This motif position and structure are evolutionarily conserved. Ferritin genes are highly conserved between species. These proteins are highly conserved across species. Ku is evolutionarily conserved from bacteria to humans. Serotonin is evolutionarily conserved and appears across the animal kingdom. BMP4 has seven residues which are conserved and glycosylated. Heme oxygenase is conserved across phylogenetic kingdoms. The LPL gene is highly conserved across vertebrates. However, most promoter sequences were conserved between mouse and rat. This is similar to the concept of interspecies constraint in conserved sequences. The termini in contrast are not conserved between species. This is conserved between mammals and yeast. Neighboring regions however are generally not conserved. Rad51 is highly conserved from yeast to humans. The process is highly conserved across biology.