The catecholamine activation is more strongly norepinephrine than epinephrine. Phosphorylation at Ser40 relieves feedback inhibition by the catecholamines dopamine, epinephrine, and norepinephrine. Uncoupling proteins are increased by thyroid hormone, norepinephrine, epinephrine, and leptin. Dopamine itself is used as precursor in the synthesis of the neurotransmitters norepinephrine and epinephrine. Antiadrenergic agents inhibit the signals of epinephrine and norepinephrine. It also impacts the beta adrenergic response similar to epinephrine and norepinephrine. Tyrosine is necessary for the production of neurotransmitters like epinephrine, norepinephrine, and dopamine. High levels of the hormones epinephrine, norepinephrine, and thyroid hormones can increase the heart rate. This is caused by the release of epinephrine and norepinephrine from the adrenal glands. MAO-B. MAO-A preferentially deaminates serotonin, melatonin, epinephrine, and norepinephrine. The sympathetic influence on heart rate is mediated by release of epinephrine and norepinephrine. Principle among these are glucagon, epinephrine, and growth hormone. CRH acts synergistically with arginine vasopressin, angiotensin II, and epinephrine. Examples are dopamine, serotonin and epinephrine. Treatment options include diphenhydramine and/or an injection of epinephrine.