Nonprescription oral diphenhydramine (U.S. trade name Benadryl) is the most commonly suggested antihistamine. Diphenhydramine and doxylamine are widely used in nonprescription sleep aids. Because of its sedative properties, diphenhydramine is widely used in nonprescription sleep aids for insomnia. A number of nonprescription medications have shown to be effective in promoting sleep. Bayer would attain second place globally in nonprescription drugs. In 1998, a 5% formulation of minoxidil was approved for nonprescription sale by the FDA. It changed its name to the Nonprescription Drug Manufacturers Association in 1989. Mineral oil is the only nonprescription lubricant.