A direction indicated by figures whose level of organization becomes weaker and weaker; first, the morphology becomes blurred (irregular ossifications); then intra organic difli ren tiations occur (cirrhosis, hepatization of the lung); finally, the internal cohesion of the tissue disappears: when it is inflamed, the cellular sheath of the arteries 'allows itself to he cut like lard',' and the tissue of the liver may be pulled away with no effort.