{"action":"created","issue":{"url":"https://api.github.com/repos/greenelab/deep-review/issues/523","repository_url":"https://api.github.com/repos/greenelab/deep-review","labels_url":"https://api.github.com/repos/greenelab/deep-review/issues/523/labels{/name}","comments_url":"https://api.github.com/repos/greenelab/deep-review/issues/523/comments","events_url":"https://api.github.com/repos/greenelab/deep-review/issues/523/events","html_url":"https://github.com/greenelab/deep-review/issues/523","id":231824727,"number":523,"title":"This point on domain adaptation doesn't make sense to me","user":{"login":"jisraeli","id":5925689,"avatar_url":"https://avatars0.githubusercontent.com/u/5925689?v=3","gravatar_id":"","url":"https://api.github.com/users/jisraeli","html_url":"https://github.com/jisraeli","followers_url":"https://api.github.com/users/jisraeli/followers","following_url":"https://api.github.com/users/jisraeli/following{/other_user}","gists_url":"https://api.github.com/users/jisraeli/gists{/gist_id}","starred_url":"https://api.github.com/users/jisraeli/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/jisraeli/subscriptions","organizations_url":"https://api.github.com/users/jisraeli/orgs","repos_url":"https://api.github.com/users/jisraeli/repos","events_url":"https://api.github.com/users/jisraeli/events{/privacy}","received_events_url":"https://api.github.com/users/jisraeli/received_events","type":"User","site_admin":false},"labels":[{"id":443706109,"url":"https://api.github.com/repos/greenelab/deep-review/labels/study","name":"study","color":"0e8a16","default":false}],"state":"open","locked":false,"assignee":{"login":"agitter","id":3532898,"avatar_url":"https://avatars3.githubusercontent.com/u/3532898?v=3","gravatar_id":"","url":"https://api.github.com/users/agitter","html_url":"https://github.com/agitter","followers_url":"https://api.github.com/users/agitter/followers","following_url":"https://api.github.com/users/agitter/following{/other_user}","gists_url":"https://api.github.com/users/agitter/gists{/gist_id}","starred_url":"https://api.github.com/users/agitter/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/agitter/subscriptions","organizations_url":"https://api.github.com/users/agitter/orgs","repos_url":"https://api.github.com/users/agitter/repos","events_url":"https://api.github.com/users/agitter/events{/privacy}","received_events_url":"https://api.github.com/users/agitter/received_events","type":"User","site_admin":false},"assignees":[{"login":"agitter","id":3532898,"avatar_url":"https://avatars3.githubusercontent.com/u/3532898?v=3","gravatar_id":"","url":"https://api.github.com/users/agitter","html_url":"https://github.com/agitter","followers_url":"https://api.github.com/users/agitter/followers","following_url":"https://api.github.com/users/agitter/following{/other_user}","gists_url":"https://api.github.com/users/agitter/gists{/gist_id}","starred_url":"https://api.github.com/users/agitter/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/agitter/subscriptions","organizations_url":"https://api.github.com/users/agitter/orgs","repos_url":"https://api.github.com/users/agitter/repos","events_url":"https://api.github.com/users/agitter/events{/privacy}","received_events_url":"https://api.github.com/users/agitter/received_events","type":"User","site_admin":false}],"milestone":null,"comments":0,"created_at":"2017-05-27T20:04:10Z","updated_at":"2017-05-29T13:05:32Z","closed_at":null,"body":"```Without cell-specific features, another solution could be to use domain adaptation methods where the model trains on a source cell type and uses unsupervised feature extraction methods to predict on a target cell type``` in the `Transcription factors and RNA-binding proteins` subsection doesn't make sense to me. Non cell-specific features, absent cell-specific information, have the same distribution in source and target celltypes. Domain adaptation is used to normalize for differences between the source and target distribution, so I'd argue the opposite - that cell-specific features with different source and target distributions must be used to take advantage of this technique. Am I misunderstanding this point?"},"comment":{"url":"https://api.github.com/repos/greenelab/deep-review/issues/comments/304656793","html_url":"https://github.com/greenelab/deep-review/issues/523#issuecomment-304656793","issue_url":"https://api.github.com/repos/greenelab/deep-review/issues/523","id":304656793,"user":{"login":"agitter","id":3532898,"avatar_url":"https://avatars3.githubusercontent.com/u/3532898?v=3","gravatar_id":"","url":"https://api.github.com/users/agitter","html_url":"https://github.com/agitter","followers_url":"https://api.github.com/users/agitter/followers","following_url":"https://api.github.com/users/agitter/following{/other_user}","gists_url":"https://api.github.com/users/agitter/gists{/gist_id}","starred_url":"https://api.github.com/users/agitter/starred{/owner}{/repo}","subscriptions_url":"https://api.github.com/users/agitter/subscriptions","organizations_url":"https://api.github.com/users/agitter/orgs","repos_url":"https://api.github.com/users/agitter/repos","events_url":"https://api.github.com/users/agitter/events{/privacy}","received_events_url":"https://api.github.com/users/agitter/received_events","type":"User","site_admin":false},"created_at":"2017-05-29T13:05:32Z","updated_at":"2017-05-29T13:05:32Z","body":"@jisraeli I'm traveling and will look into the intentions of this sentence later this week."}}
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