Usage of such words hinders intelligibility between dialects and is greatly discouraged in formal situations. To the extent that formality hinders reader comprehension, it is less desirable. This hinders gene flow between populations and ultimately leads to gene isolation. The lack of reading skills hinders adults from reaching their full potential. This changes the charge or sterically hinders the antibiotic, decreasing its ribosomal binding affinity. This hinders research which could improve diver safety. Sloth hinders man in his righteous undertakings and becomes a path to ruin. Furthermore, the social acceptance of many these problems hinders their eradication. The terrain is mountainous and hilly with poor transportation routes that hinders harvesting. Still, a paucity of credit options hinders the overall economy. This hinders the scalability of this approach and creates problems with large datasets. This further hinders chances for regeneration and reinnervation. Moreover, it logically hinders the development of non-bespoke hypnotherapy protocol. According to Open Doors, to many Bhutanese this hinders the ability of Christians to proselytize. Sleep deprivation also hinders the healing of burns on rats.