Bone marrow studies including aspiration, flow cytometry, cytogenetics, fluorescent in situ hybridisation and molecular studies. These methods are mostly used in hematology, cytogenetics and stem cell research laboratories. This overlap includes immunoassays, flow cytometry, microbiology and cytogenetics and any assay done on tissue. Services offered include anatomical pathology, biochemistry, haematology, cytogenetics and microbiology. Cytogenetics and immunohistochemistry are other types of tissue tests. It is detected on cytogenetics or a karyotype of affected cells. A karyotype is a very useful tool in cytogenetics. Identification of the Philadelphia chromosome by cytogenetics is diagnostic for CML. The preparation and study of karyotypes is part of cytogenetics. Other methods are also commonly used, including cytogenetics and fluorescence in situ hybridization (FISH). Several chromosome-banding techniques are used in cytogenetics laboratories. Sequencing efforts provided a variety of products useful in molecular cytogenetics. In the 1980s, advances were made in molecular cytogenetics. Their work provided crucial information on Drosophila cytogenetics. These features have made the species a useful tool in laboratory investigations of Basidiomycete cytogenetics.