Sirolimus also appears to be effective for the treatment chylous effusions and lymphangioleiomyomatosis. Chylous ascites and chylothorax rarely occur. Rarely chylous ascites (0.6%). Lymph node aspirate and chylous fluid may also yield microfilariae. Cytology of chylous fluids, aspirated abdominal nodes or lymphatic masses can also be diagnostic. Chylous ascites heals best if the lymphatic vessel involved is closed. Small stable chylous effusions rarely require intervention once the LAM diagnosis is made.