However, KMT2D is dispensable for maintaining embryonic stem cell and somatic cell identity. This segment is dispensable for excision but essential for integration, including Recombinase-mediated cassette exchange. The kinase domain, while important for necroptotic (programmed necrotic) functions, appears dispensable for pro-survival roles. In the open pan-genome, genes may be further characterized as dispensable or strain specific. The very small genome of "M. genitalium" possesses dispensable genes. Secondary in contrast to primary metabolites are dispensable and not absolutely required for survival. A striking aspect of "Zymoseptoria tritici" genetics is the presence of many dispensable chromosomes. NYC saw the Putnam Division as a dispensable stepchild. In it, he suggested that meaning was nothing more than a vague and dispensable notion. Stifel found them very useful for mathematics, and not dispensable. The dairy section was criticized by some as similarly dispensable. The character treats men as dispensable entities, similar to how men usually treat women. The distributor is required to keep accurate accounts, but dispensable to have a bonded warehouse. The signing of the Oregon Boundary Treaty in 1846 made him dispensable. Bombs, Recon cameras, and dive brakes were all dispensable.