Renal papillary necrosis is a form of nephropathy involving the necrosis of the renal papilla. Renal function is an indication of the kidney's condition and its role in renal physiology. Risperidone undergoes hepatic metabolism and renal excretion. Trifluoperazine should be used with caution in patients suffering from renal or hepatic impairment. Treatment involves supportive therapy including renal dialysis. Uremia is commonly seen in patients who undergo dialysis due to renal insufficiency. It is subject to renal and pulmonary excretion. Interleukin-2 is used in the treatment of malignant melanoma and renal cell carcinoma. Docetaxel exhibits cytotoxic activity on breast, colorectal, lung, ovarian, gastric, renal and prostate cancer cells. Hemolysis, renal, and liver failure result. Paramesonephric malformations are usually related to abnormalities of the renal and axial skeletal system. No dose adjustment is needed for patients with renal impairment. Bruits can be present in case of renal or visceral arterial stenosis. It is the matrix of urinary casts derived from the secretion of renal tubular cells. These sentinel SNP are located within genes related to vascular smooth muscle and renal function.