Patients with adenomyosis often present with painful menses (dysmenorrhea), profuse menses (menorrhagia), or both. Amenorrhea and menorrhagia have been reported as side effects of nandrolone cypionate. Use of intrauterine devices have also shown to reduce menorrhagia and dysmenorrhea. Epistaxis, petechiae and ecchymoses are common symptoms, as are subconjunctival bleeding and menorrhagia. Some patients have spontaneous mucosal bleeding, such as menorrhagia, epistaxis, and gum bleeding. The most common cause for puberty menorrhagia is dysfunctional uterine bleeding. Endometrial ablation devices are used for the treatment of menorrhagia due to dysfunctional uterine bleeding. Gestrinone has also been used to shrink uterine fibroids and to reduce menorrhagia. Excessive menstruation between puberty and 19 years of age is called puberty menorrhagia. Melena, hematemesis, hematuria, menorrhagia or hematochezia point to blood loss. Adult females may experience menorrhagia (heavy periods) due to the bleeding tendency. Some scholars view it as menorrhagia; others as haemorrhoids. In case of puberty menorrhagia due to immaturity of hypothalamic axis, hormonal therapy is beneficial. They are used in menorrhagia and bleeding tendency due to various causes. It may represent a possible endocrine dysfunction, resulting in menorrhagia or metrorrhagia.