Tonic water is often used as a drink mixer for cocktails, especially gin and tonic. Pure powdered sulfur was used as a medicinal tonic and laxative. This makes the wine more tonic and astringent. A tonic cocktail is a cocktail that contains tonic syrup or tonic water. Rapid eye movement sleep can be subclassified into tonic and phasic modes. Leo was a drinker of the cocaine-infused wine tonic Vin Mariani. It is a bitter tonic and aromatic. Orange flower water is an example of a skin tonic. It may be spasmodic (clonic) or permanent (tonic). Green ume extract is used as a tonic in Japan. These subunits fire spontaneously in either a tonic or a phasic fashion. The quinine in tonic water will fluoresce under ultraviolet light. It is most commonly consumed mixed with tonic water. He prescribes 3 bottles of a tonic wine. It may also be drunk on ice or with tonic water.