Numerous pharmaceutical compounds are marketed as appetite suppressants. Over-the-counter medications for neutralizing acids (antacids) and acid suppressants (H-2 blockers) may be used. Allen developed bulimia and used cocaine and other appetite suppressants to decrease her eating. They are used variously as antidepressants, anxiolytics, antiobsessionals, appetite suppressants, and entactogens. Early anorectics (appetite suppressants) were fenfluramine and phentermine. Most are appetite suppressants that act on one or more neurotransmitters. Jamil has been a critic of diet shakes and appetite suppressants. Sympathomimetic anoretics (appetite suppressants) are used in the short-term treatment of obesity. When Rosetta catches Ringo using appetite suppressants, she tells Frazer about his condition. Cough suppressants are used if the cough is not productive. Cough suppressants can increase the risk of choking. As with gaseous fire suppressants, condensed aerosol suppressants use clean agents to suppress the fire. Cough suppressants focus their action on the cough center. Transplantation necessitates the use of immune suppressants (ciclosporin or tacrolimus). Condensed aerosol suppressants, as with gaseous suppressants, use four methods to extinguish fires.