Blood dyscrasias such as agranulocytosis, leukopenia and neutropenia are possible with thioridazine treatment. Adverse effects may include allergic reactions, vitamin B insufficiency, agranulocytosis and aplastic anemia. Serious, though rare, side effects include aplastic anemia, pancreatitis, agranulocytosis, and angioedema. Its most serious rare side effect is bone marrow suppression causing neutropenia and agranulocytosis. Its notable side effects include a risk of agranulocytosis and aplastic anemia. Levamisole suppresses the production of white blood cells, resulting in neutropenia and agranulocytosis. "Hematologic"&colon; Agranulocytosis; bone marrow depression; leukopenia;thrombocytopenia; purpura; eosinophilia. The terms agranulocytosis, granulocytopenia and neutropenia are sometimes used interchangeably. Clozapine-induced agranulocytosis can be transient. Likewise rarely it has been associated with agranulocytosis, erythema multiforme and toxic epidermal necrolysis. Clozapine carries a black box warning for drug-induced agranulocytosis. Acquired agranulocytosis is much more common than congenital form. Agranulocytosis implies a more severe deficiency than granulocytopenia. Several cases of severe agranulocytosis associated with cocaine use have been reported since 2006. Rare cases of agranulocytosis have also been reported in medical literature.