Conditions for hydroformylation catalysis can induce degradation of supporting organophosphorus ligands. Other applications include organophosphorus compounds in detergents, pesticides, and nerve agents. More reactions are found in organosilicon chemistry, organosulfur chemistry, organophosphorus chemistry and organofluorine chemistry. These compounds are some of the most thermally stable organophosphorus compounds. Poisoning by organophosphorus compounds can be treated and acute symptoms are able to be alleviated. Soman is an organophosphorus nerve agent with a mechanism of action similar to Tabun. Some organophosphorus compounds can fatally block certain enzymes in the human body. It is used in medicine and as an organophosphorus insecticide. Like other organophosphorus nerve agents, VX may be destroyed by reaction with strong nucleophiles. It can be used as a sarin-simulant for the calibration of organophosphorus detectors. Triphos is the name for certain organophosphorus ligands. VX is an extremely toxic synthetic chemical compound in the organophosphorus class, specifically, a thiophosphonate. Compounds with P-C and P-O-C bonds are often classified as organophosphorus compounds. The definition of organophosphorus compounds is variable, which can lead to confusion. Novichok was referred to in a patent filed in 2008 for an organophosphorus poisoning treatment.