Manifestations of decompensation in cirrhosis include gastrointestinal bleeding, hepatic encephalopathy (HE), jaundice or ascites. Some side effects include intracranial hemorrhage, hepatitis, hepatic decompensation, hyperglycemia and diabetes mellitus. Post-market surveillance reports show hepatic decompensation and hepatic failure associated with Viekira Pak use. Symptoms may be acute or chronic with intermittent decompensation. Such decompensation unmasks the underlying disease, worsening its symptoms. A jugular venous distension is the most sensitive clinical sign for acute decompensation. This may lead to acute metabolic decompensation and sudden death. This leads rapidly to dehydration and electrolyte imbalance and metabolic decompensation. With subsequent decompensation, testosterone was stable, but cortisol and SHBG decreased. Decompensation may occur due to fatigue, stress, illness, or old age. Given these combinations of conditions, decompensation from schizotypy to schizophrenia would result. Decompensation describes an inability to compensate for these deficiencies. In that case, they should be observed for signs of decompensation indicating a serious injury.