The binding typically results in a change of conformational isomerism (conformation) of the target protein. The USEF breed standard requires Arabians have solid bone and standard correct equine conformation. Many breed registries allow only certain clips for poodles shown in conformation. Prices of Thoroughbreds vary greatly, depending on age, pedigree, conformation, and other market factors. There are several disqualification criteria in the breed standard for the purpose of conformation showing. The adamantane molecule consists of three condensed cyclohexane rings fused in the armchair conformation. The shape into which a protein naturally folds is known as its native conformation. It produces alterations in the physiochemical properties including changes in conformation, electrostatic binding, hydrophobicity etc. Dihedral angles are used to specify the molecular conformation. For conformation showing, symmetrical markings are preferred. It assists in determining structure and conformation changes over time. It can exist in a disordered amorphous conformation or two different helical forms. Thus, all subunits must exist in the same conformation. The hydration layer plays a vital role in sustaining solubility and suitable natural conformation. These interactions can be determined by bioinformatic analysis of chromosome conformation capture experiments.