Hormone therapy for treatment of menopausal symptoms can also cause abnormal bleeding. Levonorgestrel is used in combination with an estrogen in menopausal hormone therapy. HRT is often given as a short-term relief from menopausal symptoms during perimenopause. Progestogens are used in combination with estrogens in menopausal hormone therapy in women. Prasterone is sometimes used as an androgen in menopausal hormone therapy. EE is also used as menopausal hormone therapy. HRT may be reasonable for the treatment of menopausal symptoms, such as hot flashes. Progestogens may increase the risk of cardiovascular disease in menopausal women. EC508 is currently under active development for use in menopausal hormone therapy. It is also used in the treatment of menopausal symptoms in women. American women of different ethnicities report significantly different types of menopausal effects. Menopausal flushing may also respond to moclobemide. Food sharing is also prevalent among another menopausal species, killer whales.