There have also been reports of using topical tacrolimus ointment. Paronychia is often treated with antibiotics, either topical or oral or both. Pseudoephedrine can be used either as oral or as topical decongestant. The associated itching may be treated with topical or systemic antihistamines. The possible neuroprotective effects of various topical and systemic medications are also being investigated. There are various forms of topical retinoids. Treatment involves discontinuing the use of topical steroids. Cyclobenzaprine is also used by compounding pharmacies in topical creams. However, there are certain general causes for concern with topical administration of antibiotics. They are liquids used primarily as a topical antiseptic. There is limited evidence for the efficacy of topical and systemic therapies for mycosis fungoides. Patients are first treated with sunscreen and topical steroids. It is comparable in effectiveness to prescription topical antiviral agents. There are several NSAIDs available for topical use, including diclofenac. Steroid-induced rosacea is caused by the use of topical steroids.