Typical viruses include respiratory syncytial virus, rhinovirus, influenza, and others. It most often includes adenovirus, rhinovirus, influenza, parainfluenza, coronavirus, and respiratory syncytial virus. Human rhinovirus infection of airway epithelium induces ICAM-1. Viruses that may cause adenoiditis include adenovirus, rhinovirus and paramyxovirus. Notable examples are "Enterovirus" (including Rhinovirus and Poliovirus), "Aphthovirus", "Cardiovirus", and "Hepatovirus" genera. Interferon-alpha used intranasally was shown to be effective against human rhinovirus infections. Most sinus findings are reversible consistent with a self-limited viral process typical of rhinovirus colds. Typically, these infections are rhinovirus, parainfluenza, or influenza. In terms of pathophysiology, rhinovirus infection resembles the immune response. The genomes of all known human rhinovirus strains have been sequenced. High rates of asthma attacks due to rhinovirus infection are also found in adults. Rhinovirus C, unlike the A and B species, may be able to cause severe infections. Human rhinovirus is most contagious during the autumn and winter months. In 40-90% cases, an adult infected with rhinovirus has virus on their hands. By comparison, Rhinovirus is 1/10 as large as a typical "Poxviridae" virion.