Age is the best predictor of disease progression. Treatment focuses on improving the symptoms and preventing the progression of the disease. The drug targets the role of macrophages in disease progression. Targeting galectin-3 might be effective in slowing prostate cancer progression. Little is known about factors affecting cirrhosis risk and progression. Medical therapy of PBC targets disease progression and symptom control. Nevertheless, the relationship between disease progression and disability is not linear. However, transcriptional silencing may be of more importance than mutation in causing progression to cancer. A few studies have worked on providing details related to the outlook of disease progression. Too much inhibition leads to unregulated cell cycle progression and tumorigenesis. This adds an oscillation to the apparent progression of the lunar phases. Bradykinins have been implicated in a number of cancer progression processes. Evidence on relative effectiveness in reducing disability progression is unclear. The effect of statins on the progression of AS is unclear. The defining chord progression is then established.