Lymphatic drainage depends on the position of lymphatic vessels in the ureter. Lymph is present throughout the body, and circulates through lymphatic vessels. Lymph nodes are located at intervals along the lymphatic system. Proponents claim improvement in circulatory system and lymphatic drainage. Lymphedema is the swelling of tissues due to insufficient fluid drainage by the lymphatic vessels. Lymphoma refers to cancer that arises from lymphatic tissue. Among the most common are cancers affecting the adrenal glands, pancreas, and lymphatic system. The spleen is part of the lymphatic system. Inflammation of the lymphatic vessels is known as lymphangitis. The inner lining of the heart, lymphatic and blood vessels, develop from endothelium. This is achieved by the coronary circulation, which includes arteries, veins, and lymphatic vessels. Lymphangitis (inflammation of lymphatic vessels) is sometimes considered a type of vasculitis. Lymphangiomatosis is a disease involving multiple cysts or lesions formed from lymphatic vessels. The lamina propria is rich in blood vessels and lymphatic channels. The antibiotic doxycycline is also effective in treating lymphatic filariasis.