Vitelliform lesions are often present and some cases involve cystoid macular edema. Reported adverse reactions include intraocular inflammation, bleeding, and cystoid macular edema (swelling of the retina). Other causes for floaters include cystoid macular edema and asteroid hyalosis. In late cases cystoid macular edema sometimes develops which can further lead to macular destruction. Other unusual presentations described include cystoid macular edema, temporal arteritis, and cluster headaches.