Additional ingredients in avocado sauce can include tomatillo, onion, chili peppers, cilantro and garlic. It is based on tomatillo and green chili peppers. The second most popular dish was the "Green Sauce," an avocado and tomatillo sauce. Cooking or roasting the tomatillo will enhance the flavor, providing a sweeter salsa. The tomatillo fruit is surrounded by an inedible, paper-like husk formed from the calyx. The tomatillo is a member of the genus "Physalis", erected by Carl Linnaeus in 1753. Ixocarpalactone A, isolated from the tomatillo ("Physalis philadelphica"), shows promise as an anti-tumor agent. Thus, isolated tomatillo plants rarely set fruit. Tomatillo is mainly cultivated on outdoor fields in Mexico and Guatemala on a large scale. Tomatillo plants are highly self-incompatible, and two or more plants are needed for proper pollination. Transplanting is the most common practice to plant tomatillo plants. Tomatillo plants prefer full sun exposure and warm locations. The tomatillo can be harvested at different stages of its development. In general tomatillo plants are tolerant to many different soil conditions. Tomatillo plants can reach heights of 1.5 to 2 meters.