Diagnosis is confirmed histologically by tissue biopsy. Diagnosis is by examination of a bone marrow or lymph node biopsy. Diagnosis can be confirmed by tissue biopsy. Definitive diagnosis is by lymph node biopsy (usually excisional biopsy with microscopic examination). Uterine perforation may occur during a D&C or an endometrial biopsy. The diagnosis is confirmed by tissue biopsy. Diagnosis is typically by cervical screening followed by a biopsy. The diagnosis can be confirmed by lung biopsy. Diagnosis may be based on symptoms, medical imaging, lung biopsy, and lung function tests. Definitive diagnosis is based on a tissue biopsy. Diagnosis is by biopsy and histopathological examination. Diagnosis is based on a tissue biopsy. Diagnosis is typically based on urine testing and sometimes a kidney biopsy. GAVE is usually diagnosed definitively by means of an endoscopic biopsy. Rarely, a tissue biopsy or imaging may be required.