Genome sequencing and other technologies transformed cichlid taxonomy. The introduction of whole genome sequencing may have ethical implications. Gene typing is different from gene sequencing and serotyping. Unenriched sequencing libraries often have abundant undesired sequences. The result is sequences of quantities and lengths comparable to Illumina sequencing. PCR amplicon sequencing and hybrid capture sequencing. Most p53 mutations are detected by DNA sequencing. The 16S groups have been confirmed by whole genome sequencing (see figure). Prior to the advent of DNA sequencing, cladistic analysis primarily used morphological data. This may be accomplished by means of PCR, restriction fragment analysis and/or DNA sequencing. RNA sequencing was one of the earliest forms of nucleotide sequencing. It pursues research in areas related to proteomics, DNA Sequencing, and drug discovery. Algorithms have been developed for base calling for the various experimental approaches to DNA sequencing. Dideoxynucleotides are useful in the sequencing of DNA in combination with electrophoresis. Basic technologies include reading and writing DNA (sequencing and fabrication).