It is a preparation of purified bovine testicular hyaluronidase. It is a preparation of purified ovine testicular hyaluronidase. It is a preparation of purified bovine testicular hyaluronidase, a protein enzyme. Other examples include lactase, amylase, chitinase, sucrase, maltase, neuraminidase, invertase, hyaluronidase and lysozyme. The role of hyaluronidase in the disease process is controversial. In Eutherian mammals the acrosome contains digestive enzymes (including hyaluronidase and acrosin). Within infected tissues, this yeast produces several enzymes such as proteinase, phospholipase, hyaluronidase and chondroitin-sulphatase. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. A PEGylated drug candidate based on Halozyme's proprietary rHuPH20 enzyme (a recombinant human hyaluronidase enzyme). Halozyme has one FDA approved product (Hylenex recombinant, hyaluronidase human injection). Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency. In 1966, Cameron published his first book, "Hyaluronidase and Cancer". Almost all snake venom contains "hyaluronidase", an enzyme that ensures rapid diffusion of the venom. Halozyme's business is primarily focused on its proprietary and patented recombinant human hyaluronidase enzyme, rHuPH20. An investigation published in 2017, attributed an additional function to the Hyaluronidase 2 (HYAL2) protein.