It is a toxicant and carcinogen in animals. Apoptosis in germ cells can be induced by variety of naturally occurring toxicant. It is a suspected respiratory toxicant, immunotoxicant, gastrointestinal toxicant and neurotoxicant. Chlorine is the most commonly manufactured oxidizing toxicant. DES is an important developmental toxicant which links the fetal basis of adult disease. In chronic exposures, organisms come into contact with low, continuous doses of a toxicant. It is also a suspected reproductive toxicant, and may also be a skin/sense organ toxicant. Lead is a toxicant that can cause serious and irreversible health damage. Furthermore, it concluded that it is not a developmental toxicant. BBP was listed as a developmental toxicant under California's Proposition 65 on December 2, 2005. Research has shown it to be a testicular toxicant in rats and dogs. It is a bioaccumulative environmental toxicant. Anything falling outside of the definition cannot be classified as that type of toxicant.