Heat denatures the proteolytic enzyme and prevents autolysis. Autolysis and putrefaction also play major roles in the disintegration of cells and tissues. Autolysis is initiated by the cells' lysosomes releasing digestive enzymes into the cytoplasm. The last function of a lysosome is to digest the cell itself through autolysis. This decomposition process, known as autolysis, occurs when the cells produce digestive enzymes and self-destruct. On the other hand, Autolysis is apoptosis of a cell by its own enzymes. In beer brewing, autolysis causes undesired off-flavors. The conditions leading to the autolysis of this bacterium are not well known. This process is known as autolysis. As the wine ages further, more complex notes may develop from the effects of autolysis. They called this autolysis after Christian de Duve and Alex B. Novikoff. If not properly managed, wine faults can potentially develop from autolysis.