To determine the validity of the rapid antigen test (RAT) OSOM StrepA Genzyme for the diagnosis of acute pharyngitis caused by group A beta-haemolytic strep (GABHS). Diagnostic techniques survey. Urban primary care centre, Spain. All patients over 14 years old seen in 6 surgeries with sore throat and 2 or more Centor criteria: pharyngotonsillar exudate, tender laterocervical nodes, absence of coughing, and/or history or presence of fever. Pharyngeal swabs were taken from all the patients, one for RAT and another to send for culture in the microbiology department. A total of 182 patients were evaluable, with a mean age of 30.6 (12.1) years of which 116 were women (63.7%); 63 patients had 2 Centor criteria; 83 had 3 and 36, the 4 criteria. The culture was positive in 102 patients (56%), with GABHS showing infection in forty (22%; 95% confidence interval [CI], 21.2-22.8). Group C Streptococcus was isolated in 26 patients (14.3%). GABHS was higher among patients with four Centor criteria (38.9% vs 25.3% observed among those with 3 criteria and 7.9% with 2 criteria; P<.001). Sensitivity of RAT was 95%, with a specificity of 93%, a positive predictive value of 79.2% and a negative predictive value of 98.5%. These results show the usefulness of RAT for diagnosing streptococcal pharyngitis. Its use should be spread to all primary care practices.
To determine the validity of the rapid antigen test ( RAT ) OSOM StrepA Genzyme for the diagnosis of acute pharyngitis caused by group A beta - haemolytic strep ( GABHS ) . Diagnostic techniques survey . Urban primary care centre , Spain . All patients over 14 years old seen in 6 surgeries with sore throat and 2 or more Centor criteria : pharyngotonsillar exudate , tender laterocervical nodes , absence of coughing , and/or history or presence of fever . Pharyngeal swabs were taken from all the patients , one for RAT and another to send for culture in the microbiology department . A total of 182 patients were evaluable , with a mean age of 30.6 ( 12.1 ) years of which 116 were women ( 63.7 % ) ; 63 patients had 2 Centor criteria ; 83 had 3 and 36 , the 4 criteria . The culture was positive in 102 patients ( 56 % ) , with GABHS showing infection in forty ( 22 % ; 95 % confidence interval [ CI ] , 21.2 - 22.8 ) . Group C Streptococcus was isolated in 26 patients ( 14.3 % ) . GABHS was higher among patients with four Centor criteria ( 38.9 % vs 25.3 % observed among those with 3 criteria and 7.9 % with 2 criteria ; P<.001 ) . Sensitivity of RAT was 95 % , with a specificity of 93 % , a positive predictive value of 79.2 % and a negative predictive value of 98.5 % . These results show the usefulness of RAT for diagnosing streptococcal pharyngitis . Its use should be spread to all primary care practices .
Centor criteria are used for which disease?
Centor criteria are used for which disease ?
streptococcal pharyngitis
streptococcal pharyngitis