It is capable of producing enterotoxins which are thermolabile or thermostable. This is done by intentionally creating mutants which are thermolabile. This gene encodes a phenol sulfotransferase with thermolabile enzyme activity. Each is a thermolabile protein of ~80kDa. In pharmaceutical compounds, heat generated during grinding may lead to degradation of thermolabile compounds. Thereby, most sv-LAAOs are considered to be thermolabile enzymes. Thiamine is degraded by thermolabile thiaminases (present in raw fish and shellfish). It does not result in thermolabile MTHFR and does not appear to affect homocysteine levels. Because of the relatively low pressure involved, many supercritical fluid methods can incorporate thermolabile materials. Enzymes are also thermolabile and lose their activity when the temperature rises.