<P> In the show 's last season , Samantha is diagnosed with breast cancer . She faces the challenge head - on , playing with her look by wearing outrageous wigs , hats , and headscarves after she loses her hair to chemotherapy . In one of the final episodes , she gives a speech for a cancer benefit dinner , and receives a standing ovation for removing her wig onstage and admitting that she was suffering with hot flashes . The audience appreciated her candor and honesty , and many of the women in the audience stood up and removed their own wigs . </P>
when does samantha get cancer in sex and the city
In the show 's last season