In ventilated patients, pulse oximetry it is commonly used when titrating FIO2. Anionic and cationic surfactants can be determined thermometrically by titrating one type against the other. Early attempts at titrating therapy for hypothyroidism proved difficult. The thermoprobe measures the temperature of the titrating solution. Titrating off of a medication instead of stopping abruptly is recommended in some situations. Titrating the dose would be especially important with this compound.