Pituitary prolactin secretion is regulated by endocrine neurons in the hypothalamus. The hypothalamus and pituitary gland are neuroendocrine organs. The hypothalamus and pituitary glands are neuroendocrine organs. The pituitary gland secretes hormones that are produced in the hypothalamus and itself. The posterior pituitary hormones are synthesized by cell bodies in the hypothalamus. The hypothalamus and pituitary gland are tightly integrated. Beta-endorphins are found in neurons in the hypothalamus and the pituitary gland. These feedback mechanisms are controlled by the hypothalamus and pituitary gland. Satiety in the hypothalamus is stimulated by leptin. It can also be caused by diseases affecting the hypothalamus and pituitary gland. Leptin has receptors in the hypothalamus which synthesizes GnRH. Somatostatin is produced by neuroendocrine neurons of the ventromedial nucleus of the hypothalamus. Messages from the hypothalamus are sent to the pituitary gland. Ghrelin stimulates hunger by triggering receptors in the hypothalamus. Several important feedback systems are mediated via the hypothalamus and pituitary.