Observable symptoms may develop such as polydipsia, polyuria, extreme fatigue, or constipation. Symptoms and signs include abdominal discomfort, polyuria, polydipsia, incidental discovery of hypertension, abdominal mass. These may be followed by polyuria, polydipsia, weakness, insomnia, nervousness, pruritus and ultimately kidney failure. Hyposecretion of insulin results in diabetes mellitus; cardinal signs are polyuria, polydipsia, and polyphagia. This leads to polyuria, dehydration, and polydipsia. With increased thirst, the person now experiences a polydipsia and polyuria cycle. After birth, the infant is seen to urinate and drink excessively (polyuria, and polydipsia, respectively). He excised the pancreas of a neighbour's hunting dog, causing polyuria and polydipsia. Specifically, other more common causes of polyuria and polydipsia are ruled out. Urination imbalance may lead to polydipsia or excessive thirst to prevent circulatory collapse. Psychogenic polydipsia individuals with schizophrenia is associated with differences seen in neuroimaging. Furthermore, enalapril is an emerging treatment for psychogenic polydipsia. Treatment for psychogenic polydipsia depends on severity and may involve behavioural and pharmacological modalities. Although primary polydipsia is usually categorised as psychogenic, there are some rare non-psychogenic causes. Some forms of polydipsia are explicitly non-psychogenic.