Two types of intraductal papillomas are generally distinguished. The relationship is reversed for choroid plexus papillomas. CAPE significantly reduced the number of papillomas. It has been tested in humans with skin papillomas and bladder cancer. There is no evidence that papillomas are premalignant. The first line of treatment is surgery to remove papillomas. Fluorescent antibody study identified the locations of viral antigens in wild rabbit papillomas. Inverted papillomas are definitively diagnosed by histologic examination. Examples include atypical ductal hyperplasia, atypical lobular hyperplasia, and intraductal papillomas. Treatment for laryngeal papillomatosis aims to remove the papillomas and limit their recurrence. Fibrocystic change includes fibroadenomas, fibrosis, and papillomas of the breast. Small growths called papillomas are the most common noncancerous tumors seen with this condition. Like amazon parrots and macaws, cockatoos frequently develop cloacal papillomas. The papillomas can travel past the larynx and infect extralaryngeal sites. The proper name for these structures is pearly penile papules (or hirsutoid papillomas).