The medial prefrontal cortex processes egocentric spatial information. Pyramidal neurons in the prefrontal cortex are implicated in cognitive ability. Mirtazapine increases dopamine release in the prefrontal cortex. Other theories implicate the prefrontal cortex. People that exhibit antisocial behavior demonstrate decreased activity in the prefrontal cortex. This includes changes in the prefrontal cortex and the amygdala. The OFC is considered anatomically synonymous with the ventromedial prefrontal cortex. Alcohol creates deficits on the function of the prefrontal cortex. The limbic system is also tightly connected to the prefrontal cortex. Patients with damage to the ventromedial prefrontal cortex have difficulty making advantageous decisions. Older protocols that targeted the prefrontal dorsal cortex were less successful. This system projects to the limbic system and the prefrontal cortex. In blunted affect, there are abnormalities in circuits that also include the prefrontal cortex. Conceptual priming has been linked to reduced blood flow in the left prefrontal cortex. PTSD can be attributed to the functional impairment of the prefrontal cortex (PFC) structure.