Hypersensitivity reactions include skin rashes, urticaria, fever, and anaphylaxis. Fever, macular and vesicular rashes, angioedema, urticaria, and anaphylaxis may occur. Desloratadine is used to treat allergic rhinitis, nasal congestion and chronic idiopathic urticaria (hives). Allergic reactions range from urticaria to anaphylaxis. Rarely, interstitial nephritis, urticaria, and angioedema have been reported with cimetidine treatment. The severity of symptoms vary, with dermatitis, pruritus and papular urticaria being common. Hypersensitivity reactions like skin rashes, urticaria and Stevens-Johnson syndrome have been reported. Hypersensitivity (including skin rash, urticaria, and fever) is sometimes reported when using transdermal methylphenidate. Sweating can trigger intense itching or cholinergic urticaria. Rarer side effects included panic attacks, impaired learning, tremor, jaundice, urticaria (hives), and myalgia. Urticaria (hives) may develop simultaneously. Sulfasalazine has been studied in cirrhosis, psoriasis, idiopathic urticaria, and amyloidosis. Numerous bites may lead to an erythematous rash or urticaria. Other more common symptoms include nausea, urticaria, and atopy. Horses with dourine show signs of ventral and genital edema and urticaria.