Vaccines that treat existing cancer are known as "therapeutic" cancer vaccines. The vaccine is safe to give at the same time as other vaccines. The administration of vaccines is called vaccination. Rubella infections are prevented by active immunisation programs using live attenuated virus vaccines. These help in developing influenza countermeasures such as vaccines, therapies and diagnostic tools. The inactivated polio vaccines are very safe. This significant breakthrough ultimately allowed for the development of the polio vaccines. Growing viruses in cell cultures allowed preparation of purified viruses for the manufacture of vaccines. Goal 3 aims to achieve universal health coverage, including access to essential medicines and vaccines. A number of safe and effective oral vaccines for cholera are available. Other drugs included antitoxins, a few biological vaccines, and a few synthetic drugs. Two meningococcal conjugate vaccines (MCV4) are licensed for use in the U.S. As with other live-virus vaccines, immunity initiated by OPV is probably lifelong. Two main approaches are used to attempt to improve the efficacy of available vaccines. Therefore, HSPs may be useful for increasing the effectiveness of cancer vaccines.