Carbon monoxide also binds to other molecules such as myoglobin and mitochondrial cytochrome oxidase. Celecoxib is predominantly metabolized by cytochrome P450 2C9. Inhibitors and inducers of cytochrome P450 enzymes may interact with various antiandrogens. Inhibitors and inducers of the cytochrome P450 enzyme CYP3A4 may interact with CPA. Inheriting abnormal alleles of cytochrome P450 can alter drug metabolism. Some complexes emulate the action of various heme enzymes such as cytochrome P450, lignin peroxidase. CYP3A4 is a member of the cytochrome P450 superfamily of enzymes. The TCAs are highly metabolised by the cytochrome P450 (CYP) hepatic enzymes. It binds with iron in the mitochondrial cytochrome enzymes, thus preventing cellular respiration. Most steroidogenic reactions are catalysed by enzymes of the cytochrome P450 family. Arene oxides are intermediates in the oxidation of arenes by cytochrome P450. It is an inhibitor of cytochrome P450 1A2. The dense cluster of neurons that comprise the oSDN express cytochrome P450 aromatase. Amiodarone inhibits the action of the cytochrome P450 isozyme family. Cilostazol is metabolized by CYP3A4 and CYP2C19, two isoenzymes of the cytochrome P450 system.