ICANN publishes the complete list of TLD registries and domain name registrars. All new GTLD registries and registrars must support DNSSEC. ICANN publishes the complete list of TLDs, TLD registries, and domain name registrars. Most local Internet registries are also Internet service providers. A registrar operates in accordance with the guidelines of the designated domain name registries. Registries and DNA databases have been developed for this purpose. Several other top-level domain registries started accepting registrations in 2004 and 2005. Specific details of which records are stored vary among domain name registries. Anyone may use these addresses without approval from regional or local Internet registries. IANA delegates allocations of IP address blocks to regional Internet registries (RIRs). It is used for data coordination among government registries. The RIRs assign smaller blocks to local Internet registries that distributes them to users. Regional Internet registries (RIRs) were established for five regions of the world. Cancer diagnoses were verified using Ohio/West Virginia cancer registries. Evidence to support the effectiveness of public sex offender registries is limited and mixed.