They modulate bile secretion, exocrine pancreas secretion, and satiety. Pearson syndrome is a mitochondrial disease characterized by sideroblastic anemia and exocrine pancreas dysfunction. In pancreatitis, enzymes of the exocrine pancreas damage the structure and tissue of the pancreas. The pancreas has both an endocrine and a digestive exocrine function. The main glands are all exocrine glands, secreting via ducts. This causes atrophy of the exocrine glands and progressive fibrosis. Other cells will give rise to the exocrine and ductal pancreatic cell populations. It is both an endocrine gland and an exocrine gland. There are several types of pancreatic cancer, involving both the endocrine and exocrine tissue. Cats with exocrine pancreatic insufficiency, moreso than dogs, may have low serum folate. The genes often found mutated in PanNETs are different from those in exocrine pancreatic cancer. The pancreas consists of two parts, an exocrine and an endocrine component. Treatment of chronic pancreatitis typically includes pain control and management of exocrine insufficiency. Dry mouth can occur; other exocrine glands are affected only rarely. In fact, they more closely resemble exocrine than endocrine tumors.