Antibodies exert additive or synergistic effects with mechanisms of innate immunity. Antibodies are major components of humoral immunity. Infection with Japanese encephalitis confers lifelong immunity. STING plays an important role in innate immunity. This genetic system provides bacteria with acquired immunity to infection. This may complicate the process of using experimental animals as models of human innate immunity. Inoculation is a set of methods of artificially inducing immunity against various infectious diseases. Research into development of vaccines that will lead to immunity is ongoing. Varicella can be lethal to individuals with impaired immunity. It also resulted in reduced immunity and increased thyroid disorders. They are essential for fighting infections and for subsequent immunity. RNAi is a form of antiviral immunity with high specificity. Age distribution of smallpox infections depended on acquired immunity. MALT plays a role in regulating mucosal immunity. Polio vaccination is also important in the development of "herd immunity".