Smoking, being overweight, and eating unhealthily may also contribute to more rapid degeneration. She begins losing weight and quickly becomes an unhealthily low body weight. Erik is a young writer unhealthily dependent on his girlfriend Joanna. As immigration continued, the area became unhealthily overcrowded, resulting in dilapidated tenements and pollution. She appeared unhealthily thin, weighing only 90 pounds when she was 25. These astrocytes have an unhealthily large amount of GFAP that affects astrocyte formation and function.