Further research is required to determine which elimination mechanism succinate undergoes in Succinate Dehydrogenase. Doxylamine is primarily used as the succinic acid salt, doxylamine succinate. It is an inhibitor of succinate dehydrogenase. The binding of succinic dehydrogenase to the substrate, succinate, is competitively inhibited. A combination of paracetamol, codeine, and the calmative doxylamine succinate is also available. Cyanobacteria use electrons from succinate dehydrogenase rather than from NADPH for respiration. SdhE interacts with the catalytic subunit of the succinate dehydrogenase (SDH) complex. It is formed by the oxidation of succinate by the enzyme succinate dehydrogenase. In addition, the efficacy of doxycycline and erythromycin succinate may be reduced by alcohol consumption. They couple this reaction with the oxidation of acetate, succinate or other organic compounds. In living organisms, primarily succinate, not succinic acid, is found. PETases can't catalyze the hydrolysis of aliphatic polyesters like polybutylene succinate or polylactic acid. Specifically, succinate, isocitrate and citrate stimulate flavinylation of the SDHA.