{"action":"created","issue":{"url":"https://api.github.com/repos/greenelab/adage-server/issues/145","repository_url":"https://api.github.com/repos/greenelab/adage-server","labels_url":"https://api.github.com/repos/greenelab/adage-server/issues/145/labels{/name}","comments_url":"https://api.github.com/repos/greenelab/adage-server/issues/145/comments","events_url":"https://api.github.com/repos/greenelab/adage-server/issues/145/events","html_url":"https://github.com/greenelab/adage-server/issues/145","id":226867084,"number":145,"title":"Take absolute value of all activity values?","user":{"login":"mhuyck","id":1151166,"avatar_url":"https://avatars2.githubusercontent.com/u/1151166?v=3","gravatar_id":"","url":"https://api.github.com/users/mhuyck","html_url":"https://github.com/mhuyck","followers_url":"https://api.github.com/users/mhuyck/followers","following_url":"https://api.github.com/users/mhuyck/following{/other_user}","gists_url":"https://api.github.com/users/mhuyck/gists{/gist_id}","starred_url":"https://api.github.com/users/mhuyck/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/mhuyck/subscriptions","organizations_url":"https://api.github.com/users/mhuyck/orgs","repos_url":"https://api.github.com/users/mhuyck/repos","events_url":"https://api.github.com/users/mhuyck/events{/privacy}","received_events_url":"https://api.github.com/users/mhuyck/received_events","type":"User","site_admin":false},"labels":[{"id":435107029,"url":"https://api.github.com/repos/greenelab/adage-server/labels/question","name":"question","color":"cc317c","default":true}],"state":"open","locked":false,"assignee":null,"assignees":[],"milestone":null,"comments":2,"created_at":"2017-05-07T15:08:13Z","updated_at":"2017-05-08T15:23:32Z","closed_at":null,"body":"Should we be taking the absolute value of all activity values before performing calculations? The original design kept negative activity values in the database while separating positive and negative node/signatures.\r\n\r\nThis question arises in the context of the volcano plot. Currently, the difference in activity for a node between two groups of samples is computed by taking the mean activity for each group and subtracting. The question is: should we take the absolute value first?"},"comment":{"url":"https://api.github.com/repos/greenelab/adage-server/issues/comments/299898816","html_url":"https://github.com/greenelab/adage-server/issues/145#issuecomment-299898816","issue_url":"https://api.github.com/repos/greenelab/adage-server/issues/145","id":299898816,"user":{"login":"dongbohu","id":15133253,"avatar_url":"https://avatars0.githubusercontent.com/u/15133253?v=3","gravatar_id":"","url":"https://api.github.com/users/dongbohu","html_url":"https://github.com/dongbohu","followers_url":"https://api.github.com/users/dongbohu/followers","following_url":"https://api.github.com/users/dongbohu/following{/other_user}","gists_url":"https://api.github.com/users/dongbohu/gists{/gist_id}","starred_url":"https://api.github.com/users/dongbohu/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/dongbohu/subscriptions","organizations_url":"https://api.github.com/users/dongbohu/orgs","repos_url":"https://api.github.com/users/dongbohu/repos","events_url":"https://api.github.com/users/dongbohu/events{/privacy}","received_events_url":"https://api.github.com/users/dongbohu/received_events","type":"User","site_admin":false},"created_at":"2017-05-08T15:23:32Z","updated_at":"2017-05-08T15:23:32Z","body":"Actually @tj8901nm created a new activity file in which all activity values are positive, but when deploying the database, we still used the original activity sheet. Should we import both activity files into the database (with different machine learning models)? "}}
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