Favourable disease stage correlates with a higher risk for development of neurologic sequelae. Peripheral neuropathy including paralysis is noticed as late sequelae after recovery from acute intoxication. Bacteremia and endocarditis are uncommon but serious sequelae. They are benign and do not cause any neurological sequelae. However, the risks of neurodevelopmental sequelae may outweigh the benefits. It results either from disease (conjunctival sequelae of trachoma) or trauma. Instead, management focuses on treating the sequelae should the patient become symptomatic. Secondary prevention is preventing further sequelae of already established disease. Long-term follow-ups showed similar results, with 16% having permanent neurological sequelae. DSM-5 can be utilized to diagnose TBI and its psychiatric sequelae. The hemodynamic sequelae of AI are dependent on the rate of onset of AI. Several consequent reports from China on some recovered SARS patients showed severe long-time sequelae. Some conditions may be diagnosed retrospectively from their sequelae. A number of long term sequelae can occur after frostbite. Concerns have been raised about long-term sequelae of the disease.