Such non-sugar sweeteners include saccharin and aspartame. The original formula was sweetened with cyclamate and saccharin. Most artificial sweeteners have been discovered when accidentally tasted, including aspartame and saccharin. It was initially sweetened with a mixture of cyclamate and saccharin. Sodium saccharin (benzoic sulfimide) is an artificial sweetener with effectively no food energy. Others, such as aspartame and sodium saccharin, have much larger variation. The bitter aftertaste of saccharin is often minimized by blending it with other sweeteners. In 1990, Gatorade introduced Gatorade Light, a lower-calorie version sweetened with saccharin. At various times it was sweetened with cyclamates and saccharin. Coffee was replaced by toasted barley mixed with chicory, and sugar with saccharin. In 1911, Food Inspection Decision 135 stated that foods containing saccharin were adulterated. Industrially, anthranilic acid is an intermediate in the production of azo dyes and saccharin. In 1899, the company began producing the sugar substitute saccharin. Epidemiological studies have shown no evidence that saccharin is associated with bladder cancer in humans. The moratorium required a warning label and also mandated further study of saccharin safety.