<P> Creatine synthesis primarily occurs in the liver and kidneys . On average , it is produced endogenously at an estimated rate of about 8.3 mmol or 1 gram per day in young adults . Creatine is also obtained through the diet at a rate of about 1 gram per day from an omnivorous diet . Most of the human body 's total creatine and phosphocreatine stores are found in skeletal muscle , while the remainder is distributed in the blood , brain , and other tissues . </P>
where does creatine come from in the body
the liver and kidneys