In animal models, pharmacological inhibition of ischemic succinate accumulation ameliorated ischemia-reperfusion injury. When gene flow occurs via migration the deleterious effects of inbreeding can be ameliorated. Administration of methionine ameliorated the pathological consequences of methionine deprivation. FAP can be ameliorated by liver transplantation. Micronutrients B, Mo are partly sufficient and can be easily ameliorated by increasing sludge release. However, the idea that mental illness could be ameliorated through institutionalization ran into difficulties. However, the idea that mental illness could be ameliorated through institutionalization was soon disappointed. Gold toxicity can be ameliorated with chelation therapy with an agent such as dimercaprol. This can be partially ameliorated via broad particle size distributions via the Farris effect. Caen has an oceanic climate that is somewhat ameliorated due to its slightly inland position. There have been successful therapies in single cases that have ameliorated the hallucinations. Their sufferings can be ameliorated with compassion and conscientious care. This issue is somewhat ameliorated with the improved scoring algorithm. Most of its significant effects in practice have been ameliorated by legislation. Smaller farms and more egalitarian conditions ameliorated unrest over the 19th and 20th centuries.