It is thus a combination of metrorrhagia and menorrhagia. It may represent a possible endocrine dysfunction, resulting in menorrhagia or metrorrhagia. These irregularities include metrorrhagia (intermenstrual bleeding), amenorrhea (absence of menstruation), and breakthrough bleeding. Metrorrhagia is from metro = measure, -rrhagia = abnormal flow. Metrorrhagia is bleeding at irregular times, especially outside the expected intervals of the menstrual cycle.