There is a chance of sarcoid recurrence for all modalities even after apparently successful treatment. James's lifetime work on sarcoidosis led him to be known as the "King of Sarcoid". They are also thought to cause the skin tumour equine sarcoid in horses and donkeys. Sarcoid granulomas can resolve spontaneously without complications or heal with residual scarring. Chronic sarcoid arthritis usually occurs in the setting of more diffuse organ involvement. Sarcoid has tight epithelioid granulomas and lymphoid infiltrate. Fiddler's neck can be differentiated from rosacea and sarcoid reaction with granulomas. Cardiac sarcoid has been connected to tumor necrosis factor alpha (TNFA) variants.