Uninucleated trophozoites convert into cysts in a process called encystation. Unknown signals within the gastro-intestinal tract trigger encystation. Cycles through somatic hyphae, zoosporangium, zoospores, encystation & germination, and back to somatic hyphae. In the lumen, trophozoites may disintegrate or undergo encystation. After inducing encystation in "E. invadens", DNA replication increases initially and then slows down. Once encystation occurs, the infective cysts are excreted into the environment. The development of a capillary network around the nurse cell completes encystation of the larva. The process is called "encystation" and it continues as long as the mollusc lives. While encystation is yet to be completely defined in "Entamoeba", scientists are getting close.