These include oily skin, acne, seborrhea, hirsutism, scalp hair loss, and hidradenitis suppurativa. Acquired hypertrichosis and hirsutism are more common. Some of these uses include acne, seborrhea, hirsutism, and pattern hair loss in women. Some women with hirsutism, a hormonal condition of excessive hairiness, may develop a beard. Vellus hair can also be found in men with male pattern baldness or with hirsutism. Increases in androgen (male hormone) levels are the primary cause of most hirsutism cases. It may be able to improve androgen-dependent symptoms such as acne and hirsutism. However, PCOS and idiopathic hirsutism make up 90% of cases. Spironolactone was first studied in the treatment of hirsutism in women in 1978. One side effect is hirsutism (in women) because of the excess androgen precursors created. Patterns of menstruation are examined since irregular patterns may appear with hirsutism. Females are diagnosed based on the presentation of symptoms that include hirsutism and menstrual irregularities. They can be used to treat symptoms of hyperandrogenism like acne and hirsutism. Some clinical signs of Cushing's disease include obesity, moon face, and hirsutism. Other studies using finasteride for hirsutism have also found it to be clearly effective.