It contains vitamin B1, B2, B6, folic acid, dietary fiber, oligosaccharide, cysteine, arginine and glutamine. These core histones are rich in lysine and arginine residues. The most prevalent protein methylations produce specific histones from arginine and lysine. Clavulanic acid is biosynthesized from the amino acid arginine and the sugar glyceraldehyde 3-phosphate. The histone methyltransferases are specific to either lysine or arginine. The pathways linking arginine, glutamine, and proline are bidirectional. Agmatine is a chemical substance which is naturally created from the amino acid arginine. Arsenic has been shown to be helpful in metabolizing the amino acid arginine. This enzyme participates in arginine and proline metabolism. A pair of arginine and asparagine residues on C2 stabilizes the transition state. A glutamate on a nearby loop interacts with nitrogens on the target arginine residue. Replacement of any of the arginine leads to slow down or failure of secretion. Additionally, methylamine is produced during PADI4-dependent arginine demethylation. Krebs started working on the possible method for the synthesis of arginine.