Various species are important pharmacologically as a source of the parasympathomimetic alkaloid Pilocarpine. Sweat testing involves application of a medication that stimulates sweating (pilocarpine). Medical treatment in 1880 included the use of intravenous doses of a drug called pilocarpine. Saliva production may be pharmacologically stimulated by sialagogues such as pilocarpine and cevimeline. Sweating is then encouraged by increased room temperature, exercise, use of a sauna, or pilocarpine. A normal pupil will not constrict with the dilute dose of pilocarpine. Pilopine HS (Alcon), Salagen (MGI Pharma), Scheinpharm Pilocarpine (Schein Pharmaceutical), and Timpilo (Merck Frosst). Can also be used in adjunctive therapy with pilocarpine or carbonic anhydrase inhibitors. The antidote to atropine is physostigmine or pilocarpine. Intravenous injection of pilocarpine to induce bronchospasm was followed by intravenous injection of the agonists. In the other 25%, laser iridoplasty, medication (pilocarpine) or incisional surgery may be required. These include artificial saliva, pilocarpine, zinc supplementation, alterations in drug therapy, and alpha lipoic acid. Pilocarpine is in the miotics family of medication. Pilocarpine drops may be administered as a treatment as well as a diagnostic measure. The antidote for belladonna poisoning is physostigmine or pilocarpine, the same as for atropine.