Another common condition is gastric ulceration, peptic ulcers. Infections are associated with mucosal ulceration, rectal bleeding, and drastic dehydration. These lesions may show ulceration and/or erythema. This progresses to a prolonged inflammatory response causing mucosal (middle ear) oedema, ulceration and perforation. Recurrent ulceration and fat necrosis is associated with lipodermatosclerosis. Adjacent ulcers may merge to form larger, continuous areas of ulceration. It is termed major aphthous ulceration (MaAU) or major recurrent aphthous stomatitis (MaRAS). This subtype is termed minor aphthous ulceration (MiAU), or minor recurrent aphthous stomatitis (MiRAS). A chronically prolapsed rectal tissue may undergo pathological changes such as thickening, ulceration and bleeding. This is followed by considerable swelling, blistering, necrosis, and ulceration. Ulceration or inflammation may be seen on cystoscopy. Hematinic deficiencies can cause anemia, which is also associated with aphthous-like ulceration. Chronic ulceration at this site can cause linear fibrous hyperplasia. Wounds are graded 0 through 3 on the presence of ulceration and/or gangrene and ischemia. Zinc deficiency can manifest as non-specific oral ulceration, stomatitis, or white tongue coating.