Phenobarbital is a cytochrome P450 hepatic enzyme inducer. Nevirapine is an inducer of cytochrome P450 isoenzymes CYP3A4 and CYP2B6. YopO is a potent inducer of human macrophage apoptosis. Inhibition of lamin assembly itself is an inducer of apoptosis. An addition of the inducer IPTG inactivates the LacI repressor. The reason behind this action is because modafinil is an inducer of the CYP3A4 enzymes. Thus, repressor with inducer bound is stabilized in the non-DNA-binding conformation. Trehalose has long been known as an autophagy inducer that acts independently of mTOR. Platelet derived growth factor is a major inducer of CCL2 gene. Nodal, a known mesodermal inducer of the TGFB superfamily, has been implicated in streak formation. Meropenem, like other carbapenems, is a potent inducer of multidrug resistance in bacteria. The velocity of the LOX was increased through the inducer and impeller. Wnt signaling is an inducer of EMT, particularly in mammary development. The conformation is purely determined by the binding of allosteric inducer arabinose. For example, UV irradiation is a potent inducer for elevated c-jun expression.