An intussusception has two main differential diagnoses&colon; acute gastroenteritis and rectal prolapse. Bowel intussusception can occur with various benign colonic tumors. Intestinal pseudo-obstruction, ileus, intussusception, hypoganglionosis, and encopresis in children have been associated with porphyrias. However, internal intussusception rarely progresses to external rectal prolapse. Older recommendations were to avoid rotavirus vaccination in babies who have had intussusception. Rectopexy has been shown to improve anal incontinence (fecal leakage) in patients with rectal intussusception. Some of the reported manifestations include intussusception, small intestinal bacterial contamination, colitis, and others. For rectal internal intussusception treatment is surgical, either STARR or rectopexy. In the most frequent type of intussusception, the ileum enters the cecum. There can be difficulty differentiating between internal intussusception and a normal rectal fold. Rectal intussusception by contrast is not life-threatening. Enteroceles are coexistent in 11% of patients with internal intussusception. In babies, hematochezia in conjunction with abdominal pain is associated with intussusception. Relapse of the intussusception after treatment is a problem. Fever is not a symptom of intussusception.