After food intake the blood sugar concentration increases. IC value increases as agonist concentration increases. An oxygen optode is a sensor based on optical measurement of the oxygen concentration. This is similar to the effect of increasing the concentration of a solution. Urine contains a lower solute concentration than seawater. Hyponatremia is a low sodium concentration in the blood. Variations in atmospheric oxygen concentration have shaped past climates. Hypokalemia (low blood potassium concentration) often follows treatment. A given temperature corresponds to a particular sugar concentration. This results in a lower peak plasma concentration. Conductivity is proportional to the product of mobility and carrier concentration. There were periods of both opposition to market concentration and relative tolerance of cartels. This is a nonlinear dependence between plasma concentration and dosage. Both are necessary to achieve the required concentration. These may include the maximum allowable concentration of , and .