Amoeba and other protists serve as natural hosts. Tests showed "Naegleria fowleri", a dangerous amoeba, in the water. "Naegleria fowleri" is also known as the "brain-eating amoeba". Ingested red blood cells are sometimes seen in the amoeba cell cytoplasm. Food enveloped by the "Amoeba" is stored in digestive organelles called food vacuoles. Furthermore, CB can intensify pinocytosis, which is induced by concanavalin A in amoeba proteus. This leads to viral particles to be released into the cytoplasm of the amoeba. The mechanism of infection is similar in amoeba and human cells. This process regulates the amount of water present in the cytoplasm of the amoeba. In mammals and the social amoeba "Dictyostelium discoideum" it is required for phagocytosis. Diloxanide is a medication used to treat amoeba infections. Amoebiasis is an infection caused by the amoeba "Entamoeba histolytica". Fossils of testate amoeba (or Arcellinida) first appear during the Cryogenian period. Iodamoeba buetschlii is a species of amoeba. Other software by Rogue Amoeba includes Nicecast, Airfoil, and Fission.