Nystatin A (or referred to as nystatin) is biosynthesized by a bacterial strain, "Streptomyces noursei". For infections of the mouth, treatment with topical clotrimazole or nystatin is usually effective. Nystatin suspension is an antifungal ingredient used for the treatment of oral candidiasis. Antifungal medications such as imidazole, nystatin and natamycin may be used to treat infections. Treatment usually involves the administration of topical nystatin or similar antifungal agents. It is mostly used in complex ointments containing neomycin, nystatin, Thiostrepton and topical steroids. Like many other antifungals and antibiotics, nystatin is of bacterial origin. Trimovate also contains oxytetracycline, an antibiotic, and nystatin, an antifungal. Like amphotericin B and natamycin, nystatin is an ionophore. Amphotericin B, nystatin, and natamycin are examples of polyene antimycotics. Polyene antimycotics, such as amphotericin B, nystatin etc., are a subgroup of macrolides. Nystatin, an antifungal, was sprayed on the wood to prevent mold from growing. Skin, vaginal, mouth, and esophageal "Candida" infections usually respond well to treatment with nystatin. The topically applied azole drugs are more effective than nystatin. If the cause of cracked nipples is from thrush, treatment is usually begun with nystatin.