Metaphase chromosomes make the classical picture of chromosomes (karyotype). The standard diagnostic method is the analysis of the chromosomes' karyotype on lymphocytes. The karyotype of humans includes only 46 chromosomes. It is detected on cytogenetics or a karyotype of affected cells. The initial karyotype includes a set of chromosomes from 2n = 44. The technique of determining the karyotype is usually called "karyotyping". The number of chromosomes in the karyotype between (relatively) unrelated species is hugely variable. This is known as Swyer syndrome, characterized by an XY karyotype and a female phenotype. Any variation from the standard karyotype may lead to developmental abnormalities. She made key findings regarding corn's karyotype, including the size and shape of the chromosomes. Klinefelter syndrome is an example of human polysomy X with the karyotype 47, XXY. Lymphocytes cultured with phytohaemagglutinin can be used for karyotype analysis. KS is diagnosed by the genetic test known as a karyotype. A typical male karyotype is XY, whereas a females is XX. A karyotype is done to diagnose XXYY syndrome.