Surgery is curative of mitral valve regurgitation. Signs of mitral and tricuspid regurgitation may be present. Both complications may lead to worsening of mitral regurgitation. Atrial fibrillation may also be noted on the ECG in individuals with chronic mitral regurgitation. The major predictors of mortality are the severity of mitral regurgitation and the ejection fraction. Mitral regurgitation (MR) "decreases" afterload. By far the most serious adverse event is the occurrence of acute severe mitral regurgitation. All had severe eccentric mitral regurgitation (MR). Left ventricle dysfunction determines to an extent the outlook for severity of aortic regurgitation cases. In tricuspid valve regurgitation, these pulsations are very strong. In the United States, MVP is the most common cause of severe, non-ischemic mitral regurgitation. The prevalence of aortic regurgitation also increases with age. Carvallo's sign is a clinical sign found in patients with tricuspid regurgitation. Long term complications most commonly include pulmonary valve regurgitation, and arrhythmias. Most frequently it is applied for the treatment of aortic regurgitation.