Complications may include cirrhosis, liver cancer, and esophageal varices. Such dilatation can lead to esophageal varices and anorectal varices. Dilated submucosal veins are the most prominent histologic feature of esophageal varices. An anorectal varices related hemorrhoids caused by cirrhosis, however symptomatic treatment often involves removal. Esophageal varices are typically diagnosed through an esophagogastroduodenoscopy. Other sites of varices, including esophageal varices, duodenal varices and colonic varices. Esophageal varices often do not have symptoms until they rupture. This may lead to ascites or bleeding from varices. TIPS is a life-saving procedure in bleeding from esophageal or gastric varices. These evaluations may detect gastric varices that are asymptomatic. In some cases, schistosomiasis also leads to esophageal varices. Use of vasopressin analogues for esophageal varices commenced in 1970. Others have suggested that the writer's hemorrhage was caused by bleeding from esophageal varices. These veins have no part in the development of esophageal varices. A TEE may be technically difficult to perform in individuals with esophageal strictures or varices.