Granulocytes include basophils, eosinophils, neutrophils, and mast cells. Myeloid cells include monocytes, macrophages, neutrophils, basophils, eosinophils, erythrocytes, and megakaryocytes to platelets. Neutrophils, macrophages, monocytes, dendritic cells, osteoclasts and eosinophils can be classified as professional phagocytes. The VCAM-1 protein mediates the adhesion of lymphocytes, monocytes, eosinophils, and basophils to vascular endothelium. GM-CSF stimulates stem cells to produce granulocytes (neutrophils, eosinophils, and basophils) and monocytes. Phagocytic cells such as neutrophils, eosinophils, and mononuclear phagocytes produce ROS when stimulated. These include lymphocytes, neutrophils, eosinophils, multinucleated giant cells, fibroblasts and collagen (fibrosis). The increased expression of chemokines attracts other cells including neutrophils but not eosinophils. In this category are neutrophils, mast cells, basophils, and eosinophils. Fc receptors are also found on eosinophils, monocytes, macrophages and platelets in humans. Neutrophils, along with eosinophils and basophils, make up the category of granulocytes. Basophils and eosinophils are related to neutrophils. This subepidermal region showed an increased infiltration of eosinophils and lymphocytes. Neutrophils and eosinophils bind to E-selectin. Basophils can also release chemical signals that attract eosinophils and neutrophils to an infection site.