Dosages are titrated to target blood levels. Alternatively, anionic surfactants such as sodium lauryl sulfate can be titrated with cetyl pyridinium chloride. He titrated mercurous solution with potassium chloride, potassium bromide, and potassium iodide. A methyl orange indicator is added and the solution is titrated using alcoholic potassium hydroxide. The sample solution is titrated with alcoholic hydrochloric acid. The dosage may vary and is titrated to effect. In patients with sepsis, the vasopressor dosage may be titrated based on estimated MAP. The dose should be titrated during this overlap period as well. Grignard reagents may be similarly titrated. The iodine liberated is titrated with sodium thiosulphate. This may be titrated with standard sodium tetraphenylborate. Nickel can be titrated thermometrically using di-sodium dimethylglyoximate as titrant. The sample solution is titrated against a solution of silver nitrate of known concentration. Beta blockers are readily titrated to optimal rate control in many pathologic states. In both cases, Fe ions will be titrated subsequently.