Acral lentiginous melanoma is a kind of lentiginous skin melanoma. The pathogenesis of acral lentiginous melanoma remains unknown at this time. Other histological signs of acral lentiginous melanoma include dermal invasion and desmoplasia. Bob Marley died from a lentiginous skin melanoma on May 11, 1981. The word lentiginous comes from the latin for freckle.