Eye color is defined by that of the iris. Eye color outside of the iris may also be symptomatic of disease. The anterior segment is made up of the cornea, iris and lens. Deodorants made from alum, iris and rose petals were common. Neither blue nor green pigments are ever present in the human iris or ocular fluid. Lamotrigine binds to melanin-containing tissues such as the iris of the eye. The large eyes have a golden iris and round pupils. The lead single, "Roses/Lotus/Violet/Iris", was released on March 19, 2020. The immature has a dark brown iris and yellowish feet. The color of the human iris is very variable. Effects on the iris and ciliary muscle may persist for longer than 72 hours. Its leaves resembles those of the iris family. Uveal tumors can originate from melanocytes residing within the iris. Whereas, the pupil is the passive opening formed by the active iris. Normally, there is a thick layer of melanin on the back of the iris.