Ulcerative colitis or Crohn's disease may cause colonic obstruction. It is used to treat inflammatory bowel disease, including ulcerative colitis and Crohn's disease. Anaemia is commonly present in both ulcerative colitis and Crohn's disease. Dietary patterns are associated with a risk for ulcerative colitis. He was diagnosed with ulcerative colitis in 2006. The best test for diagnosis of ulcerative colitis remains endoscopy. Adalimumab may be effective and well tolerated in ulcerative colitis. Budesonide assists in the induction of remission in people with active ulcerative colitis. It may also be used to prevent flares in those with ulcerative colitis. This suggests that ICAM-1 is a potential therapeutic target in the treatment of ulcerative colitis. Approximately 70% of people with ulcerative colitis will have moderately active disease at presentation. The first description of ulcerative colitis occurred around the 1850s. Colitis (inflammation of the colon) occurs commonly. Ischemia of the large intestine may result in an inflammatory process known as ischemic colitis. Serious side effects may include "Clostridium difficile" colitis or anaphylaxis.