Deficient ATM expression causes severe meiotic disruption during prophase I. Lamin subunits disassembled in prophase are inactivated and sequestered during mitosis. Like mitosis, meiosis also has distinct stages called prophase, metaphase, anaphase, and telophase. Prometaphase is the phase of mitosis following prophase and preceding metaphase, in eukaryotic somatic cells. These stages are prophase, prometaphase, metaphase, anaphase, and telophase. Mitosis is composed of many stages which include, prophase, metaphase, anaphase, telophase, and cytokinesis, respectively. The human homolog, hsSgo1, associates with centromeres during prophase and disappears when anaphase starts. Many species arrest meiosis in diplotene of prophase I until ovulation. Primordial follicles contain oocytes that are at an intermediate (prophase I) stage of meiosis. Germ cells also stop dividing at prophase of meiosis, leading to reproductive sterility. Synapsis takes place during prophase I of meiosis. It occurs in the stage of meiotic prophase I in ootidogenesis. At prophase and metaphase, survivin is mainly nuclear in location. The nucleolus also disappears during early prophase. In mitotic prophase I of plants, this band disappears.