Agomelatine is contraindicated in patients with kidney or liver impairment. People with liver or kidney problems may need lower doses. Metformin should not be used in those with severe kidney or liver problems. Renal physiology is the study of kidney function. Caution is recommended in those with liver or kidney problems. Care should be taken in those with either kidney or liver problems. A change in dosage may be recommended in those with kidney or liver problems. This happens in some cell types like liver and kidney. Therefore, trimethoprim should be used with caution in individuals with kidney and liver impairments. Renal histology is the study of the microscopic structure of the kidney. Urine analysis in patients with diabetic kidney disease is often bland. Incorporated uranium becomes uranyl ions, which accumulate in bone, liver, kidney, and reproductive tissues. Dialysis may attenuate malnutrition of kidney failure. Acute fluid overload can cause edema in someone with kidney failure. Lower doses are recommended in those with kidney disease associated with a low kidney function.