Suppressive fire capabilities vary widely because the suppressive effect area varies widely. Suppressive antiviral therapy reduces these risks by 50%. These cytokines may have suppressive effect on production of IgM. Another approach may block their immune suppressive mechanism. People with lower rates of recurrence will probably also have fewer recurrences with suppressive therapy. This indicates that Breg must be stimulated to produce suppressive cytokines. DHHS guidelines do not recommend switching an otherwise suppressive regimen. The primary intended effect of suppressive fire is psychological. Suppressive fire may be direct or indirect. Scientology disconnection policy prohibits most contact with Suppressive Persons. The Scientology organization has continued to aggressively target people it deems suppressive. Those who communicate with Suppressive Persons can face being branded SPs themselves by Scientology. Non-Scientologists can be and have been labelled Suppressive Persons. The heavy gunner is armed with a large four-barreled minigun for suppressive fire. The rifle is fully ambidextrous and possesses flexibility for assault, marksman and suppressive roles.