PI3K / Akt and Erk MAP kinase pathways. NMDA receptors activate ERK through a different but interrelated Ras-Raf-MEK-ERK pathway. The acronym MEK derives from MAPK/ERK Kinase. NPY affects neurogenesis by interacting with ERK kinase signaling pathways. Examples of proto-oncogenes include RAS, WNT, MYC, ERK, and TRK. Raf-1, ERK, JNK, p38, c-fos, c-jun and many more. One of the protective pathways is the PI3K/AKT pathway; another is the RAS/MEK/ERK pathway. JAK-STAT signalling can also integrate with the MAPK/ERK pathway. Raf (MAPKKK), which activates Mek (MAPKK), which activates Erk (MAPK). The activity PPARG can be regulated via phosphorylation through the MEK/ERK pathway. Rsks are serine/threonine kinases and are activated by the MAPK/ERK pathway. It increases the phosphorylation of JNK, ERK and MAPK "in vitro" breast cancer models. Erk south southwest of Hareira, at dawn. Grb2 then functions to allow the MAPK/ERK pathway to progress. SMAD4 is a substrate of the Erk/MAPK kinase and GSK3.