It is a combination of two antiretroviral medications, lamivudine and zidovudine. AZT nucleoside reverse-transcriptase inhibitor (NRTI), zidovudine (AZT) was not effective on its own. It is typically used in combination with other antiretrovirals such as zidovudine and abacavir. The antiviral drug zidovudine (AZT) contains an azido group. The combination of zidovudine with paracetamol can increase the risk of neutropenia. Babies born to HIV-positive women should receive a 6-week or 12-week course of zidovudine (AZT). Drug resistance to didanosine does develop, though slower than to zidovudine (AZT). Its FDA approval helped bring down the price of zidovudine (AZT), the initial anti-HIV drug. Combining zidovudine with stavudine does not increase the mitochondrial toxicity compared to stavudine alone. Typical NRTIs include&colon; zidovudine (AZT) or tenofovir (TDF) and lamivudine (3TC) or emtricitabine (FTC). Lamivudine treatment has been shown to restore zidovudine sensitivity of previously resistant HIV. In particular, diaryl phosphates were prepared from zidovudine (AZT) using simple phosphorochloridate chemistry. Treatment options that have been tried include zidovudine and the CHOP regimen. Study 076 of 100 Zidovudine in maternal-infant transmission of HIV had been published in 1994. Commonly, abacavir is sold together with other HIV medications, such as abacavir/lamivudine/zidovudine, abacavir/dolutegravir/lamivudine, and abacavir/lamivudine.