There are few contraindications to bone marrow examination. MSCs are obtained by aspiration of bone marrow. Basophils arise and mature in bone marrow. It may be toxic to bone marrow. It is composed of cells derived primarily from the myeloid compartment of bone marrow differentiation. Donna died in 2015 of bone marrow cancer. Granulocytes are derived from stem cells residing in the bone marrow. All MPNs arise from precursors of the myeloid lineages in the bone marrow. Granulocytes are produced via granulopoiesis in the bone marrow. All are used to examine blood or bone marrow samples. Medical imaging may provide a limited amount of information regarding bone marrow. Diagnosis of myelofibrosis is made on the basis of bone marrow biopsy. Finally, he underwent conventional treatments of chemotherapy and bone marrow transplantation. It should not be used in those with a history of bone marrow problems. Dysplasia can affect all three lineages seen in the bone marrow.