Postherpetic neuralgia is thought to be due to nerve damage caused by herpes zoster. There is a common association with herpes zoster. Brivudine is used for the treatment of herpes zoster in adult patients. Herpes zoster virus can attack the ciliary ganglion. In 2013 there were 140 million cases of chickenpox and herpes zoster worldwide. The rash caused by herpes zoster (Shingles) follows such dermatomal lines. PHN is the most common long-term complication of herpes zoster. There is a short-term risk of developing herpes zoster (shingles) following vaccination. Rarely, OM of the jaws may be a complication of trigeminal herpes zoster. Herpes Zoster is the virus which causes shingles and chicken pox. In the United States each year approximately 1,000,000 individuals develop herpes zoster. Herpes zoster (shingles) may also cause posterior hip pain. Herpes zoster ophthalmicus (HZO), also known as ophthalmic zoster, is shingles involving the eye. The herpes zoster vaccine is recommended for prevention in those over the age of 50. Immunologic side effects have included herpes zoster (shingles) and case reports of opportunistic infections.