Immunosuppressive drugs help manage organ transplantation and autoimmune disease. Birds are susceptible to tumours, immune deficiency and autoimmune diseases. Certain individuals are genetically susceptible to developing autoimmune diseases. Genetic factors may create a predisposition towards developing these autoimmune diseases. Managing inflammation is critical in autoimmune diseases. Many people with autoimmune hepatitis have other autoimmune diseases. These diseases tend to have characteristic pathological effects which characterize them as an autoimmune disease. Cyclophosphamide is used to treat cancers and autoimmune diseases. Neuromuscular junction diseases can be of genetic and autoimmune origin. Autoantibodies to titin are produced in patients with the autoimmune disease scleroderma. The Y chromosome has no identified mutations associated with autoimmune disease. They have also been implicated in autoimmune and inflammatory disorders. Findings implicate neuroinflammation in the etiology of fatigue in autoimmune and related disorders. Some progression to autoimmune disease has been observed. Health tests are available for both eye diseases and autoimmune thyroiditis.