This can be explained by taking into account fibril breakage. Data suggest tenascin is a regulator of collagen fibril spacing. A decrease in Young's modulus of the transverse fibril was observed. Prior to binding to an amyloid fibril, ThT emits weakly around 427 nm. A microfibril is a very fine fibril, or fiber-like strand, consisting of glycoproteins and cellulose. TTR tetramer dissociation is known to be rate-limiting for amyloid fibril formation. Light entering the cornea is scattered by each fibril. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Fibronectin in the Reinke's space appeared to guide those fibers and orient the fibril deposition. "In vitro" studies have shown that CSPGs promote beta amyloid fibril formation. Fibril bundles are organized to form fibres with the elongated tenocytes closely packed between them.