Hartung believed that he had an eye ailment known as trachoma and quartan malaria. Hippocrates described periodic fevers, labelling them tertian, quartan, subtertian and quotidian. Specifically in the case of quartan fever, the rupturing of liver stage schizonts releases merozoites. The female "Anopheles" mosquito is a vector which transmits quartan fever to people. Several treatments are listed for quartan fever ("quartanis", probably malaria). For quartan fever, "P. malariae" has a prepatent period ranging from 16-59 days. Quartan malaria infects the liver, spleen, and stomach, causing the victim intense pain.