His dissertation was on commercial synthesis of vitamin B6. The Norwegian version has reduced levels of vitamin B6. Intertrigo is also a known symptom of vitamin B6 deficiency. This disturbance was temporarily corrected by large doses of vitamin B6. A good example is provided with pyridoxal phosphate, a form of vitamin B6. Cases of secondary cystathioninuria are not responsive to vitamin B6 administration. Past cases of hydrazine exposure have documented success with Pyridoxine (Vitamin B6) treatment. Riboflavin, pantothenic acid, biotin, niacin, and vitamin B6 are unaffected. Tentative evidence supports vitamin B6 and chasteberry. Isoniazid is associated with pyridoxine (vitamin B6) deficiency because of its similar structure. However, the cystathionase has an altered ability to bind to vitamin B6, its coenzyme. Vitamin B6 or correcting iron deficiency may also be useful. Pyridoxine or vitamin B6, it becomes a major compound in the metabolism of amino acids. It also contains appreciable amounts of vitamin B6, vitamin C, and manganese (18-25% DV). These conversions require vitamin B6, vitamin C, and S-adenosylmethionine.