They are injected with a catheter needle inserted into the varix through the endoscope. An upper endoscopy is a procedure to look at the esophagus by using an endoscope. A tiny incision is made on the esophageal mucosa through which an endoscope is inserted. The disease is diagnosed by biopsy done by an endoscope (a fiberoptic camera). An endoscope is inserted in one incision to guide the physician. A hysteroscope is an endoscope that carries optical and light channels or fibers. GAVE is treated commonly by means of an endoscope, including argon plasma coagulation and electrocautery. Alternatively, a simple USB device can be fitted to a conventional endoscope. The endoscope is gradually advanced down the esophagus making note of any pathology. Basil Hirschowitz and Larry Curtiss invented the first fiber optic endoscope in 1957. In combination with an endoscope this technique is used for intraoperative diagnosis of brain tumors. So were the stethoscope, the electrocardiograph, and the endoscope. A flexible endoscope can be of no help with large and jammed objects. Another method of examination of the stomach, is the use of an endoscope. The first flexible Endoscope in the world was co-developed and manufactured by Olympus in Tokyo.