analysis often referred benson group increment theory chemist sidney benson spent career developing concept ref name anslyn thermochemistry reactive intermediates carbocations carbanions radicals also interest physical organic chemists group increment data available radical systems ref name anslyn carbocation carbanion stabilities assessed using hydride ion affinities pk sub sub values respectively ref name anslyn conformational analysis one primary methods evaluating chemical stability energetics conformational analysis physical organic chemists use conformational analysis evaluate various types strain present molecule predict reaction products
Natural science Chemistry Physical organic chemistry