In 2018, UMPS CARE participation was expanded to include Minor League Baseball umpires. In mammals, this bifunctional enzyme UMPS converts orotic acid into uridine monophosphate (UMP). Orotic aciduria can be diagnosed through genetic sequencing of the UMPS gene. That wasn't one of the young umps. He has participated in UMPS CARE charity events. UMPS exists in various forms, depending on external conditions. Both, CAD and UMPS are localized around the mitochondria, in the cytosol. In one study of three patients, UMPS activity ranged from 2-7% of normal levels.