{"action":"opened","issue":{"url":"https://api.github.com/repos/chemalot/chemalot/issues/3","repository_url":"https://api.github.com/repos/chemalot/chemalot","labels_url":"https://api.github.com/repos/chemalot/chemalot/issues/3/labels{/name}","comments_url":"https://api.github.com/repos/chemalot/chemalot/issues/3/comments","events_url":"https://api.github.com/repos/chemalot/chemalot/issues/3/events","html_url":"https://github.com/chemalot/chemalot/issues/3","id":222267903,"number":3,"title":"InChi and tautomers","user":{"login":"jw-feng","id":15355450,"avatar_url":"https://avatars2.githubusercontent.com/u/15355450?v=3","gravatar_id":"","url":"https://api.github.com/users/jw-feng","html_url":"https://github.com/jw-feng","followers_url":"https://api.github.com/users/jw-feng/followers","following_url":"https://api.github.com/users/jw-feng/following{/other_user}","gists_url":"https://api.github.com/users/jw-feng/gists{/gist_id}","starred_url":"https://api.github.com/users/jw-feng/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/jw-feng/subscriptions","organizations_url":"https://api.github.com/users/jw-feng/orgs","repos_url":"https://api.github.com/users/jw-feng/repos","events_url":"https://api.github.com/users/jw-feng/events{/privacy}","received_events_url":"https://api.github.com/users/jw-feng/received_events","type":"User","site_admin":false},"labels":[],"state":"open","locked":false,"assignee":null,"assignees":[],"milestone":null,"comments":0,"created_at":"2017-04-18T00:29:06Z","updated_at":"2017-04-18T00:29:06Z","closed_at":null,"body":"Hi,\r\n\r\nBased on this slide from Roger Sayle that was presented at RDKit 2016 UGM.  InChi sometimes fails to generate canonical strings for different tautomers.  Here the link to the full talk.  Going from mol to InChi and then back may not work for generating canonical tautomeric SMILES.\r\n\r\n![screen shot 2017-04-17 at 5 26 50 pm](https://cloud.githubusercontent.com/assets/15355450/25109673/3cfcc7fa-2393-11e7-9f64-c535e8d91227.png)\r\n\r\nJW"}}
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