The Ehlers-Danlos syndromes comprise a clinically and genetically heterogeneous group of heritable connective tissue disorders characterized by articular hypermobility, skin extensibility, and tissue fragility. Surgical treatment of scoliosis associated with Ehlers-Danlos syndrome poses a challenge to spine surgeons because of the high risk of major complications. There is a paucity of evidence in the literature on surgical treatment for scoliosis in the Ehlers-Danlos syndrome patient.This article describes 3 adolescent patients diagnosed with Ehlers-Danlos syndrome, kyphoscoliosis type, which was treated by posterior spinal fusion only. After unsuccessful conservative treatment for at least 1 year, the patients underwent posterior spinal surgery for the correction of spinal deformity. A satisfactory correction in the spinal curve was achieved, with no obvious loss of correction during follow-up. No intra- or postoperative major complications were observed.Our experience supports that a satisfactory correction of scoliosis can be achieved by posterior spinal fusion only in patients with Ehlers-Danlos syndrome, kyphoscoliosis type.
The Ehlers - Danlos syndromes comprise a clinically and genetically heterogeneous group of heritable connective tissue disorders characterized by articular hypermobility , skin extensibility , and tissue fragility . Surgical treatment of scoliosis associated with Ehlers - Danlos syndrome poses a challenge to spine surgeons because of the high risk of major complications . There is a paucity of evidence in the literature on surgical treatment for scoliosis in the Ehlers - Danlos syndrome patient . This article describes 3 adolescent patients diagnosed with Ehlers - Danlos syndrome , kyphoscoliosis type , which was treated by posterior spinal fusion only . After unsuccessful conservative treatment for at least 1 year , the patients underwent posterior spinal surgery for the correction of spinal deformity . A satisfactory correction in the spinal curve was achieved , with no obvious loss of correction during follow - up . No intra- or postoperative major complications were observed . Our experience supports that a satisfactory correction of scoliosis can be achieved by posterior spinal fusion only in patients with Ehlers - Danlos syndrome , kyphoscoliosis type .
What tissue is most affected in Ehlers-Danlos syndromes?
What tissue is most affected in Ehlers - Danlos syndromes ?
connective tissue
connective tissue