Treatment may include surgery, radiation therapy, chemotherapy, immunotherapy, and targeted therapy. In addition, BGB324 enhances sensitivity to various therapies including chemotherapy, immunotherapy and several targeted therapeutics. Treatment regimens involving immunotherapy have yielded variable results. Interferon gamma is not approved yet for the treatment in any cancer immunotherapy. It may include some combination of surgery, radiation therapy, chemotherapy, or immunotherapy. Immunotherapy or vaccination for the amyloid protein is one treatment modality under study. In those with significant symptoms, chemotherapy or immunotherapy may be used. Administering monoclonal antibodies (mAbs) is a form of passive immunotherapy. Desensitization via oral immunotherapy is considered experimental. It must be combined with surgery, radiation, chemotherapy or immunotherapy. Animal testing has indicated possible applications in the development of vaccines and cancer immunotherapy. These mutations potentially create new targetable antigens (neoantigens) for use in T cell immunotherapy. Chimeric antigen receptors (CARs) have been developed as a promising immunotherapy for ALL. The benefits of allergen immunotherapy for food allergies is unclear, thus is not recommended . Allergens may also be applied under the tongue as a part of allergen immunotherapy.