The pathological features of paracoccidioidomycosis are similar to those seen in coccidioidomycosis and blastomycosis. This includes aspergillosis, blastomycosis, coccidioidomycosis, histoplasmosis, and paracoccidioidomycosis. Disseminated granulomatoses such as tuberculosis, histoplasmosis, coccidioidomycosis, blastomycosis and sarcoidosis are associated with FUO. The fungal infections it is used to treat include aspergillosis, blastomycosis, candidiasis, coccidioidomycosis, and cryptococcosis. The evidence is more limited for coccidioidomycosis, measles, smallpox, and varicella. There is a lack of prospective studies that examine optimal anti-fungal therapy for coccidioidomycosis. Posaconazole has been approved by the European Commission as a salvage therapy for refractory coccidioidomycosis. These include aspergillosis, candidiasis, coccidioidomycosis, cryptococcosis, histoplasmosis, mycetomas, and paracoccidioidomycosis. A similar appearance can be associated with histoplasmosis, cryptococcosis, and coccidioidomycosis. Typical examples of sapronotic agents are fungal such as coccidioidomycosis, histoplasmosis, aspergillosis, cryptococcosis, "Microsporum gypseum". Less common causes include aspergilloma, bronchiectasis, coccidioidomycosis, pulmonary embolism, pneumonic plague, and cystic fibrosis. "C. immitis" can cause a disease called coccidioidomycosis (valley fever). This includes aspergillosis, candidiasis, coccidioidomycosis, histoplasmosis, penicilliosis, and infections by "Scedosporium" or "Fusarium". The causative agents of coccidioidomycosis are "Coccidioides immitis" and "Coccidioides posadasii". Valley fever may progress to the chronic form and then to disseminated coccidioidomycosis.