Are there general principles for assessing the qualitative appropriateness of reciprocal responses? Validity confronts questions over a test's appropriateness and effectiveness for the given purpose. Timing and appropriateness of transplantation remain difficult decisions. International consensus on the appropriateness of data scales and methodologies is pending. The last assumption puts emphasis on social appropriateness and norms. The versions are designated to signal their appropriateness for differing user requirements. Ventriloquism has been used as the evidence for the modality appropriateness hypothesis. The appropriateness of PCI use depends on many factors. Throughout his life Sweeney remained convinced of the appropriateness and necessity of the bombing. His decision created further controversy over the appropriateness of the museum accepting this bequest. There is some debate among statisticians about the appropriateness of so-called "stepwise" procedures. Disagreements persist about the appropriateness of some of the methods of CBS's editors. The appropriateness of such uses has been disputed. The framework states the ability to represent the domain as domain appropriateness. The case is sometimes cited in arguments about the appropriateness of patenting genes.