Cortisol, prolactin, and oxytocin quantities in serum are increased by MDMA. Both prolactin and oxytocin stimulate milk production in women. Low levels of dopamine lead to high levels of prolactin. They are most effective in those whose pituitary tumours cosecrete prolactin. High concentrations of dopamine and low concentrations of prolactin (and serotonin) can also cause FHA. The pigmentation of hair is controlled by the hormone prolactin and colour genetics. Allowed for by estrogen, progesterone and prolactin work together to complete lobuloalveolar development during pregnancy. The main stimulus for prolactin secretion is suckling, the effect of which is neuronally mediated. In general, dopamine inhibits prolactin but this process has feedback mechanisms. Human prolactin receptors are insensitive to mouse prolactin. The higher the prolactin level the lower the chance of normalizing serum prolactin. Diazepam also decreases prolactin release in rats. Periodic monitoring of liver enzymes and prolactin levels may be advisable during cyproterone acetate therapy. It appears that, in structure, GH is evolutionarily homologous to prolactin and chorionic somatomammotropin. Chlordiazepoxide also decreases prolactin release in rats.