Standard treatment is surgery with adjuvant chemotherapy and radiotherapy. Invasive thymomas may require additional treatment with radiotherapy and chemotherapy (cyclophosphamide, doxorubicin and cisplatin).. In testicular cancer, adjuvant either radiotherapy or chemotherapy may be used following orchidectomy. Development of secondary neoplasia after successful chemotherapy or radiotherapy treatment can occur. Advanced Hodgkin disease requires systemic chemotherapy, sometimes combined with radiotherapy. Common treatments include surgery, chemotherapy, and radiotherapy. They can be treated with surgical resection, chemotherapy, radiotherapy or a combination. It may also be used for certain outpatient treatments like chemotherapy and radiotherapy treatments. Radiotherapy and chemotherapy reduced tumor and beta-hCG levels normalized. Proton therapy is a type of external beam radiotherapy that uses ionizing radiation. The traditional treatment of NHL includes chemotherapy, radiotherapy, and stem cell transplants. Postoperative (adjuvant) thoracic radiotherapy generally should not be used after curative-intent surgery for NSCLC. The subspecialty of oncology concerned with radiotherapy is called radiation oncology. It showed a small but clear improvement from using chemotherapy with radiotherapy. Evidence for brachytherapy, however, is less than that for external beam radiotherapy.