There are prokaryotic homologs of all the key molecules of eukaryotic mitosis (e.g., actins, tubulins). Ta0583 is even more similar to the eukaryotic actins. This is one of the two nonmuscle cytoskeletal actins. It has the highest sequence similarity to eukaryotic actins of any known actin homologue. The alpha actins, found in muscle tissues, are a major constituent of the contractile apparatus. Like the other bacterial actins, FtsA binds ATP and can form actin-like filaments. Alpha actins are a major constituent of the contractile apparatus. Actins have a variety of roles in synaptic functioning. Actins are a family of globular multi-functional proteins that form microfilaments. Actins are highly conserved proteins that are involved in cell motility, structure and integrity.