Additionally, the epithelium has lymphoid stroma with germinal center formation. Testicular seminoma originates in the germinal epithelium of the seminiferous tubules. T-cells can be stimulated by similar, germinal centre dendritic cells. There are two types of cells in the germinal epithelium. Both develop in the ovarian follicle from a population of cells that surrounds germinal cells. "Small non-cleaved cells" are compared to "large non-cleaved cells" of normal germinal center lymphocytes. Fresh eggs may be developing from the germinal epithelium throughout life. Implantation marks the end of the germinal stage of embryogenesis. It is exclusively present in the B-cells of both healthy and neoplastic germinal centres. B cells are activated and proliferate in areas called germinal centers in the tonsil. Antenatal corticosteroids have a role in reducing incidence of germinal matrix hemorrhage in premature infants. This serves as a germinal centre survival signal for autoreactive B-cells. CMV has a high affinity for the developing germinal matrix of the brain. When activated, these may develop into what is called a germinal centre. All were executed on 4 Germinal (24 March).