Pegylated interferon and ribavirin are useful in reducing viral load. Naltrexone is effective in suppressing the cytokine-mediated adverse neuropsychiatric effects of interferon alpha therapy. These include receptors for erythropoietin, thrombopoietin, most interleukins and interferon. Macrophages can be stimulated by T cell secretion of interferon gamma. The vaccine resulted in specific interferon gamma cell production. NSs is hostile and combative against the hosts interferon (IFNs) antiviral response. They showed that human beta interferon was an unusually hydrophobic glycoprotein. Targets for degradation include several IRF transcription factors required for interferon gene transcription. He was treated with human interferon and convalescent serum. He was treated with interferon but developed liver cancer. I interferon signaling through different molecular mechanisms. The dose and length of treatment with interferon were established. I and type III interferon signaling pathways. I interferon in host immunity mediated by STING. The purification of human beta interferon did not occur until 1977.