What Spaniard fought the Tiwa Indians and saw the Colorado River?
Francisco Vázquez de Coronado
Title: Francisco Vázquez de Coronado
Passage: Francisco Vázquez de Coronado y Luján (1510 – 22 September 1554) was a Spanish conquistador and explorer who led a large expedition from Mexico to present-day Kansas through parts of the southwestern United States between 1540 and 1542.  Vázquez de Coronado had hoped to reach the Cities of Cíbola, often referred to now as the mythical Seven Cities of Gold, which is a term not invented until American gold-rush days in the 1800s.  His expedition marked the first European sightings of the Grand Canyon and the Colorado River, among other landmarks.  His name is often Anglicized as "Vasquez de Coronado".
Title: Bill Williams River
Passage: The Bill Williams River is a 46.3 mi river in west-central Arizona where it, along with its tributary, the Santa Maria River, form the boundary between Mohave County to the north and La Paz County to the south.  It is a major drainage westwards into the Colorado River of the Lower Colorado River Valley south of Hoover Dam and Lake Mead, and the drainage basin covers portions of northwest, and west-central Arizona.  The equivalent drainage system paralleling the east–west lower reaches of the Bill Williams is the Gila River, which flows east-to-west across central Arizona, joining the Colorado River in the southwest at Yuma.  The confluence of the Bill Williams River with the Colorado is north of Parker, and south of Lake Havasu City.
Title: Tiguex War
Passage: The Tiguex War was the second named war – after the Battle of Mabila Oct 1540 – between Europeans and Native Americans in what is now the United States.  It was fought in the winter of 1540-41 by the expedition of Francisco Vázquez de Coronado against the twelve or thirteen pueblos of Tiwa Indians as well as other Puebloan tribes along both sides of the Rio Grande, north and south of present-day Bernalillo, New Mexico, in what was called the Tiguex Province.  The only book-length treatment of the Tiguex War is in the historical novel, Winter of the Metal People.
Francisco Vázquez de Coronado Tiguex War