This acid immediately dissociates into hydrogen and bicarbonate ions. The acid dissociates in the aqueous environment producing hydronium ions, HO. The salt also dissociates into its constituent anions and cations. In solution it dissociates into glutamate and sodium ions. For example, sodium acetate dissociates in water into sodium and acetate ions. Thus PER/TIM dimer dissociates, and the unbound PER becomes unstable. Sometimes the solute dissociates or associates in the solvent. This trimeric G protein dissociates to G alpha and G beta/gamma subunits. When tau becomes hyperphosphorylated, the protein dissociates from the microtubules in axons. Once phosphorylated, pRB dissociates from the transcription factor E2F1. Arrhenius' explanation was that in forming a solution, the salt dissociates into Faraday's ions. In water, it dissociates into Na and Cl ions. Mandelonitrile, however, dissociates to benzaldehyde and hydrogen cyanide, and cannot be stabilized by glycosylation. Following complete assembly of the MHC molecule, calnexin dissociates. Water vapor dissociates into hydrogen and oxygen at the hot filament.