The drug disulfiram (Antabuse) prevents the oxidation of acetaldehyde to acetic acid. Sertraline concentrate contains alcohol, and is therefore contraindicated with disulfiram (Antabuse). Pharmacological treatments for SUD include the use of acamprosate, buprenorphine, disulfiram, LAAM, methadone, and naltrexone. The medications acamprosate, disulfiram or naltrexone may also be used to help prevent further drinking. Many disulfiram-like drugs act as inhibitors of acetaldehyde dehydrogenase similarly to disulfiram. The tetraethyl derivative, known as disulfiram, is commonly used to treat chronic alcoholism. Alcohol consumption can cause a disulfiram like reaction with benznidazole. Cases of disulfiram neurotoxicity have also occurred, causing extrapyramidal and other symptoms. When combined with disulfiram (an aversive procedure) community reinforcement showed remarkable effects. Other inhibitors include diethyldithiocarbamate (in cancer), and disulfiram (in alcoholism). Consuming "Coprinopsis atramentaria" within a few hours of alcohol results in a "disulfiram syndrome". ALDH1 is strongly inhibited by disulfiram, while ALDH2 is resistant to its effect. DBH is inhibited by disulfiram, tropolone, and, most selectively, by nepicastat. It forms in the liver as a side-effect of disulfiram treatment.