Vasopressin is administered through an intravenous device, intramuscular injection or a subcutaneous injection. Treatment generally involves calcium injection by intravenous, intramuscular or subcutaneous routes. Naloxone can also be administered via intramuscular or subcutaneous injection. If atropine is given by intramuscular or subcutaneous injection, it causes initial bradycardia. Designs exist for both intramuscular and subcutaneous injection. Methotrexate can be given by mouth or by injection (intramuscular, intravenous, subcutaneous, or intrathecal). Absorption takes the longest from this route compared to intravenous, intramuscular, and subcutaneous injections. Intramuscular, subcutaneous, and transdermal options are available. It is administered to oncology patients via subcutaneous or intravenous routes. This is due to atrophy of the subcutaneous tissue and dermal fibrosis. The most commonly tested methods are subcutaneous and intravenous injections of mice. It is administered by intermittent injections or continuous subcutaneous infusions. It lives in the cutaneous and subcutaneous dermal layer. Insulin injection is a common type of subcutaneous injection medicine. Nerves can be stimulated using either surface (transcutaneous) or subcutaneous (percutaneous or implanted) electrodes.