Cardiac ischemia may be asymptomatic or may cause chest pain, known as angina pectoris. This can help ameliorate symptoms of ischaemic heart disease such as angina pectoris. Obesity is associated with cardiovascular diseases including angina and myocardial infarction. His doctors attributed the pain to angina pectoris. Isosorbide mononitrate is a nitrate-class drug used for the prevention of angina pectoris. This has led to their use in treating high blood pressure and angina pectoris. Types include stable angina, unstable angina, myocardial infarction, and sudden cardiac death. The approved uses are for the long-term treatment of hypertension and angina pectoris. It became popular in Europe as a treatment for angina pectoris. His alcoholism resulted in cardiomyopathy, coronary artery disease, angina, dyspnea, and syncopal spells. He is credited with advancing the understanding of angina pectoris. Brief ischemia is associated with intense chest pain, known as angina. Severe narrowings may cause chest pain (angina) or breathlessness during exercise or even at rest. Complications such as cavernous sinus thrombosis and Ludwig angina can be life-threatening. Case reports have linked bitter orange supplements to strokes, angina, and ischemic colitis.