The practice of doctors prescribing placebos that are disguised as real medication is controversial. Those drugs considered less suitable for prescribing are clearly identified. Many prescribers lack the digitized information systems that reduce prescribing errors. Drug metabolism is assessed in pharmacokinetics and is important in drug research and prescribing. Pharmacists should keep records of sales with the prescribing doctor and the patient's details. There was also concern about the large increase in prescribing psychiatric drugs for children. Free samples have been shown to affect physician prescribing behavior. It includes key information on the composition, description, selection, prescribing, dispensing and administration of medicines. Opioid prescribing in English general practice mirrors general geographical health inequalities. An FDA Alert warned against prescribing pemoline for ADHD. Patients and clinicians will have access to the prescribing records. Such reactions occur usually only at the higher dose end of the prescribing spectrum. The socioeconomic costs of the continued widespread prescribing of benzodiazepines is high. This allows for prescribing and referral, insurance reimbursement, and admitting privileges to health care facilities. This has been associated with an increased risk of inappropriate prescribing.