His laboratory works on the genetic characterization and clinical description of monogenic conditions in humans. Note on isozyme pattern of monogenic recessive vegetative mutant in rice. An example of a number field that is not monogenic was first given by Dedekind. These models have been extensively annotated with gene homologs of several monogenic disorders in humans. This process call be applied to any monogenic disease. A semigroup generated by a single element is said to be monogenic (or cyclic). Individuals with monogenic diabetes can pass it on to their children or future generations. A considerable number of monogenic disorders can be found especially among patients with VEOIBD. The process is often used when screening for monogenic disorders, such as cystic fibrosis. GRA appears to be the most common monogenic form of human hypertension. Unlike monogenic traits, polygenic traits do not follow patterns of Mendelian inheritance (discrete categories). Nephronophthisis is the leading monogenic cause of end-stage kidney disease. Monogenic functions are special cases of harmonic spinors on a spin manifold. A single-gene disorder (or monogenic disorder) is the result of a single mutated gene. Solutions to the euclidean Dirac equation "Df" = 0 are called (left) monogenic functions.