It is a constituent of some types of kidney stone. Zhao also pushed for increased research into the number of kidney stone babies. Cranberry juice components are also being studied for possible effects on kidney stone formation. The evidence for benefit with a kidney stone is better when the stone is larger. Calcium from bone may also play a role in kidney stone formation. In 2008 Mandelson was hospitalised, suffering from a kidney stone. In 1794 a treatise mentioned S.Pellegrino water as a treatment method for kidney stone disease. It is also found in urine, where it inhibits kidney stone formation. He died in 1612 in Venice, of complications from a kidney stone. Cromwell is thought to have suffered from malaria and from "stone" (kidney stone disease). In November 2006, LabCorp acquired "Litholink Corporation", a kidney stone analysis laboratory. Cases of recurrent kidney stone formation may warrant evaluation for possible underlying metabolic abnormalities. Carter missed seven games early in the season with a kidney stone. In June 1964, she underwent surgery to remove a kidney stone. The long term consumption of oxalic acid leads to kidney stone formation in humans.