This is indicated by the absence of SRY expression in the mesonephros. The organ is located just in front of the kidney, or mesonephros. It has been suggested that Sertoli cells may derive from the fetal mesonephros. Some of the tubules of the mesonephros form part of the permanent kidney. In females, the mesonephros releases RA, which enters the gonad. Maturation continues as the medial aspect of each mesonephros grows to form the gonadal ridge. The tubules collectively constitute the mesonephros. Cells that will become adrenal tissue move retroperitoneally to the upper portion of the mesonephros. The mesonephros and metanephros of amniotes are derived from different parts of the anamniote opisthonephros. It is formed from the extended mesonephros along with tubules from the posterior nephric ridge. The urogenital ridge is made up of the gonadal anlage and the mesonephros. They are similar to the mesonephros of higher vertebrates (reptiles, birds and mammals). In males, the mesonephros releases retinoic acid. The suspensory ligament originates from the mesonephros, which, in turn, originates from intermediate mesoderm. The duct of the mesonephros forms the Wolffian duct and ureter of the adult kidney.