<P> The Frank -- Starling law of the heart ( also known as Starling 's law and the Frank -- Starling mechanism ) represents the relationship between stroke volume and end diastolic volume . The law states that the stroke volume of the heart increases in response to an increase in the volume of blood in the ventricles , before contraction ( the end diastolic volume ) , when all other factors remain constant . As a larger volume of blood flows into the ventricle , the blood stretches the cardiac muscle fibers , leading to an increase in the force of contraction . The Frank - Starling mechanism allows the cardiac output to be synchronized with the venous return , arterial blood supply and humoral length , without depending upon external regulation to make alterations . The physiological importance of the mechanism lies mainly in maintaining left and right ventricular output equality . </P>
what is frank starlings law of the heart
the stroke volume of the heart increases in response to an increase in the volume of blood in the ventricles , before contraction ( the end diastolic volume ) , when all other factors remain constant