Coronary bypass surgery involves bypassing constricted arteries with venous grafts. The layer may help surgeons improve outcomes for patients undergoing corneal grafts and transplants. These capabilities help in surgeries such as transplants, skin grafts, and even reconstructive surgeries. Arteries can also serve as vascular grafts. Pilocarpine is sometimes used immediately before certain types of corneal grafts and cataract surgery. Life-long therapy with co-trimoxazole may be needed for those with prosthetic vascular grafts. The venom produces necrotic lesions that are slow to heal and may require skin grafts. Surgeons have also devoted more attention to the angle and orientation of the transplanted grafts. The earliest is 7 for Rib Cartilage Grafts. This is simple with catheters, but more problematic with fistulas or grafts. Often immunosuppression is required with these grafts. Research dedicated to alternative skin grafts is currently within the purview of tissue engineering. Experiments with nerve grafts have been tried. Full thickness skin grafts are more acceptable cosmetically. The thieves sold the bones for use as medical-grade bone grafts.