One can easily see that wine has a variety of effects by observing how it gradually changes those who drink it; for, finding them chilled and taciturn as the result of abstinence, a small quantity makes them more talkative, while a larger quantity makes them eloquent and bold, and, when they proceed to action, reckless, and a still larger quantity makes them insolent and afterwards frenzied, while outrageous excess enfeebles them and makes them stupid like those who have been epileptic from childhood, and very similar to those who are exceedingly atrabilious.