Doses 98% less than common dosing had the same effect. Correct dosing of medications in children is dependent on weight. Patients with renal abnormalities must exercise caution when dosing hydromorphone. One common cause of antibiotic resistance is due to incorrect dosing. Furthermore, complications may arise from low blood sugar caused by excessive dosing of insulin. For patients on insulin, patient involvement is important in achieving effective dosing and timing. Anti-tumor activity and toxicity can be controlled by adjusting the administered adaptor molecule dosing. Opioid-tolerant patients may require higher than normal dosing. I request that you not use a [8-hourly] dosing regimen. Additionally, dosing naltrexone after recent opioid use could lead to precipitated withdrawal. This is especially true with bolus dosing (Canadian term). The American College of Chest Physicians publishes clinical guidelines on heparin dosing. Subcutaneous injections have better evidence than under the tongue dosing. This reduces scattering and the degree of late toxicity following dosing. Adverse events are generally caused by incorrect dosing.