Less than 5% occur as part of hereditary familial or idiopathic multitumor syndromes. In children statins are effective at reducing cholesterol levels in those with familial hypercholesterolemia. Confirmation of the familial form is by genetic testing. Marina Biotech developed CEQ508 which is used to treat Familial Adenomatous Polyposis. There are extremely rare instances of familial Swyer syndrome. She speaks on parental and familial issues. Such behavior may contribute to cycles of familial violence and trauma. This accumulation leads over time to one form of familial renal amyloidosis. Women's identity is seen through the prism of familial relationships. Screenings are adjusted to individual and familial risk factors. This disease has multiple types including light chain, familial, and senile. This deformity is more common in women and people with familial ligamentous laxity. The detection of p16 inactivation in familial melanoma supplied further evidence. Critics also claim that racial profiling could occur on account of familial DNA testing. Also noteworthy is the report of familial presence of parasomnia.