Circular wavefront profiles associated with aberrations may be mathematically modeled using Zernike polynomials. Mycoplasmae may induce cellular changes, including chromosome aberrations, changes in metabolism and cell growth. He concluded that light could not be refracted through a lens without causing chromatic aberrations. These cytokine variations allude to immune response aberrations resulting in autoimmunity. Lenses suffer from aberrations that distort images. Optical systems, and in particular optical aberrations are not always rotationally symmetric. The fluorite also serves to correct optical aberrations in these lenses. Zernike polynomials correspond to the normal lens aberrations. It includes the effects of diffraction, aberrations and pixelation. Simple lenses are subject to the optical aberrations discussed above. Age acceleration is highly related to various genomic aberrations in cancer tissues. In addition there were allegations of financial irregularity and of doctrinal aberrations. This was likely Newton's choice of a way to reduce chromatic aberrations. There is a correlation between pupil size and aberrations. The cooke triplet is noted for being able to correct the Seidel aberrations.