Medical devices such as asthma nebulizers and inhalers were also reported as means of application. Predisposing factors include use of corticosteroid sprays or inhalers or immunosuppression. Recent evidence shows that nebulizers are no more effective than metered-dose inhalers (MDIs) with spacers. These come as nasal sprays, inhalers, and as oral pills. In 2008 all CFC inhalers were phased out and hydrofluoroalkane (HFA) inhalers replaced them. More specifically, some people with asthma reported higher use of quick-relief medications (inhalers). Topical (gels, creams or inhalers) or systemic steroids may be used to reduce inflammation. E-cigarettes provide nicotine to the blood quicker than nicotine inhalers. It is used as propellant for some metered dose inhalers. The yield of nicotine users obtain is similar to that of nicotine inhalers. Meanwhile, Peyton, who knows that Claire suffers from asthma, empties all of her inhalers. On December 31, 2008, the use of CFCs for medical inhalers were banned. Many of these early inhalers needed heat to vapourize the active chemical ingredient. This was much more convenient for patients than the previously used squeeze-bulb inhalers. Clenil, Qvar are brandnames for the inhalers.