They include accidental poisonings, drownings, traffic accidents, and suicides. Activated carbon is used to treat poisonings and overdoses following oral ingestion. These include suicides and accidental drug poisonings. Fatal poisonings and illnesses linked to intentional inhalation of trichloroethane have been reported. Worldwide, 30% of suicides are from pesticide poisonings. Ingestion of such spoiled meat can cause serious food poisonings, like botulism. There have been many instances of mass chlorine gas poisonings in industrial accidents. These were either accidental poisonings or assassination plots. They result in about 2.5 million poisonings and 20,000 to 125,000 deaths. Similar signs and symptoms have been observed in accidental human poisonings. Although fatal human poisonings are rare, several cases have been documented. Historically, however, several incidents have resulted in many poisonings. In 2013, 3.3 million cases of unintentional human poisonings occurred. Seizures and coma may also occur in severe poisonings. Bromazepam has also been responsible for accidental poisonings in companion animals.