They may be administered orally, intravenously or topically. It can be used topically or orally. It can be taken orally or applied topically with increased effectiveness. Marbofloxacin can be used both orally and topically. Most treatments are with antifungal medications either topically or by mouth. It can be given intravenously, by injection into a muscle, or topically. The topically applied azole drugs are more effective than nystatin. Local antifungals are usually administered topically or vaginally, depending on the condition being treated. Strontium has been shown to inhibit sensory irritation when applied topically to the skin. Magnesium hydroxide is useful against canker sores (aphthous ulcer) when used topically. It was inhaled, ingested, injected, and applied topically. It was applied topically to alleviate ulcerative symptoms. Sulfamethoxazole is well-absorbed when administered topically. One example of an antibiotic that may be applied topically is chloramphenicol. Retinyl palmitate is also a constituent of some topically applied skin care products.