The iris inner smaller circle-circumference changes size when constricting or dilating. Edinger-Westphal nucleus reacts to taste stimuli by dilating and constricting the pupils. They are potent direct vasoconstrictors, constricting arteries and veins and increasing blood pressure. Compression garments can also be of benefit by constricting blood pressures with external body pressure. ESCRTIII forms a spiral shaped structure constricting the neck. The differential diagnosis includes the much more common constricting or obstructing carcinoma. Active lives required less constricting clothing and required simpler and more streamlined clothing. Ancient Greeks applied the term to large, constricting snakes. Selective breeding for dog breeds caused constricting breed-specific bottlenecks. Later, as the fetus grows but the bands do not, the bands become constricting. In October 2018, it was discovered that an unusually large fatberg was constricting the sewers. Nelson found the structure of a permanent band constricting. The prognosis depends on the location and severity of the constricting bands. From ages six to ten, Isadora attended school, but she dropped out, finding it constricting. Chan, angry with this betrayal and with S.H.I.E.L.D. for constricting him, attacks both.