Metolachlor induces cytotoxic and genotoxic effects in human lymphocytes. II transmembrane protein expressed on cytotoxic T lymphocytes. Mature dendritic cells activate T helper cells and cytotoxic T cells. IL-12 mediates enhancement of the cytotoxic activity of NK cells and CD8+ cytotoxic T lymphocytes. DCs present antigen to both helper and cytotoxic T cells. Only licensed dendritic cells are able to activate cytotoxic T cells. It has been found to be both cytotoxic and weakly genotoxic in laboratory animals. CD80 is an especially important component in dendritic cell licensing and cytotoxic T-cell activation. Compounds that have cytotoxic effects often compromise cell membrane integrity. Nabilone can be prescribed to treat nausea and vomiting caused by cytotoxic chemotherapy. Such modification induces mutations, which are cytotoxic and carcinogenic. Neutropenia is often caused by extremely cytotoxic medications such as cyclophosphamide. I pathway for induction CD8+ cytotoxic T cells. In this way, it governs the action of cytotoxic lymphocytes. I molecules to CD8 T cells (cytotoxic T cells).