If papules and pustules persist, then sometimes isotretinoin can be prescribed. As a result, the prisoners developed inflammatory pustules and papules. It can proliferate in sebum and cause inflamed pustules (pimples) characteristic of acne. Pustular psoriasis appears as raised bumps filled with noninfectious pus (pustules). Signs of scalp inflammation include redness, scaling, and pustules. Occasionally, secondary infection with bacteria occurs with concurrent pustules and impetigo. Pemphigus foliaceus in animals produces clusters of small vesicles that quickly evolve into pustules. This pellicle may be decorated with pustules, warty projections, spines or tubercules. Comedones can become irritated, swollen, infected, and ultimately pustules. Irritant reactions include miliaria (sweat rash), follicular pustules, and burn-like reactions. In midsummer, aecia appear on the epidermis of spruce needles as orange pustules. The obese and disheveled Baron is overtly unstable, and covered in oozing pustules. The texture throughout is smooth, lacking bumps or pustules. They include pustules (small protrusions), scales, and striations. Its species have leaves with pustules or spots, rounded seeds and contain homoisoflavanones.