Benzodiazepines should generally be avoided during the first trimester of pregnancy. The laboratory specializes in prenatal screening during the first trimester of pregnancy. Use is not recommended during breastfeeding or the third trimester of pregnancy. This tends to occur in the third trimester of pregnancy. Efavirenz is safe to use during the first trimester of pregnancy. Infection during the third trimester can cause a miscarriage. She is in the final trimester of her pregnancy. Surgery is generally safe, but pelvic surgeries during the first trimester may cause miscarriage. In pregnancy, ALT levels would rise during the second trimester. It should be considered after first trimester miscarriage. Use is not recommended in the third trimester of pregnancy. Grace was revealed to be in her first trimester of pregnancy. It is also effective in the second trimester of pregnancy. Specifically, the pregnancy goes well until about midway through the second trimester, where complications arise. Accuracy has been reported at 98.6% in the first trimester of pregnancy.