Paracrine signalling mediates the response to epidermal growth factor receptor kinase inhibitors. Filaggrin binds to keratin fibers in epidermal cells. This inner layer is a germinal epithelium that gives rise to all epidermal cells. The biopsy should include the epidermal, dermal, and subcutaneous layers of the skin. This venom is produced by glandular cells in the epidermal tissue covering the spines. There are two different kinds of melasma, epidermal and dermal. Those stem cells and their differentiated progeny are organized into columns named epidermal proliferation units. The epidermal receptors are tactile in function. HER2 is a member of the human epidermal growth factor receptor (HER/EGFR/ERBB) family. The adaxial sclerenchyma tissue sometimes forms strands that are opposite or extend to epidermal veins. For example, scratching is induced by pruritogens that stimulate nociceptors on epidermal tissues. Most of the epidermal cells are relatively flat. Creases in the epidermal tissue connect the scales of rattlesnakes. It normally lives on the outer surface of the starfish feeding on sloughed-off epidermal tissue. Filaggrin is essential for the regulation of epidermal homeostasis.