Of London, between July and September Sydenham says: 'Aegri paroxysmus atrocior, lingua magis nigra siccaque, extra paroxysmum aporexia obscurio, virium et appetitus prostratio major, major item ad paroxysmum proclinitas, omnia summatim accidentia immanioria, ipseque morbus quam pro more Febrium intermittentium funestior'.