If used concomitantly with warfarin, celecoxib may result in increased risk of bleeding complications. Increase of ectopic pacemaker activity can occur when pseudoephedrine is used concomitantly with digitalis. The concentrations of these drugs may increase if they are used concomitantly with omeprazole. Therefore, norfloxacin should be used with caution in individuals receiving NSAIDS concomitantly. If chlorprothixene is given concomitantly with opioids, the opioid dose should be reduced (by approx. Dexamethasone does not cross-react with the assay and can be administered concomitantly during testing. Where an immediate effect is required, heparin must be given concomitantly. Pain relief is administered concomitantly to the treatment of the primary disease causing tenesmus. If used concomitantly with lithium, celecoxib increases lithium plasma levels. Chlorprothixene may increase the plasma-level of concomitantly given lithium. Using another antibiotic concomitantly with carbapenem can help prevent the development of carbapenem resistance. Several factors concomitantly affect microbial growth and activity. Tooth loss can occur secondary or concomitantly to many diseases. Calcimimetics can be used concomitantly with vitamin D therapy. Concomitantly, one molecule of FADH, NADH and acetyl CoA are formed.