These include aminoglycosides such as streptomycin and gentamicin, tetracyclines (especially doxycycline), and the fluoroquinolone ciprofloxacin. These include clindamycin, anisomycin, cycloheximide, chloramphenicol, tetracycline, streptomycin, erythromycin, and puromycin. The antibiotics often used are streptomycin, chloramphenicol and tetracycline. Several antibiotics are effective for treatment, including streptomycin, gentamicin, and doxycycline. If infection occurs or is suspected, treatment is generally with the antibiotics streptomycin or gentamicin. However, "E. coli" are extremely sensitive to such antibiotics as streptomycin or gentamicin. For active tuberculosis, it is often used with rifampicin, isoniazid, and either streptomycin or ethambutol. Gentamicin may be easier to obtain than streptomycin. Some strains of "S. flexneri" have resistance to the antibiotics streptomycin, ampicillin, or trimethoprim. Treatment is done by using antibiotics such as erythromycin, dihydrostreptomycin, streptomycin, sulfonamides, tylosin, and fluoroquinolones. A combination of penicillin and streptomycin therapy was used in the past. It developed high-vacuum processes to produce penicillin, blood plasma, and streptomycin for US military use. Treatment is typically with the antibiotic streptomycin. The now uncommonly used streptomycin takes its name directly from "Streptomyces". Congenital deafness has been reported in children whose mothers received streptomycin during pregnancy.