Benign osteoblastoma is virtually indistinguishable from osteoid osteoma. Osteomalacia is associated with increase in osteoid maturation time. Curettage is also a major method used for removing osteoid osteoma and osteoblastoma. Tumor cells are included in the osteoid matrix. Microscopically&colon; The characteristic feature of osteosarcoma is presence of osteoid (bone formation) within the tumor. The predominant fiber-type is type I collagen and comprises ninety percent of the osteoid. The products of the cell are mostly for transport into the osteoid, the non-mineralized matrix. At this stage they are not yet mineralised, and are called "osteoid". Some of the osteoblasts become incorporated within the osteoid to become osteocytes. Osteonectin is also detectable in osteoid, bone matrix proper, and dentin. Abnormalities of chromosome 13 have been observed in canine osteoid chondrosarcoma and lymphosarcoma. It is similar to osteoid in bone and is thickest when dentinogenesis is occurring. Before the organic matrix is mineralized, it is called the osteoid. Then the osteoblasts create an extracellular matrix containing Type-I collagen fibrils, which is osteoid. Osteoblastoma is an uncommon osteoid tissue-forming primary neoplasm of the bone.