The onset of a manic or depressive episode is often foreshadowed by sleep disturbances. Lithium is the classic mood stabilizer to prevent further manic and depressive episodes. Thus, the proposed surgical intervention for psychotic or manic behavior was bloodletting. Wilson is diagnosed as a schizoaffective with mild manic depression. Hypomanic episodes rarely progress to full-blown manic episodes. Norman Osborn is shown to be severely manic depressive. Greene suffered from manic depression (bipolar disorder). Valproate products are also used to treat manic or mixed episodes of bipolar disorder. Stewart recalls he was in a manic mood while Lennox was depressed. Lyrically, it deals with the singer's struggles with bipolar disorder (previously known as manic depression). Dr. Goudron is portrayed as manic, insane, unreliable. Brett was prescribed lithium tablets to fight his manic depression. Some people have reported relief from depression or manic symptoms after theft. Rubidium was tested for the influence on manic depression and depression. As early as 1953, Soviet doctors diagnosed Lin as suffering from manic depression.