Flowers of heterozygous plants have a phenotype somewhere between the two homozygous genotypes. Zygosity can either be heterozygous or homozygous. Mice in both the homozygous and heterozygous states develop the seizure phenotype and ataxia. In humans, gene knockouts naturally occur as heterozygous or homozygous loss-of-function gene knockouts. One affected family has been identified with individuals both homozygous and heterozygous for MEN1 mutations. They display dosage (react more strongly to homozygous cells versus heterozygous cells). The homozygous dominant form is more severe than the heterozygous form. Pp (heterozygous), and pp (homozygous recessive). Neither individuals with the homozygous or heterozygous form should take iron supplements. The study found that western lowland gorillas are more likely to be heterozygous than homozygous. Those that are heterozygous have one dominant and one recessive allele. However, one needs to distinguish between heterozygous and homozygous KOs. Almost all patients are heterozygous for mutations. However, the same mutation also conveyed advantages, providing improved viability for heterozygous individuals. This is consistent with a heterozygous or balancing selection coefficient for these loci.