The femoral artery is susceptible to peripheral arterial disease. Peripheral neuropathy and mononeuritis multiplex may occur. Another study found it also effective for healing limb ulcers caused by peripheral vascular disease. This occurs especially in cardiac failure with peripheral congestion. Stimulants enhance the activity of the central and peripheral nervous systems. Recent investigations discovered opioid receptors on peripheral sensory neurons. Phenytoin is known to be a causal factor in the development of peripheral neuropathy. Dry beriberi causes wasting and partial paralysis resulting from damaged peripheral nerves. Devices with peripheral and central roles have different power requirements. Acetylcholine appears to function as an excitatory neurotransmitter in both the peripheral and central synapses. SSRIs inhibit proinflammatory cytokine production which leads to less activation of microglia and peripheral macrophages. It is linked to palsy, which is a result of peripheral neuropathy. No potential for peripheral neuropathy has been found. Analgesic drugs act in various ways on the peripheral and central nervous systems. LDL circulates and is absorbed by the liver and peripheral cells.