Cyclosporine inhibits TOR and is used as an effective immunosuppressant. In multiple clinical trials, vitamin E lowered blood concentration of the immunosuppressant medication, cyclosporine A. The name tacrolimus is derived from "Tsukuba macrolide immunosuppressant". Development of an immunosuppressant drug, cyclosporine A, made transplants a more viable option for patients. Dexamethasone has anti-inflammatory and immunosuppressant effects. One principal reason for transplant rejection is non-adherence to prescribed immunosuppressant regimens. Fludarabine is a drug normally used to treat hematological malignancies and acts as an immunosuppressant. There are many lymphoproliferative disorders that are associated with organ transplantation and immunosuppressant therapies. This eventually led to its FDA approval as an immunosuppressant following kidney transplantation. If symptoms are alleviated by immunosuppressant drugs, such as Prednisone, an allergy-related cause is likely. Thus, it is used as an immunosuppressant following organ transplantation. The medication can be an anti-inflammatory or an immunosuppressant. To prevent this immunosuppressant drugs are used. Everolimus is used in drug-eluting coronary stents as an immunosuppressant to prevent restenosis. It acts as an anti-inflammatory and immunosuppressant.