As they are photographed in their prison uniforms, Holly realises that he's buggered up again. I liken our struggle to getting buggered over, and over, and over again. She is listed as #31 in Quentin Letts' book, "50 People Who Buggered Up Britain". "I'm buggered" can also be used to indicate a state of fatigue. It's time that Pistol and Boo [the dogs] buggered off back to the United States.