Generic groups created by cell biologist are teratogens, mutagens, allergens, and carcinogens. Serum-soluble genotoxic teratogens produce congenital disorders, and in white blood cells causes immune system damage. Common teratogens are alcohol, retinoic acid, ionizing radiation or hyperthermic stress. Many teratogens exert specific effects on the fetus by epigenetic mechanisms. Known teratogens include&colon; thalidomide, mercury, alcohol, lead, and polychlorinated biphenyls (PCBs). Congenital amputation can also occur due to maternal exposure to teratogens during pregnancy. Some of these include intrauterine infection, teratogens, and some congenital syndromes. The vitamin K antagonists can cause birth defects (teratogens). There is little evidence that vanadium or vanadium compounds are reproductive toxins or teratogens. Physical effects of teratogens are common, but endocrine effects are harder to measure. Anything (including drugs) that can cause permanent deformities in the fetus are labeled as teratogens. The substance that causes developmental toxicity from embryonic stage to birth is called teratogens. The treatment for scleroderma often includes known teratogens such as cyclophosphamide, methotrexate, mycophenolate, etc. Inheritance can play a part as can prenatal exposure to hormones and teratogens. Factors that precipitate include genetics, and maternal exposure to teratogens.