This causes an inflammatory response in the sheep resulting in severe irritation and pyrexia. TRPA1, TRPA- or TRPA1-like, TRPA5, painless, pyrexia, waterwitch, and HsTRPA. Common adverse effects included mild to moderate headache, pyrexia, chills, and fatique. Less common symptoms include pyrexia, anorexia, and joint pain caused by sterile suppurative arthritis. Animals may show systemic signs such as anorexia, lethargy and pyrexia (fever). There is usually an associated trismus, cervical lymphadenopathy, malaise and pyrexia. Pyrexia (fever) is one of the symptoms of contamination. In cattle, the disease causes diarrhoea and systemic signs such as pyrexia, lethargy and anorexia. Following his return to France, Birks was hospitalised for five days with pyrexia. Less specific signs include poor coat quality, pyrexia, cardiovascular, gastrointestinal, neurological and respiratory signs. On admission she had pyrexia, vomiting, heart murmurs, and albumen in the urine. Newland was admitted to the 38th Casualty Clearing Station with pyrexia on 4 December. Initial signs of the onset of PSS are pyrexia, panting, sweating, tachycardia and arrhythmias.