Therefore, GSH depletion exacerbates cell damage due to free radical generation. Alcohol also tends to cause dehydration and exacerbates AMS. This exacerbates the problem and increases the downward pressure on the stock, increasing dilution. Liver disease exacerbates its sedative effects. However, fluid overload can exacerbates acute kidney injury. This can often concentrate water in a ways that exacerbates erosion instead of reducing it. The link to sexual immorality further exacerbates this stigma. Increased skin permeability under irradiation exacerbates this possibility. For example, the inaccessibility of clean water exacerbates poor sanitation conditions. In this way, deforestation exacerbates climate change. However, inhibition of VTA- projections exacerbates social withdrawal. Spherical aberration exacerbates myopia in low light (night myopia). Climate change probably exacerbates the problem. Climate change exacerbates the situation with typhoons in the Philippines. However, an increase in negative emotions (i.e. anger) only exacerbates the initial conflict.