In vivo testing of mice that developed murine colon carcinoma tumour cells. Chimeric antibodies are composed of murine variable regions fused onto human constant regions. CA-125 was initially detected using the murine monoclonal antibody designated OC125. The genomes of exogenous and endogenous murine leukemia viruses have been fully sequenced. Loss of CD47 promotes proliferation and increases asymmetric division of primary murine endothelial cells. Antibodies may also referred to as murine, chimeric, humanized or human. This gene was discovered using a non virulent protein of murine leukemia virus. In addition, the haptoglobin gene is expressed in murine and human adipose tissue. This protein will block replication of some murine leukemia virus strains following reverse transcription. Gelsolin decreases actin toxicity and inflammation in murine multiple sclerosis. Radioimmunotherapy (RIT) involves the use of radioactively-conjugated murine antibodies against cellular antigens. Blinatumomab, a CD19-CD3 bi-specific monoclonal murine antibody, currently shows promise as a novel pharmacotherapy. Bacterial diseases carried by fleas include murine or endemic typhus and bubonic plague. In normal human, murine, and rat cells galectin-3 levels are low. There exists a 98% homology between human and murine homologues.