With respect to acute toxicity, simple alcohols have low acute toxicities. Two major dose limiting toxicities of anthracyclines include myelosuppression and cardiotoxicity. The major toxicities of approved IMiDs are peripheral neuropathy, thrombocytopenia, anaemia and venous thromboembolism. Neurologic lameness may be the result of infection, trauma, toxicities, or congenital disease. Other causative conditions include infections, toxicities, antiphospholipid syndrome, cryoglobulinemia, neoplasms. Elemental selenium and most metallic selenides have relatively low toxicities because of low bioavailability. Symptoms associated with both toxicities include nausea, blurred vision, fatigue, weight-loss, menstrual abnormalities etc. Late manifestation include liver and kidney toxicities. Esters of adipic acid exhibit low acute toxicities in animal models. Axicabtagene treatment carries a risk for cytokine release syndrome (CRS) and neurological toxicities. Diazepam however showed relatively weak fetal toxicities. In clinical trials, 90% of patients had dermatological toxicities and 15% of those were severe. There were no dose-limiting toxicities seen at this dosage. Immunotherapies as a group have off-target effects and toxicities common to them. Toxicities can also occur with collection of morels.