Antihistamines and decongestants may provide allergy relief. Medications that cause vasoconstriction include&colon; antihistamines, decongestants, and stimulants. Medications that decrease saliva production include antihistamines and antidepressants. It is unclear if nasal irrigation, antihistamines, or decongestants work in children with acute sinusitis. Capsaicin-induced asthma might be treated with oral antihistamines or corticosteroids. Treatment is typically with antihistamines such as diphenhydramine and ranitidine. Prophylactic antihistamines or corticosteroids may be used concomitant with the antitoxin. Medications such as antihistamines and diuretics can be predisposing factors. Moreover, it is recommended against using antihistamines and decongestants in children with OME. Medications, such as antihistamines and antidepressants, can also impair salivary flow. Treatment usually involves adrenaline (epinephrine), antihistamines, and corticosteroids. It does not respond to antihistamines, corticosteroids, or epinephrine. Corticosteroids, antihistamines, and analgesics are the main line of treatment. Individuals with chronic hives may need other medications in addition to antihistamines to control symptoms. The degree of benefit is similar to other antihistamines such as diphenhydramine.