The role of the nebulised recombinant human deoxyribonuclease (rhDNase) remains inconclusive. Deoxyribonuclease IV is a type of deoxyribonuclease that functions at AP-sites. Deoxyribonuclease gamma is an enzyme that in humans is encoded by the "DNASE1L3" gene. Deoxyribonuclease I (usually called DNase I), is an endonuclease coded by the human gene DNASE1.