Studies showed no evidence of teratogenic or mutagenic effects. This may put these organisms at risk of mutagenic, teratogenic, and/or carcinogenic effects. Chronic animal studies show no evidence of carcinogenic or teratogenic effects. Dioctyl sodium sulfosuccinate is not known to be carcinogenic, mutagenic, or teratogenic. Triacetylethylenediamine is not mutagenic and not teratogenic. Salmon calcitonin is devoid of embryotoxic, teratogenic, and mutagenic potential. Ethyl methanesulfonate (EMS) is a mutagenic, teratogenic, and possibly carcinogenic organic compound with formula CHSO. Benzodiazepines have been found to cause teratogenic malformations. No data on human carcinogenic, teratogenic, or developmental effects have been created. Temozolomide is genotoxic, teratogenic and fetotoxic and should not be used during pregnancy. Several thousand newborns in Europe and elsewhere suffered the teratogenic effects of thalidomide. Methotrexate and leflunomide are teratogenic (harmful to foetus) and not used in pregnancy. Hexachlorobenzene may cause embryolethality and teratogenic effects. Studies in pregnant animals have shown teratogenic effects. Probably, the most well-known teratogenic drug is thalidomide.