Symptoms include fever, malaise, rash, arthralgia, and muscle tenderness. Symptoms include fever, headache, arthralgia, and local as well as generalised pain. The extent of its role varies depending on the specific cause of the arthralgia. It is characterized by fever, myalgia, headache, and arthralgia. Colorado tick fever virus can cause a fever, chills, headache, photophobia, myalgia, arthralgia, and lethargy. Other features include excessive sweating, arthralgia and gastrointestinal abnormalities. About one-third of patients develop symptoms such as fatigue, arthralgia and jaundice. The most common side effects are sweating, hot flashes, arthralgia (joint pain), and fatigue. The eruptions may be accompanied by fever, arthralgia or other systemic symptoms. When attempting to establish the cause of the arthralgia, the emphasis is on the interview. Inbred mice infected with RRV develop hind-limb arthritis/arthralgia. Myalgia (muscular pain) and arthralgia (joint pain) are rare side effects. The most common symptoms were rash, fever, arthralgia, and conjunctivitis, and no deaths were reported. Other minor Jones Criteria are fever, elevated ESR and arthralgia. The WHO guidelines advise to distinguish non-inflammatory arthralgia from inflammatory arthritis.