Benzodiazepines bind to GABA receptors and work as muscle relaxants. Generalized dystonia has also been treated with such muscle relaxants as the benzodiazepines. Common treatments include heat, rest, paracetamol, NSAIDs and muscle relaxants. Secretions from dendrobatids are also showing promise as muscle relaxants, heart stimulants and appetite suppressants. Many of these relaxants and anticonvulsants have some success but also have unwanted side effects. Evidence supporting the use of opioids and muscle relaxants is poor. Baclofen and other muscle relaxants are being studied for potential use for persistent hiccups. Muscle relaxants may be used to control spasms. Evidence is poor for SSRIs, propranolol and muscle relaxants. Muscle relaxants do not render patients unconscious or relieve pain. Currently, treatment usually involves symptomatic therapy with pain medication, muscle relaxants, and antivenom. The most commonly prescribed drugs for low back pain included skeletal muscle relaxants. Though evidence for pain medication and muscle relaxants is lacking. These were drugs that worked chiefly as anti-anxiety agents and muscle relaxants. Patients most commonly report sedation as the main adverse effect of muscle relaxants.