Fragmentation of a molecule can take place by a process of heterolysis or homolysis. Bond cleavage is also possible by a process called heterolysis. An unusually shifted product is formed because the intermediate undergoes heterolysis at the C-Cl position. They found that the rate of heterolysis depends strongly on the nature of the solvent. The polarizability, nucleophilicity and cohesion of the solvent had a much weaker effect on heterolysis. Asymmetric scission of a bond is called heterolysis. In biology, heterolysis refers to apoptosis induced by hydrolytic enzymes from surrounding (usually inflammatory) cells.