Garcia believed metformin to have bacteriostatic, antiviral, antimalarial, antipyretic and analgesic actions. Varieties of Coricidin may also contain acetaminophen (an analgesic/antipyretic) and guaifenesin (an expectorant). As an NSAID, indometacin is an analgesic, anti-inflammatory, and antipyretic. It also has analgesic, antipyretic, and platelet-inhibitory actions. Propyphenazone is a derivative of phenazone with similar analgesic and antipyretic effects. Ampyrone is a metabolite of aminopyrine with analgesic, anti-inflammatory, and antipyretic properties. It is used for its properties as an anti-inflammatory, antipyretic and analgesic drug. Ketoprofen is a common NSAID, antipyretic, and analgesic used in horses and other equines. It is variously regarded as an antipyretic, antispasmodic, antiparalytic, restorative and aphrodisiac. It is used in medicine as an analgesic and antipyretic. Phenazone was used before 1911 as an analgesic and antipyretic. Its analgesic and antipyretic effects begin to occur one to two hours following administration. It is also found in castoreum, which was used as an analgesic, anti-inflammatory, and antipyretic. It is besides used as a stimulant, diuretic, antioxidant, antipyretic and relieves spasmodic asthma. Ibuprofen has been shown more effective as an antipyretic than paracetamol (acetaminophen).