Whole genome sequencing has established the mutation frequency for whole human genomes. Comparative genomic studies allow for comparison of eukaryotic genomes. At 1.3 Gb, its genome is one of the largest known pathogen genomes. Following are the six earliest sequenced genomes of protists. Following are the five earliest sequenced genomes of fungi. Following are the five earliest sequenced genomes of plants. They also have the smallest eukaryotic genomes. The entire genomes of 25 melanomas were sequenced. Following are the five earliest sequenced genomes of animals. Analysis of CRISPR sequences revealed coevolution of host and viral genomes. Microsporidia have the smallest known (nuclear) eukaryotic genomes. This is consistent with the higher complexity of the genomes of eukaryotes compared to prokaryotes. Bidirectional promoters are a common feature of mammalian genomes. Palindromic motifs are found in most genomes or sets of genetic instructions. Set of genes not present in all but one or some genomes under study.