They are characteristically "suppurative", i.e., pus forming, containing large numbers of neutrophils. He graduated as a doctor in 1893 with a thesis about suppurative hepatitis. Less common symptoms include pyrexia, anorexia, and joint pain caused by sterile suppurative arthritis. This honeycomb is a painful inflammatory reaction with deep suppurative lesions on the scalp. Cytological analysis of joint fluid often reveals sterile suppurative arthritis.