The 1539 alliance between Francis and Charles had soured, eventually degenerating into renewed war. There were a couple of incidents that soured relations after that. The generally positive reaction quickly soured despite royal patronage. Over time their relations soured, due in part to their strong personalities. Local relations with the oil industry gradually soured through the period. The leak apparently soured relations between the two. If anything, the violence soured relations. That year, relations with Israel soured. But in reality, after this appointment, relations between the two countries soured. The incident further soured relations between Mulder and Matheson. Relations between Dimitri and Putiatin also soon soured. Buttermilk is a common modern substitute for naturally soured milk. During the Ifat Sultanate, Muslim relations with the Solomonic dynasty soured. Upset bankers, who had soured over the power struggle, left the company. However, their relationship quickly soured due to Hornsby's overbearing personality.