The urethral folds form the labia minora and the labioscrotal swellings form the labia majora. Bilateral to the urethral fold, genital swellings (tubercles) become prominent. These structures are the future scrotal swellings and labia majora in males and females, respectively. Camphor was used in ancient Sumatra to treat sprains, swellings, and inflammation. He had multiple bruises, swellings and abrasions on his face and head. The disease can cause red itchy swellings below the skin called "Calabar swellings". These areas are formed as swellings known as the three primary brain vesicles. The dermatitis shows itself in painful and long continued swellings and eruptions. These lingual swellings quickly expand and cover the median tongue bud. Female Bili apes have genital swellings similar to other chimpanzees. Early in the fifth week the cells form two swellings called the cloacal folds. Mandibular trismus is a rare finding but may be present with larger swellings. The spatulate swellings were later frequently made in a quatrefoil design. The frontal part of the oesophageal nerve ring is large, connecting two lateral swellings. The nasal crest side is very rugose with a series of bosses and swellings.