Some sources also include "Mycobacterium avium" subspecies "paratuberculosis" (MAP). It is caused by the bacterium "Mycobacterium avium" subspecies "paratuberculosis". In cattle, the main signs of paratuberculosis are diarrhea and wasting. However, cross-reaction between "M. avium avium, M. tuberculosis," or "M. avium paratuberculosis" is a disadvantage. In deer, paratuberculosis can progress rapidly. Johne's disease, a paratuberculosis disease of cattle he described in 1895, is named for him. Mycobacterium avium" subspecies "paratuberculosis (MAP) is an obligate pathogenic bacterium in the genus "Mycobacterium". Paratuberculosis is a reportable disease in some states of the US. In many individuals, genetic factors predispose individuals to "Mycobacterium avium" subsp." paratuberculosis" infection. Once the symptoms appear, paratuberculosis is progressive and affected animals eventually die.