This was not helped by a niggling injury requiring cortisone injections. The enhanced adrenocorticoid activity of these compounds over cortisone and hydrocortisone was demonstrated in mice. Efforts may be used to try to speed hair regrowth such as cortisone injections. The plant contains a steroid which is important to the production of cortisone. In order to reduce inflammation, creams and salves containing cortisone are often very effective. The skin lesions sometimes cause itching, which can be treated by applying cortisone cream. Itching may be improved by applying a cortisone cream. They treated the injury through draining fluid and injecting cortisone. Koufax ended up getting three cortisone shots for his sore elbow, and missed three starts. After a cortisone injection, he recovered sufficiently to go on stage. The required usage of cortisone over time resulted in him having Cushings syndrome. The efficacy of cortisone and laser treatment is disputed. Bupropion is metabolized to threo-hydrobupropion via cortisone reductase. His foot was injured during the tournament, and he played through, taking some cortisone shots. The discovery of cortisone allowed survival of infants with severe CAH for the first time.