There are variety of less significant changes. Some of the most significant changes are described below. Some less significant and invisible changes were made. It is regarded as one of the most significant in jazz history. However, aphthae are capable of causing significant discomfort. Some of the most significant are listed below. Sheldrake interpreted the result as highly significant statistically. The first and smallest occurred at the time of less significant interaction. StartTLS is one of the most significant extensions. Among his most significant students were A. Famines resulting in significant mortality are frequent. The most significant of these adaptations are 1. Some of her most significant aid came from women. Hyperthyroidism may be asymptomatic or present with significant symptoms. It is not recommended in those with significant liver disease.