Urination is controlled by the pontine micturition center in the brainstem. The pain is characteristically intense during/after defecation or micturition (espec. Urine, excreted by the kidneys, collects in the bladder before disposal by urination (micturition). Analysis of urine flow may aid in establishing the type of micturition (urination) abnormality. The micturition reflex normally produces a series of contractions of the urinary bladder. When activated, the PMC relaxes the urethral sphincter allowing for micturition to occur. This results in loss of detrusor contraction, difficulty in initiating micturition and overflow incontinence. It enhances bladder storage via suppression of the afferent limb of the micturition reflex pathway. Physiologically, micturition involves coordination between the central, autonomic, and somatic nervous systems. There is no specific treatment for micturition syncope. The muscles controlling micturition are controlled by the autonomic and somatic nervous systems. The spikes correspond to the bladder contractions associated with the micturition reflex. Serotonin plays a key role in mechanisms involved in micturition and continence. It forces urine into and through the urethra in order for micturition. Boyer specialized in urological pathology, especially disorders of micturition.