Clothianidin is an alternative to organophosphate, carbamate, and pyrethroid pesticides. It has helped prevent insect pests build up resistance to organophosphate and pyrethroid pesticides. There is substantial evidence of associations between organophosphate insecticide exposures and neurobehavioral alterations. Symptoms such as muscle weakness seem to be similar to organophosphate insecticide exposure. PON1 is responsible for hydrolysing organophosphate pesticides and nerve gasses. Pyridinecarbaldehydes are used to make antidotes for poisoning by organophosphate acetylcholinesterase inhibitors. As nerve agents, the Novichok agents belong to the class of organophosphate acetylcholinesterase inhibitors. It is the processor for production of the organophosphate insecticide Terbufos. The phosphorylation of cholinesterase by TEPP (or any other organophosphate) is irreversible. It provides fragrance to various products and as an odor-masking agent for some organophosphate pesticides. Currently atropine is administered intraveinously to treat bradycardia and as an antidote to organophosphate poisoning. Atropine is not an actual antidote for organophosphate poisoning. BCHE can be used as a prophylactic agent against nerve gas and other organophosphate poisoning. A number of measurements exist to assess exposure and early biological effects for organophosphate poisoning. Pralidoxime is only effective in organophosphate toxicity.