Induced by oxidative stress generated by arsenite treatment. It is required for the detoxification of arsenate, arsenite, and antimonite. Bulk arsenic-based compounds sodium arsenite and sodium cacodylate are derived from the trioxide. This two-subunit enzyme produces resistance to arsenite and antimonite. Examples include diethylstilbestrol, arsenite, hexachlorobenzene, and nickel compounds. It was also proposed that binding of arsenite at nonessential sites might contribute to detoxification. The carcinogenicity of potassium arsenite arises from its ability to inhibit DNA repair and methylation. Solutions of potassium arsenite contain moderate concentrations of hydroxide, and are thus slightly basic. Additionally, both the meta and ortho forms of potassium arsenite have identical properties. The toxic compounds in arsenic are arsenate and arsenite. Sodium arsenite can be inhaled or absorbed through the skin. One is when arsenate is reduced to arsenite which adsorbs to iron oxides less strongly. Sb30 cells poorly accumulate arsenite and arsenate. Sodium arsenite usually refers to the inorganic compound with the formula NaAsO. Arsenate reduction and arsenite oxidation have been observed in microbes ("Chrysiogenes arsenatis").