Poor posture can lead to injuries such as lordosis, kyphosis, and scoliosis. Spinal curvatures of kyphoscoliosis or lumbar lordosis may be present. Increased and decreased lumbar lordosis, inward curvature of the lower spine, has been seen. Holding the knee to the chest flattens out the lumbar lordosis and stabilizes the pelvis. Physical signs include deformities like triradiate pelvis and lordosis. Diagnosis includes a spin test, walking, heel walking, dorsiflexion range of motion, and lumbar lordosis. During lordosis, the spine curves dorsoventrally so that its apex points towards the abdomen. In the experiments where embryos did survive, spinal lordosis and lower motor functions were observed. Skeletal system developments often include lordosis, kyphoscoliosis, or pes cavus. For instance, GnRH molecule functions as a neurotransmitter in rats to elicit lordosis behavior. Under the action of estrogen in the hypothalamus, the lordosis reflex is uninhibited. Nearly all mammals display sex-dimorphic reproductive and sexual behavior (e.g., lordosis and mounting in rodents). In the brain, several regions modulate the lordosis reflex. These neurobiological processes induced by estradiol enable the tactile stimuli to trigger lordosis. Postpartum, the angle of the lordosis declines and can reach the angle prior to pregnancy.