Bovine spongiform encephalopathy (BSE), is a neurodegenerative disease of cattle. It is a transmissible spongiform encephalopathy, caused by proteins called prions. A bovine spongiform encephalopathy outbreak was the most publicized. Chronic wasting disease (CWD) is a transmissible spongiform encephalopathy (TSE) affecting deer. He conducted an inquiry into the outbreak of bovine spongiform encephalopathy. It is a type of transmissible spongiform encephalopathy (TSE). For cattle, tissue samples are tested for the presence of bovine spongiform encephalopathy. In the 1980s and 1990s, bovine spongiform encephalopathy spread in cattle in an epidemic fashion. It was then recognized as a transmissible spongiform encephalopathy in 1978. Not until 1988 was the neuropathology of spongiform encephalopathy properly described in cows. In late 2001, a domestic bovine spongiform encephalopathy (BSE) incident critically damaged beef bowl sales. Transmissible spongiform encephalopathies (TSE) are very rare but can reach epidemic proportions.