These misfolded AR proteins form aggregates in the cell cytoplasm and nucleus. Arrestins shuttle between cell nucleus and cytoplasm. Excess lipid accumulates in vesicles that displace the cytoplasm. The actin protein is found in both the cytoplasm and the cell nucleus. Autolysis is initiated by the cells' lysosomes releasing digestive enzymes into the cytoplasm. Each cell contains a dense cytoplasm and a prominent nucleus. Each typically has a cell membrane formed of phospholipids, cytoplasm and a nucleus. It assists in transferring fatty acids from the cytoplasm to mitochondria. It localizes to both the cytoplasm and the nucleus. Androgen receptors interact with certain signal transduction proteins in the cytoplasm. Granulocytes are leukocytes that have granules in their cytoplasm. Clathrin performs critical roles in shaping rounded vesicles in the cytoplasm for intracellular trafficking. For instance, lysosomes contain digestive enzymes that break down most biomolecules in the cytoplasm. These enzymes are present in the cytoplasm of the epithelial cells. Primed vesicles fuse very quickly in response to calcium elevations in the cytoplasm.