It disrupts arabinogalactan synthesis by inhibiting the enzyme arabinosyl transferase. This transesterification reaction is catalyzed by carnitine palmitoyl transferase. It can also cause elevations in hepatic enzymes such as gamma-glutamyl transferase and alkaline phosphatase. The first step is the reverse of glycine biosynthesis from serine with serine hydroxymethyl transferase. The reaction is catalyzed by the enzyme UDP-glucuronyl transferase. It activates TST (thiosulfate sulfur transferase) in mitochondria. Aminoacyl transferase binds AMP-amino acid to tRNA. This process is mediated by a specialized enzyme called DHHC palmitoyl transferase. Normetanephrine is a metabolite of norepinephrine created by action of catechol-O-methyl transferase on norepinephrine. The enzyme, originally called "telomere terminal transferase," is now known as telomerase. It is also capable of primase, DNA and RNA polymerase, and terminal transferase activity. The babies have homozygous deficiency of glutathione S transferase (GST) M1. It is closest in sequence to glycine-N-methyl transferase (GNMT). The state of P dictates the activity of adenylyl transferase. An early major breakthrough was the 1,3 galactosyl transferase gene knockout.