It is popularly referred to as a "superbug", more appropriately as multiple resistant Staphylococcus aureus. After her mastectomy, she contracted the superbug MRSA and had to be treated with Zyvox. Notably, the anticancer drug OSU-03012 re-sensitized superbug strains of Neisseria gonorrhoeae to several standard-of-care antibiotics. The film suggests we are sleepwalking into a superbug pandemic. Experts fear CRE as the new "superbug". The model for Superbug was "Herbie" from the Disney movie franchise that started in 1968. The Superbug series was relatively low-budget. Smith appeared as "Superbug" in the 1970 movie "MASH". The technological aspects of Superbug increase as the film series progresses. Superbug is portrayed as having countless gadgets and skills.