A fluorophore can be directly conjugated to the primary antibody. These modified compounds are then conjugated to polar compounds in phase II reactions. It is the simplest conjugated diene. A polyene is a molecule with multiple conjugated double bonds. Magnetic nanoparticles can be conjugated with carbohydrates and used for detection of bacteria. Pethidine's metabolites are further conjugated with glucuronic acid and excreted into the urine. It can also be conjugated to amino acids in some biological contexts. These metabolites are conjugated with glucuronide, and are excreted primarily in the urine. Ketamine and its metabolites are also conjugated. Viral hepatitis can also cause the rise in conjugated bilirubin. One of the most impressive of techniques exploits anisotropic optical characteristics of conjugated polymers. These, in turn, are conjugated with glycine, taurine, glucuronic acid, or sulfate. Verbs are conjugated for person by adding affixes. Sentence structure determines syntactical relations and verbs are not conjugated. Preferably, the toxins are conjugated to avail excretion in bile or urine.