The primary symptom is cough with sputum that may be purulent. Microfilariae have been recovered from spinal fluids, urine and sputum. An acute exacerbation presents with increased shortness of breath and sputum production. Symptoms may include chest pain and a prolonged cough producing sputum. Symptoms include fever, cough, and blood-tinged sputum. The main symptoms include shortness of breath and cough with sputum production. Other reported nonspecific symptoms include cough, rhinorrhea, sputum, vomiting, headache, and seizure. Reduction in viscosity of cystic fibrosis sputum in vitro by gelsolin. Diagnosis of BCC involves culturing the bacteria from clinical specimens, such as sputum or blood. People with only pneumonia may have a prominent cough with sputum and shortness of breath. Pneumonia caused by "Streptococcus pneumoniae" is associated with rusty colored sputum. The egg is found in the faeces, sputum, or urine of the definitive host. Diagnosis is by a urinary antigen test and sputum culture. Diagnosis is by testing the blood, sputum, or fluid from a lymph node. Neutrophils are also observed in large numbers in sputum from patients with COPD.