The pacing electrode is advanced through the vein under fluoroscopic and electrocardiographic guidance. Bramwell was put in charge of the newly established electrocardiographic department. The serum potassium concentration at which electrocardiographic changes develop is somewhat variable. Electrocardiographic changes are not seen so often. Rarely, hypotonia, dry mouth, urinary incontinence and nonspecific electrocardiographic ST segment changes occur. Catecholamine medications have been studied to mediate the effects of electrocardiographic changes and heart damage. Diminution of T waves has been noticed on routine electrocardiographic recordings. These electrocardiographic markers have subsequently been used clinically on humans. In 1935 he described the electrocardiographic changes of pulmonary embolism. Larger doses produce some side effects, but no electrocardiographic changes are observed in any doses. Another important diagnostic electrocardiographic sign in acute pericarditis is the Spodick sign. Electrocardiographic abnormalities were noted to be common, the most common being sinus bradycardia. Six of these 12 patients displayed the electrocardiographic "myocardial infarction-like" pattern. His company put together the nation's first central electrocardiographic system at Northwestern University Medical School. The earliest electrocardiographic (ECG) findings, associated with hypokalemia, are decreased T wave height.