Clinically and pathologically, leukemia is subdivided into a variety of large groups. Vivien is despising, devious and habitually unfaithful while Lee is pathologically jealous. I based on the observed abnormal collagen fibrillogenesis resulting in pathologically thicker fibres. Irene Trent is unhappily married to a blind, pathologically possessive millionaire inventor, Howard. People with dissociative disorders use dissociation as a defense mechanism, pathologically and involuntarily. Endogenous substances typically have some physiological utility, but they can also be pathologically endogenous. Chromatolytic cells have also been observed in a pathologically similar disease known as Pick's disease. Although they are both hardened assassins, Wint is pathologically afraid of travelling. Basically, pathologically ambitious and actually lacking in any real humanity. However, it can also be pathologically altered in, e.g., carbon monoxide poisoning. More serious side effects may include suicide, mania, irregular heart rate, and pathologically prolonged erections. Such cases have a pathologically lowered threshold for the sound-evoked VEMP. Both stated that Peach had a thin skull, but not, as Mant observed, "pathologically thin". Women with pathologically low flow are more likely to have torsion. The Catholic League called Hill "pathologically miserable" and claimed her career was "in decline".