Hemichromes form an insoluble macromolecule (macromolecular aggregate) by copolymerization with the cytoplasm of band 3. The four groups of macromolecule are nucleic acids, proteins, carbohydrates and lipids. The hydrodynamic radius of a macromolecule or colloid particle is formula 1. Lignin is a complex polyphenolic macromolecule composed mainly of beta-O4-aryl linkages. Nestin is an intermediate filament (IF) protein that assists with IF polymerization and macromolecule stability. The macromolecule or colloid particle is a collection of formula 2 subparticles. Discovery Studio is a suite of software for simulating small molecule and macromolecule systems. A mimotope is a macromolecule, often a peptide, which mimics the structure of an epitope. Transpeptidases cross link the chains and form a net-like peptidoglycan macromolecule. Hydrodynamic radius, "R", can refer to the Stokes radius of a polymer or other macromolecule. The Doppler shift is proportional to the electrophoretic mobility of a macromolecule. The depression of metabolic rate during aestivation causes a reduction in macromolecule synthesis and degradation. In British English, the word "macromolecule" tends to be called "high polymer". A dendrimer is a highly branched macromolecule with a spherical shape. An isotactic macromolecule consists of 100% meso diads.