Dengue fever is a mosquito-borne tropical disease caused by the dengue virus. Dengue vaccine is a vaccine used to prevent dengue fever in humans. In contrast to dengue fever, Chikungunya fever very rarely causes hemorrhagic complications. Climate heavily affects mosquito vectors of malaria and dengue. These include diseases such as dengue, malaria, cholera, and colds. Some viruses such as HIV, dengue, and chikungunya do not have vaccines available. Sabin also developed vaccines against other viral diseases, including encephalitis and dengue. East Timor is a poor country, with health issues including malaria and dengue fever. Zika virus is a mosquito-borne flavivirus closely related to the dengue and yellow fever viruses. Zika fever also has similar symptoms as dengue. The diagnosis of dengue fever may be confirmed by microbiological laboratory testing. The symptoms can be mistaken for those of dengue fever and Zika fever. There are four different types of viruses in dengue fever. ARTICHOKE researched the potential of dengue fever and other diseases. These included helminthiasis, schistosomiasis, dengue, and lymphatic filariasis.