He made contributions to the field of human mycoses. Organisms that cause systemic mycoses are inherently virulent. It has the highest prevalence of all systemic mycoses (fungal infections) in the area. Ciclopirox is a synthetic antifungal agent for topical dermatologic treatment of superficial mycoses. Tinea, or ringworm, is any of a variety of skin mycoses. It is used for the topical treatment of superficial mycoses of the skin. It is useful as an antifungal antibiotic drug for topical as well as systemic mycoses. Examples of opportunistic mycoses include Candidiasis, Cryptococcosis and Aspergillosis. In general, primary pathogens that cause systemic mycoses are dimorphic. Oral ketoconazole has been replaced with oral itraconazole for many mycoses. Topical and systemic antifungal drugs are used to treat mycoses. Subcutaneous mycoses involve the dermis, subcutaneous tissues, muscle and fascia. At that time the title was changed to "Mycoses". Most strains of "P. verrucosa" available in culture collections are derived from human mycoses. Superficial mycoses are limited to the outermost layers of the skin and hair.