The drug is approved for patients with lymphoma and multiple myeloma. Bisphosphonates can also reduce mortality in those with multiple myeloma and prostate cancer. It is also expressed on malignant plasma cells in multiple myeloma. I clinical trial on patients with multiple myeloma. This stage is referred to as relapsed/refractory multiple myeloma (RRMM). CD38 is overexpressed in multiple myeloma cells. Other treatments can involve application of chemotherapy similar to that used in multiple myeloma. Among patients with multiple myeloma, RANKL activity was greatly increased. The anemia found in myeloma is usually normocytic and normochromic. Occasionally the monoclonal proteins produced by myeloma patients can be anti-dsDNA. CD20 positive cells are also sometimes found in cases of Hodgkins disease, myeloma, and thymoma. It binds to CD38, which multiple myeloma cells overexpress. There are two types of stem cell transplants to treat multiple myeloma. The plasma cells seen in multiple myeloma have several possible morphologies. The fusion of the B cells with myeloma cells can be done using electrofusion.