All of them helped Grace keep whatever shreds of sanity she had left. Since the early 1990s, Jericho has gone through periods of both sanity and insanity. He then decides to fight Doctor Octopus, allowing him to regain his sanity. I really did have doubts about my sanity. Had the time of my life as part of Sanity!! Dobbs is particularly susceptible and begins to lose his sanity to paranoia. Kaashi is put in a psychiatric facility where he starts questioning his own sanity. Derek thinks Sarah is losing her sanity. The character Deadpool is famous for his blatant lack of sanity. Keys felt being on her own was "necessary" for her sanity. His regular pranks on Gareth are one of his ways of maintaining his sanity. I think his character and his own sanity are an issue here. Doctors used this technique in hoping to bring their patients back to sanity. His very sanity had been called into question. His intelligence has been enhanced to gifted levels, though at the price of his sanity.