The study of the energetics between different conformations is referred to as conformational analysis. The switch regions are loops of alpha-helices with conformations sensitive to guanine nucleotides. Prions are proteins of particular amino acid sequences in particular conformations. However, there are two possible gauche conformations and only one anti conformation. Both actin and tubulin bind to CCT in open conformations in the absence of ATP. Lysozyme exhibits two conformations&colon; an open active state and a closed inactive state. In cyclohexane, the two chair conformations have the same energy. This receptor can exist in three conformations. Creating these files requires determining which of the various theoretically possible protein conformations actually exist. DNA topology is the tertiary conformations of DNA, such as supercoiling, knotting, and catenation. With a calixarene guest different chemical conformations (cone, 1,2-alternate, 1,3-alternate) are in rapid equilibrium. Antigen specificity is due primarily to the side-chain conformations of the antigen. Mad2 is capable of forming multimers and adopts at least two structural conformations. For example, ethane (CH) has three equivalent staggered conformations. At room temperature the two chair conformations rapidly equilibrate.