Pathogenic bacteria also cause infections such as tetanus, typhoid fever, diphtheria, syphilis, and leprosy. Meningitis is the most common neurological presentation in early syphilis. This includes acne, cholera, brucellosis, plague, malaria, and syphilis. It had been prescribed to Pickford to topically treat sores caused by his chronic syphilis. Late congenital syphilis is a subset of cases of congenital syphilis. He also proposed new treatments for diseases such as syphilis. People with tertiary syphilis are not infectious. The most common form of ocular syphilis is uveitis. This is a subset of cases of congenital syphilis. The study was designed to measure the progression of untreated syphilis. Capone began in Chicago as a bouncer in a brothel, where he contracted syphilis. For this reason, the study emphasized observation of individuals with late latent syphilis. The parenchymal syphilis, presents as tabes dorsalis and general paresis. Mercury was used in the treatment of syphilis. It was also used once for treatment of syphilis.