union. Raj drinks and becomes depressed over his childlessness. By 1859, after seventeen years of childlessness, Ernest took no further interest in his wife. The film opens with two couples visiting their GP for childlessness.