For example, triphenyl phosphate is the ester derived from phosphoric acid and phenol. Catechol is produced industrially by the hydroxylation of phenol using hydrogen peroxide. The lotion is produced with additional ingredients such as phenol and calcium hydroxide. Baekeland began to investigate the reactions of phenol and formaldehyde. This diagram shows an o-alkylation between phenol and methanol. It is also soluble in strongly alkaline aqueous solutions due to deprotonation of the phenol. It was filled with carbolic acid (or phenol). In 1909, Leo Hendrik Baekeland invented bakelite made from phenol and formaldehyde. Most of the worldwide production of phenol and acetone is now based on this method. Salicylic acid (SA) is a hormone with a related structure to phenol. The rest is produced synthetically, by methylation of phenol or hydrolysis of chlorotoluenes. "Cryptanaerobacter phenolicus" is a bacterium species that produces benzoate from phenol via 4-hydroxybenzoate. The immediate product with phenol itself is 4-hydroxymandelic acid. The reactive species is the phenoxide anion (CHO) formed by deprotonation of phenol. Damp spots were removed by means of disinfectants like quinine or phenol.