Mossy fibers are the axons of granule cells. The Golgi cell acts by altering the mossy fibre - granule cell synapse. TrkB is responsible for the maintenance of normal synaptic connectivity of the dentate granule cells. The contacts between mossy fibers and granule cell dendrites take place within structures called glomeruli. In the adult brain, the endocannabinoid system facilitates the neurogenesis of hippocampal granule cells. Some of the basal dendrites of the granule cells curve up into the molecular layer. The mast cell granule can now fuse with the plasma membrane. This irreversibly dissolves the starch granule in water. Both epilepsy and depression show a disrupted production of adult-born hippocampal granule cells. Eosinophils lacking XBP1 exhibit defects in granule proteins. Loss of mossy cells lowers the threshold of action potentials of the granule cells. This dispersed germinal matrix is the source of granule cells from that point on. There are a number of proteins that are within the dense granule membrane. Sodium chlorate comes in dust, spray and granule formulations. The size and shape of the starch granule varies by botanical source.