Antibiotic stewardship programmes appear useful in reducing rates of antibiotic resistance. Sometimes, multiple antibiotics are used in case there is resistance to one antibiotic. Azithromycin is an azalide, a type of macrolide antibiotic. Doxycycline is a broad-spectrum antibiotic, of the tetracycline class. The initial antibiotic of choice is typically amoxicillin. Overshooting responds to treatment with tetracycline, a common broad-spectrum antibiotic. Adverse effects are similar to those of other members of the tetracycline antibiotic group. Common options include clindamycin, a combination of a beta-lactam antibiotic and metronidazole, or an aminoglycoside. This followed their discovery of erythromycin, another antibiotic. An example of a commonly used broad-spectrum antibiotic is ampicillin. Cefpodoxime is an oral, third-generation cephalosporin antibiotic. They may also be useful in preventing and treating antibiotic associated diarrhea. Treatment is typically with the antibiotic streptomycin. Evidence to support the use of antibiotic eye ointment is poor. Whether rifampicin is an effective antibiotic to take for treatment is uncertain.