It is the simplest of all common aldoses. The Fehling test is a classic method for the detection of aldoses. Aldaric acids are usually synthesized by the oxidation of aldoses with nitric acid. Because they have at least one asymmetric carbon center, all aldoses exhibit stereoisomerism. Like most sugar isomerases, glucose isomerase catalyzes the interconversion of aldoses and ketoses. When added to a solution containing aldoses, a slower forming light pink is observed instead. Examples of aldoses include glyceraldehyde, erythrose, ribose, glucose and galactose. The Wohl degradation in carbohydrate chemistry is a chain contraction method for aldoses. This biological macromolecule consists of 316 residues, and it reduces aldoses, corticosteroids, and aldehydes. Ketoses can isomerize to aldoses through the Lobry-de Bruyn-van Ekenstein transformation. The table shows all aldoses with 3 to 6 carbon atoms, and a few ketoses. Ketoses must first tautomerize to aldoses before they can act as reducing sugars. Like most carbohydrates, simple aldoses have the general chemical formula C(HO). Aldoses react very slowly and give faint colors. Aldehyde monosaccharides may be called aldoses; ketone monosaccharides may be called ketoses.