When GSK-3 is phosphorylated, it is deactivated, and prevented from deactivating glycogen synthase. For example, phosphorylation is primarily involved in activating and deactivating proteins and in signaling pathways. ARF-GAP1 is responsible for deactivating the ARF1 protein by activating the GTPase. Also, shoplifters deactivating or detaching tags may be spotted by the shop staff. GSK-3 is responsible for phosphorylating (and thus deactivating) glycogen synthase. Its chelating properties are useful in deactivating calcium and magnesium ions in hair products. It was also equipped with a deactivating liquid tank and underbelly spraying apparatus. Upon the deactivating signal, the protein becomes dephosphorylated again and stops working. This reaction is also possible with deactivating substituents on the aromatic group. The killer electrocutes McKenzie, deactivating the building's power and heating system. Octopussy realises that she has been tricked, and assists Bond in deactivating the warhead. It has pioneered an environmentally safe method of deactivating and recycling nuclear-powered ships. After deactivating the time dilation field, Minoko is kidnapped. The therapist follows the attachment model by addressing deactivating and hyperactivating strategies. Although NO affects many metalloproteins, it does so by deactivating them.