Peptic ulcer disease may be intractable and complicated. Persistent digital rectal massage has also been proven effective in terminating intractable hiccups. This study was then repeated with 8 patients with chronic intractable pain. Boundaries between tractable and intractable cases have been an active area of research. It is a difficult but not intractable problem. This method was tested in three pediatric patients with intractable epilepsy, with encouraging clinical results. Governing Scotland became increasingly difficult, as the powerful nobility became increasingly intractable. Others also report fever, respiratory problems and intractable vomiting. It is typically used as a last resort measure in treatment of intractable epilepsy. It remained a treatment of last resort in children with intractable seizures. RSA is based on the assumption that factoring large integers is computationally intractable. This makes general HJM models computationally intractable for most purposes. Intrathecal saline infusion is used in urgent cases such as intractable pain or decreased consciousness. However, such systems tend to be analytically intractable. A more intractable problem was repeated engine failures.