Azacitidine induces tumor regression on isocitrate dehydrogenase-1 mutant glioma xenografts in mice. Some of the tumors include astrocytoma, glioblastoma, glioma, and subependynoma. Glioblastoma is an aggressive form of glioma. Swainsonine has a potential for treating cancers such as glioma and gastric carcinoma. It was discovered that the tumor was malignant glioma and was incurable. Iodine-131-TM-601 is used to treat malignant glioma. For example, MMP9 appears to be involved in the remodeling associated with malignant glioma neovascularization. They also show a listing of chemotherapy agents used to treat high-grade glioma tumors. These tumors occur spontaneously ("de novo") or have progressed from a lower-grade glioma, respectively. Diffuse intrinsic pontine glioma primarily affects children, usually between the ages of 5 and 7. This is not for all brainstem glioma, this statistic reflects DIPG. Examples include encephalocele, glioma, inverted papilloma, and cancer. The gel slowly degraded and facilitated sustained release of PTX into the targeted glioma cells. A cancer, such as an optic glioma, may also impact the optic nerve (II). A glioma of the optic nerve can cause visual loss.