There have been a number of poisonings associated with realgar ingestion. Tintoretto also used the rare arsenic sulfide pigments realgar and orpiment. So the emperor supplied him with gold, cinnabar, copper sulphate, realgar, and so forth. Arsenic, as realgar () and orpiment (), was known in ancient times. Acanthite, auripigment, galena, realgar and sphalerite are among the ores found at Choquelimpie. The content of the ore consists of red orpiment, realgar, antimony and arsenopyrite. Pyrite, stibnite, orpiment and realgar are the main minerals forming the ore. After a thousand years it changes into realgar. It forms gradually from realgar under exposure to light. Orpiment is found in volcanic environments, often together with other arsenic sulfides, mainly realgar. Other sulfide minerals occurring with these deposits include pyrite, arsenopyrite and realgar. As stated above, pararealgar is an alteration product of realgar resulting from exposure to light. The Five Minerals are realgar, cinnabar, orpiment, alum, and laminar malachite []. Arsenic sulfides (orpiment, realgar) and oxides have been known and used since ancient times. Realgar was commonly applied in leather manufacturing to remove the hair from animal pelts.