Alkaloids such as caffeine, cinchonine, quinine or strychnine, precipitates polyphenols and tannins. Pesticides derived from plants include nicotine, rotenone, strychnine and pyrethrins. Caffeine, as do other alkaloids such as cinchonine, quinine or strychnine, precipitates polyphenols and tannins. Illegal heroin is often mixed with other substances such as sugar, starch, quinine, or strychnine. These include nicotine sulfate, arsenic, and strychnine. All five had died of poisoning, either arsenic or strychnine. Stanford was dead from strychnine poisoning. Jane Stanford died in 1905 after being poisoned with strychnine. The seeds contain more strychnine than other commercial alkaloids. At high doses, it causes convulsions similar to strychnine poisoning. Brucine is not as poisonous as strychnine. It was claimed that Quentin injected him with strychnine rather than a narcotic. She dies, showing the unmistakable symptoms of strychnine poisoning. It can also be caused by poisoning with strychnine or Wilson's disease. Strychnine toxicity in rats is dependent on sex.