There is an icosahedral configuration in the capsid of the herpes virus. Most people have been infected with at least one of these types of herpes virus. Chromatin dynamics regulate the transcription competency of entire herpes virus genomes. The patients tested positive for the herpes virus. Cytomegalovirus (a type of herpes virus) is what causes cytomegalovirus retinitis. A protein found in neurons may bind to herpes virus DNA and regulate latency. New herpes virus drugs include viral helicase-primase and terminase inhibitors. For this reason, knowledge of these herpes virus conditions was limited to severe cases. Many viruses, e.g. herpes virus, have icosahedral shells. The Tzanck test has been largely replaced by DFA for identification of the herpes virus. A herpes virus is known from black storks. Talimogene laherparepvec is a genetically engineered herpes virus (an oncolytic herpes virus). Each human herpes virus may present differently within the oral cavity. Many viruses, such as the herpes virus, have the shape of a regular icosahedron. HHV-6 (human herpes virus 6) encephalitis is also clinically indistinguishable from limbic encephalitis.