Corvalol may increase CNS depressant effect of other sedatives and hypnotics. Sedatives, analgesics and paralytic agents are often used. Other medications suggested include sedatives, anti-depressants, and anti-epileptic drugs. Short-acting and intermediate-acting barbiturates are usually prescribed as sedatives and sleeping pills. She often took barbiturates, laudanum, and other sedatives for her condition. These results suggested a relationship between abuse of sedatives or hypnotics and cerebral disorder. Dexmedetomidine may enhance the effects of other sedatives and anesthetics when co-administered. Night-time scratching can be reduced with sedatives and antihistamines. Physical withdrawal from some sedatives can be potentially lethal, for instance benzodiazepine withdrawal syndrome. Concomitant use of alcohol and other sedatives may potentiate this effect. Many people with insomnia use sleeping tablets and other sedatives. Sedatives and alcohol are sometimes combined recreationally or carelessly. Milly then attempts to kill Henrietta with an overdose of sedatives. Alcohol or other sedatives can make this worse. Dutroux later went on to use those sedatives to sedate his victims.