Imidacloprid is neither carcinogenic in laboratory animals nor mutagenic in standard laboratory assays. Studies showed no evidence of teratogenic or mutagenic effects. These compounds have also not been shown to have any direct mutagenic or genotoxic activity. AES has not been found to be genotoxic, mutagenic, or carcinogenic. This may put these organisms at risk of mutagenic, teratogenic, and/or carcinogenic effects. However, arbutin acts as quercetin extremely mutagenic, carcinogenic and toxic. Styrene oxide is considered toxic, mutagenic, and possibly carcinogenic. Dioctyl sodium sulfosuccinate is not known to be carcinogenic, mutagenic, or teratogenic. Triacetylethylenediamine is not mutagenic and not teratogenic. It is largely agreed that TCDD is not mutagenic or genotoxic. Salmon calcitonin is devoid of embryotoxic, teratogenic, and mutagenic potential. In addition, it is strongly mutagenic and carcinogenic, due to its alkylating properties. Tar includes the majority of mutagenic and carcinogenic agents in tobacco smoke. REACH considers three toxic classes&colon; carcinogenic, reproductive, and mutagenic capacities. Imidacloprid is moderately toxic and is linked to neurotoxic, reproductive and mutagenic effects.