T lymphocytes, macrophages, and neutrophils. They engage in cross talk with other immune cells, like dendritic cells, neutrophils and lymphocytes. II transmembrane protein expressed on cytotoxic T lymphocytes. It presents epitopes to killer T cells, also called cytotoxic T lymphocytes (CTLs). They promote the development and differentiation of T and B lymphocytes, and hematopoietic cells. Pathogenic process occurs due to circulating CD8 lymphocytes within the salivary gland. It results in proliferation and differentiation of B lymphocytes and production of antibodies. The adjective used for the tissues where lymphocytes are formed is "lymphoid". Phytohaemagglutinin stimulated peripheral blood lymphocytes are used. The third mechanism is apoptosis of lymphocytes. Classical MHC molecules present epitopes to the TCRs of CD8+ T lymphocytes. Lymph also carries lymphocytes, and other immune system agents. This causes large numbers of tumor-infiltrating lymphocytes (TILs) to be found in the tumor microenvironment. Classic molecules present peptides to CD4+ lymphocytes. This leads to a clonal expansion of malignant B lymphocytes.