The increased pressure is caused by trabecular meshwork blockage. The trabecular meshwork is responsible for most of the outflow of aqueous humor. It targets the trabecular meshwork directly. In SLT a laser is used to selectively target the melanocytes in the trabecular meshwork. Trabeculectomy is a guarded filtering procedure that removes of part of the trabecular meshwork. A trabeculoplasty is a modification of the trabecular meshwork. The greatest resistance to aqueous flow is provided by the trabecular meshwork (esp. Thin reticular fibers (reticulin) of reticular connective tissue form a supporting meshwork inside the node. In people with narrow angles, this can uncover the trabecular meshwork. Trabeculopuncture uses a Q switched Nd&colon;YAG laser to punch small holes in the trabecular meshwork. These are flat regions of dense actin meshwork instead of bundled F-actin as in filopodia. Reticular fibers crosslink to form a fine meshwork (reticulin). Fiber forms a reinforcing meshwork in plasters, which helps to hold the plaster together. In animals, spectrin forms the meshwork that provides red blood cells their shape. The regions where there are few cells within the meshwork are known as "lymph sinus".