The putamen and caudate nucleus together form the dorsal striatum. The dorsal striatum consists of the caudate nucleus and the putamen. The dorsal striatum is composed of the caudate nucleus and the putamen. Calcifications in the caudate, dentate nuclei, putamen and thalami are also common. Along with the caudate nucleus it forms the dorsal striatum. With the caudate nucleus, it forms the striatum. The striatum is made up of the caudate nucleus and the lentiform nucleus. Necropsy shows loss of neurons and gliosis in the caudate and globus pallidus. The amygdala sends direct projections to the caudate nucleus. Reward Dependence correlated with decreased grey matter volume in the caudate nucleus. Both the temporal lobe and the caudate nucleus were found to be enlarged. Projections from the caudate nucleus to the superior colliculus also modulate saccadic eye movement. It is associated with lesions in the left caudate nucleus. The caudate nucleus integrates spatial information with motor behavior formulation. Neurons in some parts of the caudate nucleus also show activity related to eye movements.