Complete clearance has been demonstrated in up to 45% of patients with actinic keratoses. Furthermore, shiny palmar keratoses with central dells are also present. No treatment of seborrheic keratoses is necessary, except for aesthetic reasons. Actinic keratoses are pre-malignant growths. PDT is used to treat actinic keratoses, acne, photoaging and skin cancer. Seborrheic keratoses are not pre-malignant. When correctly performed, removal of seborrheic keratoses will not cause much visible scarring. Clinically, epidermal nevi are similar to seborrheic keratoses in appearance. Punctate depigmentation appears in raindrop shapes, and hard keratoses are either localized or diffuse. Like liver spots, seborrheic keratoses are seen more often as people age. Condylomas and warts can clinically resemble seborrheic keratoses, and dermatoscopy can be helpful. From a histological perspective, DPN resembles seborrheic keratoses.